NO2010022I1 - Denosumab - Google Patents
DenosumabInfo
- Publication number
- NO2010022I1 NO2010022I1 NO2010022C NO2010022C NO2010022I1 NO 2010022 I1 NO2010022 I1 NO 2010022I1 NO 2010022 C NO2010022 C NO 2010022C NO 2010022 C NO2010022 C NO 2010022C NO 2010022 I1 NO2010022 I1 NO 2010022I1
- Authority
- NO
- Norway
- Prior art keywords
- denosumab
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Education & Sports Medicine (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Wood Science & Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Plant Pathology (AREA)
- Hematology (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/842,842 US5843678A (en) | 1997-04-16 | 1997-04-16 | Osteoprotegerin binding proteins |
| US88085597A | 1997-06-23 | 1997-06-23 | |
| US09/052,521 US6316408B1 (en) | 1997-04-16 | 1998-03-30 | Methods of use for osetoprotegerin binding protein receptors |
| PCT/US1998/007584 WO1998046751A1 (en) | 1997-04-16 | 1998-04-15 | Osteoprotegerin binding proteins and receptors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO2010022I1 true NO2010022I1 (no) | 2011-01-10 |
| NO2010022I2 NO2010022I2 (no) | 2015-03-30 |
Family
ID=27126366
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO2010022C NO2010022I2 (no) | 1997-04-16 | 2010-11-25 | Denosumab |
Country Status (15)
| Country | Link |
|---|---|
| US (4) | US6316408B1 (no) |
| EP (1) | EP2311955A3 (no) |
| JP (2) | JP2009001566A (no) |
| KR (2) | KR101328809B1 (no) |
| CN (1) | CN103990122B (no) |
| CA (1) | CA2706609A1 (no) |
| CY (1) | CY1108998T1 (no) |
| GE (1) | GEP20033002B (no) |
| IL (1) | IL132304A (no) |
| LT (1) | LTC0975754I2 (no) |
| ME (2) | MEP32808A (no) |
| NO (1) | NO2010022I2 (no) |
| PT (1) | PT975754E (no) |
| RO (1) | RO122495B1 (no) |
| RS (1) | RS50358B (no) |
Families Citing this family (83)
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|---|---|---|---|---|
| IL117175A (en) * | 1995-02-20 | 2005-11-20 | Sankyo Co | Osteoclastogenesis inhibitory factor protein |
| PT1114864E (pt) * | 1996-12-13 | 2008-10-08 | Schering Corp | Antigénios de superfície de células de mamífero, reagentes relacionados |
| EP2003203A1 (en) | 1996-12-23 | 2008-12-17 | Immunex Corporation | Ligand for receptor activator of nf-kappa b, ligand is member of TNF superfamily |
| DK0911342T4 (da) * | 1997-04-15 | 2013-07-29 | Daiichi Sankyo Co Ltd | Nyt protein og fremgangsmåde til fremstilling deraf |
| BR9808545A (pt) | 1997-04-16 | 2000-05-23 | Amgen Inc | ácido nucleico isolado, vetor de expressão, célula hospedeira, processos para produzir uma proteìna de ligação da osteoprotegerina, para detectar a presença de uma proteìna de ligação à osteoprotegerina em uma amostra biológica, para avaliar a capacidade de um composto candidato de ligar-se a uma proteìna de ligação da osteoprotegerina e de um composto de teste para aumentar ou reduzir a ligação da proteìna de ligação da osteoprotegerina a odar, para regular a expressão de uma proteìna de ligação da osteoprotegerina em um animal e para prevenir ou tratar de doença óssea em um mamìfero, polipeptìdeo, protéina de ligação da osteroprotegerina purificada e isolada, ou seu fragmento, análogo ou derivado, e, anticorpo ou seu fragmento |
| US6316408B1 (en) * | 1997-04-16 | 2001-11-13 | Amgen Inc. | Methods of use for osetoprotegerin binding protein receptors |
| PT2009025E (pt) * | 1998-05-14 | 2011-09-19 | Immunex Corp | Método de inibição da actividade dos osteoclastos |
| US6540722B1 (en) | 1999-12-30 | 2003-04-01 | Advanced Cardiovascular Systems, Inc. | Embolic protection devices |
| US20030103978A1 (en) * | 2000-02-23 | 2003-06-05 | Amgen Inc. | Selective binding agents of osteoprotegerin binding protein |
| DE60129254T2 (de) * | 2000-09-22 | 2008-03-13 | Immunex Corp., Thousand Oaks | Screeningverfahren für agonisten und antagonisten des rezeptoraktivators von nf-kappa b |
| SI1365769T1 (sl) * | 2001-02-06 | 2011-06-30 | Sydney Children S Hospitals Network Randwick And Westmead Incorporating The Royal Alexandra Hospital | Zdravilo za zdravljenje osteonekroze za oskrbo pacientov pri tveganju razvoja osteonekroze |
| US20040132971A1 (en) * | 2001-02-09 | 2004-07-08 | Haaning Jesper Mortensen | Rank ligand-binding polypeptides |
| AU2002231602A1 (en) * | 2001-02-09 | 2002-08-28 | Maxygen Holdings Ltd. | Rank ligand-binding polypeptides |
| MXPA03011270A (es) * | 2001-06-06 | 2004-03-18 | Immunex Corp | Uso de antagonistas rank para tratar cancer. |
| PH12012502439A1 (en) | 2001-06-26 | 2013-06-17 | Amgen Inc | Antibodies to opgl |
| US6638294B1 (en) | 2001-08-30 | 2003-10-28 | Advanced Cardiovascular Systems, Inc. | Self furling umbrella frame for carotid filter |
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| US8262689B2 (en) | 2001-09-28 | 2012-09-11 | Advanced Cardiovascular Systems, Inc. | Embolic filtering devices |
| US20030109444A1 (en) * | 2001-10-12 | 2003-06-12 | Jonathan Lam | Bone anti-resorptive compounds |
| US7241304B2 (en) | 2001-12-21 | 2007-07-10 | Advanced Cardiovascular Systems, Inc. | Flexible and conformable embolic filtering devices |
| US7381792B2 (en) * | 2002-01-04 | 2008-06-03 | Xencor, Inc. | Variants of RANKL protein |
| US20040170602A1 (en) * | 2002-01-04 | 2004-09-02 | Desjarlais John R. | Dominant negative proteins and methods thereof |
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| JP4761710B2 (ja) | 2002-04-05 | 2011-08-31 | アムジェン インコーポレイテッド | 選択的opgl経路インヒビターとしてのヒト抗opgl中和抗体 |
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| US7259143B2 (en) * | 2002-09-05 | 2007-08-21 | Wisconsin Alumni Research Foundation | Method of extending the dose range of vitamin D compounds |
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| US8895540B2 (en) | 2003-11-26 | 2014-11-25 | DePuy Synthes Products, LLC | Local intraosseous administration of bone forming agents and anti-resorptive agents, and devices therefor |
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| JP6159254B2 (ja) | 2010-10-06 | 2017-07-12 | フンダシオ インスティトゥト デ レセルカ ビオメディカ(イエレベ バルセロナ) | 乳がん転移の診断、予後診断、および処置のための方法 |
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| GB201118840D0 (en) | 2011-11-01 | 2011-12-14 | Univ Sheffield | Pulmonary hypertension II |
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| WO2013182912A2 (en) | 2012-06-06 | 2013-12-12 | Fundacio Privada Institut De Recerca Biomedica | Method for the diagnosis, prognosis and treatment of lung cancer metastasis |
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| US10119171B2 (en) | 2012-10-12 | 2018-11-06 | Inbiomotion S.L. | Method for the diagnosis, prognosis and treatment of prostate cancer metastasis |
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| EP3041863A4 (en) | 2013-09-05 | 2017-08-16 | Amgen Inc. | Fc-containing molecules exhibiting predictable, consistent, and reproducible glycoform profiles |
| KR20160061424A (ko) | 2013-10-09 | 2016-05-31 | 펀다시오 인스티튜트 드 르세르카 바이오메디카 (아이알비 바르셀로나) | 유방암으로부터 기원하는 골의 전이성 암의 예후 및 치료 방법 |
| US10373702B2 (en) * | 2014-03-27 | 2019-08-06 | Massachusetts Institute Of Technology | Water-soluble trans-membrane proteins and methods for the preparation and use thereof |
| HRP20251500T1 (hr) | 2014-03-28 | 2026-01-02 | Duke University | Liječenje raka dojke pozitivnog na receptor estrogena uporabom selektivnih modulatora receptora estrogena |
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-
1998
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- 1998-04-15 GE GEAP19985034A patent/GEP20033002B/en unknown
- 1998-04-15 ME MEP-328/08A patent/MEP32808A/xx unknown
- 1998-04-15 PT PT98918244T patent/PT975754E/pt unknown
- 1998-04-15 KR KR1020127021477A patent/KR101328809B1/ko not_active Expired - Lifetime
- 1998-04-15 KR KR1019997009492A patent/KR101314478B1/ko not_active Expired - Lifetime
- 1998-04-15 ME MEP-2008-328A patent/ME00184B/me unknown
- 1998-04-15 EP EP10184791A patent/EP2311955A3/en not_active Withdrawn
- 1998-04-15 CA CA2706609A patent/CA2706609A1/en not_active Abandoned
- 1998-04-15 RO RO99-01101A patent/RO122495B1/ro unknown
- 1998-04-15 RS YUP-506/99A patent/RS50358B/sr unknown
- 1998-04-15 CN CN201310463795.5A patent/CN103990122B/zh not_active Expired - Lifetime
- 1998-12-14 US US09/211,315 patent/US7097834B1/en not_active Expired - Lifetime
- 1998-12-14 US US09/211,297 patent/US7807795B2/en not_active Expired - Fee Related
-
1999
- 1999-10-08 IL IL132304A patent/IL132304A/en active Protection Beyond IP Right Term
-
2004
- 2004-04-15 US US10/825,898 patent/US20050003400A1/en not_active Abandoned
-
2007
- 2007-06-21 CY CY20071100833T patent/CY1108998T1/el unknown
-
2008
- 2008-06-11 JP JP2008153218A patent/JP2009001566A/ja not_active Withdrawn
-
2010
- 2010-11-24 LT LTPA2010013C patent/LTC0975754I2/lt unknown
- 2010-11-25 NO NO2010022C patent/NO2010022I2/no unknown
-
2012
- 2012-09-13 JP JP2012201172A patent/JP2013028622A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN103990122B (zh) | 2017-01-04 |
| CN103990122A (zh) | 2014-08-20 |
| ME00184B (me) | 2010-10-10 |
| IL132304A (en) | 2015-07-30 |
| CY1108998T1 (el) | 2014-07-02 |
| YU50699A (sh) | 2000-10-30 |
| KR20120108046A (ko) | 2012-10-04 |
| PT975754E (pt) | 2007-08-20 |
| KR20010006405A (ko) | 2001-01-26 |
| GEP20033002B (en) | 2003-06-25 |
| US20030100488A1 (en) | 2003-05-29 |
| LTC0975754I2 (lt) | 2022-03-25 |
| NO2010022I2 (no) | 2015-03-30 |
| JP2013028622A (ja) | 2013-02-07 |
| RS50358B (sr) | 2009-11-10 |
| JP2009001566A (ja) | 2009-01-08 |
| US7097834B1 (en) | 2006-08-29 |
| CA2706609A1 (en) | 1998-10-22 |
| EP2311955A2 (en) | 2011-04-20 |
| EP2311955A3 (en) | 2012-12-12 |
| KR101328809B1 (ko) | 2014-01-17 |
| KR101314478B1 (ko) | 2014-01-17 |
| RO122495B1 (ro) | 2009-07-30 |
| US20050003400A1 (en) | 2005-01-06 |
| US6316408B1 (en) | 2001-11-13 |
| MEP32808A (en) | 2010-10-10 |
| LTPA2010013I1 (lt) | 2021-05-25 |
| US7807795B2 (en) | 2010-10-05 |
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