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NO991151L - Forbindelse og anvendelse derav - Google Patents

Forbindelse og anvendelse derav

Info

Publication number
NO991151L
NO991151L NO991151A NO991151A NO991151L NO 991151 L NO991151 L NO 991151L NO 991151 A NO991151 A NO 991151A NO 991151 A NO991151 A NO 991151A NO 991151 L NO991151 L NO 991151L
Authority
NO
Norway
Prior art keywords
compound
lamotrigine
triazin
amino
sample
Prior art date
Application number
NO991151A
Other languages
English (en)
Other versions
NO991151D0 (no
Inventor
Lorraine Mary Edmeades
Nigel Arthur Griffith-Skinner
Derek Anthony Hill
Graham Thronton Hill
Terence William Packham
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10833464&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO991151(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of NO991151D0 publication Critical patent/NO991151D0/no
Publication of NO991151L publication Critical patent/NO991151L/no

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D253/075—Two hetero atoms, in positions 3 and 5
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/90—Plate chromatography, e.g. thin layer or paper chromatography
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/145555—Hetero-N
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/145555—Hetero-N
    • Y10T436/147777—Plural nitrogen in the same ring [e.g., barbituates, creatinine, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Fremgangsmåte for å teste renheten eller stabiliteten til degradering av en prøve av lamotrigin eller en farmasøytisk doseringsform omfattende lamotrigin omfattende analysering av nevnte prøve for tilstedeværelse av forbindelse valgt fra 3-amino-6-(2,3-diklorfenyl)-1,2,4-triazin-5-(4H)-on (forbindelse A) og N-(5-amino-6-(Z^iklorfenyO-l^^-triazin-S-yll^^diklorbenzamid (forbindelse B). En fremgangsmåte for fremstilling B, som er ny, er også beskrevet.
NO991151A 1998-06-10 1999-03-10 Forbindelse og anvendelse derav NO991151L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9812413.4A GB9812413D0 (en) 1998-06-10 1998-06-10 Compound and its use

Publications (2)

Publication Number Publication Date
NO991151D0 NO991151D0 (no) 1999-03-10
NO991151L true NO991151L (no) 1999-12-13

Family

ID=10833464

Family Applications (2)

Application Number Title Priority Date Filing Date
NO991151A NO991151L (no) 1998-06-10 1999-03-10 Forbindelse og anvendelse derav
NO20032753A NO20032753D0 (no) 1998-06-10 2003-06-17 Forbindelse og anvendelse derav

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO20032753A NO20032753D0 (no) 1998-06-10 2003-06-17 Forbindelse og anvendelse derav

Country Status (31)

Country Link
US (1) US6333198B1 (no)
EP (2) EP1170588A1 (no)
JP (1) JP2989189B1 (no)
KR (1) KR100322354B1 (no)
CN (2) CN1238454A (no)
AP (3) AP0102286A0 (no)
AR (1) AR014074A1 (no)
AT (1) ATE218552T1 (no)
AU (1) AU2031999A (no)
BR (1) BR9900984A (no)
CA (1) CA2265194C (no)
DE (1) DE69901656T2 (no)
DK (1) DK0963980T3 (no)
EA (1) EA000666B1 (no)
ES (1) ES2178342T3 (no)
GB (1) GB9812413D0 (no)
HR (1) HRP990074A2 (no)
HU (1) HUP9900592A3 (no)
ID (1) ID22957A (no)
MA (1) MA24777A1 (no)
NO (2) NO991151L (no)
NZ (1) NZ334590A (no)
PE (1) PE20000332A1 (no)
PL (1) PL331870A1 (no)
PT (1) PT963980E (no)
SG (1) SG85628A1 (no)
SI (1) SI0963980T1 (no)
TR (1) TR199900520A3 (no)
UY (1) UY25946A1 (no)
YU (1) YU12399A (no)
ZA (1) ZA991951B (no)

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US20080242877A1 (en) * 2007-02-26 2008-10-02 Vinod Kumar Kansal Intermediates and processes for the synthesis of Ramelteon
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CN102766104A (zh) * 2012-08-20 2012-11-07 三金集团湖南三金制药有限责任公司 一种治疗双向情感障碍及癫痫病药物拉莫三嗪的合成方法
US10189859B2 (en) 2013-12-21 2019-01-29 Nektar Therapeutics Derivatives of 6-(2,3-dichlorophenyl)-1,2,4-triazin-5-amine
CN110467560B (zh) 2018-05-09 2025-11-25 深圳微芯生物科技股份有限公司 一种苯基氨基丙酸钠衍生物、其制备方法和应用
KR102270026B1 (ko) * 2020-01-31 2021-06-28 현대약품 주식회사 (3s)-3-(4-(3-(1,4-다이옥사스파이로[4,5]데스-7-엔-8-일)벤질옥시)페닐)헥스-4-이노익산의 품질 평가 방법
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EP0021120B1 (en) 1979-06-01 1983-04-06 The Wellcome Foundation Limited 3,5-diamino-1,2,4-triazine derivatives, process for preparing such compounds and pharmaceutical compositions containing them
GB8613183D0 (en) 1986-05-30 1986-07-02 Wellcome Found Triazine salt
GB9426448D0 (en) * 1994-12-30 1995-03-01 Wellcome Found Process
WO1996020934A1 (en) * 1994-12-30 1996-07-11 The Wellcome Foundation Limited Process for the preparation of lamotrigine
GB9512854D0 (en) * 1995-06-23 1995-08-23 Wellcome Found Novel formulation

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DE69901656D1 (de) 2002-07-11
US6333198B1 (en) 2001-12-25
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EA000666B1 (ru) 2000-02-28
ID22957A (id) 1999-12-23
NO991151D0 (no) 1999-03-10
CN1306210A (zh) 2001-08-01
PL331870A1 (en) 1999-12-20
KR100322354B1 (ko) 2002-02-07
TR199900520A2 (en) 2000-01-21
EP0963980B1 (en) 2002-06-05
PT963980E (pt) 2002-10-31
ATE218552T1 (de) 2002-06-15
ES2178342T3 (es) 2002-12-16
EP1170588A1 (en) 2002-01-09
SI0963980T1 (en) 2002-12-31
HUP9900592A2 (hu) 2000-04-28
PE20000332A1 (es) 2000-04-10
CN1238454A (zh) 1999-12-15
HUP9900592A3 (en) 2002-04-29
TR199900520A3 (tr) 2000-01-21
AU2031999A (en) 2000-01-06
EA199900159A1 (ru) 1999-12-29
KR20000005611A (ko) 2000-01-25
DE69901656T2 (de) 2003-01-30
JP2989189B1 (ja) 1999-12-13
BR9900984A (pt) 2000-05-02
EP0963980A3 (en) 2000-05-31
EP0963980A2 (en) 1999-12-15
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ZA991951B (en) 1999-08-16
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AR014074A1 (es) 2001-01-31
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