MA22907A1 - Nouveau procede de preparation d'acide clavulanique. - Google Patents

Nouveau procede de preparation d'acide clavulanique.

Info

Publication number: MA22907A1
Authority: MA; Morocco
Prior art keywords: preparation; new process; clavulanic acid; clavulanic; acid
Prior art date: 1992-06-11

Application number

MA23206A

Other languages

English (en)

Inventor

Bennett Wilkins Robert

Allen Cook Michael

Original Assignee

Smithkline Beecham Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-06-11

Filing date

1993-06-09

Publication date

1993-12-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27450891&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA22907(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1992-06-11 Priority claimed from GB929212379A external-priority patent/GB9212379D0/en

1992-10-31 Priority claimed from GB929222841A external-priority patent/GB9222841D0/en

1992-12-14 Priority claimed from GB929226061A external-priority patent/GB9226061D0/en

1992-12-17 Priority claimed from GB929226282A external-priority patent/GB9226282D0/en

1993-06-09 Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc

1993-12-31 Publication of MA22907A1 publication Critical patent/MA22907A1/fr

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- B—PERFORMING OPERATIONS; TRANSPORTING
- B60—VEHICLES IN GENERAL
- B60C—VEHICLE TYRES; TYRE INFLATION; TYRE CHANGING; CONNECTING VALVES TO INFLATABLE ELASTIC BODIES IN GENERAL; DEVICES OR ARRANGEMENTS RELATED TO TYRES
- B60C27/00—Non-skid devices temporarily attachable to resilient tyres or resiliently-tyred wheels
- B60C27/006—Non-skid devices temporarily attachable to resilient tyres or resiliently-tyred wheels provided with protective parts, e.g. rubber elements to protect the rim portion
- B—PERFORMING OPERATIONS; TRANSPORTING
- B60—VEHICLES IN GENERAL
- B60C—VEHICLE TYRES; TYRE INFLATION; TYRE CHANGING; CONNECTING VALVES TO INFLATABLE ELASTIC BODIES IN GENERAL; DEVICES OR ARRANGEMENTS RELATED TO TYRES
- B60C27/00—Non-skid devices temporarily attachable to resilient tyres or resiliently-tyred wheels
- B60C27/06—Non-skid devices temporarily attachable to resilient tyres or resiliently-tyred wheels extending over the complete circumference of the tread, e.g. made of chains or cables

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Mechanical Engineering (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Cephalosporin Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

MA23206A 1992-06-11 1993-06-09 Nouveau procede de preparation d'acide clavulanique. MA22907A1 (fr)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GB929212379A GB9212379D0 (en)	1992-06-11	1992-06-11	Novel process
GB929222841A GB9222841D0 (en)	1992-10-31	1992-10-31	Novel process
GB929226061A GB9226061D0 (en)	1992-12-14	1992-12-14	Novel process
GB929226282A GB9226282D0 (en)	1992-12-17	1992-12-17	Novel process

Publications (1)

Publication Number	Publication Date
MA22907A1 true MA22907A1 (fr)	1993-12-31

Family

ID=27450891

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MA23206A MA22907A1 (fr)	1992-06-11	1993-06-09	Nouveau procede de preparation d'acide clavulanique.

Country Status (35)

Country	Link
EP (7)	EP0801069A1 (fr)
JP (3)	JPH07507324A (fr)
KR (1)	KR0162264B1 (fr)
CN (3)	CN1037967C (fr)
AP (3)	AP474A (fr)
AT (3)	ATE134192T1 (fr)
AU (3)	AU4342793A (fr)
BG (3)	BG61306B1 (fr)
CA (2)	CA2117538A1 (fr)
CS (1)	CS202194A3 (fr)
CY (1)	CY1895A (fr)
CZ (5)	CZ267694A3 (fr)
DE (6)	DE69306574T2 (fr)
DK (5)	DK0644887T3 (fr)
ES (3)	ES2106615T3 (fr)
FI (7)	FI980630A0 (fr)
GB (2)	GB2287025B (fr)
GR (4)	GR950300070T1 (fr)
HK (1)	HK6996A (fr)
HU (3)	HU212583B (fr)
IL (1)	IL105966A (fr)
LU (1)	LU88567A1 (fr)
MA (1)	MA22907A1 (fr)
MX (1)	MX9303441A (fr)
MY (1)	MY131501A (fr)
NL (1)	NL9320037A (fr)
NO (3)	NO943093L (fr)
PT (2)	PT101710A (fr)
RO (3)	RO111192B1 (fr)
RU (1)	RU2081121C1 (fr)
SE (5)	SE9404290L (fr)
SI (1)	SI9300296B (fr)
SK (3)	SK278561B6 (fr)
UY (1)	UY24154A1 (fr)
WO (1)	WO1993025557A1 (fr)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AT400033B (de)	1992-03-10	1995-09-25	Biochemie Gmbh	Neues verfahren zur isolierung und reinigung von clavulansäure und zur herstellung von pharmakologisch verträglichen salzen derselben
AT399155B (de) *	1992-03-26	1995-03-27	Lek Tovarna Farmacevtskih	Neue alkylendiammonium-diclavulanat-derivate, verfahren zu deren herstellung sowie deren verwendung
SI9300296B (sl) *	1992-06-11	1998-06-30	Smithkline Beecham P.L.C.	Postopek in intermedianti za pripravo klavulanske kisline
KR100200239B1 (ko) *	1992-10-21	1999-06-15	김충환	클라불란산 칼륨염의 제조방법
US5741903A (en) *	1993-03-26	1998-04-21	Gist-Brocades N.V.	Diamine salts for purification of clavulanic acid
ATE140703T1 (de) *	1993-03-26	1996-08-15	Gist Brocades Nv	Diaminsalze von clavulansäure
US5821364A (en) *	1993-03-26	1998-10-13	Gist-Brocades N.V.	Diamine salts of clavulanic acid
JP2839955B2 (ja)	1993-03-26	1998-12-24	ギストブロカデスナムローゼフェンノートシャップ	クラブラン酸のジアミン塩
US5760218A (en) *	1993-03-26	1998-06-02	Gist-Brocades N.V.	Diamine salts of clavulanic acid
EP0658558B1 (fr)	1993-11-17	2001-01-24	Biochemie Gesellschaft M.B.H.	Séparation d'isomères d'un dérivé de la céphalosporin
SI9400107A (en)	1994-03-02	1995-10-31	Lek Tovarna Farmacevtskih	New process of the isolation of clavulanic acid and its pharmaceutical salts from fermented broth of streptomyces sp.p 6621 ferm p 2804.
GB9426261D0 (en) *	1994-12-24	1995-02-22	Spurcourt Ltd	Clavulanic acid salts
MD1744F2 (ro) *	1995-02-25	2001-09-30	Spurcourt Limited	Săruri ale acidului clavulanic şi procedeu de obţinere a lor
SI9500134B (sl)	1995-04-20	2004-04-30	Lek,	Postopek za pripravo čistih alkalijskih soli klavulanske kisline
GB9515809D0 (en) *	1995-08-02	1995-10-04	Smithkline Beecham Plc	Process
SI9500265A1 (en)	1995-08-28	1997-02-28	Lek Tovarna Farmacevtskih	Process for purification of the aqueous fermented broth filtrate of streptomyces sp. p 6621 ferm p 2804 by ultrafiltration
AT403375B (de) *	1995-11-15	1998-01-26	Biochemie Gmbh	Verfahren zur fällung von alkalisalzen der clavulansäure
US6414142B1 (en) *	1996-06-13	2002-07-02	Smithkline Beecham Corporation	Process for preparing potassium clavulanate
CA2271847A1 (fr) *	1996-11-11	1998-05-22	Gist-Brocades B.V.	Procede de preparation de sels et d'esters d'acide clavulanique
AT404728B (de) *	1996-11-27	1999-02-25	Biochemie Gmbh	Verfahren zur herstellung von clavulansäure-aminsalzen
DZ2456A1 (fr)	1997-04-04	2003-01-18	Smithkline Beecham Plc	Procédé de préparation de sels de l'acide clavulanique.
CN1312814A (zh) *	1998-07-16	2001-09-12	Dsm公司	制备棒酸盐类及其酯类的改进方法
US6440708B1 (en)	1998-09-29	2002-08-27	Dsm N.V.	Fermentation of clavulanic acid at a controlled level of ammonia
DE19917428A1 (de) *	1999-04-19	2000-10-26	Clariant Gmbh	Flammwidrige phosphormodifizierte Epoxidharze
GB0003305D0 (en)	2000-02-15	2000-04-05	Zeneca Ltd	Pyrimidine derivatives
KR100827898B1 (ko)	2000-05-13	2008-05-07	스미스클라인비이참피이엘시이	클라불란산의 염의 정제 방법
ITMI20011764A1 (it)	2001-08-10	2003-02-10	Dinamite Dipharma Spa	Metodo per l'ottenimento del pemirolast ad elevata purezza
GB201010439D0 (en) *	2010-06-21	2010-08-04	Arch Timber Protection Ltd	A method
CN103304583B (zh) *	2013-07-09	2016-01-20	山东新时代药业有限公司	一种从克拉维酸胺盐结晶母液中回收克拉维酸的方法
CN105384758B (zh) *	2015-12-01	2018-05-01	国药集团威奇达药业有限公司	克拉维酸胺盐的制备方法
CN110573637B (zh)	2017-04-19	2022-02-18	日本轻金属株式会社	Al－Si－Fe系铝合金铸造材料及其制造方法
CN109305978A (zh) *	2017-07-26	2019-02-05	山东睿鹰先锋制药有限公司	一种制备克拉维酸盐的新方法
CN116283498B (zh) *	2023-03-07	2025-02-28	国药集团威奇达药业有限公司	从克拉维酸钾生产废液中回收有机溶剂的方法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1508977A (en)	1974-04-20	1978-04-26	Beecham Group Ltd	Beta-lactam antibiotic from streptomyces clavuligerus
GB1507978A (en)	1974-03-28	1978-04-19	Dunlop Ltd	Pneumatic tyre and wheel rim assemblies
GB1543563A (en) *	1975-02-07	1979-04-04	Glaxo Lab Ltd	Beta-lactam antibiotic in purified form
GB1508978A (en)	1975-04-11	1978-04-26	Beecham Group Ltd	Esters of clavulanic acid
GB1578739A (en) *	1976-07-23	1980-11-05	Beecham Group Ltd	Amine salts of clavulanic acid methods for their preparation and compositions containing them
EP0002312B1 (fr) *	1977-11-26	1982-02-03	Beecham Group Plc	Dérivés de l'acide clavulanique et compositions pharmaceutiques les contenant
BE862211A (fr) *	1977-12-22	1978-06-22	Beecham Group Ltd	Agents antibacteriens
JPS5562993A (en)	1978-11-07	1980-05-12	Idemitsu Petrochem Co Ltd	Operation of olefin manufacturing equipment
JPS55162993A (en) *	1979-06-07	1980-12-18	Sanraku Inc	Preparation of culavulanic acid
DE3063683D1 (en)	1979-08-24	1983-07-14	Beecham Group Plc	Amine salt of clavulanic acid, its preparation and use
AR245221A1 (es) *	1984-10-27	1993-12-30	Beecham Group Plc	Un metodo para la produccion de acido clavulanico por fermentacion de s. clavuligerus
ES2010143A6 (es) *	1989-03-01	1989-10-16	Pharma Mar S A Pharmar	Un nuevo procedimiento de obtencion del acido z(2r,5r)-3-(2-hiadroxietiliden)-7- oxo-4-oxa-1-azabiciclo(3,2,0) -heptano-2-carboxilico y de sales estares farmaceutiacamente aceptables del mismo,a partir de caldos de fermentacion de streptomyces, sp.
FR2644543A1 (fr)	1989-03-17	1990-09-21	Renault
PT94908B (pt)	1990-08-03	1998-05-29	Portela & Ca Lda	Processo para a preparacao de derivados carboxilicos beta-lactamicos altamente purificados estaveis e hipoalergenicos
AT400033B (de) *	1992-03-10	1995-09-25	Biochemie Gmbh	Neues verfahren zur isolierung und reinigung von clavulansäure und zur herstellung von pharmakologisch verträglichen salzen derselben
AT399155B (de) *	1992-03-26	1995-03-27	Lek Tovarna Farmacevtskih	Neue alkylendiammonium-diclavulanat-derivate, verfahren zu deren herstellung sowie deren verwendung
SI9300296B (sl) *	1992-06-11	1998-06-30	Smithkline Beecham P.L.C.	Postopek in intermedianti za pripravo klavulanske kisline
KR100200239B1 (ko) *	1992-10-21	1999-06-15	김충환	클라불란산 칼륨염의 제조방법
GB9305565D0 (en) *	1993-03-18	1993-05-05	Smithkline Beecham Plc	Novel compounds and processes
ATE140703T1 (de) *	1993-03-26	1996-08-15	Gist Brocades Nv	Diaminsalze von clavulansäure
EP0887178A1 (fr)	1997-06-27	1998-12-30	Pamag Ag	Procédé de cerclage de sacs à soufflets latéraux et dispositif pour la réalisation du procédé

1993
- 1993-06-03 SI SI9300296A patent/SI9300296B/sl unknown
- 1993-06-07 RO RO95-00659A patent/RO111192B1/ro unknown
- 1993-06-07 ES ES95201084T patent/ES2106615T3/es not_active Expired - Lifetime
- 1993-06-07 RO RO94-01806A patent/RO111191B1/ro unknown
- 1993-06-07 SK SK994-94A patent/SK278561B6/sk unknown
- 1993-06-07 AT AT95201085T patent/ATE134192T1/de not_active IP Right Cessation
- 1993-06-07 SK SK1533-94A patent/SK278367B6/sk unknown
- 1993-06-07 AT AT95201084T patent/ATE157981T1/de not_active IP Right Cessation
- 1993-06-07 CA CA002117538A patent/CA2117538A1/fr not_active Abandoned
- 1993-06-07 ES ES93913311T patent/ES2095059T3/es not_active Expired - Lifetime
- 1993-06-07 CS CZ942021A patent/CS202194A3/cs unknown
- 1993-06-07 DE DE69306574T patent/DE69306574T2/de not_active Expired - Fee Related
- 1993-06-07 HU HU9500610A patent/HU212583B/hu not_active IP Right Cessation
- 1993-06-07 AU AU43427/93A patent/AU4342793A/en not_active Abandoned
- 1993-06-07 RO RO95-00880A patent/RO111193B1/ro unknown
- 1993-06-07 EP EP97201652A patent/EP0801069A1/fr not_active Withdrawn
- 1993-06-07 WO PCT/GB1993/001206 patent/WO1993025557A1/fr not_active Ceased
- 1993-06-07 CZ CZ942676A patent/CZ267694A3/cs unknown
- 1993-06-07 FI FI980630A patent/FI980630A0/fi not_active Application Discontinuation
- 1993-06-07 CZ CZ96193A patent/CZ19396A3/cs unknown
- 1993-06-07 EP EP95201085A patent/EP0672670B1/fr not_active Revoked
- 1993-06-07 JP JP6501253A patent/JPH07507324A/ja active Pending
- 1993-06-07 DK DK93913311.2T patent/DK0644887T3/da active
- 1993-06-07 NL NL9320037A patent/NL9320037A/nl not_active Application Discontinuation
- 1993-06-07 EP EP93913311A patent/EP0644887B1/fr not_active Expired - Lifetime
- 1993-06-07 CZ CZ951254A patent/CZ281102B6/cs not_active IP Right Cessation
- 1993-06-07 GB GB9508496A patent/GB2287025B/en not_active Expired - Fee Related
- 1993-06-07 DE DE4392664T patent/DE4392664T1/de not_active Withdrawn
- 1993-06-07 CA CA002160768A patent/CA2160768A1/fr not_active Abandoned
- 1993-06-07 HU HU9402405A patent/HUT69374A/hu unknown
- 1993-06-07 PT PT101710A patent/PT101710A/pt not_active IP Right Cessation
- 1993-06-07 ES ES95201085T patent/ES2080710T3/es not_active Expired - Lifetime
- 1993-06-07 CZ CZ942675A patent/CZ267594A3/cs unknown
- 1993-06-07 HU HU9501214A patent/HU9501214D0/hu not_active Application Discontinuation
- 1993-06-07 DE DE4345286A patent/DE4345286A1/de not_active Ceased
- 1993-06-07 FI FI944031A patent/FI944031A7/fi not_active Application Discontinuation
- 1993-06-07 RU RU9595112522A patent/RU2081121C1/ru active
- 1993-06-07 FI FI982790A patent/FI982790A0/fi unknown
- 1993-06-07 KR KR1019940703225A patent/KR0162264B1/ko not_active Expired - Fee Related
- 1993-06-07 DE DE4345311A patent/DE4345311C1/de not_active Expired - Lifetime
- 1993-06-07 GB GB9508497A patent/GB2287026B/en not_active Expired - Fee Related
- 1993-06-07 SK SK1532-94A patent/SK278520B6/sk unknown
- 1993-06-07 EP EP97201887A patent/EP0806426A1/fr not_active Withdrawn
- 1993-06-07 PT PT101711A patent/PT101711A/pt not_active Application Discontinuation
- 1993-06-07 CZ CZ95544A patent/CZ54495A3/cs unknown
- 1993-06-07 EP EP95117448A patent/EP0699682A1/fr not_active Withdrawn
- 1993-06-07 EP EP95201084A patent/EP0672669B1/fr not_active Expired - Lifetime
- 1993-06-07 DK DK95201085.8T patent/DK0672670T3/da active
- 1993-06-07 AT AT93913311T patent/ATE146180T1/de not_active IP Right Cessation
- 1993-06-07 EP EP96202593A patent/EP0747383A3/fr not_active Withdrawn
- 1993-06-07 DE DE69301571T patent/DE69301571T2/de not_active Expired - Fee Related
- 1993-06-07 DK DK95201084.1T patent/DK0672669T3/da active
- 1993-06-07 FI FI980631A patent/FI980631L/fi not_active Application Discontinuation
- 1993-06-07 DE DE69313869T patent/DE69313869T2/de not_active Expired - Fee Related
- 1993-06-08 MY MYPI93001142A patent/MY131501A/en unknown
- 1993-06-09 MX MX9303441A patent/MX9303441A/es not_active IP Right Cessation
- 1993-06-09 MA MA23206A patent/MA22907A1/fr unknown
- 1993-06-09 IL IL105966A patent/IL105966A/xx not_active IP Right Cessation
- 1993-06-10 CN CN93106612A patent/CN1037967C/zh not_active Expired - Fee Related
- 1993-06-10 AP APAP/P/1995/000738A patent/AP474A/en active
- 1993-06-10 AP APAP/P/1993/000537A patent/AP471A/en active
- 1993-06-10 AP APAP/P/1995/000737A patent/AP473A/en active
1994
- 1994-08-22 NO NO943093A patent/NO943093L/no unknown
- 1994-10-20 BG BG99639/95A patent/BG61306B1/bg unknown
- 1994-10-20 BG BG99131A patent/BG60999B1/bg unknown
- 1994-12-07 LU LU88567A patent/LU88567A1/fr unknown
- 1994-12-08 DK DK140694A patent/DK140694A/da not_active Application Discontinuation
- 1994-12-09 SE SE9404290A patent/SE9404290L/xx not_active Application Discontinuation
1995
- 1995-02-27 NO NO950758A patent/NO950758D0/no unknown
- 1995-02-27 SE SE9500718A patent/SE9500718D0/xx not_active Application Discontinuation
- 1995-03-09 AU AU14737/95A patent/AU680099B2/en not_active Ceased
- 1995-03-24 FI FI951414A patent/FI103973B/fi active
- 1995-03-31 JP JP7075492A patent/JPH08134072A/ja active Pending
- 1995-04-26 SE SE9501544A patent/SE503077C2/sv not_active IP Right Cessation
- 1995-04-28 CN CN95104832A patent/CN1041934C/zh not_active Expired - Fee Related
- 1995-05-03 NO NO951725A patent/NO178499C/no not_active IP Right Cessation
- 1995-05-15 CN CN95104675A patent/CN1036592C/zh not_active Expired - Fee Related
- 1995-05-16 BG BG99640A patent/BG61190B1/bg unknown
- 1995-05-19 JP JP7121206A patent/JPH08157480A/ja active Pending
- 1995-06-08 FI FI952820A patent/FI96952C/fi active
- 1995-06-15 DK DK068595A patent/DK170569B1/da not_active IP Right Cessation
1996
- 1996-01-11 HK HK6996A patent/HK6996A/xx not_active IP Right Cessation
- 1996-01-30 UY UY24154A patent/UY24154A1/es unknown
- 1996-01-31 GR GR950300070T patent/GR950300070T1/el unknown
- 1996-02-15 GR GR960400402T patent/GR3019006T3/el unknown
- 1996-02-29 SE SE9600797A patent/SE504220C2/sv not_active IP Right Cessation
- 1996-04-22 FI FI961739A patent/FI104488B/fi active
- 1996-09-27 CY CY189596A patent/CY1895A/en unknown
- 1996-12-12 GR GR960403146T patent/GR3022006T3/el unknown
1997
- 1997-02-14 AU AU14716/97A patent/AU681569B3/en not_active Revoked
- 1997-09-09 GR GR970402308T patent/GR3024666T3/el unknown
- 1997-11-19 SE SE9704244A patent/SE9704244D0/xx unknown

Also Published As

Publication number	Publication date
ES2106615T3 (es)	1997-11-01
RO111193B1 (ro)	1996-07-30
HK6996A (en)	1996-01-19
SE9500718L (sv)	1995-02-27
NO943093D0 (no)	1994-08-22
CN1036592C (zh)	1997-12-03
RO111192B1 (ro)	1996-07-30
GB2287026B (en)	1995-11-01
KR950700914A (ko)	1995-02-20
CN1041934C (zh)	1999-02-03
ES2095059T3 (es)	1997-02-01
HUT69374A (en)	1995-09-28
CZ125495A3 (en)	1996-06-12
EP0672670A1 (fr)	1995-09-20
WO1993025557A1 (fr)	1993-12-23
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DK170569B1 (da)	1995-10-23
FI952820L (fi)	1995-06-08
FI951414A0 (fi)	1995-03-24
BG99639A (bg)	1996-02-28
RU95112522A (ru)	1997-02-10
AU680099B2 (en)	1997-07-17
SE9501544L (sv)	1995-04-26
DE69301571D1 (de)	1996-03-28
FI982790L (fi)	1998-12-23
CN1112928A (zh)	1995-12-06
EP0672670B1 (fr)	1996-02-14
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HK1007311A1 (en)	1999-04-09
CA2160768A1 (fr)	1993-12-12
IL105966A (en)	1997-09-30
SE9600797L (sv)	1996-02-29
MY131501A (en)	2007-08-30
JPH08157480A (ja)	1996-06-18
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MX9303441A (es)	1994-03-31
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CN1113244A (zh)	1995-12-13
HK1003222A1 (en)	1998-10-16
UY24154A1 (es)	1996-07-23

Publication	Publication Date	Title
MA22907A1 (fr)	1993-12-31	Nouveau procede de preparation d'acide clavulanique.
MA22626A1 (fr)	1993-04-01	Procede de preparation d'acides imidazolyl-alcenoiques .
MA22481A1 (fr)	1992-12-31	Procede de preparation d'acides imidazolyl - alcenoiques .
MA22668A1 (fr)	1993-07-01	Procede de preparation d'oxamides .
RO80265A (fr)	1983-04-29	Procede pour la preparation de derives de l'acide beta-carboline-3-carboxyliqye
FR2707087B1 (fr)	1995-10-13	Nouveau procédé de préparation de l'ergothionéine.
MA21413A1 (fr)	1989-07-01	Nouveau procede de preparation d'alcoxy-guanine
FR2550788B1 (fr)	1989-11-17	Nouveau procede de preparation d'a-6-desoxytetracyclines
FR2688506B1 (fr)	1995-06-23	Procede de preparation de sels de l'acide clavulanique.
RO79837A (fr)	1983-02-01	Procede pour la preparation de l'acide cyanhydrique
MA23036A1 (fr)	1994-07-01	Procede pour la preparation de composes.
FR2677354B1 (fr)	1993-09-03	Procede pour la preparation d'esters d'acides racemisables.
RO88451A2 (fr)	1986-01-30	Derives de l'acide 7-aminocephalosporanique et procede de preparation
FR2688505B1 (fr)	1994-05-06	Nouveau procede de preparation de 4-pyrimidinones.
FR2610924B1 (fr)	1990-05-04	Procede de preparation d'hydroxybiphenyles
BE896868A (fr)	1983-11-28	Procede de preparation d'acide acetique.
FR2673942B1 (fr)	1994-09-09	Procede de preparation de l'acide (e)-propyl-2 pentene-2 ouique et composes intermediaires.
FR2630741B1 (fr)	1993-12-31	Procede de preparation d'acryloyloxyethoxymethyl-melamines
MA22061A1 (fr)	1991-10-01	Procede pour la preparation de l'acide 7-amino-3-methoxy methyl-ceph-3-eme-4-carboxylique et son utilisation.
PT74813B (fr)	1983-10-26	Procede de preparation de derives de l'acide 1,4-thiazane-carboxylique
FR2542758B1 (fr)	1988-01-08	Procede de preparation de l'acide l-glutamique
FR2513638B1 (fr)	1985-06-28	Procede de preparation d'esters d'acides vincaminiques
FR2655646B1 (fr)	1992-01-17	Procede de preparation de diesters de l'acide hexenediouique.
FR2631027B1 (fr)	1992-07-03	Procede de preparation d'esters de l'acide n-cyanethanimidique
FR2686877B1 (fr)	1995-03-24	Procede de preparation de l'acide orthohydroxyphenylacetique.