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ZW2391A1 - N-(piperidinyl)(dihydrobenzofuran or dihydro-2h-benzopyran)carboxamide derivatives - Google Patents

N-(piperidinyl)(dihydrobenzofuran or dihydro-2h-benzopyran)carboxamide derivatives

Info

Publication number
ZW2391A1
ZW2391A1 ZW23/91A ZW2391A ZW2391A1 ZW 2391 A1 ZW2391 A1 ZW 2391A1 ZW 23/91 A ZW23/91 A ZW 23/91A ZW 2391 A ZW2391 A ZW 2391A ZW 2391 A1 ZW2391 A1 ZW 2391A1
Authority
ZW
Zimbabwe
Prior art keywords
aryl
alkyl
alk
cycloalkyl
piperidinyl
Prior art date
Application number
ZW23/91A
Other languages
English (en)
Inventor
Georges Henri Paul Van Daele
Jean-Paul Rene Marie Bosmans
Michel Anna Jozef De Cleyn
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of ZW2391A1 publication Critical patent/ZW2391A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10Laxatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrane Compounds (AREA)
  • Cosmetics (AREA)
ZW23/91A 1990-03-06 1991-03-05 N-(piperidinyl)(dihydrobenzofuran or dihydro-2h-benzopyran)carboxamide derivatives ZW2391A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909005014A GB9005014D0 (en) 1990-03-06 1990-03-06 N.(4.piperidinyl)(dihydrobenzofuran or dihydro.2h.benzopyran)carboxamide derivatives

Publications (1)

Publication Number Publication Date
ZW2391A1 true ZW2391A1 (en) 1992-09-07

Family

ID=10672103

Family Applications (1)

Application Number Title Priority Date Filing Date
ZW23/91A ZW2391A1 (en) 1990-03-06 1991-03-05 N-(piperidinyl)(dihydrobenzofuran or dihydro-2h-benzopyran)carboxamide derivatives

Country Status (38)

Country Link
US (2) US5185335A (xx)
EP (1) EP0445862B1 (xx)
JP (1) JP2601566B2 (xx)
KR (1) KR0177521B1 (xx)
CN (1) CN1038936C (xx)
AT (1) ATE191912T1 (xx)
AU (1) AU636012B2 (xx)
BG (1) BG60381B1 (xx)
CA (1) CA2037575C (xx)
CY (1) CY2235B1 (xx)
CZ (1) CZ286617B6 (xx)
DE (1) DE69132119T2 (xx)
DK (1) DK0445862T3 (xx)
ES (1) ES2147175T3 (xx)
FI (1) FI101622B1 (xx)
GB (1) GB9005014D0 (xx)
GR (1) GR3033461T3 (xx)
HR (1) HRP930483B1 (xx)
HU (2) HU221627B1 (xx)
IE (1) IE910710A1 (xx)
IL (1) IL97018A (xx)
LT (1) LT3708B (xx)
LV (1) LV10085B (xx)
MA (1) MA22076A1 (xx)
MY (1) MY108831A (xx)
NO (1) NO177424C (xx)
NZ (1) NZ237189A (xx)
PL (6) PL168686B1 (xx)
PT (1) PT96937B (xx)
RU (1) RU2070884C1 (xx)
SG (1) SG47482A1 (xx)
SI (1) SI9110396B (xx)
SK (2) SK282407B6 (xx)
TN (1) TNSN91010A1 (xx)
UA (1) UA25969A1 (xx)
YU (1) YU48854B (xx)
ZA (1) ZA911611B (xx)
ZW (1) ZW2391A1 (xx)

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MX9306311A (es) * 1992-10-13 1994-04-29 Smithkline Beecham Plc Compuestos antagonistas del receptor de 5-ht4, procedimiento para su preparacion y composiciones farmaceuticas que los contienen
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JPH0820586A (ja) * 1994-07-05 1996-01-23 Sanwa Kagaku Kenkyusho Co Ltd 1−アザビシクロ[3.3.0]オクタン誘導体、その塩及び製法並びに用途
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JPH0873463A (ja) 1994-07-05 1996-03-19 Sanwa Kagaku Kenkyusho Co Ltd ベンゾピランカルボキサミド誘導体、その塩及び製法並びに用途
CN1068881C (zh) * 1994-09-27 2001-07-25 詹森药业有限公司 苯基-氧代-烷基-(4-哌啶基)苯甲酸酯衍生物
PL182502B1 (pl) * 1994-09-27 2002-01-31 Janssen Pharmaceutica Nv Nowe związki, pochodne bicyklicznego benzoesanu N-podstawionego piperydynylu, środek farmaceutyczny i sposób wytwarzania pochodnych bicyklicznego benzoesanu N-podstawionego piperydynylu
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TW402591B (en) 1997-07-11 2000-08-21 Janssen Pharmaceutica Nv Monocyclic benzamides of 3- or 4-substituted 4-(aminomethyl)-piperidine derivatives
DE69922186T2 (de) * 1998-04-28 2005-05-04 Dainippon Pharmaceutical Co., Ltd. 1-(1-subst.-4-piperidinyl)methyl]-4-piperidin-derivate, verafhren zu deren herstellung, pharmazeutische mixturen und intermediate zu deren herstellung
KR20010043618A (ko) * 1998-05-14 2001-05-25 사바 키스 ; 아틸라 만디 야노스 템페 ; 기울라 시미그 벤조푸란 유도체, 이를 포함하는 약제 조성물과 활성성분으로서 벤조푸란 유도체의 제조방법
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AU770580B2 (en) * 1998-11-23 2004-02-26 Janssen Pharmaceutica N.V. Use of prucalopride for the manufacture of a medicament for the treatment of dyspepsia
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SE9902987D0 (sv) 1999-08-24 1999-08-24 Astra Pharma Prod Novel compounds
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GB0107228D0 (en) 2001-03-22 2001-05-16 Astrazeneca Ab Chemical compounds
SE0103818D0 (sv) 2001-11-15 2001-11-15 Astrazeneca Ab Chemical compounds
EP1467991B1 (en) 2002-01-16 2005-05-18 Janssen Pharmaceutica N.V. Prucalopride-n-oxide
DE60330847D1 (de) * 2002-03-28 2010-02-25 Mitsubishi Tanabe Pharma Corp Benzofuranderivat
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SE0301369D0 (sv) 2003-05-09 2003-05-09 Astrazeneca Ab Chemical compounds
DE10349113A1 (de) * 2003-10-17 2005-05-12 Boehringer Ingelheim Pharma Verfahren zur Herstellung von Aminocrotonylverbindungen
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GB0525661D0 (en) * 2005-12-16 2006-01-25 Glaxo Group Ltd Novel compounds
EP3091011B1 (en) * 2006-04-07 2017-12-27 Vertex Pharmaceuticals Incorporated Modulators of atp-binding cassette transporters
CN102477002B (zh) * 2010-11-26 2015-04-15 苏州凯达生物医药技术有限公司 3-氨基-2,2-双甲基丙酰胺的制备方法
US9850227B2 (en) 2011-02-25 2017-12-26 Yuhan Corporation Diaminopyrimidine derivatives and processes for the preparation thereof
GB201103397D0 (xx) 2011-02-28 2011-04-13 Shire Movetis N V
KR101256908B1 (ko) * 2011-04-28 2013-04-23 (주)에이치비메디컬스 주름제거용 충전체
CN102295594B (zh) * 2011-07-12 2016-01-20 上海医药工业研究院 4-n-取代-1-(3-甲氧基丙基)-4-哌啶胺类化合物及制备和应用
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CN110963999B (zh) * 2019-11-27 2021-05-11 广东东阳光药业有限公司 2,3-二氢苯并呋喃酰胺衍生物及其用途
BR112022022184A2 (pt) * 2020-05-04 2023-01-17 Takeda Pharmaceuticals Co Derivados de n-(piperidin-4-il)benzamida agindo luminalmente

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Also Published As

Publication number Publication date
HU211350A9 (en) 1995-11-28
LTIP846A (en) 1995-02-27
HRP930483A2 (en) 1995-12-31
JPH04211685A (ja) 1992-08-03
GR3033461T3 (en) 2000-09-29
HUT60733A (en) 1992-10-28
RU2070884C1 (ru) 1996-12-27
HK1010727A1 (en) 1999-06-25
FI911096A0 (fi) 1991-03-05
LV10085B (en) 1995-02-20
DE69132119T2 (de) 2000-12-21
IL97018A (en) 1995-11-27
NZ237189A (en) 1992-11-25
PL169238B1 (pl) 1996-06-28
PL289323A1 (en) 1992-03-09
TNSN91010A1 (fr) 1992-10-25
AU636012B2 (en) 1993-04-08
FI101622B (fi) 1998-07-31
CS46091A3 (en) 1991-10-15
CY2235B1 (en) 2003-07-04
CA2037575A1 (en) 1991-09-07
SK282406B6 (sk) 2002-01-07
SI9110396A (en) 1997-12-31
IE910710A1 (en) 1991-09-11
MY108831A (en) 1996-11-30
IL97018A0 (en) 1992-03-29
PL168384B1 (en) 1996-02-29
LT3708B (en) 1996-02-26
UA25969A1 (uk) 1999-02-26
CZ286617B6 (cs) 2000-05-17
NO910863D0 (no) 1991-03-05
HU221627B1 (hu) 2002-12-28
EP0445862B1 (en) 2000-04-19
HRP930483B1 (en) 2001-04-30
FI911096A7 (fi) 1991-09-07
NO910863L (no) 1991-09-09
BG93979A (bg) 1993-12-24
ES2147175T3 (es) 2000-09-01
LV10085A (lv) 1994-05-10
PT96937B (pt) 1998-07-31
SI9110396B (sl) 2000-06-30
FI101622B1 (fi) 1998-07-31
CN1038936C (zh) 1998-07-01
EP0445862A3 (en) 1992-05-20
ATE191912T1 (de) 2000-05-15
BG60381B1 (bg) 1995-01-31
PL168356B1 (pl) 1996-02-29
ZA911611B (en) 1992-11-25
PL168686B1 (pl) 1996-03-29
PT96937A (pt) 1991-10-31
PL168811B1 (pl) 1996-04-30
NO177424C (no) 1995-09-13
DE69132119D1 (de) 2000-05-25
AU7207991A (en) 1991-09-12
GB9005014D0 (en) 1990-05-02
YU48854B (sh) 2002-06-19
CA2037575C (en) 2003-09-16
CN1054598A (zh) 1991-09-18
SK282407B6 (sk) 2002-01-07
SG47482A1 (en) 1998-04-17
US5262418A (en) 1993-11-16
JP2601566B2 (ja) 1997-04-16
YU39691A (sh) 1994-06-10
EP0445862A2 (en) 1991-09-11
HU910706D0 (en) 1991-09-30
KR0177521B1 (ko) 1999-03-20
DK0445862T3 (da) 2000-09-04
KR910016744A (ko) 1991-11-05
MA22076A1 (fr) 1991-10-01
NO177424B (no) 1995-06-06
PL168693B1 (pl) 1996-03-29
US5185335A (en) 1993-02-09

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