ZA9811925B - Thiazole derivatives. - Google Patents

Thiazole derivatives.

Info

Publication number: ZA9811925B
Authority: ZA; South Africa
Prior art keywords: thiazole derivatives; thiazole; derivatives
Prior art date: 1998-01-02

Application number

ZA9811925A

Other languages

English (en)

Inventor

Leo Alig

Kurt Hilpert

Albrecht Edenhofer

Thomas Weller

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-01-02

Filing date

1998-12-29

Publication date

2000-06-29

1998-12-29 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2000-06-29 Publication of ZA9811925B publication Critical patent/ZA9811925B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Physical Education & Sports Medicine (AREA)
Oncology (AREA)
Rheumatology (AREA)
Communicable Diseases (AREA)
Orthopedic Medicine & Surgery (AREA)
Urology & Nephrology (AREA)
Molecular Biology (AREA)
Dermatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Immunology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Virology (AREA)
Ophthalmology & Optometry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

ZA9811925A 1998-01-02 1998-12-29 Thiazole derivatives. ZA9811925B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP98100006		1998-01-02

Publications (1)

Publication Number	Publication Date
ZA9811925B true ZA9811925B (en)	2000-06-29

Family

ID=8231229

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA9811925A ZA9811925B (en)	1998-01-02	1998-12-29	Thiazole derivatives.

Country Status (29)

Country	Link
US (3)	US6100282A (es)
JP (1)	JP3113237B2 (es)
KR (1)	KR100312901B1 (es)
CN (1)	CN1080720C (es)
AR (1)	AR014949A1 (es)
AT (1)	ATE233746T1 (es)
AU (1)	AU720618B2 (es)
BR (1)	BR9900006A (es)
CA (1)	CA2257328C (es)
CO (1)	CO4990934A1 (es)
DE (1)	DE69811844T2 (es)
DK (1)	DK0928790T3 (es)
ES (1)	ES2193471T3 (es)
HR (1)	HRP980645A2 (es)
HU (1)	HUP9803040A3 (es)
ID (1)	ID21936A (es)
IL (1)	IL127785A (es)
MA (1)	MA26591A1 (es)
NO (1)	NO312067B1 (es)
NZ (2)	NZ333590A (es)
PE (1)	PE20000061A1 (es)
PL (1)	PL330619A1 (es)
PT (1)	PT928790E (es)
RU (1)	RU2218337C2 (es)
SG (1)	SG74686A1 (es)
TR (1)	TR199802765A2 (es)
UY (1)	UY25334A1 (es)
YU (1)	YU61398A (es)
ZA (1)	ZA9811925B (es)

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US6911462B2 (en) *	1998-05-22	2005-06-28	Avanir Pharmaceuticals	Benzimidazole compounds for regulating IgE
US6919366B2 (en) *	1998-05-22	2005-07-19	Avanir Pharmaceuticals	Benzimidazole derivatives as modulators of IgE
JP3530137B2 (ja)	1998-10-22	2004-05-24	エフ．ホフマン−ラロシュアーゲー	チアゾール誘導体
GB9826174D0 (en) *	1998-11-30	1999-01-20	Celltech Therapeutics Ltd	Chemical compounds
AU5826100A (en)	1999-07-13	2001-01-30	F. Hoffmann-La Roche Ag	Benzazepinones and quinazolines
US6759425B2 (en) *	1999-10-21	2004-07-06	Avanir Pharmaceuticals	Benzimidazole compounds for modulating IgE and inhibiting cellular proliferation
ES2287096T3 (es) *	2000-01-19	2007-12-16	Synvista Therapeutics, Inc.	Compuestos de tiazol, imidazol y oxazol y tratamientos de trastornos asociados con el envejecimiento de las proteinas.
JP2004528304A (ja) *	2001-03-12	2004-09-16	アバニール・ファーマシューティカルズ	ＩｇＥを調節し、細胞増殖を阻害するためのベンゾイミダゾール化合物
TWI314928B (en) *	2002-02-28	2009-09-21	Novartis A	5-phenylthiazole derivatives and use as pi3 kinase inhibitors
TW200304820A (en) *	2002-03-25	2003-10-16	Avanir Pharmaceuticals	Use of benzimidazole analogs in the treatment of cell proliferation
AU2003270426A1 (en)	2002-09-12	2004-04-30	Avanir Pharmaceuticals	PHENYL-INDOLE COMPOUNDS FOR MODULATING IgE AND INHIBITING CELLULAR PROLIFERATION
TWI276631B (en) *	2002-09-12	2007-03-21	Avanir Pharmaceuticals	Phenyl-aza-benzimidazole compounds for modulating IgE and inhibiting cellular proliferation
CN100491361C (zh) *	2003-01-27	2009-05-27	安斯泰来制药有限公司	噻唑衍生物及其作为vap-1抑制剂的用途
US20050256179A1 (en) *	2003-08-08	2005-11-17	Sircar Jagadish C	Selective pharmacologic inhibition of protein trafficking and related methods of treating human diseases
US7652146B2 (en) *	2004-02-06	2010-01-26	Bristol-Myers Squibb Company	Process for preparing 2-aminothiazole-5-carboxamides useful as kinase inhibitors
CA2580725A1 (en) *	2004-09-20	2006-03-30	4Sc Ag	Novel heterocyclic nf-kb inhibitors
EP1841431A4 (en) *	2005-01-26	2009-12-09	Irm Llc	COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS
US8716320B2 (en) *	2006-07-21	2014-05-06	Replidyne, Inc.	Antibacteriall heterocyclic ureas
JP5412429B2 (ja)	2007-07-23	2014-02-12	クレストーン・インコーポレーテッド	抗細菌性アミド及びスルホンアミド置換複素環式尿素化合物
WO2009015193A1 (en) *	2007-07-23	2009-01-29	Replidyne, Inc.	Antibacterial sulfone and sulfoxide substituted heterocyclic urea compounds
AR075899A1 (es) *	2009-03-20	2011-05-04	Onyx Therapeutics Inc	Tripeptidos epoxicetonas cristalinos inhibidores de proteasa
CN102936257B (zh) *	2012-08-30	2016-03-30	齐鲁工业大学	一类含银的噻唑西弗碱配合物的结构、制备和用途
US20200123147A1 (en)	2017-06-29	2020-04-23	Bayer Aktiengesellschaft	Thiazole compounds useful as prmt5 inhibitors
GB202012969D0 (en) *	2020-08-19	2020-09-30	Univ Of Oxford	Inhibitor compounds

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GB2009155B (en) *	1977-11-07	1982-07-21	Leo Pharm Prod Ltd	Chemical compounds
FR2581063B1 (fr) *	1985-04-30	1987-07-17	Chauvin Blache Lab	Amino-2 thiazoles n-substitues, leur procede de preparation et leur application en therapeutique
JPS62123180A (ja) *	1985-11-21	1987-06-04	Otsuka Pharmaceut Factory Inc	ｐ−アミノフエノ−ル誘導体
US5000775A (en) *	1985-12-31	1991-03-19	Monsanto Company	2-amino-4,5-disubstituted-oxazole/thiazole compounds as herbicide antidotes
JPS6348873A (ja) *	1986-08-19	1988-03-01	Toshiba Corp	ガスレ−ザ発振装置
CA2037153A1 (en) *	1990-03-09	1991-09-10	Leo Alig	Acetic acid derivatives
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FI922867A7 (fi) *	1991-06-21	1992-12-22	Tanabe Seiyaku Co	Dikarbonsyraderivat och foerfarande foer framstaellning av dem
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GB9125970D0 (en) *	1991-12-06	1992-02-05	Fujisawa Pharmaceutical Co	New compounds
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JPH0867676A (ja) *	1994-03-30	1996-03-12	Eisai Kagaku Kk	保護アミノチアゾリル酢酸誘導体
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JPH08337579A (ja) *	1995-06-14	1996-12-24	Fujisawa Pharmaceut Co Ltd	グアニジノチアゾ−ルおよびその抗潰瘍剤、ｈ２−受容体拮抗剤および抗菌剤としての用途
JPH09295974A (ja) *	1995-09-11	1997-11-18	Nippon Nohyaku Co Ltd	アゾール誘導体、その用途及びその製造方法並びにその使用方法
NZ299242A (en) *	1995-09-11	1997-12-19	Nihon Nohyaku Co Ltd	N-phenyl-n'-(phenyl substituted imidazol-5-yl, -oxazol-4-yl, and -thiazol-4-yl)urea derivatives
DE69624728T2 (de) *	1995-12-29	2003-07-10	Boehringer Ingelheim (Canada) Ltd., Laval	Phenyl thiazol derivate mit antiherpesvirus eigenschaften
EP0859002B1 (en) *	1997-02-13	2003-07-02	Tokuyama Corporation	Process for producing chloroacetylaminothiazoleacetic acid derivatives
MA26487A1 (fr) *	1997-04-29	2004-12-20	Smithkline Beecham Corp	Heterocyclecetohydrazides inhibiteurs de proteases, procede pour leur preparation et compositions pharmaceutiques les contenant .
JP6348873B2 (ja)	2015-04-24	2018-06-27	株式会社ソフイア	遊技機

1998
- 1998-12-22 US US09/218,567 patent/US6100282A/en not_active Expired - Fee Related
- 1998-12-24 PT PT98124670T patent/PT928790E/pt unknown
- 1998-12-24 AT AT98124670T patent/ATE233746T1/de not_active IP Right Cessation
- 1998-12-24 DE DE69811844T patent/DE69811844T2/de not_active Expired - Fee Related
- 1998-12-24 NZ NZ333590A patent/NZ333590A/xx unknown
- 1998-12-24 NZ NZ333591A patent/NZ333591A/xx unknown
- 1998-12-24 DK DK98124670T patent/DK0928790T3/da active
- 1998-12-24 ES ES98124670T patent/ES2193471T3/es not_active Expired - Lifetime
- 1998-12-28 NO NO19986159A patent/NO312067B1/no unknown
- 1998-12-29 PE PE1998001293A patent/PE20000061A1/es not_active Application Discontinuation
- 1998-12-29 AR ARP980106723A patent/AR014949A1/es not_active Application Discontinuation
- 1998-12-29 IL IL12778598A patent/IL127785A/en not_active IP Right Cessation
- 1998-12-29 ZA ZA9811925A patent/ZA9811925B/xx unknown
- 1998-12-29 HR HR98100006.0A patent/HRP980645A2/hr not_active Application Discontinuation
- 1998-12-30 CO CO98077476A patent/CO4990934A1/es unknown
- 1998-12-30 HU HU9803040A patent/HUP9803040A3/hu unknown
- 1998-12-30 CA CA002257328A patent/CA2257328C/en not_active Expired - Fee Related
- 1998-12-30 TR TR1998/02765A patent/TR199802765A2/xx unknown
- 1998-12-30 YU YU61398A patent/YU61398A/sh unknown
- 1998-12-30 AU AU96144/98A patent/AU720618B2/en not_active Ceased
- 1998-12-30 SG SG1998005978A patent/SG74686A1/en unknown
- 1998-12-30 MA MA25411A patent/MA26591A1/fr unknown
- 1998-12-30 PL PL98330619A patent/PL330619A1/xx not_active Application Discontinuation
- 1998-12-31 CN CN98125982A patent/CN1080720C/zh not_active Expired - Fee Related
- 1998-12-31 KR KR1019980063364A patent/KR100312901B1/ko not_active Expired - Fee Related
- 1998-12-31 UY UY25334A patent/UY25334A1/es not_active IP Right Cessation
1999
- 1999-01-04 JP JP11000010A patent/JP3113237B2/ja not_active Expired - Fee Related
- 1999-01-04 BR BR9900006-7A patent/BR9900006A/pt not_active Application Discontinuation
- 1999-01-04 ID IDP990001D patent/ID21936A/id unknown
- 1999-01-05 RU RU99100277/04A patent/RU2218337C2/ru not_active IP Right Cessation
2000
- 2000-03-15 US US09/526,033 patent/US6320054B1/en not_active Expired - Fee Related
2001
- 2001-06-11 US US09/878,704 patent/US6344562B1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
JP3113237B2 (ja)	2000-11-27
JP2000053664A (ja)	2000-02-22
MA26591A1 (fr)	2004-12-20
ES2193471T3 (es)	2003-11-01
PT928790E (pt)	2003-07-31
NZ333591A (en)	2000-05-26
DE69811844T2 (de)	2003-12-04
US6320054B1 (en)	2001-11-20
HK1020953A1 (en)	2000-05-26
DE69811844D1 (de)	2003-04-10
BR9900006A (pt)	2000-04-11
YU61398A (sh)	2001-12-26
CA2257328C (en)	2006-05-09
PE20000061A1 (es)	2000-02-09
AU9614498A (en)	1999-07-22
CN1224718A (zh)	1999-08-04
TR199802765A3 (tr)	1999-07-21
CA2257328A1 (en)	1999-07-02
US6100282A (en)	2000-08-08
DK0928790T3 (da)	2003-06-30
NO986159D0 (no)	1998-12-28
PL330619A1 (en)	1999-07-05
HU9803040D0 (en)	1999-02-01
NZ333590A (en)	2000-05-26
TR199802765A2 (xx)	1999-07-21
RU2218337C2 (ru)	2003-12-10
AR014949A1 (es)	2001-04-11
HUP9803040A2 (hu)	2000-04-28
ID21936A (id)	1999-08-12
HUP9803040A3 (en)	2001-04-28
US6344562B1 (en)	2002-02-05
ATE233746T1 (de)	2003-03-15
IL127785A0 (en)	1999-10-28
NO986159L (no)	1999-07-05
US20020010316A1 (en)	2002-01-24
CO4990934A1 (es)	2000-12-26
IL127785A (en)	2004-09-27
KR19990066925A (ko)	1999-08-16
KR100312901B1 (ko)	2002-01-15
SG74686A1 (en)	2000-08-22
UY25334A1 (es)	2001-01-31
CN1080720C (zh)	2002-03-13
AU720618B2 (en)	2000-06-08
NO312067B1 (no)	2002-03-11
HRP980645A2 (en)	1999-10-31

Publication	Publication Date	Title
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