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MA26591A1 - Nouveaux derives de thiazole - Google Patents

Nouveaux derives de thiazole

Info

Publication number
MA26591A1
MA26591A1 MA25411A MA25411A MA26591A1 MA 26591 A1 MA26591 A1 MA 26591A1 MA 25411 A MA25411 A MA 25411A MA 25411 A MA25411 A MA 25411A MA 26591 A1 MA26591 A1 MA 26591A1
Authority
MA
Morocco
Prior art keywords
thiazole derivatives
new thiazole
new
derivatives
thiazole
Prior art date
Application number
MA25411A
Other languages
English (en)
Inventor
Alig Leo
Hilpert Kurt
Weller Thomas
Edenhofer Albrecht
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MA26591A1 publication Critical patent/MA26591A1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/44Acylated amino or imino radicals
    • C07D277/48Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1024Tetrapeptides with the first amino acid being heterocyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Virology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
MA25411A 1998-01-02 1998-12-30 Nouveaux derives de thiazole MA26591A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98100006 1998-01-02

Publications (1)

Publication Number Publication Date
MA26591A1 true MA26591A1 (fr) 2004-12-20

Family

ID=8231229

Family Applications (1)

Application Number Title Priority Date Filing Date
MA25411A MA26591A1 (fr) 1998-01-02 1998-12-30 Nouveaux derives de thiazole

Country Status (29)

Country Link
US (3) US6100282A (fr)
JP (1) JP3113237B2 (fr)
KR (1) KR100312901B1 (fr)
CN (1) CN1080720C (fr)
AR (1) AR014949A1 (fr)
AT (1) ATE233746T1 (fr)
AU (1) AU720618B2 (fr)
BR (1) BR9900006A (fr)
CA (1) CA2257328C (fr)
CO (1) CO4990934A1 (fr)
DE (1) DE69811844T2 (fr)
DK (1) DK0928790T3 (fr)
ES (1) ES2193471T3 (fr)
HR (1) HRP980645A2 (fr)
HU (1) HUP9803040A3 (fr)
ID (1) ID21936A (fr)
IL (1) IL127785A (fr)
MA (1) MA26591A1 (fr)
NO (1) NO312067B1 (fr)
NZ (2) NZ333590A (fr)
PE (1) PE20000061A1 (fr)
PL (1) PL330619A1 (fr)
PT (1) PT928790E (fr)
RU (1) RU2218337C2 (fr)
SG (1) SG74686A1 (fr)
TR (1) TR199802765A2 (fr)
UY (1) UY25334A1 (fr)
YU (1) YU61398A (fr)
ZA (1) ZA9811925B (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6919366B2 (en) * 1998-05-22 2005-07-19 Avanir Pharmaceuticals Benzimidazole derivatives as modulators of IgE
US6911462B2 (en) * 1998-05-22 2005-06-28 Avanir Pharmaceuticals Benzimidazole compounds for regulating IgE
ES2221482T3 (es) 1998-10-22 2004-12-16 F. Hoffmann-La Roche Ag Derivados de tiazol.
GB9826174D0 (en) * 1998-11-30 1999-01-20 Celltech Therapeutics Ltd Chemical compounds
AU5826100A (en) 1999-07-13 2001-01-30 F. Hoffmann-La Roche Ag Benzazepinones and quinazolines
US6759425B2 (en) * 1999-10-21 2004-07-06 Avanir Pharmaceuticals Benzimidazole compounds for modulating IgE and inhibiting cellular proliferation
CN1426303A (zh) * 2000-01-19 2003-06-25 奥尔顿有限公司 噻唑、咪唑和噁唑化合物以及与蛋白老化相关疾病的治疗
ES2291455T3 (es) * 2001-03-12 2008-03-01 Avanir Pharmaceuticals Compuestos de bencimidazol para modular ige e inhibir la proliferacion celular.
AR038703A1 (es) * 2002-02-28 2005-01-26 Novartis Ag Derivados de 5-feniltiazol y uso como inhibidor de quinasa p i 3
TW200304820A (en) * 2002-03-25 2003-10-16 Avanir Pharmaceuticals Use of benzimidazole analogs in the treatment of cell proliferation
TWI276631B (en) * 2002-09-12 2007-03-21 Avanir Pharmaceuticals Phenyl-aza-benzimidazole compounds for modulating IgE and inhibiting cellular proliferation
AU2003270426A1 (en) 2002-09-12 2004-04-30 Avanir Pharmaceuticals PHENYL-INDOLE COMPOUNDS FOR MODULATING IgE AND INHIBITING CELLULAR PROLIFERATION
CN100491361C (zh) * 2003-01-27 2009-05-27 安斯泰来制药有限公司 噻唑衍生物及其作为vap-1抑制剂的用途
WO2005013950A2 (fr) * 2003-08-08 2005-02-17 Avanir Pharmaceuticals Inhibition pharmacologique selective du trafic proteique et methodes associees de traitement de maladies humaines
US7652146B2 (en) * 2004-02-06 2010-01-26 Bristol-Myers Squibb Company Process for preparing 2-aminothiazole-5-carboxamides useful as kinase inhibitors
BRPI0516958A (pt) * 2004-09-20 2008-03-25 4Sc Ag inibidores da nf-capab heterocìclicos
CA2593803A1 (fr) * 2005-01-26 2006-08-03 Irm Llc Composes et compositions utilises en tant qu'inhibiteurs de proteines kinases
WO2008011191A1 (fr) * 2006-07-21 2008-01-24 Replidyne, Inc. Urées hétérocycliques antibactériennes
WO2009015208A1 (fr) 2007-07-23 2009-01-29 Replidyne, Inc. Composés urée hétérocycliques substitués par amide et sulfonamide antibactériens
US8293919B2 (en) * 2007-07-23 2012-10-23 Crestone, Inc. Antibacterial sulfone and sulfoxide substituted heterocyclic urea compounds
AR075899A1 (es) * 2009-03-20 2011-05-04 Onyx Therapeutics Inc Tripeptidos epoxicetonas cristalinos inhibidores de proteasa
CN102936257B (zh) * 2012-08-30 2016-03-30 齐鲁工业大学 一类含银的噻唑西弗碱配合物的结构、制备和用途
EP3645531A1 (fr) 2017-06-29 2020-05-06 Bayer Aktiengesellschaft Composés thiazole utiles en tant qu'inhibiteurs de prmt5
GB202012969D0 (en) * 2020-08-19 2020-09-30 Univ Of Oxford Inhibitor compounds

Family Cites Families (20)

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GB2009155B (en) * 1977-11-07 1982-07-21 Leo Pharm Prod Ltd Chemical compounds
FR2581063B1 (fr) 1985-04-30 1987-07-17 Chauvin Blache Lab Amino-2 thiazoles n-substitues, leur procede de preparation et leur application en therapeutique
JPS62123180A (ja) * 1985-11-21 1987-06-04 Otsuka Pharmaceut Factory Inc p−アミノフエノ−ル誘導体
US5000775A (en) * 1985-12-31 1991-03-19 Monsanto Company 2-amino-4,5-disubstituted-oxazole/thiazole compounds as herbicide antidotes
JPS6348873A (ja) * 1986-08-19 1988-03-01 Toshiba Corp ガスレ−ザ発振装置
CA2037153A1 (fr) * 1990-03-09 1991-09-10 Leo Alig Derives de l'acide acetique
US5273982A (en) * 1990-03-09 1993-12-28 Hoffmann-La Roche Inc. Acetic acid derivatives
FI922867A7 (fi) * 1991-06-21 1992-12-22 Tanabe Seiyaku Co Dikarbonsyraderivat och foerfarande foer framstaellning av dem
US5294713A (en) * 1991-08-23 1994-03-15 Takeda Chemical Industries, Ltd. 2-piperazinone compounds and their use
GB9125970D0 (en) * 1991-12-06 1992-02-05 Fujisawa Pharmaceutical Co New compounds
US5514643A (en) * 1993-08-16 1996-05-07 Lucky Ltd. 2-aminothiazolecarboxamide derivatives, processes for preparing the same and use thereof for controlling phytopathogenic organisms
JPH0867676A (ja) * 1994-03-30 1996-03-12 Eisai Kagaku Kk 保護アミノチアゾリル酢酸誘導体
US6306840B1 (en) * 1995-01-23 2001-10-23 Biogen, Inc. Cell adhesion inhibitors
JPH08337579A (ja) * 1995-06-14 1996-12-24 Fujisawa Pharmaceut Co Ltd グアニジノチアゾ−ルおよびその抗潰瘍剤、h2−受容体拮抗剤および抗菌剤としての用途
NZ299242A (en) * 1995-09-11 1997-12-19 Nihon Nohyaku Co Ltd N-phenyl-n'-(phenyl substituted imidazol-5-yl, -oxazol-4-yl, and -thiazol-4-yl)urea derivatives
JPH09295974A (ja) * 1995-09-11 1997-11-18 Nippon Nohyaku Co Ltd アゾール誘導体、その用途及びその製造方法並びにその使用方法
KR19990076964A (ko) * 1995-12-29 1999-10-25 데이비드 이. 프랭크하우저 항헤르페스 바이러스 특성을 갖는 페닐 티아졸 유도체
DE69815906T2 (de) * 1997-02-13 2004-02-05 Tokuyama Corp., Tokuya Verfahren zur Herstellung von Chloroacetylaminothiazoleaceticsäure Derivate
MA26487A1 (fr) * 1997-04-29 2004-12-20 Smithkline Beecham Corp Heterocyclecetohydrazides inhibiteurs de proteases, procede pour leur preparation et compositions pharmaceutiques les contenant .
JP6348873B2 (ja) 2015-04-24 2018-06-27 株式会社ソフイア 遊技機

Also Published As

Publication number Publication date
KR19990066925A (ko) 1999-08-16
HRP980645A2 (en) 1999-10-31
NZ333590A (en) 2000-05-26
PL330619A1 (en) 1999-07-05
BR9900006A (pt) 2000-04-11
TR199802765A3 (tr) 1999-07-21
TR199802765A2 (xx) 1999-07-21
NO312067B1 (no) 2002-03-11
CA2257328C (fr) 2006-05-09
ZA9811925B (en) 2000-06-29
IL127785A0 (en) 1999-10-28
HU9803040D0 (en) 1999-02-01
IL127785A (en) 2004-09-27
CN1224718A (zh) 1999-08-04
AU720618B2 (en) 2000-06-08
CN1080720C (zh) 2002-03-13
US6100282A (en) 2000-08-08
US6320054B1 (en) 2001-11-20
US20020010316A1 (en) 2002-01-24
DE69811844D1 (de) 2003-04-10
NO986159D0 (no) 1998-12-28
UY25334A1 (es) 2001-01-31
ES2193471T3 (es) 2003-11-01
DK0928790T3 (da) 2003-06-30
AU9614498A (en) 1999-07-22
US6344562B1 (en) 2002-02-05
PE20000061A1 (es) 2000-02-09
ATE233746T1 (de) 2003-03-15
SG74686A1 (en) 2000-08-22
PT928790E (pt) 2003-07-31
JP3113237B2 (ja) 2000-11-27
NZ333591A (en) 2000-05-26
RU2218337C2 (ru) 2003-12-10
HK1020953A1 (en) 2000-05-26
DE69811844T2 (de) 2003-12-04
KR100312901B1 (ko) 2002-01-15
JP2000053664A (ja) 2000-02-22
HUP9803040A2 (hu) 2000-04-28
NO986159L (no) 1999-07-05
YU61398A (sh) 2001-12-26
CA2257328A1 (fr) 1999-07-02
ID21936A (id) 1999-08-12
AR014949A1 (es) 2001-04-11
HUP9803040A3 (en) 2001-04-28
CO4990934A1 (es) 2000-12-26

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