MA26487A1 - Heterocyclecetohydrazides inhibiteurs de proteases, procede pour leur preparation et compositions pharmaceutiques les contenant . - Google Patents
Heterocyclecetohydrazides inhibiteurs de proteases, procede pour leur preparation et compositions pharmaceutiques les contenant .Info
- Publication number
- MA26487A1 MA26487A1 MA25047A MA25047A MA26487A1 MA 26487 A1 MA26487 A1 MA 26487A1 MA 25047 A MA25047 A MA 25047A MA 25047 A MA25047 A MA 25047A MA 26487 A1 MA26487 A1 MA 26487A1
- Authority
- MA
- Morocco
- Prior art keywords
- heterocyclecetohydrazides
- preparation
- pharmaceutical compositions
- compositions containing
- protease inhibitor
- Prior art date
Links
- 229940124158 Protease/peptidase inhibitor Drugs 0.000 title 1
- 239000000137 peptide hydrolase inhibitor Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4506797P | 1997-04-29 | 1997-04-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA26487A1 true MA26487A1 (fr) | 2004-12-20 |
Family
ID=21935831
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA25047A MA26487A1 (fr) | 1997-04-29 | 1998-04-24 | Heterocyclecetohydrazides inhibiteurs de proteases, procede pour leur preparation et compositions pharmaceutiques les contenant . |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP1019046A4 (fr) |
| JP (1) | JP2002504097A (fr) |
| KR (1) | KR20010020391A (fr) |
| CN (1) | CN1261276A (fr) |
| AR (1) | AR012622A1 (fr) |
| AU (1) | AU7365198A (fr) |
| BR (1) | BR9809333A (fr) |
| CA (1) | CA2287989A1 (fr) |
| CO (1) | CO4940477A1 (fr) |
| HU (1) | HUP0001294A3 (fr) |
| IL (1) | IL132629A0 (fr) |
| MA (1) | MA26487A1 (fr) |
| NO (1) | NO995268L (fr) |
| PE (1) | PE69099A1 (fr) |
| PL (1) | PL337725A1 (fr) |
| TR (1) | TR199902703T2 (fr) |
| WO (1) | WO1998048799A1 (fr) |
| ZA (1) | ZA983522B (fr) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001526230A (ja) | 1997-12-19 | 2001-12-18 | スミスクライン・ビーチャム・コーポレイション | ヘテロアリール置換イミダゾール化合物、その医薬組成物および使用 |
| US6100282A (en) * | 1998-01-02 | 2000-08-08 | Hoffman-La Roche Inc. | Thiazole derivatives |
| MA26618A1 (fr) * | 1998-04-09 | 2004-12-20 | Smithkline Beecham Corp | Composes et compositions pharmaceutiques pour le traitement du paludisme |
| US6858617B2 (en) | 1998-05-26 | 2005-02-22 | Smithkline Beecham Corporation | Substituted imidazole compounds |
| ATE258055T1 (de) | 1998-11-04 | 2004-02-15 | Smithkline Beecham Corp | Pyridin-4-yl oder pyrimidin-4-yl substituierte pyrazine |
| CO5150165A1 (es) * | 1998-11-13 | 2002-04-29 | Smithkline Beecham Plc | Inhibidores de proteasa: tipo catepsina k |
| US20030144175A1 (en) | 1998-12-23 | 2003-07-31 | Smithkline Beecham Corporation | Protease inhibitors |
| US6596715B1 (en) | 1999-11-10 | 2003-07-22 | Smithkline Beecham Corporation | Protease inhibitors |
| AU1474801A (en) | 1999-11-10 | 2001-06-06 | Smithkline Beecham Corporation | Protease inhibitors |
| EP1232154A4 (fr) | 1999-11-10 | 2004-06-23 | Smithkline Beecham Corp | Inhibiteurs de protease |
| AU1783201A (en) | 1999-11-23 | 2001-06-04 | Smithkline Beecham Corporation | 3,4-dihydro-(1h)quinazolin-2-one compounds as csbp/p38 kinase inhibitors |
| EP1233950B1 (fr) | 1999-11-23 | 2005-10-05 | Smithkline Beecham Corporation | 3,4-dihydro-(1h)quinazolin-2-ones comme inhibiteurs de csbp/p38 kinase |
| EP1234821A4 (fr) * | 1999-12-03 | 2002-10-28 | Ono Pharmaceutical Co | Derives de 1.3.4-oxadiazoline et medicaments contenant ces derives utiles comme ingredients actifs |
| US6797720B2 (en) | 1999-12-03 | 2004-09-28 | Ono Pharmaceutical Co., Ltd. | 1,3,4-oxadiazoline derivative and an agent comprising its derivative as active ingredient |
| US7235551B2 (en) | 2000-03-02 | 2007-06-26 | Smithkline Beecham Corporation | 1,5-disubstituted-3,4-dihydro-1h-pyrimido[4,5-d]pyrimidin-2-one compounds and their use in treating csbp/p38 kinase mediated diseases |
| EA005893B1 (ru) | 2000-03-21 | 2005-06-30 | Смитклайн Бичам Корпорейшн | Ингибиторы протеаз |
| WO2003062192A1 (fr) | 2002-01-17 | 2003-07-31 | Smithkline Beecham Corporation | Derives de cetoamides a substitution cycloalkyle, utiles comme inhibiteurs de cathepsine k |
| WO2004007477A1 (fr) * | 2002-07-04 | 2004-01-22 | Aventis Pharma S.A. | Nouveaux derives acyl hydrazino du thiophene, leur procede de preparation, leur application a titre de medicaments, compositions pharmaceutiques et nouvelle utilisation |
| KR100962972B1 (ko) | 2002-07-26 | 2010-06-09 | 주식회사유한양행 | 1-페닐피페리딘-3-온 유도체 및 그의 제조방법 |
| WO2011015524A2 (fr) * | 2009-08-03 | 2011-02-10 | Bayer Cropscience Ag | Dérivés dhétérocycles fongicides |
| NZ704666A (en) * | 2012-08-23 | 2018-05-25 | Alios Biopharma Inc | Compounds for the treatment of paramoxyvirus viral infections |
| CN114716426A (zh) | 2013-08-21 | 2022-07-08 | 詹森生物制药有限公司 | 抗病毒化合物 |
| MA41614A (fr) | 2015-02-25 | 2018-01-02 | Alios Biopharma Inc | Composés antiviraux |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SK56798A3 (en) * | 1995-10-30 | 1998-12-02 | Smithkline Beecham Corp | Protease inhibitors, pharmaceutical composition containing them and their use |
-
1998
- 1998-04-24 MA MA25047A patent/MA26487A1/fr unknown
- 1998-04-27 PE PE1998000320A patent/PE69099A1/es not_active Application Discontinuation
- 1998-04-28 ZA ZA983522A patent/ZA983522B/xx unknown
- 1998-04-29 JP JP54738998A patent/JP2002504097A/ja active Pending
- 1998-04-29 CA CA002287989A patent/CA2287989A1/fr not_active Abandoned
- 1998-04-29 CN CN98806641A patent/CN1261276A/zh active Pending
- 1998-04-29 AU AU73651/98A patent/AU7365198A/en not_active Abandoned
- 1998-04-29 WO PCT/US1998/008740 patent/WO1998048799A1/fr not_active Ceased
- 1998-04-29 PL PL98337725A patent/PL337725A1/xx unknown
- 1998-04-29 HU HU0001294A patent/HUP0001294A3/hu unknown
- 1998-04-29 IL IL13262998A patent/IL132629A0/xx unknown
- 1998-04-29 KR KR1019997010013A patent/KR20010020391A/ko not_active Withdrawn
- 1998-04-29 CO CO98023491A patent/CO4940477A1/es unknown
- 1998-04-29 AR ARP980101999A patent/AR012622A1/es unknown
- 1998-04-29 EP EP98920926A patent/EP1019046A4/fr not_active Withdrawn
- 1998-04-29 TR TR1999/02703T patent/TR199902703T2/xx unknown
- 1998-04-29 BR BR9809333-9A patent/BR9809333A/pt not_active IP Right Cessation
-
1999
- 1999-10-28 NO NO995268A patent/NO995268L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CO4940477A1 (es) | 2000-07-24 |
| WO1998048799A1 (fr) | 1998-11-05 |
| CN1261276A (zh) | 2000-07-26 |
| PE69099A1 (es) | 1999-09-26 |
| TR199902703T2 (xx) | 2000-02-21 |
| EP1019046A4 (fr) | 2002-11-27 |
| ZA983522B (en) | 1998-10-29 |
| KR20010020391A (ko) | 2001-03-15 |
| AR012622A1 (es) | 2000-11-08 |
| NO995268D0 (no) | 1999-10-28 |
| IL132629A0 (en) | 2001-03-19 |
| NO995268L (no) | 1999-11-15 |
| JP2002504097A (ja) | 2002-02-05 |
| CA2287989A1 (fr) | 1998-11-05 |
| PL337725A1 (en) | 2000-08-28 |
| BR9809333A (pt) | 2000-07-04 |
| AU7365198A (en) | 1998-11-24 |
| HUP0001294A2 (hu) | 2001-04-28 |
| EP1019046A1 (fr) | 2000-07-19 |
| HUP0001294A3 (en) | 2001-06-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MA26494A1 (fr) | Inhibiteurs de proteases nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant. | |
| MA26487A1 (fr) | Heterocyclecetohydrazides inhibiteurs de proteases, procede pour leur preparation et compositions pharmaceutiques les contenant . | |
| MA26451A1 (fr) | Amides inhibiteurs de secretion de apo b/mtp, procede pour leur preparation et compositions pharmaceutiques les contenant. | |
| FR2748026B1 (fr) | Nouveaux inhibiteurs de metalloproteases, leur procede de preparation et les compositions pharmaceutiques qui les contiennent | |
| FR2780057B1 (fr) | Phenoxypropanolamines, procede pour leur preparation et compositions pharmaceutiques les contenant | |
| MA24529A1 (fr) | Pyrazolopyrimidinones nouvelles, procede pour leur preparation et compositions les contenant . | |
| MA26472A1 (fr) | Derives de n-hydroxy-b-sulfonylpropionamide, procede pour leur preparation et compositions pharmaceutiques les contenant. | |
| MA26499A1 (fr) | Derives de tetrazole, procede pour leur preparation et compositions pharmaceutiques les contenant . | |
| MA26630A1 (fr) | 4-phenylpyperidines nouvelles, procede pour leur preparation et compositions pharmaceutiques les contenant | |
| MA26743A1 (fr) | Composes nouveaux inhibiteurs de metalloproteases, procede pour leur preparation et compositions pharmaceutiques les contenant | |
| MA26687A1 (fr) | 4-carboxyamino-2-methyl-1,2,3,4-tetrahydroquinoleines, procede pour leur preparation et compositions pharmaceutiques les contenant | |
| MA26622A1 (fr) | Pyrazolopyrimidinones nouvelles, procede pour leur preparation et compositions pharmaceutiques les contenant | |
| MA26432A1 (fr) | Derives de 2-(2-oxo-ethylidene)-imidazolidine-4-one, procede pour leur preparation et compositions pharmaceutiques les contenant. | |
| MA26654A1 (fr) | Pyrrolopyrimidines nouvelles procede pour leur preparation et compositions pharmaceutiques les contenant | |
| MA26559A1 (fr) | Derives de d-proline, procede pour leur preparation, compositions pharmaceutiques les contenant et leur utilisation | |
| MA26516A1 (fr) | Tartrate d'un dipeptide substitue, procede pour sa preparation et compositions pharmaceutiques le contenant. | |
| DZ2890A1 (fr) | 4-Carboxamino-2-substitué-1,2,3,4-tétrahydroquinoléines, procédé pour leur préparation et compositions pharmaceutiques les contenant. | |
| MA26558A1 (fr) | Derives nouveaux de 6-0-methylerythromycine a, procede pour leur preparation et compositions pharmaceutiques les contenant. | |
| MA26492A1 (fr) | Inhibiteurs de proteases nouveaux et compositions pharmaceutiques les contenant . | |
| MA26614A1 (fr) | Bicyclo [2.2.1] heptanes nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant. | |
| MA26490A1 (fr) | Derives de tetrahydroisoquinoleine nouveaux, procedes pour leur preparation et compositions pharmaceutiques les contenant. | |
| MA26514A1 (fr) | Agonistes de prostaglandines, procede pour leur preparation et compositions pharmaceutiques les contenant. | |
| FR2751334B1 (fr) | Polysaccharides synthetiques, procede pour leur preparation et compositions pharmaceutiques les contenant | |
| MA26707A1 (fr) | Azalides nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant. | |
| DZ2894A1 (fr) | Compositions pharmaceutiques contenant des dérivésde pyridol Ä1,2-AÜpyrazine et procédé pour leur p réparation. |