ZA977326B - Tetrahydroquinoline derivatives - Google Patents

Tetrahydroquinoline derivatives

Info

Publication number: ZA977326B
Authority: ZA; South Africa
Prior art keywords: tetrahydroquinoline derivatives; tetrahydroquinoline; derivatives
Prior art date: 1996-08-17

Application number

ZA977326A

Other languages

English (en)

Inventor

Romano Di-Fabio

Alessandra Pasquarello

Fabio Maria Sabbatini

Original Assignee

Glaxo Wellcome Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-08-17

Filing date

1997-08-14

Publication date

1999-02-15

1997-08-14 Application filed by Glaxo Wellcome Spa filed Critical Glaxo Wellcome Spa

1999-02-15 Publication of ZA977326B publication Critical patent/ZA977326B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Quinoline Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

ZA977326A 1996-08-17 1997-08-14 Tetrahydroquinoline derivatives ZA977326B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB9617305.9A GB9617305D0 (en)	1996-08-17	1996-08-17	Heterocyclic compounds

Publications (1)

Publication Number	Publication Date
ZA977326B true ZA977326B (en)	1999-02-15

Family

ID=10798623

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA977326A ZA977326B (en)	1996-08-17	1997-08-14	Tetrahydroquinoline derivatives

Country Status (34)

Country	Link
US (1)	US6479488B1 (fr)
EP (1)	EP0922034B1 (fr)
JP (1)	JP4108129B2 (fr)
KR (1)	KR100552864B1 (fr)
CN (1)	CN1131214C (fr)
AP (1)	AP877A (fr)
AR (1)	AR008296A1 (fr)
AT (1)	ATE221052T1 (fr)
AU (1)	AU724473B2 (fr)
BR (1)	BR9711311B1 (fr)
CA (1)	CA2264118C (fr)
CO (1)	CO4900066A1 (fr)
CZ (1)	CZ296250B6 (fr)
DE (1)	DE69714265T2 (fr)
DK (1)	DK0922034T3 (fr)
EA (1)	EA001704B1 (fr)
ES (1)	ES2181030T3 (fr)
GB (1)	GB9617305D0 (fr)
HU (1)	HU225797B1 (fr)
ID (1)	ID18095A (fr)
IL (1)	IL128141A0 (fr)
IS (1)	IS4953A (fr)
MY (1)	MY116952A (fr)
NO (1)	NO312241B1 (fr)
NZ (1)	NZ333812A (fr)
PE (1)	PE107098A1 (fr)
PL (1)	PL194532B1 (fr)
PT (1)	PT922034E (fr)
SI (1)	SI0922034T1 (fr)
TR (1)	TR199900336T2 (fr)
TW (1)	TW449582B (fr)
WO (1)	WO1998007704A1 (fr)
YU (1)	YU6799A (fr)
ZA (1)	ZA977326B (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9706294D0 (en) *	1997-03-26	1997-05-14	Glaxo Wellcome Spa	Heterocyclic compound
MY125037A (en) *	1998-06-10	2006-07-31	Glaxo Wellcome Spa	1,2,3,4 tetrahydroquinoline derivatives
US6455734B1 (en)	2000-08-09	2002-09-24	Magnesium Diagnostics, Inc.	Antagonists of the magnesium binding defect as therapeutic agents and methods for treatment of abnormal physiological states
GB9929037D0 (en)	1999-12-08	2000-02-02	Glaxo Wellcome Spa	Heterocyclic derivatives
DE10132725A1 (de)	2001-07-05	2006-08-03	Grünenthal GmbH	Substituierte γ-Lactonverbindungen
IL162616A0 (en) *	2001-12-28	2005-11-20	Acadia Pharm Inc	Tetrahydroquinoline analogues as muscarinic agonists
US20050250767A1 (en) *	2003-01-23	2005-11-10	Weiner David M	Use of N-desmethylclozapine to treat human neuropsychiatric disease
US20050085463A1 (en) *	2003-01-23	2005-04-21	Weiner David M.	Use of N-desmethylclozapine to treat human neuropsychiatric disease
NZ541014A (en) *	2003-01-23	2008-05-30	Acadia Pharm Inc	Use of N-desmethylclozapine to treat schizophrenia while increasing the level of activity of a muscarinic receptor
WO2004073639A2 (fr) *	2003-02-19	2004-09-02	Merck & Co. Inc.	Traitement de la psychose avec un activateur ectopique du recepteur m1 muscarinique
MXPA06007244A (es) *	2003-12-22	2006-08-18	Acadia Pharm Inc	Analogos amino sustituidos de diaril[a,d]ciclohepteno como agonistas muscarinicos y metodos de tratamiento de trastornos neuropsiquiatricos.
RU2006138497A (ru) *	2004-04-01	2008-05-10	Акадиа Фармасьютикалз Инк. (Us)	Кристаллические формы n-десметилклозапина
EP1908753B1 (fr)	2005-07-22	2014-12-17	Mochida Pharmaceutical Co., Ltd.	Nouveau dérivé d'acétamide d'hétérocyclidène
RU2451014C2 (ru) *	2005-07-22	2012-05-20	Мотида Фармасьютикал Ко., Лтд.	Новое производное гетероциклиден ацетамида
US8480797B2 (en)	2005-09-12	2013-07-09	Abela Pharmaceuticals, Inc.	Activated carbon systems for facilitating use of dimethyl sulfoxide (DMSO) by removal of same, related compounds, or associated odors
EP2324838A1 (fr) *	2005-09-12	2011-05-25	Abela Pharmaceuticals, Inc.	Compositions comprenant du diméthylsulfoxyde
US8435224B2 (en)	2005-09-12	2013-05-07	Abela Pharmaceuticals, Inc.	Materials for facilitating administration of dimethyl sulfoxide (DMSO) and related compounds
US7955418B2 (en)	2005-09-12	2011-06-07	Abela Pharmaceuticals, Inc.	Systems for removing dimethyl sulfoxide (DMSO) or related compounds or odors associated with same
US20070105836A1 (en) *	2005-10-31	2007-05-10	Lars Pettersson	Prodrugs of muscarinic agonists and methods of treatment of neuropsychiatric disorders
BRPI0921494A2 (pt)	2008-11-03	2018-10-30	Prad Reasearch And Development Ltd	método de planejamento de uma operação de amostragem para uma formação subterrãnea, método de contolar uma operação de amostragem de formação subterrânea, método de controlar uma operação de perfuração para uma formação subterrãnea, e método de realizar uma amostragem durante a operação de perfuração.
KR20120093993A (ko)	2009-10-30	2012-08-23	아벨라 파마슈티칼스, 인코포레이티드	퇴행성 관절염 치료를 위한 디메틸설폭사이드 및 메틸설포닐메탄 제제
CA2850707C (fr)	2011-10-03	2023-03-21	The University Of Utah Research Foundation	Application d'antagonistes du recepteur 5-ht6 dans l'attenuation des deficits cognitifs lies au syndrome de down

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0386839B1 (fr) *	1989-03-08	1997-01-15	Merck Sharp & Dohme Ltd.	Dérivés de tétrahydroquinoléine utiles pour les affections neurodégénératives
BR9610733A (pt)	1995-09-29	1999-07-13	Glaxo Wellcome Spa	Composto processos para a preparação do mesmo e para o tratamento de um mamífero composição farmacêutica e utilização de um composto

1996
- 1996-08-17 GB GBGB9617305.9A patent/GB9617305D0/en active Pending
1997
- 1997-08-14 KR KR1019997001280A patent/KR100552864B1/ko not_active Expired - Fee Related
- 1997-08-14 WO PCT/EP1997/004440 patent/WO1998007704A1/fr not_active Ceased
- 1997-08-14 US US09/147,568 patent/US6479488B1/en not_active Expired - Fee Related
- 1997-08-14 EP EP97943809A patent/EP0922034B1/fr not_active Expired - Lifetime
- 1997-08-14 YU YU6799A patent/YU6799A/sh unknown
- 1997-08-14 ZA ZA977326A patent/ZA977326B/xx unknown
- 1997-08-14 EA EA199900121A patent/EA001704B1/ru not_active IP Right Cessation
- 1997-08-14 AT AT97943809T patent/ATE221052T1/de not_active IP Right Cessation
- 1997-08-14 DE DE69714265T patent/DE69714265T2/de not_active Expired - Lifetime
- 1997-08-14 AU AU45518/97A patent/AU724473B2/en not_active Ceased
- 1997-08-14 MY MYPI97003742A patent/MY116952A/en unknown
- 1997-08-14 PE PE1997000718A patent/PE107098A1/es not_active Application Discontinuation
- 1997-08-14 BR BRPI9711311-5A patent/BR9711311B1/pt not_active IP Right Cessation
- 1997-08-14 CA CA002264118A patent/CA2264118C/fr not_active Expired - Fee Related
- 1997-08-14 PT PT97943809T patent/PT922034E/pt unknown
- 1997-08-14 ID IDP972834A patent/ID18095A/id unknown
- 1997-08-14 AP APAP/P/1999/001459A patent/AP877A/en active
- 1997-08-14 SI SI9730404T patent/SI0922034T1/xx unknown
- 1997-08-14 HU HU9903108A patent/HU225797B1/hu not_active IP Right Cessation
- 1997-08-14 JP JP51037298A patent/JP4108129B2/ja not_active Expired - Fee Related
- 1997-08-14 CZ CZ0052999A patent/CZ296250B6/cs not_active IP Right Cessation
- 1997-08-14 AR ARP970103703A patent/AR008296A1/es active IP Right Grant
- 1997-08-14 TR TR1999/00336T patent/TR199900336T2/xx unknown
- 1997-08-14 PL PL97331562A patent/PL194532B1/pl not_active IP Right Cessation
- 1997-08-14 IL IL12814197A patent/IL128141A0/xx not_active IP Right Cessation
- 1997-08-14 NZ NZ333812A patent/NZ333812A/xx active Application Revival
- 1997-08-14 CN CN97197233A patent/CN1131214C/zh not_active Expired - Fee Related
- 1997-08-14 ES ES97943809T patent/ES2181030T3/es not_active Expired - Lifetime
- 1997-08-14 DK DK97943809T patent/DK0922034T3/da active
- 1997-08-14 CO CO97046782A patent/CO4900066A1/es unknown
- 1997-08-30 TW TW086112442A patent/TW449582B/zh not_active IP Right Cessation
1999
- 1999-01-22 IS IS4953A patent/IS4953A/is unknown
- 1999-02-16 NO NO19990723A patent/NO312241B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
PT922034E (pt)	2002-12-31
NZ333812A (en)	2000-07-28
CA2264118A1 (fr)	1998-02-26
GB9617305D0 (en)	1996-09-25
PE107098A1 (es)	1999-01-15
EP0922034A1 (fr)	1999-06-16
TR199900336T2 (xx)	1999-04-21
IS4953A (is)	1999-01-22
EA199900121A1 (ru)	1999-10-28
DE69714265T2 (de)	2003-03-06
JP2001508031A (ja)	2001-06-19
PL331562A1 (en)	1999-07-19
EP0922034B1 (fr)	2002-07-24
AR008296A1 (es)	1999-12-29
HU225797B1 (en)	2007-09-28
CN1131214C (zh)	2003-12-17
DE69714265D1 (de)	2002-08-29
CA2264118C (fr)	2008-06-17
ES2181030T3 (es)	2003-02-16
HUP9903108A3 (en)	2004-04-28
BR9711311B1 (pt)	2009-01-13
CN1227544A (zh)	1999-09-01
WO1998007704A1 (fr)	1998-02-26
BR9711311A (pt)	1999-08-17
SI0922034T1 (en)	2003-02-28
NO990723D0 (no)	1999-02-16
AU4551897A (en)	1998-03-06
KR100552864B1 (ko)	2006-02-20
ID18095A (id)	1998-02-26
ATE221052T1 (de)	2002-08-15
MY116952A (en)	2004-04-30
IL128141A0 (en)	1999-11-30
CO4900066A1 (es)	2000-03-27
AP9901459A0 (en)	1999-03-31
NO990723L (no)	1999-04-14
CZ296250B6 (cs)	2006-02-15
PL194532B1 (pl)	2007-06-29
NO312241B1 (no)	2002-04-15
KR20000068172A (ko)	2000-11-25
AP877A (en)	2000-09-27
US6479488B1 (en)	2002-11-12
JP4108129B2 (ja)	2008-06-25
AU724473B2 (en)	2000-09-21
TW449582B (en)	2001-08-11
CZ52999A3 (cs)	1999-07-14
DK0922034T3 (da)	2002-11-18
EA001704B1 (ru)	2001-06-25
YU6799A (sh)	2000-03-21

Publication	Publication Date	Title
AP9500745A0 (en)	1995-07-31	Quinoline derivatives
IL125811A0 (en)	1999-04-11	6-phenylpyridyl-2-amine derivatives
AP9701156A0 (en)	1998-01-31	6-phenylpyridyl-2-amine derivatives
IL125379A (en)	2003-05-29	19-nor-pregnene derivatives
ZA977326B (en)	1999-02-15	Tetrahydroquinoline derivatives
HUP9902993A3 (en)	2002-01-28	Alkylaminobenzothiazole and -benzoxazole derivatives
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IL125149A0 (en)	1999-01-26	Pyrazol-4-yl-hetaroyl derivatives
ZA954269B (en)	1996-05-14	Quinoline derivatives
PL334558A1 (en)	2000-03-13	Cephalosporinic derivatives
HU9701479D0 (en)	1997-10-28	N-benzylazolium derivatives
GB9402275D0 (en)	1994-03-30	Quinoline derivatives
GB9413150D0 (en)	1994-08-24	Quinoline derivatives
ZA972051B (en)	1998-09-10	Benzodiazonine derivatives
GB9603226D0 (en)	1996-04-17	Heterocyclyl-ergoline derivatives
GB9600063D0 (en)	1996-03-06	Guaridine derivatives
ZA971911B (en)	1998-09-07	2-thioxo-tetrahydropyrimidin-4-one derivatives
IL130283A0 (en)	2000-06-01	Polysaccharide-peptide derivatives
GB9702049D0 (en)	1997-03-19	Tetrahhydroisoquinoline derivatives
HU9601036D0 (en)	1996-06-28	Aryl-sulfonyl-hydroxamic-acid derivatives
IL126806A0 (en)	1999-08-17	Quinoline derivatives
GB9413937D0 (en)	1994-08-31	Quinoline derivatives
GB9402306D0 (en)	1994-03-30	Quinoline derivatives