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ZA904827B - Indenoindole compounds ii - Google Patents

Indenoindole compounds ii

Info

Publication number
ZA904827B
ZA904827B ZA904827A ZA904827A ZA904827B ZA 904827 B ZA904827 B ZA 904827B ZA 904827 A ZA904827 A ZA 904827A ZA 904827 A ZA904827 A ZA 904827A ZA 904827 B ZA904827 B ZA 904827B
Authority
ZA
South Africa
Prior art keywords
lower alkyl
hydrogen
group
cor
alkyl group
Prior art date
Application number
ZA904827A
Other languages
English (en)
Inventor
Malcolm Sainsbury
Sainsbury Malcolm
Howard G Shertzer
G Shertzer Howard
Original Assignee
Univ Bath
Univ Cincinnati
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Bath, Univ Cincinnati filed Critical Univ Bath
Publication of ZA904827B publication Critical patent/ZA904827B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/94[b, c]- or [b, d]-condensed containing carbocyclic rings other than six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/58[b]- or [c]-condensed
    • C07D209/70[b]- or [c]-condensed containing carbocyclic rings other than six-membered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
ZA904827A 1989-06-22 1990-06-21 Indenoindole compounds ii ZA904827B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8902274A SE8902274D0 (sv) 1989-06-22 1989-06-22 Indenoidole compounds ii

Publications (1)

Publication Number Publication Date
ZA904827B true ZA904827B (en) 1991-04-24

Family

ID=20376370

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA904827A ZA904827B (en) 1989-06-22 1990-06-21 Indenoindole compounds ii

Country Status (34)

Country Link
EP (1) EP0409410B1 (is)
JP (1) JP3064411B2 (is)
KR (1) KR920702679A (is)
CN (1) CN1033029C (is)
AT (1) ATE135688T1 (is)
BG (1) BG60317B2 (is)
CA (1) CA2060897A1 (is)
DD (1) DD297960A5 (is)
DE (1) DE69025998T2 (is)
DK (1) DK0409410T3 (is)
DZ (1) DZ1428A1 (is)
ES (1) ES2084660T3 (is)
FI (1) FI100800B (is)
GR (1) GR3019779T3 (is)
HR (1) HRP920903B1 (is)
HU (1) HUT59097A (is)
IE (1) IE74682B1 (is)
IL (1) IL94830A (is)
IS (1) IS3590A7 (is)
LT (1) LT3675B (is)
LV (1) LV10253B (is)
MX (1) MX21244A (is)
MY (1) MY107311A (is)
NO (1) NO177932C (is)
NZ (1) NZ234175A (is)
PL (1) PL167761B1 (is)
PT (1) PT94468B (is)
RO (1) RO111573B1 (is)
RU (1) RU2104270C1 (is)
SE (1) SE8902274D0 (is)
SI (1) SI9011223B (is)
WO (1) WO1990015799A1 (is)
YU (1) YU122390A (is)
ZA (1) ZA904827B (is)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL99750A0 (en) * 1990-10-16 1992-08-18 Univ Bath Indenoindole compounds
JPH0656669A (ja) * 1992-06-11 1994-03-01 Asahi Breweries Ltd 活性酸素消去作用を持つプテリン誘導体製剤
SE9302431D0 (sv) * 1993-07-16 1993-07-16 Ab Astra Use of indenoindole compounds
AU675141B2 (en) * 1993-07-20 1997-01-23 Adir Et Compagnie (Thia)cycloalkyl(b)indoles, process for preparing them and pharmaceutical compositions containing them
JP2002531569A (ja) * 1998-12-04 2002-09-24 ワイス 新規なカリウムチャンネル開放物質としての置換ベンゾフラノインドール及びインデノインドール
US6288099B1 (en) 1998-12-04 2001-09-11 American Home Products Corporation Substituted benzofuranoindoles and indenoindoles as novel potassium channel openers
FR2826009B1 (fr) * 2001-06-13 2003-08-15 Servier Lab Nouveaux derives d'indenoindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
PT1910338E (pt) 2005-07-14 2010-12-02 Irm Llc Compostos heterotetracíclicos como miméticos de tpo
DE102006047231B4 (de) * 2006-10-04 2009-02-12 Hemmerling, Hans-Jörg, Dr. Substituierte Indeno[1,2-b]indolderivate als neue Hemmstoffe der Protein Kinase CK2 und ihre Verwendung als Tumor Therapeutika, Cytostatika und Diagnostika
EP3597184A3 (en) 2011-06-16 2020-04-22 Korea Research Institute of Chemical Technology Indanone derivatives, pharmaceutically acceptable salts or optical isomers thereof, preparation method for same, and pharmaceutical compositions containing same as active ingredient for preventing or treating viral diseases
EP4585266A3 (en) 2012-12-14 2025-09-17 Korea Research Institute of Chemical Technology Compound, pharmaceutically acceptable salt or optical isomer thereof, method for preparing same, and pharmaceutical composition for prevention or treatment of viral diseases containing same as active ingredient
TW202448874A (zh) 2020-04-20 2024-12-16 瑞士商諾華公司 抗病毒性1,3-二氧代茚化合物
TWI832045B (zh) 2020-04-20 2024-02-11 瑞士商諾華公司 抗病毒性1,3-二氧代茚化合物

Also Published As

Publication number Publication date
IL94830A (en) 1996-07-23
IE74682B1 (en) 1997-07-30
PL167761B1 (pl) 1995-10-31
IE902247L (en) 1990-12-22
LV10253A (lv) 1994-10-20
ES2084660T3 (es) 1996-05-16
RO111573B1 (ro) 1996-11-29
IS3590A7 (is) 1990-12-23
FI100800B (fi) 1998-02-27
EP0409410B1 (en) 1996-03-20
CA2060897A1 (en) 1990-12-23
NO177932B (no) 1995-09-11
LT3675B (en) 1996-01-25
NZ234175A (en) 1992-12-23
BG60317B2 (bg) 1994-07-25
HUT59097A (en) 1992-04-28
JPH04505923A (ja) 1992-10-15
MY107311A (en) 1995-11-30
KR920702679A (ko) 1992-10-06
HRP920903B1 (en) 1998-06-30
DZ1428A1 (fr) 2004-09-13
YU122390A (sh) 1992-09-07
SE8902274D0 (sv) 1989-06-22
WO1990015799A1 (en) 1990-12-27
AU644084B2 (en) 1993-12-02
IE902247A1 (en) 1991-01-16
PL285752A1 (en) 1991-03-11
ATE135688T1 (de) 1996-04-15
DD297960A5 (de) 1992-01-30
LV10253B (en) 1995-04-20
CN1033029C (zh) 1996-10-16
PT94468B (pt) 1997-12-31
RU2104270C1 (ru) 1998-02-10
SI9011223A (en) 1997-10-31
EP0409410A1 (en) 1991-01-23
JP3064411B2 (ja) 2000-07-12
DE69025998T2 (de) 1996-08-08
CN1051554A (zh) 1991-05-22
NO915049D0 (no) 1991-12-20
NO177932C (no) 1995-12-20
PT94468A (pt) 1991-02-08
AU5836990A (en) 1991-01-08
GR3019779T3 (en) 1996-07-31
HRP920903A2 (hr) 1994-04-30
HU904825D0 (en) 1992-03-30
LTIP912A (en) 1995-03-27
MX21244A (es) 1994-03-31
NO915049L (no) 1992-02-21
SI9011223B (sl) 1998-08-31
DK0409410T3 (da) 1996-04-29
DE69025998D1 (de) 1996-04-25
FI915999A0 (fi) 1991-12-19
IL94830A0 (en) 1991-04-15

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