[go: up one dir, main page]

ZA200810863B - Humanized anti-human osteopontin antibody - Google Patents

Humanized anti-human osteopontin antibody

Info

Publication number
ZA200810863B
ZA200810863B ZA200810863A ZA200810863A ZA200810863B ZA 200810863 B ZA200810863 B ZA 200810863B ZA 200810863 A ZA200810863 A ZA 200810863A ZA 200810863 A ZA200810863 A ZA 200810863A ZA 200810863 B ZA200810863 B ZA 200810863B
Authority
ZA
South Africa
Prior art keywords
human osteopontin
humanized anti
osteopontin antibody
antibody
human
Prior art date
Application number
ZA200810863A
Other languages
English (en)
Inventor
Nobuchika Yamamoto
Fumihiko Sakai
Hirofumi Higuchi
Masaharu Torikai
Toshihiro Nakashima
Original Assignee
Astellas Pharma Inc
Chemo Sero Therapeut Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astellas Pharma Inc, Chemo Sero Therapeut Res Inst filed Critical Astellas Pharma Inc
Publication of ZA200810863B publication Critical patent/ZA200810863B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Pulmonology (AREA)
  • Physics & Mathematics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Plant Pathology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ZA200810863A 2006-05-31 2008-12-23 Humanized anti-human osteopontin antibody ZA200810863B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2006152892 2006-05-31

Publications (1)

Publication Number Publication Date
ZA200810863B true ZA200810863B (en) 2010-08-25

Family

ID=38778682

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200810863A ZA200810863B (en) 2006-05-31 2008-12-23 Humanized anti-human osteopontin antibody

Country Status (17)

Country Link
US (1) US7807161B2 (zh)
EP (1) EP2025749B8 (zh)
JP (1) JP4064441B2 (zh)
KR (1) KR20090024748A (zh)
CN (1) CN101495632B (zh)
AT (1) ATE553130T1 (zh)
AU (1) AU2007268591A1 (zh)
BR (1) BRPI0711229A2 (zh)
CA (1) CA2653661A1 (zh)
ES (1) ES2384350T3 (zh)
IL (1) IL195503A0 (zh)
MX (1) MX2008015309A (zh)
NO (1) NO20085282L (zh)
RU (1) RU2429016C2 (zh)
TW (1) TW200813087A (zh)
WO (1) WO2007139164A1 (zh)
ZA (1) ZA200810863B (zh)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2243829T3 (pl) 2008-01-11 2015-04-30 Astellas Pharma Inc Polepszone humanizowane przeciwciało anty-ludzka integryna alfa9,
JP5339748B2 (ja) * 2008-03-11 2013-11-13 国立大学法人北海道大学 ヒトオステオポンチンの活性化を阻害する物質をスクリーニングする方法
CA2721716C (en) * 2008-04-24 2019-09-24 Gene Techno Science Co., Ltd. Humanized antibodies specific for amino acid sequence rgd of an extracellular matrix protein and the uses thereof
US8658770B2 (en) 2009-10-21 2014-02-25 Hiroshima University Integrin alpha 8-beta 1-specific monoclonal antibody
WO2012050646A2 (en) 2010-06-29 2012-04-19 The Trustees Of The University Of Pennsylvania Biomimetic chemical sensors using nanoelectronic readout of olfactory receptors
WO2013033359A1 (en) * 2011-08-31 2013-03-07 The Trustees Of The University Of Pennsylvania Carbon nanotube biosensors and related methods
US20150259402A1 (en) 2012-10-19 2015-09-17 Evec Inc. Human antibody specific to toxin produced from clostridium difficile, or antigen-binding fragment thereof
US9649375B2 (en) 2013-03-14 2017-05-16 The Administrators Of The Tulane Educational Fund Immunogenic peptide conjugate and method for inducing an anti-influenza therapeutic antibody response therewith
CN104250302B (zh) 2013-06-26 2017-11-14 上海君实生物医药科技股份有限公司 抗pd‑1抗体及其应用
TW201623329A (zh) * 2014-06-30 2016-07-01 亞佛瑞司股份有限公司 針對骨調素截斷變異體的疫苗及單株抗體暨其用途
US11415546B2 (en) 2014-09-05 2022-08-16 The Trustees Of The University Of Pennsylvania Volatile organic compound-based diagnostic systems and methods
WO2018009440A1 (en) 2016-07-06 2018-01-11 Dana Automotive Systems Group, Llc Axle and propeller shaft quick-connect joint attachment assembly
KR20180000875U (ko) 2016-09-21 2018-03-29 전은희 조명 모듈
EP3824906A1 (en) 2016-12-21 2021-05-26 Amgen Inc. Anti-tnf alpha antibody formulations
CN112480250B (zh) * 2020-12-23 2022-03-15 上海交通大学 一种抗人骨桥蛋白的抗体及其应用
US20230272058A1 (en) * 2021-07-02 2023-08-31 Washington University Compositions and methods for preventing acute kidney injury-induced acute lung injury (aki-ali)

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
IL162181A (en) 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
US5859205A (en) * 1989-12-21 1999-01-12 Celltech Limited Humanised antibodies
WO1994020632A1 (fr) 1993-03-11 1994-09-15 Juridical Foundation The Chemo-Sero-Therapeutic R Esearch Insitute Anticorps monoclonal dirige contre le vih
DE4425115A1 (de) 1994-07-15 1996-01-18 Boehringer Mannheim Gmbh Verfahren zur Modifizierung der Stabilität von Antikörpern
DE69726003T2 (de) * 1996-07-16 2004-08-26 Andreas Plückthun Immunglobulin-superfamilie domainen und fragmente mit erhöhter löslichkeit
ES2314040T3 (es) 2001-04-05 2009-03-16 Immuno-Biological Laboratories Co., Ltd. Anticuerpo anti-osteopontina y su uso.
CA2453662A1 (en) * 2001-07-19 2003-01-30 Stefan Ewert Modification of human variable domains
AU2002332290B2 (en) * 2001-09-25 2007-11-08 Astellas Pharma Inc. Recombinant anti-osteopontin antibody and use thereof
WO2006043954A1 (en) 2004-10-13 2006-04-27 Genentech, Inc. Method for treating tumors using anti-osteopontin antibodies
CA2487321A1 (en) * 2002-06-17 2003-12-24 The Government Of The United States Of America, As Represented By The Se Cretary Of The Department Of Health And Human Services Specificity grafting of a murine antibody onto a human framework
JPWO2004103403A1 (ja) * 2003-05-23 2006-07-20 株式会社 免疫生物研究所 免疫担当細胞活性化阻害剤およびその用途
JP2006152892A (ja) 2004-11-29 2006-06-15 Anest Iwata Corp 気体吸排機械
KR101262058B1 (ko) * 2005-02-08 2013-05-08 잇빤 자이단호진 가가쿠오요비겟세이료호겐쿠쇼 항체를 개선하기 위한 방법

Also Published As

Publication number Publication date
US20090053212A1 (en) 2009-02-26
EP2025749B1 (en) 2012-04-11
EP2025749A4 (en) 2009-12-16
JP2008005836A (ja) 2008-01-17
ES2384350T3 (es) 2012-07-04
IL195503A0 (en) 2011-08-01
KR20090024748A (ko) 2009-03-09
TW200813087A (en) 2008-03-16
US7807161B2 (en) 2010-10-05
RU2008152769A (ru) 2010-07-20
CN101495632A (zh) 2009-07-29
NO20085282L (no) 2009-02-26
EP2025749B8 (en) 2012-05-23
JP4064441B2 (ja) 2008-03-19
CN101495632B (zh) 2011-08-03
RU2429016C2 (ru) 2011-09-20
AU2007268591A1 (en) 2007-12-06
EP2025749A1 (en) 2009-02-18
ATE553130T1 (de) 2012-04-15
MX2008015309A (es) 2009-03-02
WO2007139164A1 (ja) 2007-12-06
BRPI0711229A2 (pt) 2013-01-08
CA2653661A1 (en) 2007-12-06

Similar Documents

Publication Publication Date Title
ZA200810863B (en) Humanized anti-human osteopontin antibody
WO2005092926A3 (en) Reducing the risk of human and anti-human antibodies through v gene manipulation
ATE535545T1 (de) Chimäre und humanisierte monoklonale antikörper gegen interleukin-13
NL1027975A1 (nl) Antilichamen tegen MAdCAM.
HRP20181218T1 (hr) Humanizirana anti-il-6 protutijela, pripravci, postupci pripreme i upotrebe
WO2007129895A3 (en) Deimmunized antagonistic anti-human cd40 monoclonal antibody from the ch5d12 antibody
ATE520716T1 (de) Humanisierter anti-cd4-antikörper mit immunsuppressiven eigenschaften
WO2008070344A3 (en) Compositions and methods for binding sphingosine-1-phosphate
NZ585622A (en) Hepatitis c virus antibodies
ATE512986T1 (de) Antikörper gegen clostridium difficile-toxine und ihre verwendung
WO2006084264A3 (en) Cd20 antibody variants and uses thereof
EA200702008A1 (ru) Антитела-нейтрализаторы гранулоцитарно-макрофагального колониестимулирующего фактора человека
EP1836294A4 (en) ANTI-IL-12 ANTIBODIES, EPITOPES, COMPOSITIONS, METHODS AND USES
WO2004108766A3 (en) Anti-hgf-r antibodies and their use
WO2007087289A3 (en) Anti-fcrn antibodies for treatement of auto/allo immune conditions
WO2006061723A3 (en) Human monoclonal antibodies to influenza m2 protein and methods of making and using same
WO2009135861A3 (en) Humanized antibodies against human interferon-alpha
MX2009005103A (es) Conjugado anti-idiotipo y su uso como un estandar en un inmunoensayo.
WO2011112850A3 (en) Humanized and chimeric anti-properdin antibodies
WO2008094942A8 (en) Humanized antibodies against cxcr3
MX2008002161A (es) Anticuerpos quimericos con regiones de primate del nuevo mundo.
DK1907854T3 (da) Monoklonale antistoffer, hybridomcellelinjer, fremgangsmåder og kits til detektion af phytase
BRPI0509495A2 (pt) anticorpo humanizado
WO2006001965A3 (en) Reducing the risk of human anti-human antibodies through v gene manipulation
PL1718678T3 (pl) Przeciwciało monoklonalne przeciw ludzkiej tenascynie