ZA200801103B - Tricyclic compounds, a process for their preparation and pharmaceutical compositions containing them - Google Patents

Tricyclic compounds, a process for their preparation and pharmaceutical compositions containing them

Info

Publication number: ZA200801103B
Authority: ZA; South Africa
Prior art keywords: preparation; pharmaceutical compositions; compositions containing; tricyclic compounds; tricyclic
Prior art date: 2007-02-02

Application number

ZA200801103A

Other languages

English (en)

Inventor

Casara Patrick

Le Diguarher Thierry

Geneste Olivier

Hickman John

Original Assignee

Servier Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-02-02

Filing date

2008-02-01

Publication date

2008-12-31

2008-02-01 Application filed by Servier Lab filed Critical Servier Lab

2008-12-31 Publication of ZA200801103B publication Critical patent/ZA200801103B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Engineering & Computer Science (AREA)
Hematology (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Indole Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)

ZA200801103A 2007-02-02 2008-02-01 Tricyclic compounds, a process for their preparation and pharmaceutical compositions containing them ZA200801103B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR0700741A FR2912145B1 (fr)	2007-02-02	2007-02-02	Nouveaux derives tricycliques,leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number	Publication Date
ZA200801103B true ZA200801103B (en)	2008-12-31

Family

ID=38219469

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA200801103A ZA200801103B (en)	2007-02-02	2008-02-01	Tricyclic compounds, a process for their preparation and pharmaceutical compositions containing them

Country Status (45)

Country	Link
US (1)	US20080188460A1 (zh)
EP (1)	EP1953161B1 (zh)
JP (1)	JP2008266296A (zh)
KR (1)	KR100997027B1 (zh)
CN (1)	CN101270120A (zh)
AP (1)	AP2009004945A0 (zh)
AR (1)	AR065131A1 (zh)
AT (1)	ATE440842T1 (zh)
AU (1)	AU2008200499A1 (zh)
BR (1)	BRPI0800988A2 (zh)
CA (1)	CA2619897C (zh)
CL (1)	CL2008000318A1 (zh)
CO (1)	CO6230990A2 (zh)
CR (1)	CR10953A (zh)
CY (1)	CY1109637T1 (zh)
DE (1)	DE602008000104D1 (zh)
DK (1)	DK1953161T3 (zh)
EA (1)	EA014672B1 (zh)
EC (1)	ECSP099546A (zh)
ES (1)	ES2332337T3 (zh)
FR (1)	FR2912145B1 (zh)
GE (1)	GEP20115186B (zh)
GT (1)	GT200900217A (zh)
HR (1)	HRP20090565T1 (zh)
IL (1)	IL200128A0 (zh)
JO (1)	JO2616B1 (zh)
MA (1)	MA29725B1 (zh)
MX (1)	MX2008001504A (zh)
MY (1)	MY144633A (zh)
NI (1)	NI200900147A (zh)
NZ (1)	NZ565643A (zh)
PA (1)	PA8768301A1 (zh)
PE (1)	PE20081703A1 (zh)
PL (1)	PL1953161T3 (zh)
PT (1)	PT1953161E (zh)
RS (1)	RS51133B (zh)
SA (1)	SA08290043B1 (zh)
SG (1)	SG144892A1 (zh)
SI (1)	SI1953161T1 (zh)
SV (1)	SV2009003348A (zh)
TN (1)	TN2009000307A1 (zh)
TW (1)	TW200838532A (zh)
UA (1)	UA90726C2 (zh)
WO (1)	WO2008110691A1 (zh)
ZA (1)	ZA200801103B (zh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BRPI0716539A2 (pt)	2006-09-07	2016-11-01	Emisphere Tech Inc	métodos para sintetização de ácido n-(8-[2-hidroxibenzoil]amino) caprílico e de sal de sódio deste
FR2933983B1 (fr) *	2008-07-15	2010-08-27	Servier Lab	Nouveaux derives tricycliques,leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
CN106986875A (zh) *	2009-04-23	2017-07-28	Abbvie 公司	5‑ht受体的调节剂和其使用方法
US8546377B2 (en) *	2009-04-23	2013-10-01	Abbvie Inc.	Modulators of 5-HT receptors and methods of use thereof
US8518933B2 (en) *	2009-04-23	2013-08-27	Abbvie Inc.	Modulators of 5-HT receptors and methods of use thereof
EA020586B1 (ru) *	2009-09-10	2014-12-30	Новартис Аг	СУЛЬФОНАМИДЫ В КАЧЕСТВЕ ИНГИБИТОРОВ БЕЛКОВ СЕМЕЙСТВА Bcl-2, ПРЕДНАЗНАЧЕННЫЕ ДЛЯ ЛЕЧЕНИЯ РАКА
CN102584744B (zh) *	2011-01-06	2015-07-01	上海药明康德新药开发有限公司	4-(4-((2-(4-氯苯基)-5,5-二甲基环己基-1-烯)甲基)哌嗪-1-基)苯甲酸的合成方法
WO2013053045A1 (en)	2011-10-12	2013-04-18	Beta Pharma Canada Inc.	Heterocyclic molecules as apoptosis inducers
TWI620733B (zh) *	2013-05-21	2018-04-11	拜耳作物科學股份有限公司	製備特定肟類及肟醚類之改良方法
JOP20190239A1 (ar)	2017-04-19	2019-10-09	Neurocrine Biosciences Inc	مركبات مثبطة لـ vmat2 وتركيبات منها

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3899490A (en) *	1968-01-12	1975-08-12	Pfizer	Hexahydro pyrazinoquinolines
DE2362539C2 (de) *	1973-12-17	1986-05-07	Merck Patent Gmbh, 6100 Darmstadt	2-Acyl-4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isochinoline, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US5688950A (en) *	1996-04-23	1997-11-18	Neurogen Corporation	Tricyclic aminoalkylcarboxamides; novel dopamine D3 receptor subtype specific ligands
JP2000169475A (ja) *	1998-07-24	2000-06-20	Dai Ichi Seiyaku Co Ltd	ピラゾ―ル誘導体およびその塩
US6180629B1 (en) *	1998-08-14	2001-01-30	Cell Pathways, Inc.	[4,5]-Fused-1,3-disubstituted-1,2-diazine-6-one derivatives with nitrogen containing substitutents in position one for the treatment of neoplasia
US6190629B1 (en)	1999-04-16	2001-02-20	Cbl Technologies, Inc.	Organic acid scrubber and methods
US7919493B2 (en) *	2000-04-12	2011-04-05	Pharma Mar, S.A.	Anititumoral ecteinascidin derivatives
EP1325008B1 (en) *	2000-07-31	2005-10-05	F. Hoffmann-La Roche Ag	Piperazine derivatives
ATE423104T1 (de) *	2001-11-03	2009-03-15	Astrazeneca Ab	Quinazolin derivate als antitumor-mittel
JP2005517684A (ja) *	2001-12-21	2005-06-16	キングファーマシューティカルズリサーチアンドディベロップメントインコーポレイテッド	チロシル誘導体及びｐ２ｘ７受容体モジュレーターとしてのそれらの使用
FR2841243B1 (fr) *	2002-06-19	2004-08-20	Servier Lab	Nouveaux derives de 3-(4-oxo-4h-chromen-2yl)-(1h)-quinolein- 4-ones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
EP1578424A4 (en) *	2002-12-12	2007-08-08	Cytovia Inc	SUBSTITUTED 1-BENZOYL-3-CYANOPYRROLO1,2-A \| CHINOLINES AND THEIR ANALOGUES AS ACTIVATORS OF CASPASES AND INDUCTORS OF APOPTOSIS
WO2005049593A2 (en) *	2003-11-13	2005-06-02	Abbott Laboratories	N-acylsulfonamide apoptosis promoters
JP4734119B2 (ja) *	2004-02-12	2011-07-27	田辺三菱製薬株式会社	インダゾール化合物及びその医薬用途
US7790712B2 (en) *	2005-03-17	2010-09-07	Boehringer Ingelheim Pharmaceutical, Inc.	Substituted [1,4]diazepino[1,2-A]indoles and azepino[1,2-A]indoles as anti-cytokine inhibitors
WO2009102864A1 (en) *	2008-02-12	2009-08-20	Stanford University	Hedgehog pathway antagonists and methods of use

2007
- 2007-02-02 FR FR0700741A patent/FR2912145B1/fr not_active Expired - Fee Related
2008
- 2008-01-23 PE PE2008000167A patent/PE20081703A1/es not_active Application Discontinuation
- 2008-01-24 US US12/011,225 patent/US20080188460A1/en not_active Abandoned
- 2008-01-28 MY MYPI20080152A patent/MY144633A/en unknown
- 2008-01-28 GE GEAP200810489A patent/GEP20115186B/en unknown
- 2008-01-28 MA MA30601A patent/MA29725B1/fr unknown
- 2008-01-29 UA UAA200801063A patent/UA90726C2/ru unknown
- 2008-01-30 SA SA08290043A patent/SA08290043B1/ar unknown
- 2008-01-31 BR BRPI0800988-0A patent/BRPI0800988A2/pt not_active IP Right Cessation
- 2008-01-31 SG SG200800896-3A patent/SG144892A1/en unknown
- 2008-01-31 MX MX2008001504A patent/MX2008001504A/es active IP Right Grant
- 2008-02-01 AR ARP080100421A patent/AR065131A1/es unknown
- 2008-02-01 EP EP08290088A patent/EP1953161B1/fr active Active
- 2008-02-01 SI SI200830004T patent/SI1953161T1/sl unknown
- 2008-02-01 KR KR1020080010639A patent/KR100997027B1/ko not_active Expired - Fee Related
- 2008-02-01 RS RSP-2009/0449A patent/RS51133B/sr unknown
- 2008-02-01 AT AT08290088T patent/ATE440842T1/de active
- 2008-02-01 PL PL08290088T patent/PL1953161T3/pl unknown
- 2008-02-01 DE DE602008000104T patent/DE602008000104D1/de active Active
- 2008-02-01 NZ NZ565643A patent/NZ565643A/en unknown
- 2008-02-01 JP JP2008022515A patent/JP2008266296A/ja active Pending
- 2008-02-01 ES ES08290088T patent/ES2332337T3/es active Active
- 2008-02-01 AP AP2009004945A patent/AP2009004945A0/xx unknown
- 2008-02-01 TW TW097104070A patent/TW200838532A/zh unknown
- 2008-02-01 WO PCT/FR2008/000121 patent/WO2008110691A1/fr not_active Ceased
- 2008-02-01 AU AU2008200499A patent/AU2008200499A1/en not_active Abandoned
- 2008-02-01 EA EA200800235A patent/EA014672B1/ru not_active IP Right Cessation
- 2008-02-01 PT PT08290088T patent/PT1953161E/pt unknown
- 2008-02-01 PA PA20088768301A patent/PA8768301A1/es unknown
- 2008-02-01 CA CA2619897A patent/CA2619897C/fr not_active Expired - Fee Related
- 2008-02-01 CL CL200800318A patent/CL2008000318A1/es unknown
- 2008-02-01 ZA ZA200801103A patent/ZA200801103B/xx unknown
- 2008-02-01 DK DK08290088T patent/DK1953161T3/da active
- 2008-02-02 JO JOP/2008/0039A patent/JO2616B1/ar active
- 2008-02-02 CN CNA2008100963808A patent/CN101270120A/zh active Pending
2009
- 2009-07-23 TN TNP2009000307A patent/TN2009000307A1/fr unknown
- 2009-07-24 CR CR10953A patent/CR10953A/es unknown
- 2009-07-28 EC EC2009009546A patent/ECSP099546A/es unknown
- 2009-07-28 IL IL200128A patent/IL200128A0/en unknown
- 2009-07-29 NI NI200900147A patent/NI200900147A/es unknown
- 2009-07-31 GT GT200900217A patent/GT200900217A/es unknown
- 2009-07-31 SV SV2009003348A patent/SV2009003348A/es unknown
- 2009-07-31 CO CO09080210A patent/CO6230990A2/es not_active Application Discontinuation
- 2009-10-22 HR HR20090565T patent/HRP20090565T1/hr unknown
- 2009-11-24 CY CY20091101213T patent/CY1109637T1/el unknown

Also Published As

Publication number	Publication date
MA29725B1 (fr)	2008-09-01
RS51133B (sr)	2010-10-31
AU2008200499A1 (en)	2008-08-21
KR100997027B1 (ko)	2010-11-25
CL2008000318A1 (es)	2008-08-08
CA2619897A1 (fr)	2008-08-02
DK1953161T3 (da)	2009-11-30
CR10953A (es)	2009-09-09
HRP20090565T1 (hr)	2009-12-31
PT1953161E (pt)	2009-10-26
JO2616B1 (ar)	2011-11-01
SA08290043B1 (ar)	2011-06-22
DE602008000104D1 (de)	2009-10-08
CO6230990A2 (es)	2010-12-20
NZ565643A (en)	2009-05-31
EP1953161A1 (fr)	2008-08-06
WO2008110691A1 (fr)	2008-09-18
IL200128A0 (en)	2010-04-15
AR065131A1 (es)	2009-05-20
BRPI0800988A2 (pt)	2008-11-25
US20080188460A1 (en)	2008-08-07
ATE440842T1 (de)	2009-09-15
FR2912145B1 (fr)	2009-03-06
PL1953161T3 (pl)	2010-01-29
SG144892A1 (en)	2008-08-28
ES2332337T3 (es)	2010-02-02
MX2008001504A (es)	2009-02-24
PA8768301A1 (es)	2008-11-19
FR2912145A1 (fr)	2008-08-08
TN2009000307A1 (fr)	2010-12-31
NI200900147A (es)	2010-02-15
GT200900217A (es)	2011-09-14
KR20080072574A (ko)	2008-08-06
PE20081703A1 (es)	2009-01-14
CN101270120A (zh)	2008-09-24
MY144633A (en)	2011-10-14
SV2009003348A (es)	2010-02-01
UA90726C2 (ru)	2010-05-25
CY1109637T1 (el)	2014-08-13
SI1953161T1 (sl)	2009-12-31
TW200838532A (en)	2008-10-01
CA2619897C (fr)	2011-06-14
ECSP099546A (es)	2009-08-28
EA200800235A1 (ru)	2008-08-29
EA014672B1 (ru)	2010-12-30
JP2008266296A (ja)	2008-11-06
EP1953161B1 (fr)	2009-08-26
GEP20115186B (en)	2011-03-25
AP2009004945A0 (en)	2009-08-31

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