ZA200603475B - Disulfide, sulfide, sulfoxide, and sulfone derivatives of cyclic sugars and uses thereof - Google Patents

Disulfide, sulfide, sulfoxide, and sulfone derivatives of cyclic sugars and uses thereof

Info

Publication number: ZA200603475B
Authority: ZA; South Africa
Prior art keywords: disulfide; sulfoxide; sulfide; sulfone derivatives; cyclic sugars
Prior art date: 2003-10-03

Application number

ZA200603475A

Other languages

English (en)

Inventor

Repolles Moliner Jose

Pubill Coy Francisco

Salas Perez-Rasilla Eduardo

Original Assignee

Lscer S A

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-10-03

Filing date

2006-05-02

Publication date

2007-09-26

2006-05-02 Application filed by Lscer S A filed Critical Lscer S A

2007-09-26 Publication of ZA200603475B publication Critical patent/ZA200603475B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Cardiology (AREA)
Diabetes (AREA)
Heart & Thoracic Surgery (AREA)
Hematology (AREA)
Epidemiology (AREA)
Pulmonology (AREA)
Obesity (AREA)
Endocrinology (AREA)
Hospice & Palliative Care (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Biochemistry (AREA)
Immunology (AREA)
Toxicology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Dermatology (AREA)
Gynecology & Obstetrics (AREA)
Reproductive Health (AREA)
Emergency Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

ZA200603475A 2003-10-03 2006-05-02 Disulfide, sulfide, sulfoxide, and sulfone derivatives of cyclic sugars and uses thereof ZA200603475B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
ES200302368A ES2258365B1 (es)	2003-10-03	2003-10-03	Derivados de disulfuro, sulfuro, sulfoxido y sulfona de azucares ciclicos y sus usos.

Publications (1)

Publication Number	Publication Date
ZA200603475B true ZA200603475B (en)	2007-09-26

Family

ID=34451643

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA200603475A ZA200603475B (en)	2003-10-03	2006-05-02	Disulfide, sulfide, sulfoxide, and sulfone derivatives of cyclic sugars and uses thereof

Country Status (34)

Country	Link
US (3)	US7521571B2 (fr)
EP (1)	EP1668017B1 (fr)
JP (2)	JP4809769B2 (fr)
KR (1)	KR101141683B1 (fr)
CN (1)	CN1863805B (fr)
AP (1)	AP1976A (fr)
AR (1)	AR045962A1 (fr)
AT (1)	ATE423781T1 (fr)
AU (1)	AU2004281916B2 (fr)
BR (1)	BRPI0415020A (fr)
CA (1)	CA2540500C (fr)
DE (2)	DE112004001860T5 (fr)
DK (1)	DK1668017T3 (fr)
EA (1)	EA008942B1 (fr)
EC (1)	ECSP066542A (fr)
ES (2)	ES2258365B1 (fr)
GB (1)	GB2421241B (fr)
GE (1)	GEP20084490B (fr)
GT (1)	GT200400200A (fr)
HR (1)	HRP20090152T3 (fr)
IL (1)	IL174371A0 (fr)
IS (1)	IS8436A (fr)
MX (1)	MXPA06003610A (fr)
NO (1)	NO20061872L (fr)
NZ (1)	NZ546043A (fr)
PA (1)	PA8614201A1 (fr)
PE (1)	PE20050436A1 (fr)
PL (1)	PL1668017T3 (fr)
PT (1)	PT1668017E (fr)
RS (1)	RS20060241A (fr)
SI (1)	SI1668017T1 (fr)
UY (1)	UY28547A1 (fr)
WO (1)	WO2005037842A1 (fr)
ZA (1)	ZA200603475B (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2258365B1 (es)	2003-10-03	2007-12-01	Lacer, S.A.	Derivados de disulfuro, sulfuro, sulfoxido y sulfona de azucares ciclicos y sus usos.
EP1941876A1 (fr) *	2006-12-28	2008-07-09	Lacer, S.A.	Derivés du mononitrite de l'isosorbide destinées au traitement de l'inflammation et l'hypertension oculaire
ES2332565B1 (es) *	2007-01-23	2010-10-21	Lacer, S.A.	Uso de derivados de mononitrato de dianhidrohexita como agentes antiinflamatorios.
JP2010518169A (ja) *	2007-02-13	2010-05-27	ギリアード・パロ・アルト・インコーポレイテッド	心血管疾患の処置のためのラノラジンの使用
JP2010518170A (ja) *	2007-02-13	2010-05-27	ギリアード・パロ・アルト・インコーポレイテッド	冠微小血管疾患の処置のためのラノラジンの使用
US20080193530A1 (en) *	2007-02-13	2008-08-14	Brent Blackburn	Use of ranolazine for the treatment of non-coronary microvascular diseases
US20090111826A1 (en) *	2007-02-13	2009-04-30	Louis Lange	Use of ranolazine for the treatment of cardiovascular diseases
WO2008116083A1 (fr) *	2007-03-22	2008-09-25	Cv Therapeutics, Inc.	Utilisation de ranolazine contre un taux élevé de peptide natriurétique de type b
KR20100033490A (ko) *	2007-05-31	2010-03-30	질레드 팔로 알토 인코포레이티드	상승된 뇌-형 나트륨이뇨 펩티드에 대한 라놀라진
IE20070934A1 (en)	2007-12-21	2009-06-24	Trinity College Dublin	Efficient aspirin prodrugs
WO2009098113A1 (fr) *	2008-02-07	2009-08-13	Nicox S.A.	Composés donneurs d'oxyde nitrique
EP2149577B1 (fr) *	2008-07-22	2011-04-27	Lacer, S.A.	Nouveau procédé stéréospécifique pour la préparation de composés de dioxa-bicyclooctane
EP2149576A1 (fr) *	2008-07-22	2010-02-03	Lacer, S.A.	Nitrates d'isosorbide ayant une activité vasodilatatrice
EP2177216A1 (fr) *	2008-10-13	2010-04-21	Lacer, S.A.	Utilisation de dérivés de mononitrate de dianhydrohexite comme agents de cicatrisation
WO2010055138A1 (fr) *	2008-11-14	2010-05-20	Lacer, S.A.	Nouveau procédé stéréospécifique pour la préparation de composés de dioxabicyclooctane
EP2199294A1 (fr) *	2008-12-19	2010-06-23	Lacer, S.A.	Nouveau procédé stéréospécifique pour la préparation de composé de nitrate de dioxa bicyclooctane
CA2822747A1 (fr) *	2009-12-23	2011-06-30	Arca Biopharma, Inc.	Utilisation de s-(6-nitro-oxi-hexahydro-furo[3,2-b]thioacetate dans le traitement de troubles cardiovasculaires associes a un dysfonctionnement de la synthase d'oxyde
FR2977252B1 (fr) *	2011-06-30	2013-08-02	Seppic Sa	Nouveaux esters de derives n-acyles d'acides amines et d'isosorbide, procede pour leur preparation, et utilisation en cosmetique et comme medicament.
US9388274B2 (en)	2011-12-16	2016-07-12	3M Innovative Properties Company	Mercapto-containing bisanhydrohexitol derivatives and uses thereof
RU2015139514A (ru) *	2013-03-05	2017-04-07	Арчер Дэниелс Мидлэнд Компани	Монотрифлаты изогексида и способ их синтеза
CN116173012A (zh) *	2022-12-05	2023-05-30	温州医科大学	白当归脑在制备缺血性脑卒中神经保护用药物中的应用

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AU465217B2 (en) *	1971-04-29	1975-09-18	American Home Products Corporation	Mononitrte esters of 1,4:3, 6-dianhydro-d-glucitol
US3886186A (en)	1971-04-29	1975-05-27	American Home Prod	Mononitrate esters of 1,4:3,6-dianhydro-d-glucitol
DE3102947A1 (de)	1981-01-29	1982-09-02	Heinrich Mack Nachf., 7918 Illertissen	Verfahren zur herstellung von isosorbid-5-nitrat
IT1204571B (it) *	1987-05-08	1989-03-10	Chiesi Farma Spa	Esteri di 1,4:3,6-dianidrosorbitolo-2-mononitrato e 5-mononitrato,loro procedimento di preparazione e loro composizioni farmaceutiche
US4891373A (en) *	1988-11-23	1990-01-02	Pfizer Inc.	Aminopropanol derivatives of 1,4:3,6-dianhydrohexitol nitrates, processes for their preparation and their use as medicaments
FR2680173A1 (fr) *	1991-08-07	1993-02-12	Hoechst Lab	Nitrates organiques, leurs procedes de preparation et leur utilisation dans le traitement de maladies cardiovasculaires .
CA2141435A1 (fr) *	1992-07-30	1994-02-17	William Byrne	Ester d'un nitrate organique et d'un salicylate
DE4410997A1 (de) *	1994-03-30	1995-10-26	Isis Pharma Gmbh	Pharmazeutische Zubereitungen und Arzneistoffe zur Prävention und Behandlung endothelialer Dysfunktionen
IL120531A (en) *	1997-03-26	2006-12-31	Yissum Res Dev Co	Nitric oxide donors and pharmaceutical compositions containing them
ES2142773B1 (es) *	1998-10-07	2001-01-01	Lacer Sa	Derivados de mononitrato de isosorbida y su empleo como agentes vasodilatadores con tolerancia desminuida.
US20020013483A1 (en)	2000-07-13	2002-01-31	Consortium Fur Elektrochemische Industrie Gmbh	Process for the preparation of dianhydrohexitol bisacylates
EP1337283A4 (fr) *	2000-10-27	2005-05-18	Nitromed Inc	Methodes de traitement de maladies vasculaires caracterisees par une insuffisance en monoxyde d'azote
UA63467A (en)	2003-04-22	2004-01-15		Pharmaceutical composition of organic nitrates, dosage form based on pharmaceutical composition of organic nitrates and method of manufacture
ES2258365B1 (es) *	2003-10-03	2007-12-01	Lacer, S.A.	Derivados de disulfuro, sulfuro, sulfoxido y sulfona de azucares ciclicos y sus usos.

2003
- 2003-10-03 ES ES200302368A patent/ES2258365B1/es not_active Expired - Fee Related
2004
- 2004-09-29 CN CN2004800289355A patent/CN1863805B/zh not_active Expired - Fee Related
- 2004-09-29 DE DE112004001860T patent/DE112004001860T5/de not_active Withdrawn
- 2004-09-29 AU AU2004281916A patent/AU2004281916B2/en not_active Ceased
- 2004-09-29 AP AP2006003605A patent/AP1976A/xx active
- 2004-09-29 GB GB0605574A patent/GB2421241B/en not_active Expired - Fee Related
- 2004-09-29 SI SI200431109T patent/SI1668017T1/sl unknown
- 2004-09-29 WO PCT/EP2004/010882 patent/WO2005037842A1/fr not_active Ceased
- 2004-09-29 KR KR1020067006283A patent/KR101141683B1/ko not_active Expired - Fee Related
- 2004-09-29 US US10/544,237 patent/US7521571B2/en not_active Expired - Fee Related
- 2004-09-29 HR HR20090152T patent/HRP20090152T3/xx unknown
- 2004-09-29 AT AT04765682T patent/ATE423781T1/de not_active IP Right Cessation
- 2004-09-29 CA CA2540500A patent/CA2540500C/fr not_active Expired - Fee Related
- 2004-09-29 BR BRPI0415020-1A patent/BRPI0415020A/pt not_active IP Right Cessation
- 2004-09-29 ES ES04765682T patent/ES2322468T3/es not_active Expired - Lifetime
- 2004-09-29 RS YUP-2006/0241A patent/RS20060241A/sr unknown
- 2004-09-29 PT PT04765682T patent/PT1668017E/pt unknown
- 2004-09-29 PL PL04765682T patent/PL1668017T3/pl unknown
- 2004-09-29 MX MXPA06003610A patent/MXPA06003610A/es active IP Right Grant
- 2004-09-29 EA EA200600694A patent/EA008942B1/ru not_active IP Right Cessation
- 2004-09-29 NZ NZ546043A patent/NZ546043A/en unknown
- 2004-09-29 JP JP2006530042A patent/JP4809769B2/ja not_active Expired - Fee Related
- 2004-09-29 GE GEAP20049372A patent/GEP20084490B/en unknown
- 2004-09-29 DE DE602004019666T patent/DE602004019666D1/de not_active Expired - Lifetime
- 2004-09-29 DK DK04765682T patent/DK1668017T3/da active
- 2004-09-29 EP EP04765682A patent/EP1668017B1/fr not_active Expired - Lifetime
- 2004-09-30 PE PE2004000957A patent/PE20050436A1/es not_active Application Discontinuation
- 2004-10-01 AR ARP040103576A patent/AR045962A1/es unknown
- 2004-10-01 GT GT200400200A patent/GT200400200A/es unknown
- 2004-10-01 UY UY28547A patent/UY28547A1/es not_active Application Discontinuation
- 2004-10-01 PA PA20048614201A patent/PA8614201A1/es unknown
2006
- 2006-03-16 IL IL174371A patent/IL174371A0/en unknown
- 2006-04-27 NO NO20061872A patent/NO20061872L/no not_active Application Discontinuation
- 2006-05-02 ZA ZA200603475A patent/ZA200603475B/xx unknown
- 2006-05-03 EC EC2006006542A patent/ECSP066542A/es unknown
- 2006-05-03 IS IS8436A patent/IS8436A/is unknown
2009
- 2009-03-09 US US12/400,394 patent/US7777058B2/en not_active Expired - Fee Related
2010
- 2010-04-06 US US12/755,103 patent/US8541607B2/en not_active Expired - Fee Related
- 2010-10-08 JP JP2010228789A patent/JP2011012081A/ja active Pending

Also Published As

Publication number	Publication date
JP4809769B2 (ja)	2011-11-09
NO20061872L (no)	2006-06-30
ES2258365B1 (es)	2007-12-01
ES2322468T3 (es)	2009-06-22
US7777058B2 (en)	2010-08-17
DE602004019666D1 (de)	2009-04-09
AP2006003605A0 (en)	2006-04-30
ES2258365A1 (es)	2006-08-16
AU2004281916B2 (en)	2010-10-21
ECSP066542A (es)	2006-10-17
MXPA06003610A (es)	2006-06-05
HK1092807A1 (en)	2007-02-16
HRP20090152T3 (en)	2009-05-31
NZ546043A (en)	2009-02-28
ATE423781T1 (de)	2009-03-15
WO2005037842A1 (fr)	2005-04-28
KR20060066743A (ko)	2006-06-16
GB0605574D0 (en)	2006-04-26
GB2421241A (en)	2006-06-21
CN1863805B (zh)	2010-06-16
SI1668017T1 (sl)	2009-08-31
RS20060241A (sr)	2008-06-05
GEP20084490B (en)	2008-09-25
GT200400200A (es)	2005-05-23
PL1668017T3 (pl)	2009-07-31
US20060235052A1 (en)	2006-10-19
JP2011012081A (ja)	2011-01-20
PT1668017E (pt)	2009-03-09
AP1976A (en)	2009-03-16
CA2540500C (fr)	2012-08-28
EA200600694A1 (ru)	2006-10-27
DK1668017T3 (da)	2009-05-11
US8541607B2 (en)	2013-09-24
BRPI0415020A (pt)	2006-11-07
EP1668017B1 (fr)	2009-02-25
DE112004001860T5 (de)	2006-07-27
AR045962A1 (es)	2005-11-16
CN1863805A (zh)	2006-11-15
US20100196387A1 (en)	2010-08-05
US7521571B2 (en)	2009-04-21
PA8614201A1 (es)	2005-05-24
GB2421241B (en)	2008-04-16
EP1668017A1 (fr)	2006-06-14
US20090169560A1 (en)	2009-07-02
JP2007507451A (ja)	2007-03-29
IL174371A0 (en)	2006-08-01
AU2004281916A1 (en)	2005-04-28
CA2540500A1 (fr)	2005-04-28
UY28547A1 (es)	2005-04-29
PE20050436A1 (es)	2005-06-23
IS8436A (is)	2006-05-03
EA008942B1 (ru)	2007-10-26
KR101141683B1 (ko)	2012-05-07

Publication	Publication Date	Title
AP1976A (en)	2009-03-16	Disulfide, sulfide, sulfoxide and sulfone derivatives of cyclic sugars and uses thereof
DK1919458T3 (da)	2012-08-20	Syreresistent cysteamin, cystamin og derivater deraf
DK1574452T3 (da)	2007-02-05	Lukket kapsel med åbnemiddel
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