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YU2692A - Novi derivati tetrazola i postupak za njihovo pripremanje - Google Patents

Novi derivati tetrazola i postupak za njihovo pripremanje

Info

Publication number
YU2692A
YU2692A YU2692A YU2692A YU2692A YU 2692 A YU2692 A YU 2692A YU 2692 A YU2692 A YU 2692A YU 2692 A YU2692 A YU 2692A YU 2692 A YU2692 A YU 2692A
Authority
YU
Yugoslavia
Prior art keywords
tetrazole derivatives
procedure
preparation
new
methyl
Prior art date
Application number
YU2692A
Other languages
English (en)
Other versions
YU48089B (sh
Inventor
D. Binder
J. Weinberger
A. Koch
Original Assignee
Chemisch Pharmazeutische Forschungs G.M.B.H.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemisch Pharmazeutische Forschungs G.M.B.H. filed Critical Chemisch Pharmazeutische Forschungs G.M.B.H.
Priority to SI9210026A priority Critical patent/SI9210026A/sl
Publication of YU2692A publication Critical patent/YU2692A/sh
Publication of YU48089B publication Critical patent/YU48089B/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Reinforced Plastic Materials (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Steroid Compounds (AREA)

Abstract

NOVI DERIVATI TETRAZOLA I POSTUPAK ZA NJIHOVO DOBIJANJE, opisani su novi derivati tetrazola sa formulom u kojoj predstavljaju R1 zasićen ili nezasićen, ravan ili razvejan (C1-C6)-alkilni ostatak i R2 metil ili etil, kao i njihove farmaceutski upotrebljive soli. Dobijamo ih reakcijom metilestra ili etilestra 1-((2'-(tetrazol-5-il)bifenil-4-il)metil-2-alkil-4-hlor-1H-imidazol-5-karbo ksilne kiseline, koji je zaštićen u položaju 1 tetrazolovog prstena, sa kalijumovim ili natrijumovim N-hidroksi-metan- ili etan-im-idamidom i predstojeće odcepljivanje zaštitne grupe.
YU2692A 1991-01-31 1992-01-13 Novi derivati tetrazola i postupak za njihovo pripremanje YU48089B (sh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SI9210026A SI9210026A (en) 1991-01-31 1992-01-13 Novel tetrazole derivatives, process for their preparation and their use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0020991A AT395853B (de) 1991-01-31 1991-01-31 Neue imidazolderivate, verfahren zu ihrer herstellung und ihre verwendung

Publications (2)

Publication Number Publication Date
YU2692A true YU2692A (sh) 1994-11-15
YU48089B YU48089B (sh) 1997-01-08

Family

ID=3484393

Family Applications (1)

Application Number Title Priority Date Filing Date
YU2692A YU48089B (sh) 1991-01-31 1992-01-13 Novi derivati tetrazola i postupak za njihovo pripremanje

Country Status (27)

Country Link
US (1) US5254574A (sh)
EP (1) EP0497121B1 (sh)
JP (1) JPH0641099A (sh)
KR (1) KR920014802A (sh)
CN (1) CN1034662C (sh)
AT (2) AT395853B (sh)
AU (1) AU642575B2 (sh)
CA (1) CA2060387A1 (sh)
CZ (1) CZ27592A3 (sh)
DE (1) DE59208058D1 (sh)
DK (1) DK0497121T3 (sh)
EG (1) EG19886A (sh)
ES (1) ES2100242T3 (sh)
FI (1) FI920349L (sh)
GR (1) GR3022686T3 (sh)
HU (1) HUT62583A (sh)
IE (1) IE914501A1 (sh)
IL (1) IL100621A (sh)
LT (1) LTIP1518A (sh)
LV (1) LV10446B (sh)
MY (1) MY106314A (sh)
NO (1) NO179837C (sh)
NZ (1) NZ241293A (sh)
RU (1) RU2078764C1 (sh)
SI (1) SI9210026A (sh)
YU (1) YU48089B (sh)
ZA (1) ZA92155B (sh)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1255802B (it) * 1992-08-07 1995-11-16 Luso Farmaco Inst Derivati imidazolici ad attivita' a ii antagonista
GB9507203D0 (en) * 1995-04-07 1995-05-31 Smithkline Beecham Plc Novel compounds
HU226617B1 (en) * 1998-12-14 2009-04-28 Cytrx Corp Optically active pyridyl-4h-1,2,4-oxadiazine derivatives, and pharmaceutical composition containing the compound as active ingredient
SE9903028D0 (sv) 1999-08-27 1999-08-27 Astra Ab New use
PL1658281T3 (pl) * 2003-08-27 2010-12-31 Zentiva Ks Sposób usuwania trifenylometanowej grupy zabezpieczającej
US7803940B2 (en) * 2006-11-24 2010-09-28 Takeda Pharmaceutical Company Limited Heteromonocyclic compound or a salt thereof having strong antihypertensive action, insulin sensitizing activity and the like production thereof and use thereof for prophylaxis or treatment of cardiovascular diseases, metabolic diseases and/or central nervous system diseases
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
WO2008151257A2 (en) 2007-06-04 2008-12-11 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
WO2009149279A2 (en) 2008-06-04 2009-12-10 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
CA2730603C (en) 2008-07-16 2019-09-24 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
DE102013202306B4 (de) 2013-02-13 2014-12-18 Adidas Ag Sohle für einen Schuh
EP2970384A1 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
WO2014151200A2 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
USD776410S1 (en) 2013-04-12 2017-01-17 Adidas Ag Shoe
AU2014274812B2 (en) 2013-06-05 2018-09-27 Bausch Health Ireland Limited Ultra-pure agonists of guanylate cyclase C, method of making and using same
USD783264S1 (en) 2015-09-15 2017-04-11 Adidas Ag Shoe

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0000452B1 (fr) * 1977-07-12 1981-05-06 Synthelabo Dérivés d'oxadiazole-1,2,4, leur préparation et leur application en thérapeutique.
US4771051A (en) * 1985-05-17 1988-09-13 A/S Ferrosan 3-substituted-4,5-dihydro-5-oxo imidazoquinazolines, their preparation, and their use in treating benzodiazepin receptor-related ailments
CA1334092C (en) * 1986-07-11 1995-01-24 David John Carini Angiotensin ii receptor blocking imidazoles
DE3627155A1 (de) * 1986-08-11 1988-02-18 Schering Ag Imidazol-derivate
US4820843A (en) * 1987-05-22 1989-04-11 E. I. Du Pont De Nemours And Company Tetrazole intermediates to antihypertensive compounds
US5015651A (en) * 1988-01-07 1991-05-14 E. I. Du Pont De Nemours And Company Treatment of hypertension with 1,2,4-angiotensin II antagonists
CA1338238C (en) * 1988-01-07 1996-04-09 David John Carini Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids
US5064825A (en) * 1989-06-01 1991-11-12 Merck & Co., Inc. Angiotensin ii antagonists
FI916129A7 (fi) * 1989-06-30 1991-12-27 Du Pont Substituoituja imidatsoleja

Also Published As

Publication number Publication date
ATE149164T1 (de) 1997-03-15
HU9200292D0 (en) 1992-04-28
CN1063689A (zh) 1992-08-19
FI920349A7 (fi) 1992-08-01
YU48089B (sh) 1997-01-08
NO179837B (no) 1996-09-16
LTIP1518A (en) 1995-06-26
FI920349A0 (fi) 1992-01-27
GR3022686T3 (en) 1997-05-31
AT395853B (de) 1993-03-25
RU2078764C1 (ru) 1997-05-10
DE59208058D1 (de) 1997-04-03
CZ27592A3 (en) 1993-03-17
ES2100242T3 (es) 1997-06-16
ZA92155B (en) 1992-10-28
SI9210026A (en) 1994-09-30
HUT62583A (en) 1993-05-28
ATA20991A (de) 1992-08-15
IE914501A1 (en) 1992-07-29
EG19886A (en) 1996-05-31
NO179837C (no) 1996-12-27
NO920122D0 (no) 1992-01-09
LV10446B (en) 1995-10-20
FI920349L (fi) 1992-08-01
CA2060387A1 (en) 1992-08-01
NO920122L (no) 1992-08-03
AU642575B2 (en) 1993-10-21
EP0497121A1 (de) 1992-08-05
LV10446A (lv) 1995-02-20
KR920014802A (ko) 1992-08-25
US5254574A (en) 1993-10-19
JPH0641099A (ja) 1994-02-15
AU1063492A (en) 1992-08-06
CN1034662C (zh) 1997-04-23
NZ241293A (en) 1993-04-28
DK0497121T3 (da) 1997-05-05
MY106314A (en) 1995-04-29
EP0497121B1 (de) 1997-02-26
IL100621A0 (en) 1992-09-06
IL100621A (en) 1996-08-04

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