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YU2200A - Termodinamički stabilna modifikacija 1-(4-karbazoliloksi)-3-/2-(2-metoksifenoksi)etilamino/-2-propanola, postupak za njeno dobijanje i farmaceutske smeše koje je sadrže - Google Patents

Termodinamički stabilna modifikacija 1-(4-karbazoliloksi)-3-/2-(2-metoksifenoksi)etilamino/-2-propanola, postupak za njeno dobijanje i farmaceutske smeše koje je sadrže

Info

Publication number
YU2200A
YU2200A YU2200A YU2200A YU2200A YU 2200 A YU2200 A YU 2200A YU 2200 A YU2200 A YU 2200A YU 2200 A YU2200 A YU 2200A YU 2200 A YU2200 A YU 2200A
Authority
YU
Yugoslavia
Prior art keywords
carbazolyloxy
propanole
methoxyphenoxy
ethylamino
preparation
Prior art date
Application number
YU2200A
Other languages
English (en)
Inventor
Erhard Reinholz
Peter Beyer
Original Assignee
Roche Diagnostics Gmbh.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics Gmbh. filed Critical Roche Diagnostics Gmbh.
Publication of YU2200A publication Critical patent/YU2200A/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Ovaj pronalazak se odnosi na novu termodinamički stabilnu modifikaciju 1-(4-karbozoliloksi)-3-[2-(2-metoksifenoksi)etilamino]-2-propanola (karvedilola), njene farmakološki prihvatljive soli ili optički aktivne oblike, postupke za njeno dobijanje i farmaceutske smeše koje je sadrže.[The present invention relates to a new thermodynamically stable modification of 1-(4-carbazolyloxy)-3-[2-(2-methoxyphenoxy) ethylamino]-2-propanole (Carvedilol), pharmacologically acceptable salts, or optically active forms thereof, processes for the preparation, and pharmaceutical compositions containing it.
YU2200A 1997-07-22 1998-07-18 Termodinamički stabilna modifikacija 1-(4-karbazoliloksi)-3-/2-(2-metoksifenoksi)etilamino/-2-propanola, postupak za njeno dobijanje i farmaceutske smeše koje je sadrže YU2200A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97112491A EP0893440A1 (en) 1997-07-22 1997-07-22 Thermodynamically stable modification of 1-(4-carbazolyloxy)-3-[2-(2-methoxyphenoxy)ethylamino]-2-propanole, process for its preparation and pharmaceutical compositions containing it

Publications (1)

Publication Number Publication Date
YU2200A true YU2200A (sh) 2002-03-18

Family

ID=8227094

Family Applications (1)

Application Number Title Priority Date Filing Date
YU2200A YU2200A (sh) 1997-07-22 1998-07-18 Termodinamički stabilna modifikacija 1-(4-karbazoliloksi)-3-/2-(2-metoksifenoksi)etilamino/-2-propanola, postupak za njeno dobijanje i farmaceutske smeše koje je sadrže

Country Status (31)

Country Link
EP (2) EP0893440A1 (sh)
JP (1) JP2001510824A (sh)
KR (1) KR100336229B1 (sh)
CN (1) CN1125047C (sh)
AR (1) AR015133A1 (sh)
AT (1) ATE236123T1 (sh)
AU (1) AU740453B2 (sh)
BR (1) BR9810776A (sh)
CA (1) CA2296637C (sh)
CZ (1) CZ296947B6 (sh)
DE (1) DE69812964T2 (sh)
DK (1) DK1000027T3 (sh)
ES (1) ES2195366T3 (sh)
HR (1) HRP980406A2 (sh)
HU (1) HUP0003198A3 (sh)
IL (1) IL133677A (sh)
MA (1) MA26523A1 (sh)
MY (1) MY117734A (sh)
NO (1) NO313588B1 (sh)
NZ (1) NZ502136A (sh)
PE (1) PE96999A1 (sh)
PL (1) PL191602B1 (sh)
PT (1) PT1000027E (sh)
RU (1) RU2202542C2 (sh)
SI (1) SI1000027T1 (sh)
TR (1) TR200000148T2 (sh)
TW (1) TW505631B (sh)
UY (1) UY25108A1 (sh)
WO (1) WO1999005105A1 (sh)
YU (1) YU2200A (sh)
ZA (1) ZA986475B (sh)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003528914A (ja) * 2000-04-03 2003-09-30 エフ．ホフマン−ラ ロシュ アーゲー カルベジロールの濃縮溶液
EP1655285A1 (en) * 2000-06-28 2006-05-10 Teva Pharmaceutical Industries Ltd. Method for preparation of a crystalline form of carvedilol (form II)
KR20030017569A (ko) 2000-06-28 2003-03-03 테바 파마슈티컬 인더스트리즈 리미티드 카르베딜올
DE60212130D1 (en) * 2001-07-13 2006-07-20 Smithkline Beecham Corp Carvedilolpolymorph
US20050019399A1 (en) 2001-09-21 2005-01-27 Gina Fischer Controlled release solid dispersions
ES2291503T3 (es) * 2001-09-28 2008-03-01 F. Hoffmann-La Roche Ag Formas pseudopolimorficas de carvedilol.
HRP20040673A2 (en) 2002-01-15 2005-06-30 Teva Pharmaceutical Industries Ltd. Crystalline solids of carvedilol and processes for their preparation
WO2003092622A2 (en) * 2002-04-30 2003-11-13 Sb Pharmco Puerto Rico Inc. Carvedilol monocitrate monohydrate
JP2005533823A (ja) * 2002-06-27 2005-11-10 エスビー・ファルムコ・プエルト・リコ・インコーポレイテッド リン酸カルベジロール塩および／またはその溶媒和物、対応する組成物、および／または治療方法
CA2492084A1 (en) 2002-06-27 2004-01-08 Sb Pharmco Puerto Rico Inc. Carvedilol hydobromide
US20040151772A1 (en) * 2002-11-08 2004-08-05 Egalet A/S Controlled release carvedilol compositions
EP1610767B1 (en) 2003-03-26 2011-01-19 Egalet A/S Morphine controlled release system
EP1615888A1 (en) * 2003-04-21 2006-01-18 Matrix Laboratories Ltd Process for the preparation of carvedilol form-ii
SI21616A (sl) * 2003-09-02 2005-04-30 Krka, Tovarna Zdravil, D.D., Novo Mesto Nove kristalne oblike karvedilola
EP1686986A4 (en) * 2003-11-25 2009-05-27 Sb Pharmco Inc CARVEDILOL SALTS, CORRESPONDING COMPOSITIONS, METHODS OF ADMINISTRATION AND / OR TREATMENT
PT1838670E (pt) * 2004-12-09 2009-12-18 Zach System Spa Processo para a preparação de carvedilol e seus enantiómeros
KR20070088507A (ko) * 2005-06-09 2007-08-29 테바 파마슈티컬 인더스트리즈 리미티드 카베딜올의 결정질 형태 및 이것의 제조 방법
EP1991527A2 (en) 2006-06-28 2008-11-19 Teva Pharmaceutical Industries Ltd Polymorphous forms of carvedilol phosphate
RU2366653C2 (ru) * 2006-07-03 2009-09-10 Ооо "Нанокриохимия" Способ получения рентгеноаморфной модификации карведилола
US20080249317A1 (en) * 2007-04-04 2008-10-09 Apotex Inc. Novel amorphous form of carvedilol phosphate and processes for the preparation thereof
AU2008258596B2 (en) 2007-06-04 2013-02-14 Egalet Ltd Controlled release pharmaceutical compositions for prolonged effect
WO2010089132A1 (en) 2009-02-06 2010-08-12 Egalet A/S Immediate release composition resistant to abuse by intake of alcohol
EP2445487A2 (en) 2009-06-24 2012-05-02 Egalet Ltd. Controlled release formulations

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2815926A1 (de) * 1978-04-13 1979-10-18 Boehringer Mannheim Gmbh Neue carbazolyl-(4)-oxy-propanolamin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE2805404A1 (de) * 1978-02-09 1979-08-16 Merck Patent Gmbh 1-aryloxy-3-nitratoalkylamino-2-propanole und verfahren zu ihrer herstellung
DE3319027A1 (de) * 1983-05-26 1984-11-29 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur herstellung von optisch aktiven carbazol-derivaten, neue r- und s-carbazol-derivate, sowie arzneimittel, die diese verbindungen enthalten

Also Published As

Publication number Publication date
ES2195366T3 (es) 2003-12-01
PL338432A1 (en) 2000-11-06
MA26523A1 (fr) 2004-12-20
BR9810776A (pt) 2000-09-19
ATE236123T1 (de) 2003-04-15
TW505631B (en) 2002-10-11
JP2001510824A (ja) 2001-08-07
KR20010022097A (ko) 2001-03-15
DK1000027T3 (da) 2003-07-21
EP1000027B1 (en) 2003-04-02
DE69812964D1 (de) 2003-05-08
RU2202542C2 (ru) 2003-04-20
KR100336229B1 (ko) 2002-05-09
AU8631998A (en) 1999-02-16
CA2296637A1 (en) 1999-02-04
ZA986475B (en) 2000-01-21
NZ502136A (en) 2002-05-31
EP1000027A1 (en) 2000-05-17
PT1000027E (pt) 2003-07-31
DE69812964T2 (de) 2004-03-04
HRP980406A2 (en) 1999-04-30
WO1999005105A1 (en) 1999-02-04
CZ2000221A3 (cs) 2000-05-17
CN1264366A (zh) 2000-08-23
NO313588B1 (no) 2002-10-28
IL133677A0 (en) 2001-04-30
EP0893440A1 (en) 1999-01-27
CA2296637C (en) 2005-11-15
MY117734A (en) 2004-07-31
HUP0003198A2 (en) 2001-03-28
CZ296947B6 (cs) 2006-08-16
HK1029339A1 (en) 2001-03-30
HUP0003198A3 (en) 2002-10-28
PE96999A1 (es) 1999-10-12
TR200000148T2 (tr) 2000-07-21
NO20000301L (no) 2000-01-21
PL191602B1 (pl) 2006-06-30
AU740453B2 (en) 2001-11-01
SI1000027T1 (en) 2003-10-31
UY25108A1 (es) 2000-12-29
AR015133A1 (es) 2001-04-18
CN1125047C (zh) 2003-10-22
NO20000301D0 (no) 2000-01-21
IL133677A (en) 2004-06-01

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