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WO2009038104A1 - 低結合性固相表面の作製方法 - Google Patents

低結合性固相表面の作製方法 Download PDF

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Publication number
WO2009038104A1
WO2009038104A1 PCT/JP2008/066792 JP2008066792W WO2009038104A1 WO 2009038104 A1 WO2009038104 A1 WO 2009038104A1 JP 2008066792 W JP2008066792 W JP 2008066792W WO 2009038104 A1 WO2009038104 A1 WO 2009038104A1
Authority
WO
WIPO (PCT)
Prior art keywords
solid phase
low binding
production
binding property
phase surface
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/066792
Other languages
English (en)
French (fr)
Inventor
Tadahito Takahashi
Nao Arikuni
Toshiya Oki
Mami Heichi
Masaya Kurokawa
Ryo Hisano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NANOBIOTECH CO Ltd
Starlite Co Ltd
Original Assignee
NANOBIOTECH CO Ltd
Starlite Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NANOBIOTECH CO Ltd, Starlite Co Ltd filed Critical NANOBIOTECH CO Ltd
Publication of WO2009038104A1 publication Critical patent/WO2009038104A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)

Abstract

本発明は、タンパク質含む生体試料を用いる実験に使用する器具類を構成する素材表面に対する、有機物の非特異的吸着防止方法を提供することを課題とする。この方法は、固相表面を酸化処理して、含酸素官能基を導入する工程と、処理表面を化学的に活性化し、表面を反応性にした後、該表面と反応し得るポリアルキレングリコール誘導体、またはポリペプチドにより処理する工程を含む方法により、表面を低結合性にするという表面処理方法を提供する。
PCT/JP2008/066792 2007-09-18 2008-09-17 低結合性固相表面の作製方法 Ceased WO2009038104A1 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-241618 2007-09-18
JP2007241618A JP2011033341A (ja) 2007-09-18 2007-09-18 低結合性固相表面の作製方法

Publications (1)

Publication Number Publication Date
WO2009038104A1 true WO2009038104A1 (ja) 2009-03-26

Family

ID=40467914

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/066792 Ceased WO2009038104A1 (ja) 2007-09-18 2008-09-17 低結合性固相表面の作製方法

Country Status (2)

Country Link
JP (1) JP2011033341A (ja)
WO (1) WO2009038104A1 (ja)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009189267A (ja) * 2008-02-13 2009-08-27 Nissui Pharm Co Ltd 微小ウェル内に分配するための容器
JP2014048278A (ja) * 2012-09-04 2014-03-17 Jsr Corp 無機材料で構成される表面用の表面処理剤、該表面処理剤でコーティングされた器具、その製造方法、及び新規重合体
JP2014153140A (ja) * 2013-02-07 2014-08-25 Jsr Corp ブロッキング剤、標的物質に対する抗原または抗体が固定化された担体、これを含む体外診断用試薬およびキット、並びに標的物質の検出方法
JP2016222938A (ja) * 2016-10-06 2016-12-28 Jsr株式会社 無機材料で構成される表面用の表面処理剤、該表面処理剤でコーティングされた器具、その製造方法、及び新規重合体
CN119023952A (zh) * 2024-08-30 2024-11-26 重庆大学 一种提高丙烯酸酯基底生物分子偶联效率的方法

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023042859A1 (ja) * 2021-09-15 2023-03-23 株式会社幹細胞＆デバイス研究所 細胞群運動特性測定方法、細胞群測定デバイス
EP4481384A1 (en) * 2022-02-18 2024-12-25 PHC Corporation Nonspecific reaction inhibitor

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004102194A1 (ja) * 2003-05-19 2004-11-25 Toray Industries, Inc. 選択結合性物質固定化担体
JP2006308307A (ja) * 2005-04-26 2006-11-09 Toyo Kohan Co Ltd 生体関連分子の非特異的吸着を阻害する方法および生体関連分子検出用キット

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004102194A1 (ja) * 2003-05-19 2004-11-25 Toray Industries, Inc. 選択結合性物質固定化担体
JP2006308307A (ja) * 2005-04-26 2006-11-09 Toyo Kohan Co Ltd 生体関連分子の非特異的吸着を阻害する方法および生体関連分子検出用キット

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009189267A (ja) * 2008-02-13 2009-08-27 Nissui Pharm Co Ltd 微小ウェル内に分配するための容器
JP2014048278A (ja) * 2012-09-04 2014-03-17 Jsr Corp 無機材料で構成される表面用の表面処理剤、該表面処理剤でコーティングされた器具、その製造方法、及び新規重合体
JP2014153140A (ja) * 2013-02-07 2014-08-25 Jsr Corp ブロッキング剤、標的物質に対する抗原または抗体が固定化された担体、これを含む体外診断用試薬およびキット、並びに標的物質の検出方法
JP2016222938A (ja) * 2016-10-06 2016-12-28 Jsr株式会社 無機材料で構成される表面用の表面処理剤、該表面処理剤でコーティングされた器具、その製造方法、及び新規重合体
CN119023952A (zh) * 2024-08-30 2024-11-26 重庆大学 一种提高丙烯酸酯基底生物分子偶联效率的方法

Also Published As

Publication number Publication date
JP2011033341A (ja) 2011-02-17

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