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WO2008102639A1 - グルコースの電気化学的定量方法、グルコース脱水素酵素組成物、及び、グルコース測定用電気化学センサー - Google Patents

グルコースの電気化学的定量方法、グルコース脱水素酵素組成物、及び、グルコース測定用電気化学センサー Download PDF

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Publication number
WO2008102639A1
WO2008102639A1 PCT/JP2008/051850 JP2008051850W WO2008102639A1 WO 2008102639 A1 WO2008102639 A1 WO 2008102639A1 JP 2008051850 W JP2008051850 W JP 2008051850W WO 2008102639 A1 WO2008102639 A1 WO 2008102639A1
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WIPO (PCT)
Prior art keywords
glucose
electrochemical
quantification
determination
dehydrogenase composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/051850
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English (en)
French (fr)
Inventor
Kazuki Inamori
Masao Kitabayashi
Yuji Tsuji
Yoshiaki Nishiya
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Toyobo Co Ltd
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Toyobo Co Ltd
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Priority to JP2009500128A priority Critical patent/JPWO2008102639A1/ja
Publication of WO2008102639A1 publication Critical patent/WO2008102639A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
    • C12Q1/006—Enzyme electrodes involving specific analytes or enzymes for glucose
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/37—Assays involving biological materials from specific organisms or of a specific nature from fungi
    • G01N2333/38—Assays involving biological materials from specific organisms or of a specific nature from fungi from Aspergillus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

　フラビン化合物を補酵素として必要とするグルコース脱水素酵素を用いて、ポテンショメトリーによる電位測定を行うことを特徴とする溶液中のグルコースの定量方法であり、糸状菌由来で、特にアスペルギルス・オリゼ（Ａｓｐｅｒｇｉｌｌｕｓ　ｏｒｙｚａｅ）、または、アスペルギルス・テレウス（Ａｓｐｅｒｇｉｌｌｕｓ　ｔｅｒｒｅｕｓ）由来のグルコース脱水素酵素を用いて定量する事が好ましい。
PCT/JP2008/051850 2007-02-20 2008-02-05 グルコースの電気化学的定量方法、グルコース脱水素酵素組成物、及び、グルコース測定用電気化学センサー Ceased WO2008102639A1 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2009500128A JPWO2008102639A1 (ja) 2007-02-20 2008-02-05 グルコースの電気化学的定量方法、グルコース脱水素酵素組成物、及び、グルコース測定用電気化学センサー

Applications Claiming Priority (16)

Application Number Priority Date Filing Date Title
JP2007039133 2007-02-20
JP2007-039133 2007-02-20
JP2007075022 2007-03-22
JP2007-075022 2007-03-22
JP2007-075023 2007-03-22
JP2007075023 2007-03-22
US90885207P 2007-03-29 2007-03-29
US60/908,852 2007-03-29
JP2007118423 2007-04-27
JP2007-118423 2007-04-27
JP2007-132488 2007-05-18
JP2007132488 2007-05-18
JP2007313048 2007-12-04
JP2007-313047 2007-12-04
JP2007-313048 2007-12-04
JP2007313047 2007-12-04

Publications (1)

Publication Number Publication Date
WO2008102639A1 true WO2008102639A1 (ja) 2008-08-28

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PCT/JP2008/051850 Ceased WO2008102639A1 (ja) 2007-02-20 2008-02-05 グルコースの電気化学的定量方法、グルコース脱水素酵素組成物、及び、グルコース測定用電気化学センサー

Country Status (3)

Country Link
US (1) US20080248514A1 (ja)
JP (1) JPWO2008102639A1 (ja)
WO (1) WO2008102639A1 (ja)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009119728A1 (ja) * 2008-03-27 2009-10-01 東洋紡績株式会社 糸状菌由来フラビンアデニンジヌクレオチド依存性グルコースデヒドロゲナーゼ（ｆａｄｇｄｈ）
WO2010053161A1 (ja) * 2008-11-06 2010-05-14 ユニチカ株式会社 改変型フラビンアデニンジヌクレオチド依存性グルコースデヒドロゲナーゼ
WO2011034108A1 (ja) * 2009-09-16 2011-03-24 東洋紡績株式会社 改変型フラビンアデニンジヌクレオチド依存性グルコースデヒドロゲナーゼ
JP2011097931A (ja) * 2009-10-09 2011-05-19 Toyobo Co Ltd Ｆａｄジヌクレオチド依存性グルコースデヒドロゲナーゼの温度依存性を改善する方法
JP2013083587A (ja) * 2011-10-12 2013-05-09 Nipro Corp 生体試料測定装置及び測定方法
JP2015519892A (ja) * 2012-05-03 2015-07-16 エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト グリコシル化されている修飾フラビンアデニンジヌクレオチド依存性グルコース脱水素酵素
JP2020022913A (ja) * 2016-04-27 2020-02-13 Ｐｈｃホールディングス株式会社 バイオセンサ
CN113552198A (zh) * 2021-05-31 2021-10-26 武汉维尔博生物科技有限公司 一种基于高响应葡萄糖适配体的电化学传感器及其制备方法
KR20230089187A (ko) * 2021-12-13 2023-06-20 대한민국(농촌진흥청장) 저밀도 폴리에틸렌을 이용 및 산화하는 곰팡이 아스퍼질러스 오리제 58-11 kacc 83054bp 및 이의 용도

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CA2511656A1 (en) * 2002-12-24 2004-07-15 Ikeda Food Research Co., Ltd. Coenzyme-binding glucose dehydrogenase
EP2380980B1 (en) 2005-03-25 2014-11-05 Ikeda Food Research Co. Ltd. Coenzyme-linked glucose dehydrogenase and polynucleotide encoding the same
WO2008059777A1 (en) * 2006-11-14 2008-05-22 Toyo Boseki Kabushiki Kaisha Modified flavine-adenine-dinucleotide-dependent glucose dehydrogenase
US20130092536A1 (en) 2010-07-23 2013-04-18 Roche Diagnostics Operations, Inc. Zwitterion buffer containing compositions and uses in electroanalytical methods
JP5584740B2 (ja) * 2011-09-26 2014-09-03 アークレイ株式会社 グルコースセンサ
WO2014025908A1 (en) 2012-08-07 2014-02-13 Bio-Rad Laboratories, Inc. Modified electrode buffers for stain-free protein detection in electrophoresis
US10793820B2 (en) * 2013-04-30 2020-10-06 Lawrence Livermore National Security, Llc Miniaturized, automated in-vitro tissue bioreactor
GB2539224A (en) * 2015-06-09 2016-12-14 Giuseppe Occhipinti Luigi Method of forming a chemical sensor device and device
US10365242B2 (en) * 2017-10-04 2019-07-30 King Fahd University Of Petroleum And Minerals Electrochemical cell for detecting hydroquinone
CN113588935A (zh) * 2021-07-12 2021-11-02 成都云芯医联科技有限公司 一种电化学免条码血糖试纸及其制备方法
CN115201308B (zh) * 2022-07-18 2024-01-26 山东省医疗器械和药品包装检验研究院 一种持续葡萄糖监测系统稳定性评价系统及方法

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Patent Citations (4)

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JPH01203962A (ja) * 1988-02-10 1989-08-16 Nec Corp 免疫化学的測定法
JPH0622793A (ja) * 1990-07-19 1994-02-01 Miles Inc 導電センサーおよびそれらの診断用検定への使用
JP2001252095A (ja) * 2000-03-14 2001-09-18 Asahi Kasei Corp 微量成分の測定法及びそれに用いる組成物
WO2004058958A1 (ja) * 2002-12-24 2004-07-15 Ikeda Food Research Co., Ltd. 補酵素結合型グルコース脱水素酵素

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Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009119728A1 (ja) * 2008-03-27 2009-10-01 東洋紡績株式会社 糸状菌由来フラビンアデニンジヌクレオチド依存性グルコースデヒドロゲナーゼ（ｆａｄｇｄｈ）
WO2010053161A1 (ja) * 2008-11-06 2010-05-14 ユニチカ株式会社 改変型フラビンアデニンジヌクレオチド依存性グルコースデヒドロゲナーゼ
WO2011034108A1 (ja) * 2009-09-16 2011-03-24 東洋紡績株式会社 改変型フラビンアデニンジヌクレオチド依存性グルコースデヒドロゲナーゼ
US8247189B2 (en) 2009-09-16 2012-08-21 Toyo Boseki Kabushiki Kaisha Modified flavin adenine dinucleotide-dependent glucose dehydrogenase
JP2011097931A (ja) * 2009-10-09 2011-05-19 Toyobo Co Ltd Ｆａｄジヌクレオチド依存性グルコースデヒドロゲナーゼの温度依存性を改善する方法
JP2013083587A (ja) * 2011-10-12 2013-05-09 Nipro Corp 生体試料測定装置及び測定方法
JP2015519892A (ja) * 2012-05-03 2015-07-16 エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト グリコシル化されている修飾フラビンアデニンジヌクレオチド依存性グルコース脱水素酵素
EP2844747B1 (en) * 2012-05-03 2019-03-20 Roche Diabetes Care GmbH A glycosylated modified flavin adenine dinucleotide dependent glucose dehydrogenase
JP2020022913A (ja) * 2016-04-27 2020-02-13 Ｐｈｃホールディングス株式会社 バイオセンサ
US11369412B2 (en) 2016-04-27 2022-06-28 Phc Holdings Corporation Sensor insertion device and biosensor
CN113552198A (zh) * 2021-05-31 2021-10-26 武汉维尔博生物科技有限公司 一种基于高响应葡萄糖适配体的电化学传感器及其制备方法
CN113552198B (zh) * 2021-05-31 2024-03-26 武汉维尔博生物科技有限公司 一种基于高响应葡萄糖适配体的电化学传感器及其制备方法
KR20230089187A (ko) * 2021-12-13 2023-06-20 대한민국(농촌진흥청장) 저밀도 폴리에틸렌을 이용 및 산화하는 곰팡이 아스퍼질러스 오리제 58-11 kacc 83054bp 및 이의 용도
KR102763026B1 (ko) 2021-12-13 2025-02-11 대한민국 저밀도 폴리에틸렌을 이용 및 산화하는 곰팡이 아스퍼질러스 오리제 58-11 kacc 83054bp 및 이의 용도

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JPWO2008102639A1 (ja) 2010-05-27

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