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WO2008155998A1 - 抗不安抗うつ剤 - Google Patents

抗不安抗うつ剤 Download PDF

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Publication number
WO2008155998A1
WO2008155998A1 PCT/JP2008/060477 JP2008060477W WO2008155998A1 WO 2008155998 A1 WO2008155998 A1 WO 2008155998A1 JP 2008060477 W JP2008060477 W JP 2008060477W WO 2008155998 A1 WO2008155998 A1 WO 2008155998A1
Authority
WO
WIPO (PCT)
Prior art keywords
antianxiety
antidepressant
antidepressant agent
activity
agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/060477
Other languages
English (en)
French (fr)
Inventor
Eiji Takeda
Junji Terao
Hiroyoshi Sei
Hiroyuki Sakakibara
Kazuyoshi Kitaoka
Toshitsugu Miyazaki
Chieko Kitajima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nagase and Co Ltd
University of Tokushima NUC
Original Assignee
Nagase and Co Ltd
University of Tokushima NUC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nagase and Co Ltd, University of Tokushima NUC filed Critical Nagase and Co Ltd
Priority to JP2009520423A priority Critical patent/JPWO2008155998A1/ja
Publication of WO2008155998A1 publication Critical patent/WO2008155998A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Psychiatry (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Pain & Pain Management (AREA)
  • Mycology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Fodder In General (AREA)

Abstract

　十分な抗不安作用および／または抗うつ作用を有する抗不安抗うつ剤、および該抗不安抗うつ剤を含有する飲食物を提供する。 　本発明の抗不安抗うつ剤は、醗酵人参エキスおよび／または該醗酵人参エキスから得られる成分を有効成分として含有する。また、本発明は、該抗不安抗うつ剤を含有し、抗不安抗うつ作用を有することを特徴とする、不安症もしくはうつ症の予防または治療のために用いられる旨の表示を付した飲食物にも関する。
PCT/JP2008/060477 2007-06-21 2008-06-06 抗不安抗うつ剤 Ceased WO2008155998A1 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2009520423A JPWO2008155998A1 (ja) 2007-06-21 2008-06-06 抗不安抗うつ剤

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2007164034 2007-06-21
JP2007-164183 2007-06-21
JP2007164183 2007-06-21
JP2007-164034 2007-06-21

Publications (1)

Publication Number Publication Date
WO2008155998A1 true WO2008155998A1 (ja) 2008-12-24

Family

ID=40156157

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/060477 Ceased WO2008155998A1 (ja) 2007-06-21 2008-06-06 抗不安抗うつ剤

Country Status (2)

Country Link
JP (1) JPWO2008155998A1 (ja)
WO (1) WO2008155998A1 (ja)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011121926A (ja) * 2009-12-14 2011-06-23 Lion Corp プロトパナキサトリオール及びプロトパナキサジオール含有組成物
CN102145006A (zh) * 2010-02-09 2011-08-10 张作光 人参皂甙Ppt的抗抑郁用途
JP2013529899A (ja) * 2010-05-14 2013-07-25 株式会社ジーシーエイチアンドピー ジンセノサイド成分を増加させた新規な加工人参または加工人参抽出物の製造方法
JP2015168614A (ja) * 2014-03-04 2015-09-28 長瀬産業株式会社 Ｇｌｐ−１分泌促進剤
JP2016508489A (ja) * 2013-01-31 2016-03-22 シャンハイ イノベーティブ リサーチ センター オブ トラディショナル チャイニーズ メディスン プロトパナキサジオール誘導体、その製造方法及びその応用
KR101641509B1 (ko) * 2015-01-22 2016-07-21 샘표 주식회사 아글리콘인 ppd 및/또는 ppt를 유효성분으로 포함하는 항스트레스용 조성물
JP2019524835A (ja) * 2016-08-16 2019-09-05 エムディー ヘルスケア インコーポレイテッドＭｄ Ｈｅａｌｔｈｃａｒｅ Ｉｎｃ． ラクトバチルス属細菌由来小胞を含む精神疾患の予防または治療用組成物
JP2019170246A (ja) * 2018-03-28 2019-10-10 株式会社ナガセビューティケァ 発酵物の製造方法
US10709749B2 (en) 2013-08-30 2020-07-14 Green Cross Wellbeing Corporation Composition for preventing and treating cancer-related fatigue, containing processed ginseng powder or processed ginseng extract having increased ginsenoside constituent

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1099094A (ja) * 1996-09-25 1998-04-21 Happy World:Kk 薬用ニンジンサポニン代謝産物の製造法
JP2004049154A (ja) * 2002-07-23 2004-02-19 Hideo Hasegawa サポニン分解物を含む発酵人参およびその製造方法
JP2005160373A (ja) * 2003-12-02 2005-06-23 Hideo Hasegawa 配糖体分解性プロバイオティクス
JP2006508660A (ja) * 2002-12-05 2006-03-16 ホングリム トレーディング カンパニー リミテッド 人参の乳酸菌発酵物、それを含有する人参ヨーグルト及びそれに利用される乳酸菌の菌株
JP2008000102A (ja) * 2006-06-26 2008-01-10 Bio Ken:Kk ヨーグルト製造用種菌

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1895966A4 (en) * 2005-04-26 2010-01-20 Ko Boong Kyung PROCESS FOR EXTRACTION OF GINSENGNOSID RG2M; PHARMACEUTICAL COMPOSITION WITH GINSENGNOSID RG2, AND ITS USES
CN100438876C (zh) * 2006-06-09 2008-12-03 上海中药创新研究中心 20(s)-原人参二醇在制备抗抑郁药物中的应用

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1099094A (ja) * 1996-09-25 1998-04-21 Happy World:Kk 薬用ニンジンサポニン代謝産物の製造法
JP2004049154A (ja) * 2002-07-23 2004-02-19 Hideo Hasegawa サポニン分解物を含む発酵人参およびその製造方法
JP2006508660A (ja) * 2002-12-05 2006-03-16 ホングリム トレーディング カンパニー リミテッド 人参の乳酸菌発酵物、それを含有する人参ヨーグルト及びそれに利用される乳酸菌の菌株
JP2005160373A (ja) * 2003-12-02 2005-06-23 Hideo Hasegawa 配糖体分解性プロバイオティクス
JP2008000102A (ja) * 2006-06-26 2008-01-10 Bio Ken:Kk ヨーグルト製造用種菌

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
HASEGAWA H.: "Kanpo to Probiotic", IGAKU NO AYUMI, vol. 207, no. 10, 2003, pages 857 - 861 *
PARK J.-H. ET AL.: "Anxiolytic-like effects of ginseng in the elevated plus-maze model: Comparison of red dinseng and sun ginseng", PROGRESS IN NEURO-PSYCHOPHARMACOLOGY AND BIOLOGICAL PSYCHIATRY, vol. 29, no. 6, July 2005 (2005-07-01), pages 895 - 900 *
TACHIKAWA E. ET AL.: "In vitro inhibition of adrenal catecholamine secretion by steroidal metabolites of ginseng saponins", BIOCHEMICAL PHARMACOLOGY, vol. 66, no. 11, 2003, pages 2213 - 2221 *
WEI X.-Y. ET AL.: "Anxiolytic effect of saponins from Panax quinquefolium in mice", J. ETHNOPHARMACOL., vol. 111, no. 3, 22 May 2007 (2007-05-22), pages 613 - 618 *

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011121926A (ja) * 2009-12-14 2011-06-23 Lion Corp プロトパナキサトリオール及びプロトパナキサジオール含有組成物
CN102145006A (zh) * 2010-02-09 2011-08-10 张作光 人参皂甙Ppt的抗抑郁用途
JP2013529899A (ja) * 2010-05-14 2013-07-25 株式会社ジーシーエイチアンドピー ジンセノサイド成分を増加させた新規な加工人参または加工人参抽出物の製造方法
US9512453B2 (en) 2010-05-14 2016-12-06 Green Cross Wellbeing Corporation Method for preparing novel processed ginseng or an extract thereof, the usually minute ginsenoside content of which is increased
JP2016508489A (ja) * 2013-01-31 2016-03-22 シャンハイ イノベーティブ リサーチ センター オブ トラディショナル チャイニーズ メディスン プロトパナキサジオール誘導体、その製造方法及びその応用
US10709749B2 (en) 2013-08-30 2020-07-14 Green Cross Wellbeing Corporation Composition for preventing and treating cancer-related fatigue, containing processed ginseng powder or processed ginseng extract having increased ginsenoside constituent
US11464821B2 (en) 2013-08-30 2022-10-11 Green Cross Wellbeing Corporation Composition for reducing cancer cachexia or weight loss caused by anticancer drug therapy or radiation therapy comprising ginseng extract having increased ginsenoside Rg3 and Rh2
JP2015168614A (ja) * 2014-03-04 2015-09-28 長瀬産業株式会社 Ｇｌｐ−１分泌促進剤
KR101641509B1 (ko) * 2015-01-22 2016-07-21 샘표 주식회사 아글리콘인 ppd 및/또는 ppt를 유효성분으로 포함하는 항스트레스용 조성물
EP3501527A4 (en) * 2016-08-16 2020-05-06 MD Healthcare Inc. COMPOSITION FOR PREVENTING OR TREATING MENTAL DISORDERS WITH LACTOBACILLUS
JP2019524835A (ja) * 2016-08-16 2019-09-05 エムディー ヘルスケア インコーポレイテッドＭｄ Ｈｅａｌｔｈｃａｒｅ Ｉｎｃ． ラクトバチルス属細菌由来小胞を含む精神疾患の予防または治療用組成物
US11583559B2 (en) 2016-08-16 2023-02-21 Md Healthcare Inc. Composition for preventing or treating mental disorder, containing Lactobacillus sp. bacteria-derived vesicle
JP2019170246A (ja) * 2018-03-28 2019-10-10 株式会社ナガセビューティケァ 発酵物の製造方法

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