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WO2008019782A3 - Dispersionen von nanoharnstoffen. enthaltend wirkstoffe - Google Patents

Dispersionen von nanoharnstoffen. enthaltend wirkstoffe Download PDF

Info

Publication number
WO2008019782A3
WO2008019782A3 PCT/EP2007/006989 EP2007006989W WO2008019782A3 WO 2008019782 A3 WO2008019782 A3 WO 2008019782A3 EP 2007006989 W EP2007006989 W EP 2007006989W WO 2008019782 A3 WO2008019782 A3 WO 2008019782A3
Authority
WO
WIPO (PCT)
Prior art keywords
nanoureas
dispersions
active ingredients
containing active
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2007/006989
Other languages
English (en)
French (fr)
Other versions
WO2008019782A2 (de
Inventor
Sebastian Doerr
Michael Mager
Burkhard Koehler
Heike Heckroth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Covestro Deutschland AG
Original Assignee
Bayer MaterialScience AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer MaterialScience AG filed Critical Bayer MaterialScience AG
Priority to EP07801542A priority Critical patent/EP2054098A2/de
Priority to JP2009524930A priority patent/JP2010501016A/ja
Priority to BRPI0716049-6A2A priority patent/BRPI0716049A2/pt
Publication of WO2008019782A2 publication Critical patent/WO2008019782A2/de
Publication of WO2008019782A3 publication Critical patent/WO2008019782A3/de
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08—Materials for coatings
    • A61L29/085—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/08—Processes
    • C08G18/0804—Manufacture of polymers containing ionic or ionogenic groups
    • C08G18/0819—Manufacture of polymers containing ionic or ionogenic groups containing anionic or anionogenic groups
    • C08G18/0823—Manufacture of polymers containing ionic or ionogenic groups containing anionic or anionogenic groups containing carboxylate salt groups or groups forming them
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/70—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
    • C08G18/72—Polyisocyanates or polyisothiocyanates
    • C08G18/73—Polyisocyanates or polyisothiocyanates acyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/12—Nanosized materials, e.g. nanofibres, nanoparticles, nanowires, nanotubes; Nanostructured surfaces

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Manufacturing & Machinery (AREA)
  • Transplantation (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Medicinal Preparation (AREA)
  • Paints Or Removers (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • General Preparation And Processing Of Foods (AREA)

Abstract

Die vorliegende Erfindung betrifft Dispersionen von Nanoharnstoffen enthaltend Wirkstoffe, ein Verfahren zu deren Herstellung, sowie deren Verwendung.
PCT/EP2007/006989 2006-08-18 2007-08-08 Dispersionen von nanoharnstoffen. enthaltend wirkstoffe Ceased WO2008019782A2 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP07801542A EP2054098A2 (de) 2006-08-18 2007-08-08 Dispersionen von nanoharnstoffen. enthaltend wirkstoffe
JP2009524930A JP2010501016A (ja) 2006-08-18 2007-08-08 活性成分を含有するナノ尿素の分散液
BRPI0716049-6A2A BRPI0716049A2 (pt) 2006-08-18 2007-08-08 dispersÕes de nanourÉias, contendo substÂncias ativas

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102006038940.9 2006-08-18
DE102006038940A DE102006038940A1 (de) 2006-08-18 2006-08-18 Dispersionen von Nanoharnstoffen, enthaltend Wirkstoffe

Publications (2)

Publication Number Publication Date
WO2008019782A2 WO2008019782A2 (de) 2008-02-21
WO2008019782A3 true WO2008019782A3 (de) 2009-02-12

Family

ID=38738912

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2007/006989 Ceased WO2008019782A2 (de) 2006-08-18 2007-08-08 Dispersionen von nanoharnstoffen. enthaltend wirkstoffe

Country Status (8)

Country Link
US (2) US20080044474A1 (de)
EP (1) EP2054098A2 (de)
JP (1) JP2010501016A (de)
CN (1) CN101505808A (de)
BR (1) BRPI0716049A2 (de)
DE (1) DE102006038940A1 (de)
RU (1) RU2009109578A (de)
WO (1) WO2008019782A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006038940A1 (de) * 2006-08-18 2008-02-21 Bayer Materialscience Ag Dispersionen von Nanoharnstoffen, enthaltend Wirkstoffe
EP2103316A1 (de) * 2008-03-20 2009-09-23 Bayer MaterialScience AG Hydrophile Polyurethandispersionen
EP2108383A1 (de) * 2008-04-08 2009-10-14 Bayer MaterialScience AG Medizinische Geräte mit einer antibakteriellen Polyurethanharnstoffbeschichtung
EP2108382A1 (de) * 2008-04-08 2009-10-14 Bayer MaterialScience AG Silberhaltige Polyurethanharnstofflösung
DE102008025613A1 (de) * 2008-05-28 2009-12-03 Bayer Materialscience Ag Hydrophile Polyurethanbeschichtungen
TWI392697B (zh) * 2008-05-30 2013-04-11 Univ Nat Chunghsing The silver particle-containing aqueous polyurethane pot synthesis of
US8791200B2 (en) 2008-09-04 2014-07-29 Bayer Materialscience Ag TCD based hydrophilic polyurethane dispersions
EP2687552A1 (de) * 2012-07-17 2014-01-22 Huntsman International Llc Verwendung von Polyharnstoff-Nanopartikeln als Leistungsmodifikatoren in Polyurethanmaterialien

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1264812A2 (de) * 2001-06-05 2002-12-11 COMPO GmbH & Co.KG Düngemittel mit verzögerter Freisetzung und Verfahren zu dessen Herstellung.
WO2003082459A1 (fr) * 2002-03-28 2003-10-09 Centre National De La Recherche Scientifique (Cnrs) Capsules composites biocompatibles
US6875448B1 (en) * 1999-09-03 2005-04-05 Chugai Seiyaku Kabushiki Kaisha Method of intracellular sustained-release of drug and preparations

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2627073C2 (de) * 1976-06-16 1983-12-29 Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung von stabilen Dispersionen
GB1598451A (en) * 1977-01-17 1981-09-23 Netherlands Central Org Scient Antifungal and/or antibacterial organotin compounds there preparation and uses
US4581028A (en) * 1984-04-30 1986-04-08 The Trustees Of Columbia University In The City Of New York Infection-resistant materials and method of making same through use of sulfonamides
FI95816C (fi) * 1989-05-04 1996-03-25 Ad Tech Holdings Ltd Antimikrobinen esine ja menetelmä sen valmistamiseksi
US5320908A (en) * 1989-05-04 1994-06-14 Ad Tech Holdings Limited Deposition of an extremely thin silver layer on a nonconducting substrate
JPH0859770A (ja) * 1994-08-15 1996-03-05 Dainippon Ink & Chem Inc ポリウレタンポリ尿素架橋微粒子分散体及びその製造方法
GB9502253D0 (en) * 1995-02-06 1995-03-29 Giltech Ltd The effects of antibacterial agents on the behaviour of mouse fibroblasts in vitro
US6395292B2 (en) * 1996-02-02 2002-05-28 Alza Corporation Sustained delivery of an active agent using an implantable system
US6132420A (en) * 1996-02-02 2000-10-17 Alza Corporation Osmotic delivery system and method for enhancing start-up and performance of osmotic delivery systems
EP0877599B1 (de) * 1996-02-02 2003-03-26 Alza Corporation Implantierbares system mit verzögerter freisetzung von leuprolid
US6020004A (en) * 1997-04-17 2000-02-01 Amgen Inc. Biodegradable microparticles for the sustained delivery of therapeutic drugs
US6224579B1 (en) * 1999-03-31 2001-05-01 The Trustees Of Columbia University In The City Of New York Triclosan and silver compound containing medical devices
CN1429239A (zh) * 2000-05-16 2003-07-09 陶氏环球技术公司 聚氨酯分散系及其制备的膜
US7357949B2 (en) * 2001-12-21 2008-04-15 Agion Technologies Inc. Encapsulated inorganic antimicrobial additive for controlled release
DE10226932A1 (de) * 2002-06-17 2003-12-24 Bayer Ag Strahlenhärtende Beschichtungsmittel
DE10360368A1 (de) * 2003-12-22 2005-07-21 Bayer Materialscience Ag Dispersionen
DE102006038940A1 (de) * 2006-08-18 2008-02-21 Bayer Materialscience Ag Dispersionen von Nanoharnstoffen, enthaltend Wirkstoffe

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6875448B1 (en) * 1999-09-03 2005-04-05 Chugai Seiyaku Kabushiki Kaisha Method of intracellular sustained-release of drug and preparations
EP1264812A2 (de) * 2001-06-05 2002-12-11 COMPO GmbH & Co.KG Düngemittel mit verzögerter Freisetzung und Verfahren zu dessen Herstellung.
WO2003082459A1 (fr) * 2002-03-28 2003-10-09 Centre National De La Recherche Scientifique (Cnrs) Capsules composites biocompatibles

Also Published As

Publication number Publication date
WO2008019782A2 (de) 2008-02-21
EP2054098A2 (de) 2009-05-06
US20080044474A1 (en) 2008-02-21
BRPI0716049A2 (pt) 2013-09-17
CN101505808A (zh) 2009-08-12
DE102006038940A1 (de) 2008-02-21
RU2009109578A (ru) 2010-09-27
US20100034861A1 (en) 2010-02-11
JP2010501016A (ja) 2010-01-14

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