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WO1997004099A3 - Papillomviren, mittel zu deren nachweis sowie zur therapie von durch sie verursachten erkrankungen - Google Patents

Papillomviren, mittel zu deren nachweis sowie zur therapie von durch sie verursachten erkrankungen Download PDF

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Publication number
WO1997004099A3
WO1997004099A3 PCT/DE1996/001369 DE9601369W WO9704099A3 WO 1997004099 A3 WO1997004099 A3 WO 1997004099A3 DE 9601369 W DE9601369 W DE 9601369W WO 9704099 A3 WO9704099 A3 WO 9704099A3
Authority
WO
WIPO (PCT)
Prior art keywords
papillomaviruses
viruses
agents
detecting
diseases caused
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/DE1996/001369
Other languages
English (en)
French (fr)
Other versions
WO1997004099A2 (de
Inventor
Vladimir Shamanin
Villiers-Zur Hausen Ethel-M De
Hausen Harald Zur
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Deutsches Krebsforschungszentrum DKFZ
Original Assignee
Deutsches Krebsforschungszentrum DKFZ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Deutsches Krebsforschungszentrum DKFZ filed Critical Deutsches Krebsforschungszentrum DKFZ
Priority to US09/000,266 priority Critical patent/US6322795B1/en
Priority to EP96928326A priority patent/EP0839199A1/de
Priority to JP9506174A priority patent/JPH11512925A/ja
Publication of WO1997004099A2 publication Critical patent/WO1997004099A2/de
Anticipated expiration legal-status Critical
Priority to US09/628,099 priority patent/US6368832B1/en
Publication of WO1997004099A3 publication Critical patent/WO1997004099A3/de
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/20011Papillomaviridae
    • C12N2710/20022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Die Erfindung betrifft eine für ein Peptid eines Papillomvirus-Hauptcapsid-Proteins codierende DNA. Ferner betrifft die Erfindung ein eine solche DNA enthaltendes Papillomvirus-Genom. Des weiteren betrifft die Erfindung durch das Papillomvirus-Genom codierte Proteine und Virus-ähnliche Partikel sowie gegen sie gerichtete Antikörper und deren Verwendung in Diagnose, Therapie und Vakzinierung.
PCT/DE1996/001369 1995-07-19 1996-07-19 Papillomviren, mittel zu deren nachweis sowie zur therapie von durch sie verursachten erkrankungen Ceased WO1997004099A2 (de)

Priority Applications (4)

Application Number Priority Date Filing Date Title
US09/000,266 US6322795B1 (en) 1995-07-19 1996-07-19 Papilloma viruses, agents for detecting them and for treating diseases caused by such viruses
EP96928326A EP0839199A1 (de) 1995-07-19 1996-07-19 Papillomviren, mittel zu deren nachweis sowie zur therapie von durch sie verursachten erkrankungen
JP9506174A JPH11512925A (ja) 1995-07-19 1996-07-19 パピローマウイルス、その検出用製品及びそれにより生ずる疾病の治療用製品
US09/628,099 US6368832B1 (en) 1995-07-19 2000-05-25 Papilloma viruses, agents for detecting them and for treating diseases caused by such viruses

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19526386A DE19526386C1 (de) 1995-07-19 1995-07-19 Papillomviren, Mittel zu deren Nachweis sowie zur Therapie von durch sie verursachten Erkrankungen
DE19526386.3 1995-07-19

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US09/000,266 A-371-Of-International US6322795B1 (en) 1995-07-19 1996-07-19 Papilloma viruses, agents for detecting them and for treating diseases caused by such viruses
US09/628,099 Division US6368832B1 (en) 1995-07-19 2000-05-25 Papilloma viruses, agents for detecting them and for treating diseases caused by such viruses

Publications (2)

Publication Number Publication Date
WO1997004099A2 WO1997004099A2 (de) 1997-02-06
WO1997004099A3 true WO1997004099A3 (de) 2001-04-12

Family

ID=7767261

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE1996/001369 Ceased WO1997004099A2 (de) 1995-07-19 1996-07-19 Papillomviren, mittel zu deren nachweis sowie zur therapie von durch sie verursachten erkrankungen

Country Status (5)

Country Link
US (4) US6322795B1 (de)
EP (1) EP0839199A1 (de)
JP (1) JPH11512925A (de)
DE (1) DE19526386C1 (de)
WO (1) WO1997004099A2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19648962C1 (de) * 1996-11-26 1998-02-26 Deutsches Krebsforsch Papillomviren, Mittel zu deren Nachweis sowie zur Therapie von durch sie verursachten Erkrankungen
DE19712541C1 (de) * 1997-03-25 1998-11-05 Deutsches Krebsforsch Papillomviren, Mittel zu deren Nachweis sowie zur Therapie von durch sie verursachten Erkrankungen
DE19735118C1 (de) * 1997-08-13 1998-08-13 Deutsches Krebsforsch Papillomviren, Mittel zu deren Nachweis sowie zur Therapie von durch sie verursachten Erkrankungen
EP1421095B1 (de) * 2001-08-31 2013-10-09 Gen-Probe Incorporated Assay zum nachweis der nukleinsäure des humanen parvovirus b19
KR101514463B1 (ko) 2005-06-08 2015-04-28 다나-파버 캔서 인스티튜트 인크. 예정 세포사 1(pd-1) 경로를 억제함으로써 지속 감염 및 암을 치료하기 위한 방법 및 조성물
US20100040614A1 (en) 2006-12-27 2010-02-18 Rafi Ahmed Compositions and methods for the treatment of infections and tumors
CA2744449C (en) 2008-11-28 2019-01-29 Emory University Methods for the treatment of infections and tumors
EP2576840B1 (de) 2010-05-25 2018-10-17 QIAGEN Gaithersburg, Inc. Hybrid-capture-assay mit schneller ergebnislieferung und zugehörige strategisch gekürzte sonden
KR20190080825A (ko) 2016-03-21 2019-07-08 다나-파버 캔서 인스티튜트 인크. T-세포 기능소실 상태-특이적 유전자 발현 조절인자 및 그 용도

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0301289A1 (de) * 1987-07-11 1989-02-01 BEHRINGWERKE Aktiengesellschaft Humaner Papillomvirus Typ 41
EP0370625A1 (de) * 1988-10-26 1990-05-30 Georgetown University DNS-Sequenzen des menschlichen Papillomavirus Typ 52 und Verfahren zu ihrer Verwendung
WO1994005792A1 (en) * 1992-09-03 1994-03-17 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Self-assembling recombinant papillomavirus capsid proteins
DE4415743A1 (de) * 1994-05-04 1995-11-09 Deutsches Krebsforsch Papillomviren, Mittel zu deren Nachweis sowie zur Therapie von durch sie verursachten Erkrankungen

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0301289A1 (de) * 1987-07-11 1989-02-01 BEHRINGWERKE Aktiengesellschaft Humaner Papillomvirus Typ 41
EP0370625A1 (de) * 1988-10-26 1990-05-30 Georgetown University DNS-Sequenzen des menschlichen Papillomavirus Typ 52 und Verfahren zu ihrer Verwendung
WO1994005792A1 (en) * 1992-09-03 1994-03-17 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Self-assembling recombinant papillomavirus capsid proteins
DE4415743A1 (de) * 1994-05-04 1995-11-09 Deutsches Krebsforsch Papillomviren, Mittel zu deren Nachweis sowie zur Therapie von durch sie verursachten Erkrankungen

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BROWNE H.M. ET AL.: "Analysis of the L1 gene product of human Papillomavirus Type 16 by expression in a Vaccinia Virus recombinant.", J. GEN. VIROLOGY, vol. 69, 1988, pages 1263 - 1273, XP002023586 *
EGAWA K. ET AL.: "Two novel types of Human Papillomavirus, HPV 63 and HPV 65: Comparisons of their clinical and histological features and DNA sequences to other HPV types.", VIROLOGY, vol. 194, 1993, pages 789 - 799, XP002023584 *
JARRETT W.F.H. ET AL.: "Studies on vaccination against Papillomaviruses:Prophylactic and therapeutic vaccination with recombinant structural protein.", VIROLOGY, vol. 184, 1991, pages 33 - 42, XP002023588 *
SHAMANIN ET AL.: "Specific types of Human Papillomavirus found in benign proliferations and carcinomas of the skin in immunosuppressed patients.", CANCER RESEARCH, vol. 54, 1 September 1994 (1994-09-01), pages 4610 - 4613, XP002023585 *
SHAMANIN V. ET AL.: "Human papillomavirus infections in nonmelanoma skin cancer from renal transplant recipients and nonimmunosuppressed patients.", JOURNAL OF THE NATIONAL CANCER INSTITUTE, vol. 88, no. 12, 19 June 1996 (1996-06-19), pages 802 - 811, XP000616318 *

Also Published As

Publication number Publication date
US6368832B1 (en) 2002-04-09
JPH11512925A (ja) 1999-11-09
US6322795B1 (en) 2001-11-27
EP0839199A1 (de) 1998-05-06
US20020110866A1 (en) 2002-08-15
US6555345B2 (en) 2003-04-29
US6562597B2 (en) 2003-05-13
DE19526386C1 (de) 1997-01-02
WO1997004099A2 (de) 1997-02-06
US20020110865A1 (en) 2002-08-15

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