[go: up one dir, main page]

UY31718A1 - Composiciones farmacéuticas acuosas que contienen complejos de borato y poliol - Google Patents

Composiciones farmacéuticas acuosas que contienen complejos de borato y poliol

Info

Publication number
UY31718A1
UY31718A1 UY031718A UY31718A UY31718A1 UY 31718 A1 UY31718 A1 UY 31718A1 UY 031718 A UY031718 A UY 031718A UY 31718 A UY31718 A UY 31718A UY 31718 A1 UY31718 A1 UY 31718A1
Authority
UY
Uruguay
Prior art keywords
waterproof
pharmaceutical compositions
compositions containing
containing borate
polyol complexes
Prior art date
Application number
UY031718A
Other languages
English (en)
Inventor
Bhagwati P Kabra
Rajni Jani
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41037890&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UY31718(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of UY31718A1 publication Critical patent/UY31718A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
    • A01N59/14—Boron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
    • A01N31/02—Acyclic compounds
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
    • A01N33/02—Amines; Quaternary ammonium compounds
    • A01N33/12—Quaternary ammonium compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Zoology (AREA)
  • Pest Control & Pesticides (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Emergency Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

El presente invento se refiere a la provisión de composiciones oftálmicas de dosis múltiples. Las composiciones poseen actividad antimicrobiana suficiente como para cumplir los requisitos de conservación de la eficacia de la USP así como otras normas de conservación similares (como por ejemplo, de Europa y Japón). Las composiciones incluyen dos polioles diferentes junto con borato, un conservante o ambos.
UY031718A 2008-03-17 2009-03-17 Composiciones farmacéuticas acuosas que contienen complejos de borato y poliol UY31718A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3713708P 2008-03-17 2008-03-17

Publications (1)

Publication Number Publication Date
UY31718A1 true UY31718A1 (es) 2009-08-31

Family

ID=41037890

Family Applications (1)

Application Number Title Priority Date Filing Date
UY031718A UY31718A1 (es) 2008-03-17 2009-03-17 Composiciones farmacéuticas acuosas que contienen complejos de borato y poliol

Country Status (24)

Country Link
US (2) US20090232763A1 (es)
EP (3) EP2308466B1 (es)
JP (1) JP5583111B2 (es)
KR (1) KR101541303B1 (es)
CN (2) CN101959500A (es)
AR (1) AR070887A1 (es)
AU (1) AU2009225931B9 (es)
BR (1) BRPI0909738A2 (es)
CA (1) CA2717679C (es)
CL (1) CL2009000625A1 (es)
CY (1) CY1114712T1 (es)
DE (1) DE202009019116U1 (es)
DK (3) DK2420223T3 (es)
ES (3) ES2443548T5 (es)
HR (1) HRP20131173T4 (es)
MX (1) MX2010009336A (es)
PL (1) PL2254549T5 (es)
PT (1) PT2254549E (es)
RU (1) RU2477631C2 (es)
SI (1) SI2254549T2 (es)
TW (1) TWI498122B (es)
UY (1) UY31718A1 (es)
WO (1) WO2009117242A2 (es)
ZA (1) ZA201005994B (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2420223T3 (da) 2008-03-17 2017-11-06 Novartis Ag Vandige farmaceutiske sammensætninger med borat-polyol-komplekser
US20100087540A1 (en) * 2008-10-07 2010-04-08 R-Tech Ueno, Ltd. Pharmaceutical composition
TWI489997B (zh) * 2009-06-19 2015-07-01 Alcon Res Ltd 含有硼酸－多元醇錯合物之水性藥學組成物
KR20130100273A (ko) * 2010-08-27 2013-09-10 와카모토 세이야꾸 가부시끼가이샤 점안용 수성 조성물
WO2012145460A2 (en) 2011-04-22 2012-10-26 Alcon Research, Ltd. Ophthalmic composition with a viscosity enhancement system having two different viscosity enhancing agents
US20120270955A1 (en) 2011-04-22 2012-10-25 Chowhan Masood A Ophthalmic composition with a viscosity enhancement system having two different viscosity enhancing agents
TWI544922B (zh) 2011-05-19 2016-08-11 愛爾康研究有限公司 高濃度歐羅派特錠（ｏｌｏｐａｔａｄｉｎｅ）眼用組成物
CA2899342C (en) 2013-02-01 2021-09-21 Ocularis Pharma, Llc Methods and compositions for daily ophthalmic administration of phentolamine to improve visual performance
WO2014121027A1 (en) 2013-02-01 2014-08-07 Oculars Pharma, Llc Aqueous ophthalmic solutions of phentolamine and medical uses thereof
CN104208016A (zh) * 2013-05-29 2014-12-17 天津金耀集团有限公司 含有曲伏前列腺素的眼部制剂
CN103601206A (zh) * 2013-11-04 2014-02-26 天津大学 山梨醇络合-聚合制备二硼化锆纳米粉体的方法
US10632202B2 (en) 2016-03-04 2020-04-28 Johnson & Johnson Consumer Inc. Preservative containing compositions
CN106237337B (zh) * 2016-08-05 2019-11-08 河南中帅医药科技股份有限公司 一种液体药物制剂用防腐组合物
KR101770324B1 (ko) * 2016-11-09 2017-08-22 주식회사태준제약 안압 강하용 점안 조성물
GR1009419B (el) * 2017-11-07 2018-12-14 Φαρματεν Αβεε Οφθαλμικο φαρμακευτικο σκευασμα που περιεχει εναν συνδυασμο βρινζολαμιδης και βριμονιδινης και μεθοδος για την παρασκευη αυτου
CN113164451A (zh) 2018-10-15 2021-07-23 奥库菲尔制药股份有限公司 治疗青光眼的方法和组合物及相关病症
BR112021007725A2 (pt) 2018-10-26 2021-07-27 Ocuphire Pharma, Inc. métodos e composições para tratamento de presbiopia, midríase e outros distúrbios oculares
JP2020075918A (ja) * 2018-11-02 2020-05-21 千寿製薬株式会社 角膜上皮創傷治癒促進用の眼科用組成物
WO2022025831A1 (en) * 2020-07-26 2022-02-03 Verano Ilac Sanayi Ve Ticaret Anonim Sirketi Pharmaceutical compositions for injection comprising tulathromycin
CN115368310B (zh) 2021-05-18 2025-06-27 奥库菲尔医药公司 合成甲磺酸酚妥拉明的方法

Family Cites Families (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1289443A (es) 1970-01-30 1972-09-20
US3711708A (en) 1971-02-25 1973-01-16 Optical Coating Laboratory Inc Rapid scan identifier for use in infrared absorption spectroscopy
US3713709A (en) 1971-11-18 1973-01-30 Gen Electric Resilient axle lining dust guard
US4027020A (en) * 1974-10-29 1977-05-31 Millmaster Onyx Corporation Randomly terminated capped polymers
US3931319A (en) 1974-10-29 1976-01-06 Millmaster Onyx Corporation Capped polymers
DE2724675A1 (de) 1977-06-01 1978-12-14 Bayer Ag Tetrahydrofuran-derivate, verfahren zu ihrer herstellung sowie ihre verwendung als herbizide
GB2084870B (en) * 1980-10-10 1985-05-09 Muhlemann R Hans Oral compositions containing pyrimidine amine compounds and zinc salts
US4407791A (en) 1981-09-28 1983-10-04 Alcon Laboratories, Inc. Ophthalmic solutions
US4525346A (en) * 1981-09-28 1985-06-25 Alcon Laboratories, Inc. Aqueous antimicrobial ophthalmic solutions
US4836986A (en) 1984-09-28 1989-06-06 Bausch & Lomb Incorporated Disinfecting and preserving systems and methods of use
US5607698A (en) * 1988-08-04 1997-03-04 Ciba-Geigy Corporation Method of preserving ophthalmic solution and compositions therefor
US5037647A (en) * 1988-09-15 1991-08-06 Alcon Laboratories, Inc. Aqueous antimicrobial opthalmic solutions comprised of quaternary ammonium compound, citric acid, citrate and sodium chloride
CA2003198C (en) * 1988-11-29 1995-03-21 Anthony J. Dziabo, Jr. Aqueous ophthalmic solutions and method for preserving same
US5130298A (en) * 1989-05-16 1992-07-14 Ethicon, Inc. Stabilized compositions containing epidermal growth factor
US5145643A (en) 1990-01-05 1992-09-08 Allergan, Inc. Nonoxidative ophthalmic compositions and methods for preserving and using same
US5221664A (en) * 1990-04-23 1993-06-22 Magainin Pharmaaceuticals Inc. Composition and treatment with biologically active peptides and toxic cations
JP3058656B2 (ja) * 1990-06-18 2000-07-04 トーメー産業株式会社 コンタクトレンズ用液剤組成物及びそれを用いたコンタクトレンズの洗浄若しくは保存方法
EP0564510A1 (en) * 1990-12-27 1993-10-13 Allergan, Inc Method and composition for disinfecting contact lenses
US5460834A (en) * 1991-12-13 1995-10-24 Alcon Laboratories, Inc. Combinations of polymers for use in physiological tear compositions
EP0639070B2 (en) * 1992-05-06 2010-09-08 Alcon Laboratories, Inc. Use of borate-polyol complexes in ophthalmic compositions
US5505953A (en) 1992-05-06 1996-04-09 Alcon Laboratories, Inc. Use of borate-polyol complexes in ophthalmic compositions
US5352708A (en) * 1992-09-21 1994-10-04 Allergan, Inc. Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents
US5300287A (en) * 1992-11-04 1994-04-05 Alcon Laboratories, Inc. Polymeric antimicrobials and their use in pharmaceutical compositions
US5320843A (en) * 1992-12-10 1994-06-14 Polymer Technology Corporation Method for improving antibacterial properties of ophthalmic solutions
US5736165A (en) * 1993-05-25 1998-04-07 Allergan In-the-eye use of chlorine dioxide-containing compositions
TW274516B (es) * 1993-11-12 1996-04-21 Ciba Geigy Ag
AU3070395A (en) * 1994-07-22 1996-02-22 Alcon Laboratories, Inc. Use of low molecular weight amino acids in ophthalmic compositions
US5603929A (en) 1994-11-16 1997-02-18 Alcon Laboratories, Inc. Preserved ophthalmic drug compositions containing polymeric quaternary ammonium compounds
US6024954A (en) * 1994-12-12 2000-02-15 Allergan Compositions and methods for disinfecting contact lenses and preserving contact lens care products
US5631287A (en) 1994-12-22 1997-05-20 Alcon Laboratories, Inc. Storage-stable prostaglandin compositions
US6011062A (en) * 1994-12-22 2000-01-04 Alcon Laboratories, Inc. Storage-stable prostaglandin compositions
CA2211361A1 (en) * 1995-03-20 1996-09-26 Unilever Plc Liquid cleansing formulations
US5683993A (en) * 1995-06-22 1997-11-04 Ciba Vision Corporation Compositions and methods for stabilizing polymers
HU225329B1 (en) * 1996-09-12 2006-09-28 Richter Gedeon Vegyeszet Use of zinc or cobalt hyaluronate associate for the manufacture of pharmaceutical compositions of antimicrobial activity
AU4428397A (en) * 1996-09-20 1998-04-14 Warner-Lambert Company Oral compositions containing a zinc compound
US5820822A (en) * 1996-10-25 1998-10-13 Kross; Robert D. Antimicrobial composition and method of use
JPH10163044A (ja) 1996-12-02 1998-06-19 Matsushita Electric Ind Co Ltd コンバータトランス
PT1190718E (pt) * 1996-12-13 2006-08-31 Alcon Lab Inc Composicoes oftalmicas contendo aminoalcoois
AR002194A1 (es) * 1997-03-17 1998-01-07 Sanchez Reynaldo Alemany Instrumento computarizado para el analisis del movimiento.
US5858346A (en) * 1997-05-09 1999-01-12 Allergan Compositions and methods for enhancing contact lens wearability
US6265444B1 (en) * 1997-05-23 2001-07-24 Insite Vision Incorporated Ophthalmic composition
ES2206965T3 (es) * 1997-07-29 2004-05-16 Alcon Laboratories, Inc. Composiciones oftalmicas que contienen polimeros de galactomanana y borato.
WO2004073708A1 (en) * 1998-12-17 2004-09-02 Dean Thomas R Brinzolamide and brimonidine for treating ocular conditions
US6034043A (en) * 1999-04-20 2000-03-07 Lever Brothers Company, Division Of Conopco, Inc. Mild antimicrobial liquid cleansing formulations comprising polyvalent cation or cations for improving an antimicrobial effectiveness
US6482799B1 (en) * 1999-05-25 2002-11-19 The Regents Of The University Of California Self-preserving multipurpose ophthalmic solutions incorporating a polypeptide antimicrobial
US6166012A (en) * 1999-07-30 2000-12-26 Allergan Sales, Inc. Antibiotic compositions and method for using same
WO2002043482A2 (en) * 2000-11-29 2002-06-06 Novartis Ag Aqueous disinfecting systems
AR035509A1 (es) * 2000-12-21 2004-06-02 Alcon Inc Solucion de lagrimas artificiales mejorada que contiene una combinacion de tres emolientes y el uso de dicha solucion para la fabricacion de un medicamento
US6743439B1 (en) * 2001-06-27 2004-06-01 Alcon, Inc. Ophthalmic compositions containing copolymers of sulfonated styrene and maleic anhydride
US7074827B2 (en) * 2002-10-24 2006-07-11 Sucampo Ag (Usa) Inc. Method for treating ocular hypertension and glaucoma
TWI322828B (en) 2002-12-23 2010-04-01 Alcon Inc Use of multifunctional surface active agents to clean contact lenses
KR101059711B1 (ko) * 2003-01-21 2011-08-29 센주 세이야꾸 가부시키가이샤 2-아미노-3-(4-브로모벤조일)페닐아세트산 함유 수성액제
CA2545962A1 (en) * 2003-12-09 2005-07-07 Alcon, Inc. Use of organic buffering agents to enhance the antimicrobial activity of pharmaceutical compositions
EP2062872B1 (en) * 2003-12-09 2015-12-09 Novartis AG Use of bis-amines to enhance the antimicrobial activity of aqueous compositions
AU2004305539B2 (en) * 2003-12-11 2010-09-02 Alcon, Inc. Ophthalmic compositions containing a polysaccharide/borate gelling system
US20050214382A1 (en) * 2004-03-29 2005-09-29 Erning Xia Zinc preservative composition and method of use
US20060229219A1 (en) 2005-04-11 2006-10-12 Advanced Medical Optics, Inc. Borate-polyol mixtures as a buffering system
US20070212420A1 (en) * 2006-03-10 2007-09-13 Bausch & Lomb Incorporated Pharmaceutical formulations comprising polyanionic materials and zinc-based preservatives
US20070297990A1 (en) * 2006-06-27 2007-12-27 Shah Mandar V Self-preserving composition
TWI394564B (zh) † 2006-09-21 2013-05-01 Alcon Res Ltd 自行保存型水性藥學組成物
US20080095863A1 (en) * 2006-10-24 2008-04-24 Alcon Manufacturing Ltd. 2-pyrrolidone derivatives for preservation of ophthalmic, otic and nasal compositions
WO2008052037A2 (en) * 2006-10-24 2008-05-02 Alcon Research, Ltd. Packaging materials for formulations containing 2-pyrrolidone derivatives
DK2420223T3 (da) † 2008-03-17 2017-11-06 Novartis Ag Vandige farmaceutiske sammensætninger med borat-polyol-komplekser
TWI544927B (zh) 2008-03-17 2016-08-11 愛爾康研究有限公司 具有低濃度的表面活性劑以促進治療劑之生物可利用性的藥學組成物
TWI489997B (zh) * 2009-06-19 2015-07-01 Alcon Res Ltd 含有硼酸－多元醇錯合物之水性藥學組成物

Also Published As

Publication number Publication date
DE202009019116U1 (de) 2016-08-01
BRPI0909738A2 (pt) 2015-10-06
CN101959500A (zh) 2011-01-26
ES2644550T3 (es) 2017-11-29
EP2308466A1 (en) 2011-04-13
DK2308466T3 (en) 2017-09-11
EP2254549A2 (en) 2010-12-01
PL2254549T3 (pl) 2014-03-31
AU2009225931B2 (en) 2014-03-13
EP2420223A1 (en) 2012-02-22
DK2420223T3 (da) 2017-11-06
PL2254549T5 (pl) 2019-12-31
EP2254549B1 (en) 2013-11-06
CY1114712T1 (el) 2016-10-05
KR101541303B1 (ko) 2015-08-03
EP2420223B1 (en) 2017-07-19
AU2009225931A9 (en) 2014-04-17
DK2254549T3 (da) 2013-12-02
CA2717679C (en) 2013-07-23
TWI498122B (zh) 2015-09-01
US20140294750A1 (en) 2014-10-02
TW200942262A (en) 2009-10-16
SI2254549T1 (sl) 2014-01-31
HK1145631A1 (en) 2011-04-29
MX2010009336A (es) 2010-09-24
AU2009225931A1 (en) 2009-09-24
CA2717679A1 (en) 2009-09-24
CN105126109A (zh) 2015-12-09
KR20100127269A (ko) 2010-12-03
AU2009225931B9 (en) 2014-04-03
PT2254549E (pt) 2014-01-30
RU2010142353A (ru) 2012-04-27
SI2254549T2 (sl) 2019-08-30
RU2477631C2 (ru) 2013-03-20
CL2009000625A1 (es) 2010-01-04
DK2254549T4 (da) 2019-07-22
JP5583111B2 (ja) 2014-09-03
JP2011514382A (ja) 2011-05-06
EP2254549B2 (en) 2019-05-29
ES2638771T3 (es) 2017-10-24
WO2009117242A2 (en) 2009-09-24
AR070887A1 (es) 2010-05-12
EP2308466B1 (en) 2017-05-31
US20090232763A1 (en) 2009-09-17
HRP20131173T1 (hr) 2014-01-17
ES2443548T5 (es) 2020-01-23
WO2009117242A3 (en) 2010-02-04
ES2443548T3 (es) 2014-02-19
HRP20131173T4 (hr) 2019-07-12
ZA201005994B (en) 2011-10-26

Similar Documents

Publication Publication Date Title
UY31718A1 (es) Composiciones farmacéuticas acuosas que contienen complejos de borato y poliol
UY32709A (es) Composiciones farmacéuticas acuosas que contienen complejos borato-poliol
UY30605A1 (es) Composiciones farmacéuticas acuosas autoconservadas
BRPI0916286B8 (pt) amidofenóxi-indazóis úteis como inibidores de c-met, seus usos, e composição farmacêutica
AR047928A1 (es) Derivados de tetrahidropiridoindol
CR20110609A (es) Composicion antimicrobiana y metodos relacionados de uso
UY34359A (es) ?tratamiento de esclerosis múltiple con combinación de laquinimod e interferón-beta?.
CR11418A (es) Trans-clomifeno para el sindrome metabolico
ECSP088252A (es) 7-aza-indazoles sustituidos, composiciones que los contienen, procedimiento de fabricación y utilización
JO2721B1 (en) Derivatives of artemisia plant and its preparations and therapeutic applications
EA201591830A1 (ru) Фармацевтические композиции, включающие эверолимус
CR9114A (es) 2-alcoxi-3,4,5-trihydroxi-alquimidas, su preparacion composicones que las contienen y su utilizacion
CO6382078A2 (es) Agente rodenticida sinergico
CR20110660A (es) Mezclas fungicidas
BR112012013319A8 (pt) derivados espiro azacíclicos
UY29361A1 (es) Pirroles e imidazoles sustituídos, composiciones que los contienen, procedimiento de fabricación y utilización
MA32461B1 (fr) Dronedarone pour la prevention de cardioversion
CR9231A (es) Pirroles sustituidos, composiciones que los contienen, procesos de fabricacion y utilizacion
UY30586A1 (es) Derivados de tartrato como inhibidores del factor de coagulacion ixa
DOP2006000015A (es) Pirazolo piridinas sustituidas, composiciones que las contienen, procedimiento de fabricación
DOP2013000213A (es) Compuestos de complejos de fe(iii) para el tratamiento y profilaxis de sintomas de deficiencia de hierro y anemias por deficiencia de hierro
AR081024A1 (es) Asociacion de los inhibidores de la xantina oxidasa y la metformina y su uso
ECSP088893A (es) 2-alcoxi-3, 4,5-trihidroxi-alquilamida-benzazepinas, su preparación, composiciones que las contienen y utilización
ECSP088899A (es) Derivados de 2-alcoxi-3,4,5-trihidroxi-alquilamida, su preparación, composiciones que las contienen y utilización
CL2008001536A1 (es) Composicion farmaceutica compuesta por la combinacion sinergica de un agente antimicrobiano como ciprofloxacino y un agente antioxidante como acido ascorbico, la concentracion de ciprofloxacino va desde 250 mg hasta 1 gr y desde 50 mg hasta 200 mg para acido ascorbico, en una unidad de dosis; y uso en infecciones urinarias.

Legal Events

Date Code Title Description
RDES Application refused

Effective date: 20200724