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UY27236A1 - Inhibidores de pcp basados en ácidos 3-heterociclilpropanohidroxámicos - Google Patents

Inhibidores de pcp basados en ácidos 3-heterociclilpropanohidroxámicos

Info

Publication number
UY27236A1
UY27236A1 UY27236A UY27236A UY27236A1 UY 27236 A1 UY27236 A1 UY 27236A1 UY 27236 A UY27236 A UY 27236A UY 27236 A UY27236 A UY 27236A UY 27236 A1 UY27236 A1 UY 27236A1
Authority
UY
Uruguay
Prior art keywords
heterociclilpropanohydroxamic
acids
inhibitors based
pcp inhibitors
pcp
Prior art date
Application number
UY27236A
Other languages
English (en)
Inventor
Simon Bailey
Kim James
Paul V Fish
Gavin A Whitlock
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of UY27236A1 publication Critical patent/UY27236A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Compuestos de fórmula (I) y sus sales, solvatos y profármacos, en donde los sustituyentes son tales como han sido definidos en la presente memoria, son inhibidores de PCP.
UY27236A 2001-03-30 2002-03-27 Inhibidores de pcp basados en ácidos 3-heterociclilpropanohidroxámicos UY27236A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0108102.5A GB0108102D0 (en) 2001-03-30 2001-03-30 Compounds

Publications (1)

Publication Number Publication Date
UY27236A1 true UY27236A1 (es) 2002-11-29

Family

ID=9911984

Family Applications (1)

Application Number Title Priority Date Filing Date
UY27236A UY27236A1 (es) 2001-03-30 2002-03-27 Inhibidores de pcp basados en ácidos 3-heterociclilpropanohidroxámicos

Country Status (16)

Country Link
EP (1) EP1373264B1 (es)
JP (1) JP2004524365A (es)
AP (1) AP2002002466A0 (es)
AT (1) ATE285409T1 (es)
BR (1) BR0208499A (es)
CA (1) CA2442481A1 (es)
DE (1) DE60202358T2 (es)
ES (1) ES2232740T3 (es)
GB (1) GB0108102D0 (es)
GT (1) GT200200062A (es)
MX (1) MXPA03008944A (es)
PA (1) PA8542201A1 (es)
PE (1) PE20021045A1 (es)
TN (1) TNSN02036A1 (es)
UY (1) UY27236A1 (es)
WO (1) WO2002079200A1 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2926542T3 (es) 2003-04-11 2022-10-26 Ptc Therapeutics Inc Compuestos de ácido 1,2,4-oxadiazol benzoico y su uso para supresión de mutaciones finalizadoras y el tratamiento de enfermedades
WO2005058876A1 (en) * 2003-12-16 2005-06-30 Gpc Biotech Ag Pyrazine derivatives as effective compounds against infectious diseases
US7319108B2 (en) 2004-01-25 2008-01-15 Sanofi-Aventis Deutschland Gmbh Aryl-substituted heterocycles, process for their preparation and their use as medicaments
DE102004003812A1 (de) * 2004-01-25 2005-08-11 Aventis Pharma Deutschland Gmbh Arylsubstituierte Heterozyklen, Verfahren ihrer Herstellung und ihre Verwendung als Arzneimittel
CA2561831A1 (en) 2004-04-13 2005-12-22 Icagen, Inc. Polycyclic pyrazines as potassium ion channel modulators
RS54876B1 (sr) 2005-05-10 2016-10-31 Incyte Holdings Corp Modulatori indoleamina 2,3-dioksigenaze i metode za upotrebu istih
ES2540561T3 (es) 2005-12-20 2015-07-10 Incyte Corporation N-hidroxiamidinoheterociclos como moduladores de indolamina 2,3-dioxigenasa
JP5319532B2 (ja) 2006-09-19 2013-10-16 インサイト・コーポレイション インドールアミン２，３−ジオキシゲナーゼのモジュレーターとしてのｎ−ヒドロキシアミジノヘテロサイクル
CL2007002650A1 (es) 2006-09-19 2008-02-08 Incyte Corp Compuestos derivados de heterociclo n-hidroxiamino; composicion farmaceutica, util para tratar cancer, infecciones virales y desordenes neurodegenerativos entre otras.
DE102007025718A1 (de) 2007-06-01 2008-12-04 Merck Patent Gmbh Pyridazinonderivate
SMT201800206T1 (it) 2008-07-08 2018-05-02 Incyte Holdings Corp 1,2,5-ossadiazoli come inibitori di indoleamina 2,3-diossigenasi
ES2517265T3 (es) 2009-03-03 2014-11-03 Merck Serono S.A. Derivados de oxadiazol piridina
KR102370067B1 (ko) 2013-11-08 2022-03-04 인사이트 홀딩스 코포레이션 인돌아민 2,3-디옥시게나제 억제제의 합성 방법
KR20160106684A (ko) 2014-01-10 2016-09-12 글락소스미스클라인 인털렉츄얼 프로퍼티 (넘버 2) 리미티드 히드록시포름아미드 유도체 및 그의 용도
EP3113619A4 (en) 2014-03-06 2017-09-13 PTC Therapeutics, Inc. Pharmaceutical compositions and salts of a 1,2,4-oxadiazole benzoic acid
BR112018008838A8 (pt) 2015-10-30 2019-02-26 Ptc Therapeutics Inc método para tratar, prevenir, melhorar ou administrar uma doença epiléptica

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9725782D0 (en) * 1997-12-05 1998-02-04 Pfizer Ltd Therapeutic agents
WO2000058278A1 (fr) * 1999-03-26 2000-10-05 Shionogi & Co., Ltd. Derives d'acides amines $g(b)
GB9930570D0 (en) * 1999-12-23 2000-02-16 Pfizer Ltd Therapy

Also Published As

Publication number Publication date
WO2002079200A1 (en) 2002-10-10
DE60202358T2 (de) 2005-12-08
ATE285409T1 (de) 2005-01-15
EP1373264B1 (en) 2004-12-22
DE60202358D1 (en) 2005-01-27
GB0108102D0 (en) 2001-05-23
MXPA03008944A (es) 2003-12-08
ES2232740T3 (es) 2005-06-01
EP1373264A1 (en) 2004-01-02
TNSN02036A1 (fr) 2005-12-23
CA2442481A1 (en) 2002-10-10
AP2002002466A0 (en) 2002-06-30
GT200200062A (es) 2003-11-15
PE20021045A1 (es) 2002-11-19
JP2004524365A (ja) 2004-08-12
PA8542201A1 (es) 2002-10-28
BR0208499A (pt) 2004-04-20

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20141113