UA99294C2 - Способ получения пиразолов - Google Patents
Способ получения пиразоловInfo
- Publication number
- UA99294C2 UA99294C2 UAA200913319A UAA200913319A UA99294C2 UA 99294 C2 UA99294 C2 UA 99294C2 UA A200913319 A UAA200913319 A UA A200913319A UA A200913319 A UAA200913319 A UA A200913319A UA 99294 C2 UA99294 C2 UA 99294C2
- Authority
- UA
- Ukraine
- Prior art keywords
- compound
- formula
- production
- pyrazoles
- acid
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 150000003217 pyrazoles Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 8
- 239000002253 acid Substances 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
- HDZGCSFEDULWCS-UHFFFAOYSA-N monomethylhydrazine Chemical compound CNN HDZGCSFEDULWCS-UHFFFAOYSA-N 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 238000007127 saponification reaction Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
В заявке описан способ получения соединения формулы I (I), который включает a) реакцию соединения формулы II (II), где R1 и R2 независимо обозначают С1-С6 алкил, с метилгидразином в присутствии воды и органического растворителя, который не смешивается с водой, который инертный в реакциях омыления, с получением соединения формулы III (III), где R1 является таким, как определено для формулы I; и b) омыление указанного соединения in situ, что приводит к образованию соединения формулы I путем b1) добавления основания с образованием аниона соединения формулы I и дальнейшего добавления кислоты с образованием соединения формулы I; или b2) добавления кислоты с образованием соединения формулы I.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07010770A EP1997808A1 (en) | 2007-05-31 | 2007-05-31 | Process for the production of pyrazoles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA99294C2 true UA99294C2 (ru) | 2012-08-10 |
Family
ID=38561704
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200913319A UA99294C2 (ru) | 2007-05-31 | 2008-05-13 | Способ получения пиразолов |
Country Status (2)
| Country | Link |
|---|---|
| EP (1) | EP1997808A1 (ru) |
| UA (1) | UA99294C2 (ru) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101959840B (zh) * | 2008-02-29 | 2014-04-16 | 巴斯夫欧洲公司 | 制备2-烷氧基亚甲基-4,4-二氟-3-氧丁酸烷基酯的方法 |
| EP3797099B1 (en) | 2018-05-21 | 2023-11-01 | PI Industries Ltd. | Method for preparing substituted heterocyclic compounds |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002128763A (ja) * | 2000-10-27 | 2002-05-09 | Mitsui Chemicals Inc | １，３−ジアルキルピラゾール−４−カルボン酸の精製法 |
| US7585998B2 (en) * | 2003-07-01 | 2009-09-08 | Bayer Cropscience Ag | Method for producing difluoro-acetyl-acetic acid alkylesters |
| DE10349500A1 (de) * | 2003-10-23 | 2005-06-02 | Bayer Cropscience Ag | Verfahren zum Herstellen von 2-Dihalogenacyl-3-amino-acrylsäureestern und 3-Dihalogenmethyl-pyrazol-4-carbonsäureestern |
| EP1761498A1 (de) * | 2004-06-18 | 2007-03-14 | Basf Aktiengesellschaft | 1-methyl-3-difluormethyl-pyrazol-4-carbonsäure-(ortho-phenyl)-anilide und ihre verwendung als fungizid |
| CN101133031B (zh) * | 2005-02-25 | 2010-07-21 | 财团法人相模中央化学研究所 | 1-取代-3-氟代烷基吡唑-4-羧酸酯的制造方法 |
-
2007
- 2007-05-31 EP EP07010770A patent/EP1997808A1/en not_active Withdrawn
-
2008
- 2008-05-13 UA UAA200913319A patent/UA99294C2/ru unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1997808A1 (en) | 2008-12-03 |
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