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UA97816C2 - Compounds modulating c-kit and/or c-fms activity and use thereof - Google Patents

Compounds modulating c-kit and/or c-fms activity and use thereof

Info

Publication number
UA97816C2
UA97816C2 UAA200905046A UAA200905046A UA97816C2 UA 97816 C2 UA97816 C2 UA 97816C2 UA A200905046 A UAA200905046 A UA A200905046A UA A200905046 A UAA200905046 A UA A200905046A UA 97816 C2 UA97816 C2 UA 97816C2
Authority
UA
Ukraine
Prior art keywords
kit
fms
compounds modulating
fms activity
conditions
Prior art date
Application number
UAA200905046A
Other languages
English (en)
Ukrainian (uk)
Inventor
Чао Жанг
Джяжонг Жанг
Прабха Н. Ибрахим
Дин Р. Артис
Раян Бремер
Гуоксян Ву
Хонгяо Жу
Марика Неспи
Original Assignee
Плексикон, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39322825&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA97816(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Плексикон, Инк. filed Critical Плексикон, Инк.
Publication of UA97816C2 publication Critical patent/UA97816C2/ru

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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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Abstract

Получены соединения, которые имеют активность относительно рецептора тирозинкиназы c-kit и c-fms. Также описаны композиции, которые используются для лечения c-kit-опосредованного заболевания или состояния и c-fms-опосредованного заболевания или состояния, и их применение.
UAA200905046A 2006-11-22 2007-11-20 Compounds modulating c-kit and/or c-fms activity and use thereof UA97816C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86074906P 2006-11-22 2006-11-22
PCT/US2007/085289 WO2008064255A2 (en) 2006-11-22 2007-11-20 Compounds modulating c-fms and/or c-kit activity and uses therefor

Publications (1)

Publication Number Publication Date
UA97816C2 true UA97816C2 (en) 2012-03-26

Family

ID=39322825

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200905046A UA97816C2 (en) 2006-11-22 2007-11-20 Compounds modulating c-kit and/or c-fms activity and use thereof

Country Status (34)

Country Link
US (8) US7893075B2 (ru)
EP (1) EP2086972B1 (ru)
JP (4) JP2010510321A (ru)
KR (1) KR101506044B1 (ru)
CN (2) CN101605787B (ru)
AR (1) AR063878A1 (ru)
AU (1) AU2007323644B2 (ru)
BR (1) BRPI0721137B8 (ru)
CA (1) CA2670362C (ru)
CL (1) CL2007003326A1 (ru)
CO (1) CO6180438A2 (ru)
CR (1) CR10817A (ru)
DK (1) DK2086972T3 (ru)
EC (1) ECSP099357A (ru)
ES (1) ES2447779T3 (ru)
GT (1) GT200700101A (ru)
IL (1) IL198624A (ru)
MX (1) MX2009005428A (ru)
MY (1) MY158447A (ru)
NI (1) NI200900093A (ru)
NO (1) NO342175B1 (ru)
NZ (1) NZ577011A (ru)
PE (1) PE20081226A1 (ru)
PL (1) PL2086972T3 (ru)
PT (1) PT2086972E (ru)
RU (1) RU2452738C2 (ru)
SG (1) SG176511A1 (ru)
SI (1) SI2086972T1 (ru)
SV (1) SV2007002813A (ru)
TW (1) TWI432431B (ru)
UA (1) UA97816C2 (ru)
UY (1) UY30732A1 (ru)
WO (3) WO2008063888A2 (ru)
ZA (1) ZA200903458B (ru)

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SI1696920T1 (sl) 2003-12-19 2015-02-27 Plexxikon Inc. Spojine in postopki za razvoj modulatorjev ret
US7498342B2 (en) * 2004-06-17 2009-03-03 Plexxikon, Inc. Compounds modulating c-kit activity
MY153898A (en) * 2005-06-22 2015-04-15 Plexxikon Inc Compounds and methods for kinase modulation, and indications therefor
WO2008063888A2 (en) * 2006-11-22 2008-05-29 Plexxikon, Inc. Compounds modulating c-fms and/or c-kit activity and uses therefor
PE20121126A1 (es) * 2006-12-21 2012-08-24 Plexxikon Inc Compuestos pirrolo [2,3-b] piridinas como moduladores de quinasa
WO2008079909A1 (en) * 2006-12-21 2008-07-03 Plexxikon, Inc. Pyrrolo [2,3-b] pyridines as kinase modulators
MX2010000617A (es) 2007-07-17 2010-05-17 Plexxikon Inc Compuestos y metodos para modulacion de cinasa, e indicaciones de estos.
WO2009106441A1 (en) * 2008-02-25 2009-09-03 F. Hoffmann-La Roche Ag Pyrrolopyrazine kinase inhibitors
CA2713710A1 (en) 2008-02-25 2009-09-03 F. Hoffmann-La Roche Ag Pyrrolopyrazine kinase inhibitors
WO2009106445A1 (en) * 2008-02-25 2009-09-03 F. Hoffmann-La Roche Ag Pyrrolopyrazine kinase inhibitors
EP2247593B1 (en) 2008-02-25 2011-08-10 F. Hoffmann-La Roche AG Pyrrolopyrazine kinase inhibitors
CN101952294B (zh) 2008-02-25 2014-11-26 霍夫曼-拉罗奇有限公司 吡咯并吡嗪激酶抑制剂
WO2009143018A2 (en) * 2008-05-19 2009-11-26 Plexxikon, Inc. Compounds and methods for kinase modulation, and indications therefor
JP5767965B2 (ja) * 2008-06-10 2015-08-26 プレキシコン インコーポレーテッドＰｌｅｘｘｉｋｏｎ Ｉｎｃ． キナーゼを調節する５ｈ−ピロロ［２，３−ｂ］ピラジン誘導体、およびその適応症
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