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UA90864C2 - Halogenated benzamide derivatives - Google Patents

Halogenated benzamide derivatives

Info

Publication number
UA90864C2
UA90864C2 UAA200702713A UAA200702713A UA90864C2 UA 90864 C2 UA90864 C2 UA 90864C2 UA A200702713 A UAA200702713 A UA A200702713A UA A200702713 A UAA200702713 A UA A200702713A UA 90864 C2 UA90864 C2 UA 90864C2
Authority
UA
Ukraine
Prior art keywords
calkyl
ris
benzamide derivatives
halogenated benzamide
halogenated
Prior art date
Application number
UAA200702713A
Other languages
English (en)
Inventor
Жан Франсуа Россиньоль
Original Assignee
Ромарк Лебораториз, Л.К.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ромарк Лебораториз, Л.К. filed Critical Ромарк Лебораториз, Л.К.
Publication of UA90864C2 publication Critical patent/UA90864C2/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
UAA200702713A 2004-09-09 2005-06-09 Halogenated benzamide derivatives UA90864C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US60835404P 2004-09-09 2004-09-09

Publications (1)

Publication Number Publication Date
UA90864C2 true UA90864C2 (en) 2010-06-10

Family

ID=36060542

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200702713A UA90864C2 (en) 2004-09-09 2005-06-09 Halogenated benzamide derivatives

Country Status (25)

Country Link
US (3) US7285567B2 (ru)
EP (1) EP1789040B1 (ru)
JP (1) JP4998852B2 (ru)
KR (1) KR101344984B1 (ru)
CN (1) CN101035531B (ru)
AP (1) AP2451A (ru)
AU (1) AU2005285157B2 (ru)
BR (1) BRPI0515089B8 (ru)
CA (1) CA2580347C (ru)
CY (1) CY1118689T1 (ru)
DK (1) DK1789040T3 (ru)
EA (1) EA012606B1 (ru)
ES (1) ES2559672T3 (ru)
HR (1) HRP20151439T1 (ru)
HU (1) HUE026613T2 (ru)
IL (2) IL181849A (ru)
ME (1) ME02370B (ru)
MX (1) MX2007002969A (ru)
PL (1) PL1789040T3 (ru)
PT (1) PT1789040E (ru)
RS (1) RS54453B1 (ru)
SI (1) SI1789040T1 (ru)
UA (1) UA90864C2 (ru)
WO (1) WO2006031566A2 (ru)
ZA (1) ZA200702066B (ru)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL212910B1 (pl) * 2002-02-12 2012-12-31 Smithkline Beecham Corp Pochodna nikotynoamidu, srodek farmaceutyczny i zastosowanie pochodnej nikotynoamidu
UA90864C2 (en) * 2004-09-09 2010-06-10 Ромарк Лебораториз, Л.К. Halogenated benzamide derivatives
US20070015803A1 (en) * 2005-04-12 2007-01-18 Romark Laboratories L.C. Methods for treating diseases through interruption of protein maturation, compounds that inhibit the function of molecular chaperones such as protein disulfide isomerases or interfere with glycosylation, pharmaceutical compositions comprising them, and screening methods for identifying therapeutic agents
ES2422556T3 (es) 2006-01-09 2013-09-12 Romark Lab Lc Tratamiento de hepatitis vírica
ES2550755T3 (es) * 2007-08-03 2015-11-12 Romark Laboratories, L.C. Compuestos de tiazolida sustituidos con alquilsulfonilo
JP5726766B2 (ja) 2009-02-13 2015-06-03 ロマーク ラボラトリーズ エル．シー． ニタゾキサニドの制御放出医薬配合物
KR101760956B1 (ko) * 2009-05-12 2017-07-24 로마크 레버러토리즈, 엘.씨. 할로알킬 헤테로아릴 벤즈아미드 화합물
BRPI1014322A2 (pt) 2009-06-26 2015-08-25 Romark Lab Lc Método para tratar infecção, e para interromper ou evitar a produção de partículas virais infecciosas, combinação, e, composição farmacêutica.
CN102335171B (zh) * 2010-07-27 2013-09-11 中国农业科学院上海兽医研究所 一类n-(2-噻唑)苯甲酰胺衍生物的应用
JP6138764B2 (ja) 2011-05-16 2017-05-31 ロマーク ラボラトリーズ エル．シー． ウイルス性疾患、ガンおよび細胞内感染により引き起こされる疾患の予防および処置のためのチアゾリド化合物の使用
WO2014052831A1 (en) * 2012-09-28 2014-04-03 Xavier University Of Louisiana Anti-migration and anti-invasion thiazole analogs for treatment of cellular proliferative disease
JP6633092B2 (ja) 2014-11-11 2020-01-22 ロマーク ラボラトリーズ，リミティド カンパニー チゾキサニド、その類似体又は塩のプロドラッグを用いる組成物及び治療方法
CN108289961A (zh) 2016-03-31 2018-07-17 罗马克实验室有限公司 用于治疗病毒性感染的噻唑化物化合物
DK3442580T3 (da) 2016-04-11 2020-12-21 Genfit Fremgangsmåder til behandling af kolestatiske og fibrotiske sygdomme
WO2018195035A1 (en) 2017-04-18 2018-10-25 Romark Laboratories L.C. Inhibition of protein disulfide-isomerase a3
JP2023537237A (ja) 2020-07-20 2023-08-31 ロマーク ラボラトリーズ，リミティド カンパニー チゾキサニドおよび２－ヒドロキシ－ｎ－（５－クロロ－１，３－チアゾル－２－イル）ベンズアミド（ｒｍ－４８４８）とエタノールアミン、モルホリン、プロパノールアミン、ピペラジン、およびｎ－メチルピペラジンの結晶塩
CN116367892A (zh) 2020-08-24 2023-06-30 罗马克实验室有限公司 噻唑化物抗冠状病毒的用途
CN115197164B (zh) * 2021-04-12 2025-04-01 杜心赟 新型噻唑类化合物及其制备方法和用途

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1276663A (en) 1968-12-24 1972-06-07 Ici Ltd Stimulation of plant growth
PH9683A (en) * 1970-04-15 1976-02-10 P Haken Carboxamide derivatives and the use as fungicides thereof
GB1437800A (en) 1973-08-08 1976-06-03 Phavic Sprl Derivatives of 2-benzamido-5-nitro-thiazoles
US4315018A (en) 1978-12-07 1982-02-09 Rossignol Jean F Specific parasiticidal use of 2-benzamido-5-nitro-thiazole derivatives
JPS60205454A (ja) * 1984-03-29 1985-10-17 Mitsubishi Paper Mills Ltd 電子写真感光体
US5169846A (en) 1989-10-12 1992-12-08 Crooks Michael J Non-aqueous micellar solutions of anthelmintic benzimidazoles, closantel, or phenothiazine, and insect growth regulators
US5578612A (en) * 1990-10-15 1996-11-26 Pfizer Inc. Indole derivatives
US5387598A (en) * 1994-04-13 1995-02-07 Rossignol; Jean-Francois Composition and galenic formulation suitable for combatting affections of the lower abdomen
US5578621A (en) 1994-09-08 1996-11-26 Romark Lab Lc Benzamide derivatives
HUT77404A (hu) * 1994-04-13 1998-04-28 Jean-Francois Rossignol N-(5-nitro-2-tiazolil)-benzamid-származékok és az ezeket tartalmazó gyógyszerkészítmények
US5965590A (en) * 1994-09-08 1999-10-12 Romark Lab Lc Method for treatment of opportunistic infections with pharmaceutical compositions of tizoxanide and nitazoxanide
MX9604483A (es) * 1994-09-08 1998-02-28 Jean-Francois Rossignol Derivados de benzamida, composiciones que contienen dicho derivado y uso de las mismas.
US5856348A (en) * 1994-09-08 1999-01-05 Romark Laboratories, L.C. Method for treatment of trematodes with pharmaceutical compositions of tizoxanide and nitazoxanide
US5859038A (en) 1994-09-08 1999-01-12 Romark Laboratories, L.C. Method for treatment of helicobacter pylori infections
US5968961A (en) * 1997-05-07 1999-10-19 Romark Laboratories, L.C. Pharmaceutical compositions of tizoxanide and nitazoxanide
DE19528046A1 (de) * 1994-11-21 1996-05-23 Bayer Ag Triazolyl-Derivate
US5935591A (en) * 1998-01-15 1999-08-10 Romark Laboratories, L.C. Method for treatment of equine protozoal myeloencephalitis with thiazolides
GB9823871D0 (en) * 1998-10-30 1998-12-23 Pharmacia & Upjohn Spa 2-Amino-thiazole derivatives, process for their preparation, and their use as antitumour agents
EP1277729A4 (en) * 2000-04-28 2005-05-11 Sankyo Co MODULATORS OF PPAR (GAMMA)
JP2004504201A (ja) * 2000-07-14 2004-02-12 ブリード　オートモティブ　テクノロジィ、インコーポレイテッド エネルギー吸収型シートベルト巻取装置
KR20090090406A (ko) * 2000-12-18 2009-08-25 가부시키가이샤 이야쿠 분지 셋케이 겐쿠쇼 염증성 사이토카인 생산 유리 억제제
JP2003064056A (ja) * 2001-08-27 2003-03-05 Sankyo Co Ltd アミド誘導体
WO2003035602A1 (en) * 2001-10-25 2003-05-01 Sankyo Company, Limited Lipid modulators
EA009701B1 (ru) * 2002-06-06 2008-02-28 Инститьют Оф Медисинал Молекьюлар Дизайн. Инк. Противоаллергические средства
US6737382B1 (en) * 2002-10-23 2004-05-18 Nippon Soda Co. Ltd. Insecticidal aminothiazole derivatives
EP1713484A2 (en) * 2004-01-23 2006-10-25 Amgen Inc. Compounds and methods of use
UA90864C2 (en) * 2004-09-09 2010-06-10 Ромарк Лебораториз, Л.К. Halogenated benzamide derivatives

Also Published As

Publication number Publication date
MX2007002969A (es) 2008-02-15
ME02370B (me) 2016-06-20
EP1789040A4 (en) 2009-09-02
HK1106139A1 (zh) 2008-03-07
WO2006031566A2 (en) 2006-03-23
IL203061A (en) 2013-04-30
AP2451A (en) 2012-08-31
EA200700432A1 (ru) 2007-10-26
HRP20151439T1 (hr) 2016-02-12
DK1789040T3 (en) 2016-02-01
AU2005285157A1 (en) 2006-03-23
ES2559672T3 (es) 2016-02-15
ZA200702066B (en) 2008-08-27
BRPI0515089B1 (pt) 2019-07-16
US7645783B2 (en) 2010-01-12
RS54453B1 (sr) 2016-06-30
JP4998852B2 (ja) 2012-08-15
EP1789040B1 (en) 2015-12-23
KR101344984B1 (ko) 2013-12-24
BRPI0515089A (pt) 2008-07-08
KR20070052330A (ko) 2007-05-21
HUE026613T2 (hu) 2016-06-28
AU2005285157B2 (en) 2009-07-16
US20080097106A1 (en) 2008-04-24
CY1118689T1 (el) 2017-07-12
JP2008512474A (ja) 2008-04-24
CN101035531B (zh) 2013-01-02
AP2007003950A0 (en) 2007-04-30
US7285567B2 (en) 2007-10-23
US20060089396A1 (en) 2006-04-27
CN101035531A (zh) 2007-09-12
EP1789040A2 (en) 2007-05-30
CA2580347A1 (en) 2006-03-23
BRPI0515089B8 (pt) 2021-05-25
IL181849A (en) 2013-11-28
PL1789040T3 (pl) 2016-04-29
US7550493B2 (en) 2009-06-23
IL181849A0 (en) 2007-07-04
PT1789040E (pt) 2016-02-19
WO2006031566A3 (en) 2006-06-08
SI1789040T1 (sl) 2016-02-29
US20080096941A1 (en) 2008-04-24
EA012606B1 (ru) 2009-10-30
CA2580347C (en) 2013-12-10

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