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UA89781C2 - Рідкий склад гормона росту - Google Patents

Рідкий склад гормона росту

Info

Publication number
UA89781C2
UA89781C2 UAA200611724A UAA200611724A UA89781C2 UA 89781 C2 UA89781 C2 UA 89781C2 UA A200611724 A UAA200611724 A UA A200611724A UA A200611724 A UAA200611724 A UA A200611724A UA 89781 C2 UA89781 C2 UA 89781C2
Authority
UA
Ukraine
Prior art keywords
growth hormone
liquid growth
hormone formulation
metal salt
alkaline earth
Prior art date
Application number
UAA200611724A
Other languages
English (en)
Russian (ru)
Inventor
Тьюдор Арвінт
Клебер Карін Люе
Original Assignee
Арес Трейдінг С.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Арес Трейдінг С.А. filed Critical Арес Трейдінг С.А.
Publication of UA89781C2 publication Critical patent/UA89781C2/uk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Inorganic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Даний винахід належить до рідкого складу, що містить гормон росту; цитрат/буфер фосфату, сіль лужного металу і сіль лужноземельного металу або сіль псевдолужноземельного металу, поліпропілен-поліетилен гліколь.
UAA200611724A 2004-04-07 2005-03-30 Рідкий склад гормона росту UA89781C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04101444 2004-04-07
PCT/EP2005/051448 WO2005105148A2 (en) 2004-04-07 2005-03-30 Liquid growth hormone formulation

Publications (1)

Publication Number Publication Date
UA89781C2 true UA89781C2 (uk) 2010-03-10

Family

ID=34928942

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200611724A UA89781C2 (uk) 2004-04-07 2005-03-30 Рідкий склад гормона росту

Country Status (23)

Country Link
US (1) US7662393B2 (uk)
EP (1) EP1740213B9 (uk)
JP (1) JP4991522B2 (uk)
KR (1) KR101120879B1 (uk)
CN (1) CN100574801C (uk)
AT (1) ATE547121T1 (uk)
AU (1) AU2005237775B2 (uk)
BR (1) BRPI0508798A (uk)
CA (1) CA2559918A1 (uk)
CY (1) CY1113834T1 (uk)
DK (1) DK1740213T3 (uk)
EA (1) EA010626B1 (uk)
ES (1) ES2383994T3 (uk)
HR (1) HRP20120235T1 (uk)
IL (1) IL178416A (uk)
MX (1) MXPA06011029A (uk)
NO (1) NO337249B1 (uk)
PL (1) PL1740213T3 (uk)
PT (1) PT1740213E (uk)
RS (1) RS52310B (uk)
SI (1) SI1740213T1 (uk)
UA (1) UA89781C2 (uk)
WO (1) WO2005105148A2 (uk)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1202157C (zh) * 1999-12-03 2005-05-18 东丽株式会社 成型加工用双向拉伸聚酯薄膜
JP2010523501A (ja) * 2007-04-04 2010-07-15 セラテクノロジーズ インコーポレイティド Ｇｈｒｈ分子の医薬製剤
AU2011208620B2 (en) 2010-01-22 2015-04-16 Novo Nordisk Health Care Ag Stable growth hormone compounds
CN103002918B (zh) 2010-01-22 2016-05-04 诺沃—诺迪斯克保健股份有限公司 体内功效延长的生长激素
EP2417982A1 (en) * 2010-07-30 2012-02-15 Ferring B.V. Stabilization of gonadotropins
BR112014001921B1 (pt) 2011-07-25 2022-05-10 Sandoz Ag Formulação aquosa farmaceuticamente aceitável, método para aumentar a estabilidade de uma formulação aquosa farmaceuticamente aceitável e embalagem principal
US8871713B2 (en) * 2013-03-01 2014-10-28 Theratechnologies Inc. Formulations of growth hormone releasing factor (GRF) molecules with improved stability
EP2981282B1 (en) 2013-04-05 2020-11-04 Novo Nordisk Health Care AG Growth hormone compound formulation
JP2017165713A (ja) * 2016-03-14 2017-09-21 Ｊｃｒファーマ株式会社 血清アルブミン−２０ｋ成長ホルモン融合タンパク質
CA3071930A1 (en) 2017-08-08 2019-02-14 Csl Behring Ag Hemopexin formulations
EP3811962A4 (en) * 2018-06-25 2022-03-16 JCR Pharmaceuticals Co., Ltd. Protein-containing aqueous liquid formulation
US20250325560A1 (en) 2022-07-29 2025-10-23 University Of Rochester Methods for improving muscle mass, strength, or function with a combination of testosterone and growth hormone

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3325223A1 (de) * 1983-07-13 1985-01-24 Hoechst Ag, 6230 Frankfurt Gegen denaturierung bestaendige, waessrige proteinloesungen, verfahren zu ihrer herstellung und ihre verwendung
JPS60123426A (ja) * 1983-12-07 1985-07-02 Eisai Co Ltd 経鼻投与用セクレチン製剤
EP0179808B1 (en) * 1984-04-09 1991-10-30 The Du Pont Merck Pharmaceutical Company Pharmaceutical composition suitable for treatment or prophylaxis of cardiac disorders
JPS6270319A (ja) * 1985-07-30 1987-03-31 インタ−ナシヨナル・ミネラルズ・アンド・ケミカル・コ−ポレイシヨン 成長促進ホルモンの安定化
WO1994003198A1 (en) 1992-07-31 1994-02-17 Genentech, Inc. Human growth hormone aqueous formulation
US5681814A (en) * 1990-06-07 1997-10-28 Genentech, Inc. Formulated IGF-I Composition
HUT67319A (en) * 1991-08-30 1995-03-28 Life Medical Sciences Inc Compositions for treating wounds
SE9201073D0 (sv) * 1992-04-03 1992-04-03 Kabi Pharmacia Ab Protein formulation
JPH0892125A (ja) * 1994-09-21 1996-04-09 Nippon Chem Res Kk 水性医薬組成物
AUPN801296A0 (en) * 1996-02-12 1996-03-07 Csl Limited Stabilised growth hormone formulation and method of preparation thereof
US20020077461A1 (en) * 1996-04-24 2002-06-20 Soren Bjorn Pharmaceutical formulation
US6759393B1 (en) * 1999-04-12 2004-07-06 Pfizer Inc. Growth hormone and growth hormone releasing hormone compositions
KR20020031388A (ko) * 1999-07-12 2002-05-01 그란디스 비오테크 게엠베하 성장 호르몬 제제
MXPA03001092A (es) * 2000-08-07 2003-09-25 Nektar Therapeutics Al Corp Polvos de proteina de haz de 4 helices secados por rocio, inhalables, que tienen agregacion minimizada.
CA2466642C (en) * 2001-11-14 2011-01-18 Guohua Chen Injectable depot composition
MXPA05000412A (es) * 2002-07-09 2005-07-22 Sandoz Ag Formulacioneks liquidas con una alta concentracion de hormona de crecimiento humana (hgh) que comprenden glicina.
EP1603588A2 (en) * 2003-03-18 2005-12-14 Ares Trading S.A. Stabilisation of growth hormones in solution

Also Published As

Publication number Publication date
PT1740213E (pt) 2012-03-21
KR20070005628A (ko) 2007-01-10
WO2005105148A3 (en) 2006-07-20
EA010626B1 (ru) 2008-10-30
CN1946427A (zh) 2007-04-11
KR101120879B1 (ko) 2012-02-27
HRP20120235T1 (hr) 2012-04-30
US7662393B2 (en) 2010-02-16
RS52310B (sr) 2012-12-31
CY1113834T1 (el) 2016-07-27
ES2383994T3 (es) 2012-06-28
MXPA06011029A (es) 2007-01-25
BRPI0508798A (pt) 2007-09-04
JP2007532515A (ja) 2007-11-15
IL178416A (en) 2012-12-31
EP1740213B1 (en) 2012-02-29
SI1740213T1 (sl) 2012-04-30
CN100574801C (zh) 2009-12-30
NO337249B1 (no) 2016-02-22
IL178416A0 (en) 2007-02-11
HK1098708A1 (zh) 2007-07-27
PL1740213T3 (pl) 2012-08-31
EA200601874A1 (ru) 2007-02-27
AU2005237775B2 (en) 2010-03-04
AU2005237775A1 (en) 2005-11-10
WO2005105148A8 (en) 2005-12-08
US20080038292A1 (en) 2008-02-14
EP1740213A2 (en) 2007-01-10
NO20065097L (no) 2007-01-02
WO2005105148A2 (en) 2005-11-10
DK1740213T3 (da) 2012-04-10
JP4991522B2 (ja) 2012-08-01
ATE547121T1 (de) 2012-03-15
CA2559918A1 (en) 2005-11-10
EP1740213B9 (en) 2012-06-13

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