UA84714C2 - Normal;heading 1;heading 2;IMIDAZOPYRIDINE SUBSTITUTED TROPANE DERIVATIVES WITH CCR5 RECEPTOR ANTAGONIST ACTIVITY FOR THE TREATMENT OF HIV AND INFLAMMATION - Google Patents
Normal;heading 1;heading 2;IMIDAZOPYRIDINE SUBSTITUTED TROPANE DERIVATIVES WITH CCR5 RECEPTOR ANTAGONIST ACTIVITY FOR THE TREATMENT OF HIV AND INFLAMMATIONInfo
- Publication number
- UA84714C2 UA84714C2 UAA200603711A UAA200603711A UA84714C2 UA 84714 C2 UA84714 C2 UA 84714C2 UA A200603711 A UAA200603711 A UA A200603711A UA A200603711 A UAA200603711 A UA A200603711A UA 84714 C2 UA84714 C2 UA 84714C2
- Authority
- UA
- Ukraine
- Prior art keywords
- heading
- treatment
- hiv
- inflammation
- normal
- Prior art date
Links
- 230000000694 effects Effects 0.000 title abstract 2
- GAMYYCRTACQSBR-UHFFFAOYSA-N 4-azabenzimidazole Chemical group C1=CC=C2NC=NC2=N1 GAMYYCRTACQSBR-UHFFFAOYSA-N 0.000 title 1
- 206010061218 Inflammation Diseases 0.000 title 1
- 239000003067 chemokine receptor CCR5 antagonist Substances 0.000 title 1
- 230000004054 inflammatory process Effects 0.000 title 1
- 150000003813 tropane derivatives Chemical class 0.000 title 1
- 102000004274 CCR5 Receptors Human genes 0.000 abstract 2
- 108010017088 CCR5 Receptors Proteins 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 102000019034 Chemokines Human genes 0.000 abstract 1
- 108010012236 Chemokines Proteins 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 241001430294 unidentified retrovirus Species 0.000 abstract 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present invention provides compounds of formula (I) wherein Rand Rare as defined hereinabove. The compounds of the present invention are modulators, especially antagonists, of the activity of chemokine CCR5 receptors. Modulators of the CCR5 receptor may be useful in the treatment of various inflammatory diseases and conditions, and in the treatment of infection by HIV and genetically related retroviruses.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0323236.0A GB0323236D0 (en) | 2003-10-03 | 2003-10-03 | Chemical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA84714C2 true UA84714C2 (en) | 2008-11-25 |
Family
ID=29415495
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200603711A UA84714C2 (en) | 2003-10-03 | 2004-09-28 | Normal;heading 1;heading 2;IMIDAZOPYRIDINE SUBSTITUTED TROPANE DERIVATIVES WITH CCR5 RECEPTOR ANTAGONIST ACTIVITY FOR THE TREATMENT OF HIV AND INFLAMMATION |
Country Status (5)
| Country | Link |
|---|---|
| CN (2) | CN100526313C (en) |
| GB (1) | GB0323236D0 (en) |
| GT (1) | GT200400203A (en) |
| UA (1) | UA84714C2 (en) |
| ZA (1) | ZA200602096B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5476307B2 (en) * | 2007-10-25 | 2014-04-23 | エグゼリクシス， インコーポレイテッド | Tropane compound |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20001420A1 (en) * | 1998-12-23 | 2000-12-18 | Pfizer | CCR5 MODULATORS |
| EP1492789B1 (en) * | 2002-04-08 | 2006-06-07 | Pfizer Limited | Tropane derivatives as ccr5 modulators |
-
2003
- 2003-10-03 GB GBGB0323236.0A patent/GB0323236D0/en not_active Ceased
-
2004
- 2004-09-28 CN CNB2004800286836A patent/CN100526313C/en not_active Expired - Fee Related
- 2004-09-28 CN CN200910146182A patent/CN101632664A/en active Pending
- 2004-09-28 UA UAA200603711A patent/UA84714C2/en unknown
- 2004-10-01 GT GT200400203A patent/GT200400203A/en unknown
-
2006
- 2006-03-10 ZA ZA200602096A patent/ZA200602096B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB0323236D0 (en) | 2003-11-05 |
| GT200400203A (en) | 2005-04-18 |
| CN100526313C (en) | 2009-08-12 |
| CN1863801A (en) | 2006-11-15 |
| ZA200602096B (en) | 2007-05-30 |
| CN101632664A (en) | 2010-01-27 |
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