UA84714C2 - Производные имидазопиридинзамещенного тропана с антагонистической активностью ccr5 рецепторов для лечения вич и воспаления - Google Patents
Производные имидазопиридинзамещенного тропана с антагонистической активностью ccr5 рецепторов для лечения вич и воспаленияInfo
- Publication number
- UA84714C2 UA84714C2 UAA200603711A UAA200603711A UA84714C2 UA 84714 C2 UA84714 C2 UA 84714C2 UA A200603711 A UAA200603711 A UA A200603711A UA A200603711 A UAA200603711 A UA A200603711A UA 84714 C2 UA84714 C2 UA 84714C2
- Authority
- UA
- Ukraine
- Prior art keywords
- heading
- treatment
- hiv
- inflammation
- normal
- Prior art date
Links
- 230000000694 effects Effects 0.000 title abstract 2
- GAMYYCRTACQSBR-UHFFFAOYSA-N 4-azabenzimidazole Chemical group C1=CC=C2NC=NC2=N1 GAMYYCRTACQSBR-UHFFFAOYSA-N 0.000 title 1
- 206010061218 Inflammation Diseases 0.000 title 1
- 239000003067 chemokine receptor CCR5 antagonist Substances 0.000 title 1
- 230000004054 inflammatory process Effects 0.000 title 1
- 150000003813 tropane derivatives Chemical class 0.000 title 1
- 102000004274 CCR5 Receptors Human genes 0.000 abstract 2
- 108010017088 CCR5 Receptors Proteins 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 102000019034 Chemokines Human genes 0.000 abstract 1
- 108010012236 Chemokines Proteins 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 241001430294 unidentified retrovirus Species 0.000 abstract 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Представленное изобретение касается соединений формулы (І)где Rи Rимеют значение, определенные в описании изобретения.Соединения согласно изобретению являются модуляторами, особенно антагонистами активности хемокиновых CCR5 рецепторов. Модуляторы CCR5 рецептора могут использоваться при лечении разных воспалительных заболеваний и состояний, и при лечении инфекции ВИЧ и генетически связанных ретровирусных инфекций.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0323236.0A GB0323236D0 (en) | 2003-10-03 | 2003-10-03 | Chemical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA84714C2 true UA84714C2 (ru) | 2008-11-25 |
Family
ID=29415495
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200603711A UA84714C2 (ru) | 2003-10-03 | 2004-09-28 | Производные имидазопиридинзамещенного тропана с антагонистической активностью ccr5 рецепторов для лечения вич и воспаления |
Country Status (5)
| Country | Link |
|---|---|
| CN (2) | CN100526313C (ru) |
| GB (1) | GB0323236D0 (ru) |
| GT (1) | GT200400203A (ru) |
| UA (1) | UA84714C2 (ru) |
| ZA (1) | ZA200602096B (ru) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5476307B2 (ja) * | 2007-10-25 | 2014-04-23 | エグゼリクシス， インコーポレイテッド | トロパン化合物 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20001420A1 (es) * | 1998-12-23 | 2000-12-18 | Pfizer | Moduladores de ccr5 |
| EP1492789B1 (en) * | 2002-04-08 | 2006-06-07 | Pfizer Limited | Tropane derivatives as ccr5 modulators |
-
2003
- 2003-10-03 GB GBGB0323236.0A patent/GB0323236D0/en not_active Ceased
-
2004
- 2004-09-28 CN CNB2004800286836A patent/CN100526313C/zh not_active Expired - Fee Related
- 2004-09-28 CN CN200910146182A patent/CN101632664A/zh active Pending
- 2004-09-28 UA UAA200603711A patent/UA84714C2/ru unknown
- 2004-10-01 GT GT200400203A patent/GT200400203A/es unknown
-
2006
- 2006-03-10 ZA ZA200602096A patent/ZA200602096B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB0323236D0 (en) | 2003-11-05 |
| GT200400203A (es) | 2005-04-18 |
| CN100526313C (zh) | 2009-08-12 |
| CN1863801A (zh) | 2006-11-15 |
| ZA200602096B (en) | 2007-05-30 |
| CN101632664A (zh) | 2010-01-27 |
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