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UA48989C2 - Translated By PlajПРОИЗВОДНЫЕ 1-АРИЛСУЛЬФОНИЛ, АРИЛ(ТИО)КАРБОНИЛПИРИДАЗИНА, СПОСОБ ИХ ПОЛУЧЕНИЯ, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ И СПОСОБ ЛЕЧЕНИЯ - Google Patents

Translated By PlajПРОИЗВОДНЫЕ 1-АРИЛСУЛЬФОНИЛ, АРИЛ(ТИО)КАРБОНИЛПИРИДАЗИНА, СПОСОБ ИХ ПОЛУЧЕНИЯ, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ И СПОСОБ ЛЕЧЕНИЯ

Info

Publication number
UA48989C2
UA48989C2 UA98052267A UA98052267A UA48989C2 UA 48989 C2 UA48989 C2 UA 48989C2 UA 98052267 A UA98052267 A UA 98052267A UA 98052267 A UA98052267 A UA 98052267A UA 48989 C2 UA48989 C2 UA 48989C2
Authority
UA
Ukraine
Prior art keywords
derivatives
carbonylpyridazine
arylsulfonyl
thio
aryl
Prior art date
Application number
UA98052267A
Other languages
English (en)
Ukrainian (uk)
Inventor
Дональд У. Комбз
Original Assignee
Орто-Макнейл Фармасьютікел, Інк.
Орто-Макнейл Фармасьютикел, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Орто-Макнейл Фармасьютікел, Інк., Орто-Макнейл Фармасьютикел, Инк. filed Critical Орто-Макнейл Фармасьютікел, Інк.
Publication of UA48989C2 publication Critical patent/UA48989C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06—Antiabortive agents; Labour repressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/36—Benzo-cinnolines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Reproductive Health (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Gynecology & Obstetrics (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Pregnancy & Childbirth (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Описываются производные 1-арилсульфонил, арилкарбонил, арил(тио)карбонилпиридазина и методы получения упомянутых производных. Описываются новые нестероидные гетероциклические соединения, проявляющие активность прогестина и / или антипрогестина и имеющие высокую in vitro родственность к прегестиновому рецептору матки, груди или костей. Нестероидные гетероциклические производные также используют для контрацепции, менопаузы, остеопороза или эндометриоза.
UA98052267A 1995-11-06 1996-10-10 Translated By PlajПРОИЗВОДНЫЕ 1-АРИЛСУЛЬФОНИЛ, АРИЛ(ТИО)КАРБОНИЛПИРИДАЗИНА, СПОСОБ ИХ ПОЛУЧЕНИЯ, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ И СПОСОБ ЛЕЧЕНИЯ UA48989C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US790095P 1995-11-06 1995-11-06
PCT/US1996/016227 WO1997017332A1 (en) 1995-11-06 1996-10-10 1-arylsulphonyl, aryl(thio)carbonyl pyridazino derivatives and methods of preparation

Publications (1)

Publication Number Publication Date
UA48989C2 true UA48989C2 (ru) 2002-09-16

Family

ID=21728709

Family Applications (1)

Application Number Title Priority Date Filing Date
UA98052267A UA48989C2 (ru) 1995-11-06 1996-10-10 Translated By PlajПРОИЗВОДНЫЕ 1-АРИЛСУЛЬФОНИЛ, АРИЛ(ТИО)КАРБОНИЛПИРИДАЗИНА, СПОСОБ ИХ ПОЛУЧЕНИЯ, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ И СПОСОБ ЛЕЧЕНИЯ

Country Status (17)

Country Link
JP (1) JP2000501073A (ru)
KR (1) KR100360614B1 (ru)
CN (1) CN1110485C (ru)
AU (1) AU704507B2 (ru)
BR (1) BR9611407A (ru)
CZ (1) CZ286789B6 (ru)
HU (1) HU225162B1 (ru)
IL (1) IL124320A (ru)
MX (1) MX9803605A (ru)
NO (1) NO310460B1 (ru)
NZ (1) NZ319979A (ru)
PL (1) PL185618B1 (ru)
RU (1) RU2175969C2 (ru)
TW (1) TW460467B (ru)
UA (1) UA48989C2 (ru)
WO (1) WO1997017332A1 (ru)
ZA (1) ZA969298B (ru)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816467A (en) * 1987-01-09 1989-03-28 Farmitalia Carlo Erba S.R.L Heteroaryl 3-oxo-propanenitrile derivatives, pharmaceutical compositions and use
WO1989004306A1 (fr) * 1987-11-02 1989-05-18 Yoshitomi Pharmaceutical Industries, Ltd. Composes de pyridazine fusionnes et leurs utilisations medicales
WO1993004069A1 (fr) * 1991-08-27 1993-03-04 Yoshitomi Pharmaceutical Industries, Ltd. Compose de pyridazine lie par fusion et utilisation pharmaceutique d'un tel compose

Also Published As

Publication number Publication date
PL326669A1 (en) 1998-10-12
HUP0201305A3 (en) 2003-02-28
NO310460B1 (no) 2001-07-09
CZ286789B6 (en) 2000-07-12
BR9611407A (pt) 1999-12-28
CN1207091A (zh) 1999-02-03
IL124320A0 (en) 1998-12-06
TW460467B (en) 2001-10-21
ZA969298B (en) 1998-05-05
AU7263796A (en) 1997-05-29
CN1110485C (zh) 2003-06-04
HUP0201305A2 (hu) 2002-12-28
KR19990067340A (ko) 1999-08-16
CZ138098A3 (cs) 1998-09-16
IL124320A (en) 2001-10-31
RU2175969C2 (ru) 2001-11-20
NO982030D0 (no) 1998-05-05
KR100360614B1 (ko) 2003-06-02
PL185618B1 (pl) 2003-06-30
NO982030L (no) 1998-06-23
AU704507B2 (en) 1999-04-22
HU225162B1 (en) 2006-07-28
MX9803605A (es) 1998-09-30
JP2000501073A (ja) 2000-02-02
WO1997017332A1 (en) 1997-05-15
NZ319979A (en) 1999-11-29

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UA48989C2 (ru) Translated By PlajПРОИЗВОДНЫЕ 1-АРИЛСУЛЬФОНИЛ, АРИЛ(ТИО)КАРБОНИЛПИРИДАЗИНА, СПОСОБ ИХ ПОЛУЧЕНИЯ, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ И СПОСОБ ЛЕЧЕНИЯ
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