TWI868553B - Granular structure with active compound of organic acids and method for preparing the same - Google Patents
Granular structure with active compound of organic acids and method for preparing the same Download PDFInfo
- Publication number
- TWI868553B TWI868553B TW111150976A TW111150976A TWI868553B TW I868553 B TWI868553 B TW I868553B TW 111150976 A TW111150976 A TW 111150976A TW 111150976 A TW111150976 A TW 111150976A TW I868553 B TWI868553 B TW I868553B
- Authority
- TW
- Taiwan
- Prior art keywords
- particle structure
- acid
- core
- present disclosure
- flavoring
- Prior art date
Links
- 150000007524 organic acids Chemical class 0.000 title claims abstract description 30
- 238000000034 method Methods 0.000 title claims abstract description 22
- 235000005985 organic acids Nutrition 0.000 title abstract description 15
- 150000001875 compounds Chemical class 0.000 title description 2
- 239000004615 ingredient Substances 0.000 claims abstract description 35
- 239000000835 fiber Substances 0.000 claims abstract description 29
- 239000011241 protective layer Substances 0.000 claims abstract description 27
- 239000010410 layer Substances 0.000 claims abstract description 26
- 235000001674 Agaricus brunnescens Nutrition 0.000 claims abstract description 25
- 235000019226 kombucha tea Nutrition 0.000 claims abstract description 19
- 239000007921 spray Substances 0.000 claims abstract description 14
- 238000005469 granulation Methods 0.000 claims abstract description 13
- 230000003179 granulation Effects 0.000 claims abstract description 13
- 238000002156 mixing Methods 0.000 claims abstract description 11
- 238000000855 fermentation Methods 0.000 claims abstract description 6
- 230000004151 fermentation Effects 0.000 claims abstract description 6
- 239000002245 particle Substances 0.000 claims description 69
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 26
- 239000000843 powder Substances 0.000 claims description 26
- 239000007788 liquid Substances 0.000 claims description 24
- 244000269722 Thea sinensis Species 0.000 claims description 17
- 235000006468 Thea sinensis Nutrition 0.000 claims description 15
- 235000020279 black tea Nutrition 0.000 claims description 15
- 235000011194 food seasoning agent Nutrition 0.000 claims description 13
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 12
- 239000006041 probiotic Substances 0.000 claims description 11
- 235000018291 probiotics Nutrition 0.000 claims description 11
- 230000008569 process Effects 0.000 claims description 10
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 claims description 9
- RGHNJXZEOKUKBD-SQOUGZDYSA-N D-gluconic acid Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O RGHNJXZEOKUKBD-SQOUGZDYSA-N 0.000 claims description 8
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims description 8
- 239000003094 microcapsule Substances 0.000 claims description 8
- FTSSQIKWUOOEGC-RULYVFMPSA-N fructooligosaccharide Chemical compound OC[C@H]1O[C@@](CO)(OC[C@@]2(OC[C@@]3(OC[C@@]4(OC[C@@]5(OC[C@@]6(OC[C@@]7(OC[C@@]8(OC[C@@]9(OC[C@@]%10(OC[C@@]%11(O[C@H]%12O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%12O)O[C@H](CO)[C@@H](O)[C@@H]%11O)O[C@H](CO)[C@@H](O)[C@@H]%10O)O[C@H](CO)[C@@H](O)[C@@H]9O)O[C@H](CO)[C@@H](O)[C@@H]8O)O[C@H](CO)[C@@H](O)[C@@H]7O)O[C@H](CO)[C@@H](O)[C@@H]6O)O[C@H](CO)[C@@H](O)[C@@H]5O)O[C@H](CO)[C@@H](O)[C@@H]4O)O[C@H](CO)[C@@H](O)[C@@H]3O)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@@H](O)[C@@H]1O FTSSQIKWUOOEGC-RULYVFMPSA-N 0.000 claims description 7
- 229940107187 fructooligosaccharide Drugs 0.000 claims description 7
- 235000019225 fermented tea Nutrition 0.000 claims description 6
- KDYFGRWQOYBRFD-UHFFFAOYSA-N Succinic acid Natural products OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 claims description 5
- 230000000529 probiotic effect Effects 0.000 claims description 5
- RGHNJXZEOKUKBD-UHFFFAOYSA-N D-gluconic acid Natural products OCC(O)C(O)C(O)C(O)C(O)=O RGHNJXZEOKUKBD-UHFFFAOYSA-N 0.000 claims description 4
- KDYFGRWQOYBRFD-NUQCWPJISA-N butanedioic acid Chemical compound O[14C](=O)CC[14C](O)=O KDYFGRWQOYBRFD-NUQCWPJISA-N 0.000 claims description 4
- 238000001035 drying Methods 0.000 claims description 4
- 239000000174 gluconic acid Substances 0.000 claims description 4
- 235000012208 gluconic acid Nutrition 0.000 claims description 4
- 239000004310 lactic acid Substances 0.000 claims description 4
- 235000014655 lactic acid Nutrition 0.000 claims description 4
- 241000894006 Bacteria Species 0.000 claims description 3
- IAJILQKETJEXLJ-UHFFFAOYSA-N Galacturonsaeure Natural products O=CC(O)C(O)C(O)C(O)C(O)=O IAJILQKETJEXLJ-UHFFFAOYSA-N 0.000 claims description 3
- 229940097043 glucuronic acid Drugs 0.000 claims description 3
- 235000006408 oxalic acid Nutrition 0.000 claims description 3
- 238000012216 screening Methods 0.000 claims description 3
- AEMOLEFTQBMNLQ-AQKNRBDQSA-N D-glucopyranuronic acid Chemical compound OC1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O AEMOLEFTQBMNLQ-AQKNRBDQSA-N 0.000 claims 1
- 238000004321 preservation Methods 0.000 abstract description 8
- 239000003795 chemical substances by application Substances 0.000 abstract description 7
- 239000002994 raw material Substances 0.000 abstract description 5
- 239000011248 coating agent Substances 0.000 abstract description 3
- 238000000576 coating method Methods 0.000 abstract description 3
- 238000013268 sustained release Methods 0.000 abstract 2
- 239000012730 sustained-release form Substances 0.000 abstract 2
- 235000003599 food sweetener Nutrition 0.000 description 14
- 239000003765 sweetening agent Substances 0.000 description 14
- 229940093915 gynecological organic acid Drugs 0.000 description 13
- 229920001542 oligosaccharide Polymers 0.000 description 12
- 239000000047 product Substances 0.000 description 11
- 230000000694 effects Effects 0.000 description 10
- 230000036541 health Effects 0.000 description 9
- 229960000583 acetic acid Drugs 0.000 description 8
- 235000007542 Cichorium intybus Nutrition 0.000 description 7
- 244000298479 Cichorium intybus Species 0.000 description 7
- 229920002472 Starch Polymers 0.000 description 7
- 235000013361 beverage Nutrition 0.000 description 7
- 150000002482 oligosaccharides Chemical class 0.000 description 7
- 240000008042 Zea mays Species 0.000 description 6
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 6
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 6
- 238000010521 absorption reaction Methods 0.000 description 6
- 235000005822 corn Nutrition 0.000 description 6
- 239000000284 extract Substances 0.000 description 6
- 239000000796 flavoring agent Substances 0.000 description 6
- 235000013305 food Nutrition 0.000 description 6
- 229920000591 gum Polymers 0.000 description 6
- -1 rice starch Polymers 0.000 description 6
- 238000002360 preparation method Methods 0.000 description 5
- 235000019698 starch Nutrition 0.000 description 5
- 239000008107 starch Substances 0.000 description 5
- 235000020357 syrup Nutrition 0.000 description 5
- 239000006188 syrup Substances 0.000 description 5
- WBZFUFAFFUEMEI-UHFFFAOYSA-M Acesulfame k Chemical compound [K+].CC1=CC(=O)[N-]S(=O)(=O)O1 WBZFUFAFFUEMEI-UHFFFAOYSA-M 0.000 description 4
- 239000001692 EU approved anti-caking agent Substances 0.000 description 4
- 235000010358 acesulfame potassium Nutrition 0.000 description 4
- 229960004998 acesulfame potassium Drugs 0.000 description 4
- 239000000619 acesulfame-K Substances 0.000 description 4
- 239000004480 active ingredient Substances 0.000 description 4
- 230000009286 beneficial effect Effects 0.000 description 4
- 150000001720 carbohydrates Chemical class 0.000 description 4
- 235000014633 carbohydrates Nutrition 0.000 description 4
- 239000000084 colloidal system Substances 0.000 description 4
- 235000013325 dietary fiber Nutrition 0.000 description 4
- 235000021255 galacto-oligosaccharides Nutrition 0.000 description 4
- 150000003271 galactooligosaccharides Chemical class 0.000 description 4
- 239000008187 granular material Substances 0.000 description 4
- 239000000546 pharmaceutical excipient Substances 0.000 description 4
- 235000013406 prebiotics Nutrition 0.000 description 4
- 230000001737 promoting effect Effects 0.000 description 4
- 235000019202 steviosides Nutrition 0.000 description 4
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 description 3
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 3
- 239000004383 Steviol glycoside Substances 0.000 description 3
- 239000004376 Sucralose Substances 0.000 description 3
- 239000013543 active substance Substances 0.000 description 3
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 3
- 239000001768 carboxy methyl cellulose Substances 0.000 description 3
- 239000012141 concentrate Substances 0.000 description 3
- 235000008504 concentrate Nutrition 0.000 description 3
- 239000003651 drinking water Substances 0.000 description 3
- 235000020188 drinking water Nutrition 0.000 description 3
- 235000019634 flavors Nutrition 0.000 description 3
- 235000013355 food flavoring agent Nutrition 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 239000008101 lactose Substances 0.000 description 3
- 235000010413 sodium alginate Nutrition 0.000 description 3
- 239000000661 sodium alginate Substances 0.000 description 3
- 229940005550 sodium alginate Drugs 0.000 description 3
- 238000005507 spraying Methods 0.000 description 3
- 235000019411 steviol glycoside Nutrition 0.000 description 3
- 229930182488 steviol glycoside Natural products 0.000 description 3
- 150000008144 steviol glycosides Chemical class 0.000 description 3
- 238000003860 storage Methods 0.000 description 3
- 235000019408 sucralose Nutrition 0.000 description 3
- BAQAVOSOZGMPRM-QBMZZYIRSA-N sucralose Chemical compound O[C@@H]1[C@@H](O)[C@@H](Cl)[C@@H](CO)O[C@@H]1O[C@@]1(CCl)[C@@H](O)[C@H](O)[C@@H](CCl)O1 BAQAVOSOZGMPRM-QBMZZYIRSA-N 0.000 description 3
- 150000005846 sugar alcohols Chemical class 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 244000215068 Acacia senegal Species 0.000 description 2
- 229920001817 Agar Polymers 0.000 description 2
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 2
- 241000901050 Bifidobacterium animalis subsp. lactis Species 0.000 description 2
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 2
- 241000190633 Cordyceps Species 0.000 description 2
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 2
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 2
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 2
- 229920001353 Dextrin Polymers 0.000 description 2
- 239000004375 Dextrin Substances 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- 239000004386 Erythritol Substances 0.000 description 2
- UNXHWFMMPAWVPI-UHFFFAOYSA-N Erythritol Natural products OCC(O)C(O)CO UNXHWFMMPAWVPI-UHFFFAOYSA-N 0.000 description 2
- 108010010803 Gelatin Proteins 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 description 2
- 235000010469 Glycine max Nutrition 0.000 description 2
- 229920000084 Gum arabic Polymers 0.000 description 2
- 241000186840 Lactobacillus fermentum Species 0.000 description 2
- 241000186606 Lactobacillus gasseri Species 0.000 description 2
- 241000186605 Lactobacillus paracasei Species 0.000 description 2
- 240000006024 Lactobacillus plantarum Species 0.000 description 2
- 235000013965 Lactobacillus plantarum Nutrition 0.000 description 2
- 229930195725 Mannitol Natural products 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 2
- DLRVVLDZNNYCBX-UHFFFAOYSA-N Polydextrose Polymers OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(O)O1 DLRVVLDZNNYCBX-UHFFFAOYSA-N 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 241001409321 Siraitia grosvenorii Species 0.000 description 2
- 229930006000 Sucrose Natural products 0.000 description 2
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 2
- 235000010489 acacia gum Nutrition 0.000 description 2
- 239000000205 acacia gum Substances 0.000 description 2
- WNLRTRBMVRJNCN-UHFFFAOYSA-N adipic acid Chemical compound OC(=O)CCCCC(O)=O WNLRTRBMVRJNCN-UHFFFAOYSA-N 0.000 description 2
- 239000008272 agar Substances 0.000 description 2
- 235000010419 agar Nutrition 0.000 description 2
- IAJILQKETJEXLJ-QTBDOELSSA-N aldehydo-D-glucuronic acid Chemical compound O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)C(O)=O IAJILQKETJEXLJ-QTBDOELSSA-N 0.000 description 2
- 229940009289 bifidobacterium lactis Drugs 0.000 description 2
- RYYVLZVUVIJVGH-UHFFFAOYSA-N caffeine Chemical compound CN1C(=O)N(C)C(=O)C2=C1N=CN2C RYYVLZVUVIJVGH-UHFFFAOYSA-N 0.000 description 2
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 2
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 2
- 235000010418 carrageenan Nutrition 0.000 description 2
- 229920001525 carrageenan Polymers 0.000 description 2
- 239000000679 carrageenan Substances 0.000 description 2
- 229940113118 carrageenan Drugs 0.000 description 2
- CVSVTCORWBXHQV-UHFFFAOYSA-N creatine Chemical compound NC(=[NH2+])N(C)CC([O-])=O CVSVTCORWBXHQV-UHFFFAOYSA-N 0.000 description 2
- 235000019425 dextrin Nutrition 0.000 description 2
- 238000005538 encapsulation Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 235000019414 erythritol Nutrition 0.000 description 2
- 229940009714 erythritol Drugs 0.000 description 2
- UNXHWFMMPAWVPI-ZXZARUISSA-N erythritol Chemical compound OC[C@H](O)[C@H](O)CO UNXHWFMMPAWVPI-ZXZARUISSA-N 0.000 description 2
- 235000019985 fermented beverage Nutrition 0.000 description 2
- 239000008273 gelatin Substances 0.000 description 2
- 229920000159 gelatin Polymers 0.000 description 2
- 235000019322 gelatine Nutrition 0.000 description 2
- 235000011852 gelatine desserts Nutrition 0.000 description 2
- 239000008103 glucose Substances 0.000 description 2
- 230000007407 health benefit Effects 0.000 description 2
- 230000007366 host health Effects 0.000 description 2
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 description 2
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 description 2
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 description 2
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 description 2
- 235000020344 instant tea Nutrition 0.000 description 2
- 239000000832 lactitol Substances 0.000 description 2
- 235000010448 lactitol Nutrition 0.000 description 2
- 229960003451 lactitol Drugs 0.000 description 2
- VQHSOMBJVWLPSR-JVCRWLNRSA-N lactitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-JVCRWLNRSA-N 0.000 description 2
- 229940012969 lactobacillus fermentum Drugs 0.000 description 2
- 229940072205 lactobacillus plantarum Drugs 0.000 description 2
- 229960000511 lactulose Drugs 0.000 description 2
- JCQLYHFGKNRPGE-FCVZTGTOSA-N lactulose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 JCQLYHFGKNRPGE-FCVZTGTOSA-N 0.000 description 2
- PFCRQPBOOFTZGQ-UHFFFAOYSA-N lactulose keto form Natural products OCC(=O)C(O)C(C(O)CO)OC1OC(CO)C(O)C(O)C1O PFCRQPBOOFTZGQ-UHFFFAOYSA-N 0.000 description 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 2
- 230000014759 maintenance of location Effects 0.000 description 2
- 239000000594 mannitol Substances 0.000 description 2
- 235000010355 mannitol Nutrition 0.000 description 2
- 229960001855 mannitol Drugs 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 238000004806 packaging method and process Methods 0.000 description 2
- 239000001814 pectin Substances 0.000 description 2
- 235000010987 pectin Nutrition 0.000 description 2
- 229920001277 pectin Polymers 0.000 description 2
- 239000011734 sodium Substances 0.000 description 2
- 229910052708 sodium Inorganic materials 0.000 description 2
- 239000001509 sodium citrate Substances 0.000 description 2
- 235000010356 sorbitol Nutrition 0.000 description 2
- 239000000600 sorbitol Substances 0.000 description 2
- 229960002920 sorbitol Drugs 0.000 description 2
- 239000005720 sucrose Substances 0.000 description 2
- 235000010491 tara gum Nutrition 0.000 description 2
- 239000000213 tara gum Substances 0.000 description 2
- 235000013616 tea Nutrition 0.000 description 2
- 229940100445 wheat starch Drugs 0.000 description 2
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 description 2
- OMDQUFIYNPYJFM-XKDAHURESA-N (2r,3r,4s,5r,6s)-2-(hydroxymethyl)-6-[[(2r,3s,4r,5s,6r)-4,5,6-trihydroxy-3-[(2s,3s,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]methoxy]oxane-3,4,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O[C@H]2[C@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)[C@H](O)[C@H](O)[C@H](O)O1 OMDQUFIYNPYJFM-XKDAHURESA-N 0.000 description 1
- FYGDTMLNYKFZSV-URKRLVJHSA-N (2s,3r,4s,5s,6r)-2-[(2r,4r,5r,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,4r,5r,6s)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1[C@@H](CO)O[C@@H](OC2[C@H](O[C@H](O)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O FYGDTMLNYKFZSV-URKRLVJHSA-N 0.000 description 1
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 description 1
- SERLAGPUMNYUCK-DCUALPFSSA-N 1-O-alpha-D-glucopyranosyl-D-mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O SERLAGPUMNYUCK-DCUALPFSSA-N 0.000 description 1
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 1
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 description 1
- AEQDJSLRWYMAQI-UHFFFAOYSA-N 2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline Chemical compound C1CN2CC(C(=C(OC)C=C3)OC)=C3CC2C2=C1C=C(OC)C(OC)=C2 AEQDJSLRWYMAQI-UHFFFAOYSA-N 0.000 description 1
- CYDQOEWLBCCFJZ-UHFFFAOYSA-N 4-(4-fluorophenyl)oxane-4-carboxylic acid Chemical compound C=1C=C(F)C=CC=1C1(C(=O)O)CCOCC1 CYDQOEWLBCCFJZ-UHFFFAOYSA-N 0.000 description 1
- 241000208140 Acer Species 0.000 description 1
- 235000009051 Ambrosia paniculata var. peruviana Nutrition 0.000 description 1
- 244000144730 Amygdalus persica Species 0.000 description 1
- 244000099147 Ananas comosus Species 0.000 description 1
- 235000007119 Ananas comosus Nutrition 0.000 description 1
- 235000003097 Artemisia absinthium Nutrition 0.000 description 1
- 240000001851 Artemisia dracunculus Species 0.000 description 1
- 235000017731 Artemisia dracunculus ssp. dracunculus Nutrition 0.000 description 1
- 235000003261 Artemisia vulgaris Nutrition 0.000 description 1
- 108010011485 Aspartame Proteins 0.000 description 1
- 241001061264 Astragalus Species 0.000 description 1
- 241000193749 Bacillus coagulans Species 0.000 description 1
- 229920002498 Beta-glucan Polymers 0.000 description 1
- 241000186000 Bifidobacterium Species 0.000 description 1
- 241000186018 Bifidobacterium adolescentis Species 0.000 description 1
- 241000186016 Bifidobacterium bifidum Species 0.000 description 1
- 241000186012 Bifidobacterium breve Species 0.000 description 1
- 241001608472 Bifidobacterium longum Species 0.000 description 1
- 241000167854 Bourreria succulenta Species 0.000 description 1
- 235000004936 Bromus mango Nutrition 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 229920002101 Chitin Polymers 0.000 description 1
- 229920001661 Chitosan Polymers 0.000 description 1
- 244000223760 Cinnamomum zeylanicum Species 0.000 description 1
- 244000241235 Citrullus lanatus Species 0.000 description 1
- 235000012828 Citrullus lanatus var citroides Nutrition 0.000 description 1
- 235000005979 Citrus limon Nutrition 0.000 description 1
- 244000131522 Citrus pyriformis Species 0.000 description 1
- 241000675108 Citrus tangerina Species 0.000 description 1
- 240000000560 Citrus x paradisi Species 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- 229920002261 Corn starch Polymers 0.000 description 1
- 244000241257 Cucumis melo Species 0.000 description 1
- 235000009847 Cucumis melo var cantalupensis Nutrition 0.000 description 1
- 229920002558 Curdlan Polymers 0.000 description 1
- 239000001879 Curdlan Substances 0.000 description 1
- 229920000858 Cyclodextrin Polymers 0.000 description 1
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 description 1
- 235000019739 Dicalciumphosphate Nutrition 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 239000001329 FEMA 3811 Substances 0.000 description 1
- 240000006927 Foeniculum vulgare Species 0.000 description 1
- 235000004204 Foeniculum vulgare Nutrition 0.000 description 1
- 235000016623 Fragaria vesca Nutrition 0.000 description 1
- 240000009088 Fragaria x ananassa Species 0.000 description 1
- 235000011363 Fragaria x ananassa Nutrition 0.000 description 1
- 229930091371 Fructose Natural products 0.000 description 1
- 239000005715 Fructose Substances 0.000 description 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 1
- 229920000926 Galactomannan Polymers 0.000 description 1
- 229920002148 Gellan gum Polymers 0.000 description 1
- 244000068988 Glycine max Species 0.000 description 1
- 239000004378 Glycyrrhizin Substances 0.000 description 1
- 229920002488 Hemicellulose Polymers 0.000 description 1
- 101001121408 Homo sapiens L-amino-acid oxidase Proteins 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 229920001202 Inulin Polymers 0.000 description 1
- LPHGQDQBBGAPDZ-UHFFFAOYSA-N Isocaffeine Natural products CN1C(=O)N(C)C(=O)C2=C1N(C)C=N2 LPHGQDQBBGAPDZ-UHFFFAOYSA-N 0.000 description 1
- 229920002752 Konjac Polymers 0.000 description 1
- 102100026388 L-amino-acid oxidase Human genes 0.000 description 1
- 240000001046 Lactobacillus acidophilus Species 0.000 description 1
- 235000013956 Lactobacillus acidophilus Nutrition 0.000 description 1
- 240000001929 Lactobacillus brevis Species 0.000 description 1
- 235000013957 Lactobacillus brevis Nutrition 0.000 description 1
- 244000199885 Lactobacillus bulgaricus Species 0.000 description 1
- 235000013960 Lactobacillus bulgaricus Nutrition 0.000 description 1
- 244000199866 Lactobacillus casei Species 0.000 description 1
- 235000013958 Lactobacillus casei Nutrition 0.000 description 1
- 240000002605 Lactobacillus helveticus Species 0.000 description 1
- 235000013967 Lactobacillus helveticus Nutrition 0.000 description 1
- 241001468157 Lactobacillus johnsonii Species 0.000 description 1
- 241000186684 Lactobacillus pentosus Species 0.000 description 1
- 241000186604 Lactobacillus reuteri Species 0.000 description 1
- 241000218588 Lactobacillus rhamnosus Species 0.000 description 1
- 241000186869 Lactobacillus salivarius Species 0.000 description 1
- 229920000161 Locust bean gum Polymers 0.000 description 1
- 229920002774 Maltodextrin Polymers 0.000 description 1
- 239000005913 Maltodextrin Substances 0.000 description 1
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 description 1
- 241000220225 Malus Species 0.000 description 1
- 235000011430 Malus pumila Nutrition 0.000 description 1
- 235000015103 Malus silvestris Nutrition 0.000 description 1
- 235000014826 Mangifera indica Nutrition 0.000 description 1
- 240000007228 Mangifera indica Species 0.000 description 1
- 229920000168 Microcrystalline cellulose Polymers 0.000 description 1
- 240000005561 Musa balbisiana Species 0.000 description 1
- 235000018290 Musa x paradisiaca Nutrition 0.000 description 1
- 208000008589 Obesity Diseases 0.000 description 1
- 208000001132 Osteoporosis Diseases 0.000 description 1
- 235000000370 Passiflora edulis Nutrition 0.000 description 1
- 244000288157 Passiflora edulis Species 0.000 description 1
- 241000191998 Pediococcus acidilactici Species 0.000 description 1
- 241000191996 Pediococcus pentosaceus Species 0.000 description 1
- 235000010627 Phaseolus vulgaris Nutrition 0.000 description 1
- 244000046052 Phaseolus vulgaris Species 0.000 description 1
- 229920001100 Polydextrose Polymers 0.000 description 1
- HLCFGWHYROZGBI-JJKGCWMISA-M Potassium gluconate Chemical compound [K+].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O HLCFGWHYROZGBI-JJKGCWMISA-M 0.000 description 1
- XBDQKXXYIPTUBI-UHFFFAOYSA-M Propionate Chemical compound CCC([O-])=O XBDQKXXYIPTUBI-UHFFFAOYSA-M 0.000 description 1
- 235000006040 Prunus persica var persica Nutrition 0.000 description 1
- 235000014443 Pyrus communis Nutrition 0.000 description 1
- MUPFEKGTMRGPLJ-RMMQSMQOSA-N Raffinose Natural products O(C[C@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@@H](O[C@@]2(CO)[C@H](O)[C@@H](O)[C@@H](CO)O2)O1)[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 MUPFEKGTMRGPLJ-RMMQSMQOSA-N 0.000 description 1
- 229920000294 Resistant starch Polymers 0.000 description 1
- 108010073771 Soybean Proteins Proteins 0.000 description 1
- 235000009184 Spondias indica Nutrition 0.000 description 1
- UEDUENGHJMELGK-HYDKPPNVSA-N Stevioside Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O UEDUENGHJMELGK-HYDKPPNVSA-N 0.000 description 1
- 241000194017 Streptococcus Species 0.000 description 1
- 244000057717 Streptococcus lactis Species 0.000 description 1
- 235000014897 Streptococcus lactis Nutrition 0.000 description 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 1
- 244000299461 Theobroma cacao Species 0.000 description 1
- MUPFEKGTMRGPLJ-UHFFFAOYSA-N UNPD196149 Natural products OC1C(O)C(CO)OC1(CO)OC1C(O)C(O)C(O)C(COC2C(C(O)C(O)C(CO)O2)O)O1 MUPFEKGTMRGPLJ-UHFFFAOYSA-N 0.000 description 1
- 235000009499 Vanilla fragrans Nutrition 0.000 description 1
- 244000263375 Vanilla tahitensis Species 0.000 description 1
- 235000012036 Vanilla tahitensis Nutrition 0.000 description 1
- 235000009754 Vitis X bourquina Nutrition 0.000 description 1
- 235000012333 Vitis X labruscana Nutrition 0.000 description 1
- 240000006365 Vitis vinifera Species 0.000 description 1
- 235000014787 Vitis vinifera Nutrition 0.000 description 1
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 description 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000001361 adipic acid Substances 0.000 description 1
- 235000011037 adipic acid Nutrition 0.000 description 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 1
- 235000001014 amino acid Nutrition 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 239000001138 artemisia absinthium Substances 0.000 description 1
- 239000008122 artificial sweetener Substances 0.000 description 1
- 235000021311 artificial sweeteners Nutrition 0.000 description 1
- 239000000605 aspartame Substances 0.000 description 1
- 235000010357 aspartame Nutrition 0.000 description 1
- IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 description 1
- 229960003438 aspartame Drugs 0.000 description 1
- 235000006533 astragalus Nutrition 0.000 description 1
- 229940054340 bacillus coagulans Drugs 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 235000021028 berry Nutrition 0.000 description 1
- GUBGYTABKSRVRQ-QUYVBRFLSA-N beta-maltose Chemical compound OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O GUBGYTABKSRVRQ-QUYVBRFLSA-N 0.000 description 1
- 229940002008 bifidobacterium bifidum Drugs 0.000 description 1
- 229940009291 bifidobacterium longum Drugs 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 229960001948 caffeine Drugs 0.000 description 1
- VJEONQKOZGKCAK-UHFFFAOYSA-N caffeine Natural products CN1C(=O)N(C)C(=O)C2=C1C=CN2C VJEONQKOZGKCAK-UHFFFAOYSA-N 0.000 description 1
- 239000001506 calcium phosphate Substances 0.000 description 1
- 235000021466 carotenoid Nutrition 0.000 description 1
- 150000001747 carotenoids Chemical class 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 235000019693 cherries Nutrition 0.000 description 1
- 235000019219 chocolate Nutrition 0.000 description 1
- 235000017803 cinnamon Nutrition 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 239000013065 commercial product Substances 0.000 description 1
- 239000008120 corn starch Substances 0.000 description 1
- 229940099112 cornstarch Drugs 0.000 description 1
- 229960003624 creatine Drugs 0.000 description 1
- 239000006046 creatine Substances 0.000 description 1
- 235000019316 curdlan Nutrition 0.000 description 1
- 229940078035 curdlan Drugs 0.000 description 1
- HEBKCHPVOIAQTA-NGQZWQHPSA-N d-xylitol Chemical compound OC[C@H](O)C(O)[C@H](O)CO HEBKCHPVOIAQTA-NGQZWQHPSA-N 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- NEFBYIFKOOEVPA-UHFFFAOYSA-K dicalcium phosphate Chemical compound [Ca+2].[Ca+2].[O-]P([O-])([O-])=O NEFBYIFKOOEVPA-UHFFFAOYSA-K 0.000 description 1
- 229940038472 dicalcium phosphate Drugs 0.000 description 1
- 229910000390 dicalcium phosphate Inorganic materials 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000005265 energy consumption Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 229930003935 flavonoid Natural products 0.000 description 1
- 235000017173 flavonoids Nutrition 0.000 description 1
- 150000002215 flavonoids Chemical class 0.000 description 1
- 235000012041 food component Nutrition 0.000 description 1
- 239000005417 food ingredient Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 235000010492 gellan gum Nutrition 0.000 description 1
- 239000000216 gellan gum Substances 0.000 description 1
- 239000012362 glacial acetic acid Substances 0.000 description 1
- 229950006191 gluconic acid Drugs 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 229960002449 glycine Drugs 0.000 description 1
- 235000013905 glycine and its sodium salt Nutrition 0.000 description 1
- LPLVUJXQOOQHMX-UHFFFAOYSA-N glycyrrhetinic acid glycoside Natural products C1CC(C2C(C3(CCC4(C)CCC(C)(CC4C3=CC2=O)C(O)=O)C)(C)CC2)(C)C2C(C)(C)C1OC1OC(C(O)=O)C(O)C(O)C1OC1OC(C(O)=O)C(O)C(O)C1O LPLVUJXQOOQHMX-UHFFFAOYSA-N 0.000 description 1
- 229960004949 glycyrrhizic acid Drugs 0.000 description 1
- UYRUBYNTXSDKQT-UHFFFAOYSA-N glycyrrhizic acid Natural products CC1(C)C(CCC2(C)C1CCC3(C)C2C(=O)C=C4C5CC(C)(CCC5(C)CCC34C)C(=O)O)OC6OC(C(O)C(O)C6OC7OC(O)C(O)C(O)C7C(=O)O)C(=O)O UYRUBYNTXSDKQT-UHFFFAOYSA-N 0.000 description 1
- 235000019410 glycyrrhizin Nutrition 0.000 description 1
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 description 1
- 235000021552 granulated sugar Nutrition 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 235000012907 honey Nutrition 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 229940029339 inulin Drugs 0.000 description 1
- JYJIGFIDKWBXDU-MNNPPOADSA-N inulin Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)OC[C@]1(OC[C@]2(OC[C@]3(OC[C@]4(OC[C@]5(OC[C@]6(OC[C@]7(OC[C@]8(OC[C@]9(OC[C@]%10(OC[C@]%11(OC[C@]%12(OC[C@]%13(OC[C@]%14(OC[C@]%15(OC[C@]%16(OC[C@]%17(OC[C@]%18(OC[C@]%19(OC[C@]%20(OC[C@]%21(OC[C@]%22(OC[C@]%23(OC[C@]%24(OC[C@]%25(OC[C@]%26(OC[C@]%27(OC[C@]%28(OC[C@]%29(OC[C@]%30(OC[C@]%31(OC[C@]%32(OC[C@]%33(OC[C@]%34(OC[C@]%35(OC[C@]%36(O[C@@H]%37[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O%37)O)[C@H]([C@H](O)[C@@H](CO)O%36)O)[C@H]([C@H](O)[C@@H](CO)O%35)O)[C@H]([C@H](O)[C@@H](CO)O%34)O)[C@H]([C@H](O)[C@@H](CO)O%33)O)[C@H]([C@H](O)[C@@H](CO)O%32)O)[C@H]([C@H](O)[C@@H](CO)O%31)O)[C@H]([C@H](O)[C@@H](CO)O%30)O)[C@H]([C@H](O)[C@@H](CO)O%29)O)[C@H]([C@H](O)[C@@H](CO)O%28)O)[C@H]([C@H](O)[C@@H](CO)O%27)O)[C@H]([C@H](O)[C@@H](CO)O%26)O)[C@H]([C@H](O)[C@@H](CO)O%25)O)[C@H]([C@H](O)[C@@H](CO)O%24)O)[C@H]([C@H](O)[C@@H](CO)O%23)O)[C@H]([C@H](O)[C@@H](CO)O%22)O)[C@H]([C@H](O)[C@@H](CO)O%21)O)[C@H]([C@H](O)[C@@H](CO)O%20)O)[C@H]([C@H](O)[C@@H](CO)O%19)O)[C@H]([C@H](O)[C@@H](CO)O%18)O)[C@H]([C@H](O)[C@@H](CO)O%17)O)[C@H]([C@H](O)[C@@H](CO)O%16)O)[C@H]([C@H](O)[C@@H](CO)O%15)O)[C@H]([C@H](O)[C@@H](CO)O%14)O)[C@H]([C@H](O)[C@@H](CO)O%13)O)[C@H]([C@H](O)[C@@H](CO)O%12)O)[C@H]([C@H](O)[C@@H](CO)O%11)O)[C@H]([C@H](O)[C@@H](CO)O%10)O)[C@H]([C@H](O)[C@@H](CO)O9)O)[C@H]([C@H](O)[C@@H](CO)O8)O)[C@H]([C@H](O)[C@@H](CO)O7)O)[C@H]([C@H](O)[C@@H](CO)O6)O)[C@H]([C@H](O)[C@@H](CO)O5)O)[C@H]([C@H](O)[C@@H](CO)O4)O)[C@H]([C@H](O)[C@@H](CO)O3)O)[C@H]([C@H](O)[C@@H](CO)O2)O)[C@@H](O)[C@H](O)[C@@H](CO)O1 JYJIGFIDKWBXDU-MNNPPOADSA-N 0.000 description 1
- 239000000905 isomalt Substances 0.000 description 1
- 235000010439 isomalt Nutrition 0.000 description 1
- HPIGCVXMBGOWTF-UHFFFAOYSA-N isomaltol Natural products CC(=O)C=1OC=CC=1O HPIGCVXMBGOWTF-UHFFFAOYSA-N 0.000 description 1
- DLRVVLDZNNYCBX-RTPHMHGBSA-N isomaltose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)C(O)O1 DLRVVLDZNNYCBX-RTPHMHGBSA-N 0.000 description 1
- 235000015110 jellies Nutrition 0.000 description 1
- 239000008274 jelly Substances 0.000 description 1
- 239000000252 konjac Substances 0.000 description 1
- 235000019823 konjac gum Nutrition 0.000 description 1
- 229940039695 lactobacillus acidophilus Drugs 0.000 description 1
- 229940004208 lactobacillus bulgaricus Drugs 0.000 description 1
- 229940017800 lactobacillus casei Drugs 0.000 description 1
- 229940054346 lactobacillus helveticus Drugs 0.000 description 1
- 229940001882 lactobacillus reuteri Drugs 0.000 description 1
- 235000010445 lecithin Nutrition 0.000 description 1
- 239000000787 lecithin Substances 0.000 description 1
- 229940067606 lecithin Drugs 0.000 description 1
- 229920005610 lignin Polymers 0.000 description 1
- 235000010420 locust bean gum Nutrition 0.000 description 1
- 239000000711 locust bean gum Substances 0.000 description 1
- 235000019359 magnesium stearate Nutrition 0.000 description 1
- 229940035034 maltodextrin Drugs 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 239000008108 microcrystalline cellulose Substances 0.000 description 1
- 235000019813 microcrystalline cellulose Nutrition 0.000 description 1
- 229940016286 microcrystalline cellulose Drugs 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- ITVGXXMINPYUHD-CUVHLRMHSA-N neohesperidin dihydrochalcone Chemical compound C1=C(O)C(OC)=CC=C1CCC(=O)C(C(=C1)O)=C(O)C=C1O[C@H]1[C@H](O[C@H]2[C@@H]([C@H](O)[C@@H](O)[C@H](C)O2)O)[C@@H](O)[C@H](O)[C@@H](CO)O1 ITVGXXMINPYUHD-CUVHLRMHSA-N 0.000 description 1
- 229940089953 neohesperidin dihydrochalcone Drugs 0.000 description 1
- 235000010434 neohesperidine DC Nutrition 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 235000020824 obesity Nutrition 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 229960004838 phosphoric acid Drugs 0.000 description 1
- 235000011007 phosphoric acid Nutrition 0.000 description 1
- 239000003075 phytoestrogen Substances 0.000 description 1
- 239000000419 plant extract Substances 0.000 description 1
- 235000002378 plant sterols Nutrition 0.000 description 1
- 235000013856 polydextrose Nutrition 0.000 description 1
- 239000001259 polydextrose Substances 0.000 description 1
- 229940035035 polydextrose Drugs 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 239000004224 potassium gluconate Substances 0.000 description 1
- 229960003189 potassium gluconate Drugs 0.000 description 1
- 235000013926 potassium gluconate Nutrition 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- MUPFEKGTMRGPLJ-ZQSKZDJDSA-N raffinose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O2)O)O1 MUPFEKGTMRGPLJ-ZQSKZDJDSA-N 0.000 description 1
- 238000005057 refrigeration Methods 0.000 description 1
- 235000021254 resistant starch Nutrition 0.000 description 1
- 229940100486 rice starch Drugs 0.000 description 1
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 235000019615 sensations Nutrition 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- HELHAJAZNSDZJO-OLXYHTOASA-L sodium L-tartrate Chemical compound [Na+].[Na+].[O-]C(=O)[C@H](O)[C@@H](O)C([O-])=O HELHAJAZNSDZJO-OLXYHTOASA-L 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- 239000000176 sodium gluconate Substances 0.000 description 1
- 229940005574 sodium gluconate Drugs 0.000 description 1
- 235000012207 sodium gluconate Nutrition 0.000 description 1
- 239000001540 sodium lactate Substances 0.000 description 1
- 235000011088 sodium lactate Nutrition 0.000 description 1
- 229940005581 sodium lactate Drugs 0.000 description 1
- 239000001433 sodium tartrate Substances 0.000 description 1
- 229960002167 sodium tartrate Drugs 0.000 description 1
- 235000011004 sodium tartrates Nutrition 0.000 description 1
- KZQSXALQTHVPDQ-UHFFFAOYSA-M sodium;butanedioate;hydron Chemical compound [Na+].OC(=O)CCC([O-])=O KZQSXALQTHVPDQ-UHFFFAOYSA-M 0.000 description 1
- 229940001941 soy protein Drugs 0.000 description 1
- 235000013599 spices Nutrition 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 229940013618 stevioside Drugs 0.000 description 1
- OHHNJQXIOPOJSC-UHFFFAOYSA-N stevioside Natural products CC1(CCCC2(C)C3(C)CCC4(CC3(CCC12C)CC4=C)OC5OC(CO)C(O)C(O)C5OC6OC(CO)C(O)C(O)C6O)C(=O)OC7OC(CO)C(O)C(O)C7O OHHNJQXIOPOJSC-UHFFFAOYSA-N 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 210000004233 talus Anatomy 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 229960001367 tartaric acid Drugs 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 description 1
- 229940038773 trisodium citrate Drugs 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 239000000811 xylitol Substances 0.000 description 1
- 235000010447 xylitol Nutrition 0.000 description 1
- 229960002675 xylitol Drugs 0.000 description 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
Images
Landscapes
- Tea And Coffee (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Description
本揭露係關於一種顆粒結構,尤係關於一種包埋有機酸之顆粒結構。 The present disclosure relates to a particle structure, and more particularly to a particle structure encapsulating an organic acid.
含有機酸成分之飲品在進行粉末化之過程常使用高溫噴霧乾燥;然而,產品中的有機酸容易因高溫而被破壞或揮發逸散,因此無法有效達到保留有機酸以作為保健品的成分。再者,自製發酵飲品保存階段的低溫冷藏效期多僅能保存1周,且保存過程不可避免地將產生能耗成本。 Beverages containing organic acids are often dried by high-temperature spraying during the powdering process; however, the organic acids in the product are easily destroyed or volatilized by high temperatures, so it is not possible to effectively retain the organic acids as ingredients for health products. Furthermore, the low-temperature refrigeration period of homemade fermented beverages can only be preserved for 1 week at most, and the preservation process will inevitably generate energy consumption costs.
此外,為了增加產品溶解度,一般即溶粉末飲品係以不同配方組成的粉末混合而得,因其混拌過程中易產生吸濕的問題,故配方中常添加二氧化矽作為抗結塊劑。然而,抗結塊劑對於食用者之健康無益,食用過量反而造成身體負擔。 In addition, in order to increase the solubility of the product, instant powdered drinks are generally made by mixing powders of different formulas. Since the mixing process is prone to moisture absorption, silicon dioxide is often added to the formula as an anti-caking agent. However, anti-caking agents are not good for the health of consumers, and excessive consumption will cause a burden on the body.
因此,本領域亟需可同時克服上述問題的產品。 Therefore, this field is in urgent need of products that can overcome the above problems at the same time.
有鑑於上述問題,本揭露提供一種能包埋有機酸及其它活性物質之顆粒結構,其包含核心、包覆該核心的調味殼層及包覆該調味殼層的保護層,其中,該核心包含功能性成分,且該功能性成分包含纖維和紅茶菌菇發酵液。 In view of the above problems, the present disclosure provides a particle structure capable of encapsulating organic acids and other active substances, which comprises a core, a flavoring shell layer covering the core, and a protective layer covering the flavoring shell layer, wherein the core comprises functional ingredients, and the functional ingredients comprise fiber and kombucha mushroom fermentation liquid.
於本揭露之至少一具體實施例中,該核心進一步包含紅茶粉。 In at least one specific embodiment of the present disclosure, the core further comprises black tea powder.
於本揭露之至少一具體實施例中,該顆粒結構之平均粒徑至少為0.2mm。於本揭露之一些具體實施例中,該顆粒結構之平均粒徑為0.2mm至0.5mm。 In at least one specific embodiment of the present disclosure, the average particle size of the particle structure is at least 0.2 mm. In some specific embodiments of the present disclosure, the average particle size of the particle structure is 0.2 mm to 0.5 mm.
於本揭露之至少一具體實施例中,該纖維係選自由可溶性纖維、菊苣纖維、果寡糖所組成群組之其中之一或其組合。 In at least one specific embodiment of the present disclosure, the fiber is selected from one of the group consisting of soluble fiber, chicory fiber, and fructooligosaccharide or a combination thereof.
於本揭露之至少一具體實施例中,該功能性成分另包含幫助保存有機酸之有效成分、載劑、賦形劑或其組合。 In at least one specific embodiment of the present disclosure, the functional ingredient further comprises an active ingredient that helps preserve organic acids, a carrier, a formulator, or a combination thereof.
於本揭露之至少一具體實施例中,該紅茶菌菇發酵液包含有機酸或益生菌。於本揭露之一些具體實施例中,該益生菌為乳酸菌。 In at least one specific embodiment of the present disclosure, the fermented Kombucha mushroom liquid contains organic acid or probiotics. In some specific embodiments of the present disclosure, the probiotics are lactic acid bacteria.
於本揭露之至少一具體實施例中,該有機酸係選自由醋酸、檸檬酸、琥珀酸、草酸、葡萄糖醛酸及葡萄糖酸所組成群組之其中之一或其組合。 In at least one specific embodiment of the present disclosure, the organic acid is selected from one or a combination of the group consisting of acetic acid, citric acid, succinic acid, oxalic acid, glucuronic acid and gluconic acid.
於本揭露之至少一具體實施例中,該調味殼層包含香氣微膠囊及調味成分。 In at least one specific embodiment of the present disclosure, the flavoring shell comprises aroma microcapsules and flavoring ingredients.
於本揭露的一些具體實施例中,該核心係由紅茶菌菇發酵液經噴霧造粒而製成,故能有效防止紅茶菌菇發酵液中的有機酸成分被破壞或揮發逸散,且將粉體原料製備成顆粒狀能改善粉體的流動性及溶解性。 此外,調味殼層除了具有調味或調香成分,還具有保護包埋其中有機酸成分之功效,亦可視實際需求設計為緩釋型調味殼層。另外,保護層具有抗吸濕功能,以取代一般粉末混拌工段所添加的抗結塊劑。 In some specific embodiments disclosed herein, the core is made of kombucha fermented liquid by spray granulation, so that the organic acid components in the kombucha fermented liquid can be effectively prevented from being destroyed or volatilized, and the powder raw material is prepared into granules to improve the fluidity and solubility of the powder. In addition, the seasoning shell layer not only has the flavoring or fragrance components, but also has the effect of protecting and encapsulating the organic acid components therein, and can also be designed as a slow-release seasoning shell layer according to actual needs. In addition, the protective layer has an anti-moisture absorption function to replace the anti-caking agent added in the general powder mixing stage.
本揭露另提供一種製備上述顆粒結構之方法,其包含將該功能性成分過篩;混合及乾燥該功能性成分;將該功能性成分進行噴霧造粒以形成該核心;以及形成包覆該核心之調味殼層及保護層。 The present disclosure also provides a method for preparing the above-mentioned particle structure, which comprises screening the functional ingredients; mixing and drying the functional ingredients; spraying and granulating the functional ingredients to form the core; and forming a flavoring shell layer and a protective layer covering the core.
於本揭露之至少一具體實施例中,該紅茶菌菇發酵液係藉由噴霧造粒以形成該核心。於本揭露之一些具體實施例中,係使用流動床噴霧造粒製程將該紅茶粉、纖維和紅茶菌菇發酵液或其他功能性成分快速且均勻包覆混合。 In at least one specific embodiment of the present disclosure, the fermented kombucha mushroom liquid is granulated by spraying to form the core. In some specific embodiments of the present disclosure, the black tea powder, fiber and fermented kombucha mushroom liquid or other functional ingredients are quickly and evenly coated and mixed using a fluidized bed spray granulation process.
於本揭露之至少一具體實施例中,該噴霧造粒之溫度為30℃至90℃、37℃至43℃、40℃至80℃、77℃至83℃、52℃至74℃、57℃至63℃、49℃至62℃或61℃至69℃。於一些具體實施例中,該噴霧造粒之溫度可為約31℃、33℃、35℃、37℃、39℃、41℃、43℃、45℃、47℃、49℃、51℃、53℃、55℃、57℃、59℃、61℃、63℃、65℃、67℃、69℃、71℃、73℃、75℃、77℃、79℃、81℃、83℃、85℃、87℃、89℃,但本揭露不以此為限。 In at least one specific embodiment of the present disclosure, the temperature of the spray granulation is 30°C to 90°C, 37°C to 43°C, 40°C to 80°C, 77°C to 83°C, 52°C to 74°C, 57°C to 63°C, 49°C to 62°C, or 61°C to 69°C. In some specific embodiments, the temperature of the spray granulation may be about 31°C, 33°C, 35°C, 37°C, 39°C, 41°C, 43°C, 45°C, 47°C, 49°C, 51°C, 53°C, 55°C, 57°C, 59°C, 61°C, 63°C, 65°C, 67°C, 69°C, 71°C, 73°C, 75°C, 77°C, 79°C, 81°C, 83°C, 85°C, 87°C, 89°C, but the present disclosure is not limited thereto.
於本揭露之至少一具體實施例中,係使用流動床噴霧造粒機以約57℃至63℃進行顆粒原料混拌與包覆造粒,該顆粒原料包含纖維和紅茶菌菇發酵液;在核心表面以調味成分做包覆形成調味殼層;以及在該調味殼層之外層以再以包埋技術形成保護層。於本揭露的一些具體實施例中,該保護層為抗吸濕保護層,以形成微膠囊顆粒之設計,故無需額外添 加抗結塊劑。 In at least one specific embodiment of the present disclosure, a fluidized bed spray granulator is used to mix and coat the granule raw materials at about 57°C to 63°C. The granule raw materials include fiber and fermented tea mushroom liquid; a flavoring shell is formed by coating the core surface with a flavoring component; and a protective layer is formed on the outer layer of the flavoring shell by an embedding technique. In some specific embodiments of the present disclosure, the protective layer is an anti-hygroscopic protective layer to form a microcapsule particle design, so there is no need to add an anti-caking agent.
本揭露之顆粒結構較一般紅茶菌菇飲品產品結構均勻,故可改善粉體之流動性與溶解性。此外,本揭露所採用之特定溫度範圍的噴霧造粒製程,除了保留有機酸成分外,還在表面以調味成分做包覆形成調味殼層,包埋並保護其有機酸成分,最後以包覆形成保護層進行微膠囊顆粒的設計,以取代一般粉末混拌工段所添加的抗結塊劑,達到粉末的抗吸濕之保存性。整體而言,本揭露改善即溶茶飲品粉體之均勻性,並提升其流動性與即溶沖泡下的溶解性;以特定溫度包埋與保存發酵紅茶菌菇中的機能有機酸成分,以達到健康化的效果;提升即溶茶飲品的抗吸濕與保存性,無添加抗結塊劑的配方組合符合食品潔淨標籤(Clean label)的演進概念,強化保健品的健康價值。 The particle structure of the present invention is more uniform than that of general kombucha mushroom drink products, so the fluidity and solubility of the powder can be improved. In addition, the spray granulation process in a specific temperature range adopted by the present invention not only retains the organic acid components, but also forms a flavoring shell layer on the surface with a flavoring component to embed and protect the organic acid components. Finally, the microcapsule particles are designed with a protective layer formed by coating to replace the anti-caking agent added in the general powder mixing stage, so as to achieve the anti-hygroscopic preservation of the powder. In general, the present invention improves the uniformity of instant tea powder, and enhances its fluidity and solubility under instant brewing; embeds and preserves the functional organic acid components in fermented kombucha mushrooms at a specific temperature to achieve a health-enhancing effect; enhances the moisture absorption resistance and preservation of instant tea, and the formula combination without adding anti-caking agents complies with the evolution concept of food clean label (Clean label), enhancing the health value of health products.
本揭露之顆粒結構可直接添加至飲用水或其他飲品中,以增添風味。當本揭露之顆粒結構接觸飲品後,該顆粒結構之調味殼層可使功能性成分及調味劑釋放。於本案之一具體實施例中,該保護層接觸該飲品後將產生崩解、分解或溶解,使該功能性成分及該調味劑釋放於該飲品中。該功能性成分例如有機酸及纖維,有益於食用者之身體健康,且該功能性成分還可包括促進保存有機酸之有效成分,有益於促進吸收有機酸。此外,本揭露減少使用抗結塊劑,以包埋技術取代一般粉末混拌工段所添加的抗結塊劑,達到粉末的抗吸濕之保存性,因此增加整體保存時間。 The particle structure disclosed herein can be directly added to drinking water or other beverages to add flavor. When the particle structure disclosed herein contacts the beverage, the flavoring shell layer of the particle structure can release the functional ingredients and flavoring. In a specific embodiment of the present case, the protective layer will disintegrate, decompose or dissolve after contacting the beverage, so that the functional ingredients and the flavoring are released into the beverage. The functional ingredients, such as organic acids and fibers, are beneficial to the health of the consumer, and the functional ingredients may also include active ingredients that promote the preservation of organic acids, which are beneficial to promoting the absorption of organic acids. In addition, the present invention reduces the use of anti-caking agents and uses encapsulation technology to replace the anti-caking agents added in the general powder mixing stage, thereby achieving the anti-hygroscopic preservation of the powder, thereby increasing the overall shelf life.
因此,本揭露之顆粒結構可兼顧飲品之方便性、健康益處及保存效果,強化作為保健品的健康價值。 Therefore, the particle structure disclosed herein can take into account the convenience, health benefits and preservation effects of the beverage, and enhance the health value as a health product.
100:顆粒結構 100: Particle structure
11:紅茶粉 11: Black tea powder
12:纖維 12: Fiber
13:紅茶菌菇發酵液 13: Kombucha mushroom fermented liquid
21:香氣微膠囊 21: Aroma microcapsule
22:調味殼層 22: Seasoning the crust
23:保護層 23: Protective layer
圖1係本揭露之一具體實施例中製備顆粒結構的方法流程圖。 Figure 1 is a flow chart of a method for preparing a particle structure in one specific embodiment of the present disclosure.
圖2係本揭露之一具體實施例中之顆粒結構的剖面示意圖。 Figure 2 is a schematic cross-sectional view of a particle structure in one specific embodiment of the present disclosure.
以下係藉由特定的具體實施例說明本揭露之實施方式,本揭露所屬技術領域中具有通常知識者可依據本說明書所揭示之內容輕易地瞭解本揭露之精神、優點及功效。然而,本揭露之具體實施例並非用以限定本揭露,本揭露亦可藉由其它不同之實施方式加以實現或應用,本說明書所載各項細節亦可根據不同的觀點與應用,在不悖離本揭露之精神下賦予不同的變化或修飾。 The following is a specific embodiment to illustrate the implementation of the present disclosure. Those with ordinary knowledge in the technical field to which the present disclosure belongs can easily understand the spirit, advantages and effects of the present disclosure based on the content disclosed in this manual. However, the specific embodiment of the present disclosure is not used to limit the present disclosure. The present disclosure can also be implemented or applied through other different implementation methods. The details contained in this manual can also be given different changes or modifications based on different viewpoints and applications without deviating from the spirit of the present disclosure.
本文所述「包括」或「包含」組成分或步驟時,除非另有說明,否則可另包含其他組成分或其他步驟,而非排除該等其他組成分或其他步驟。此外,除非本文另有明確說明,否則本文所述單數形式之「一」及「該」包含複數指示物,且本文所述「或」係與「及/或」互換使用。 When "including" or "comprising" components or steps are described herein, other components or other steps may be included, but such other components or other steps are not excluded, unless otherwise specified herein. In addition, unless otherwise clearly specified herein, the singular forms "a", "an" and "the" described herein include plural referents, and "or" described herein is used interchangeably with "and/or".
本文所述之數值範圍係包含及可合併的,落在本文所述數值範圍內之任何數值,都可以作為最大值或最小值以導出次範圍;舉例而言,「0.2mm至0.5mm」之數值範圍應可理解為包含最小值0.2mm及最大值0.5mm之間的任何次範圍,例如:0.2mm至0.4mm、0.3mm至0.5mm及0.35mm至0.45mm等次範圍。此外,本文所述的多個數值可以選擇性被選為最大值或最小值以導出數值範圍;舉例而言,41℃、53℃、65℃ 可以導出41℃至53℃、41℃至65℃、53℃至65℃的數值範圍。另外,本文所述之百分比符號「%」,除非另有特別說明,否則表示重量百分比。 The numerical ranges described herein are inclusive and combinable. Any numerical value falling within the numerical range described herein can be used as the maximum or minimum value to derive a sub-range. For example, the numerical range of "0.2mm to 0.5mm" should be understood to include any sub-range between the minimum value of 0.2mm and the maximum value of 0.5mm, such as: 0.2mm to 0.4mm, 0.3mm to 0.5mm, and 0.35mm to 0.45mm. In addition, the multiple numerical values described herein can be selectively selected as the maximum or minimum value to derive a numerical range; for example, 41℃, 53℃, 65℃ can derive a numerical range of 41℃ to 53℃, 41℃ to 65℃, and 53℃ to 65℃. In addition, the percentage symbol "%" described herein, unless otherwise specified, represents weight percentage.
如本文中所使用,術語「約」通常係指數值旨在包含於給定的數值或範圍具有±20%、±10%、±5%、±1%、±0.5%、±0.1%的偏差。該數值偏差可因為,如實驗誤差;製備化合物、組成物、濃縮物、配方之測量標準誤或處理流程;本揭露之來源、製造、起始材料或成分的純度;類似的考量因素而出現。或者,當由所屬領域具中具有通常知識者考量時,術語「約」意指介於可接受的平均值的標準誤差內。除非明確地界定,所有數值範圍、量、數值、比例像是於本文中所揭露的材料、時段的持續時間、溫度、執行的條件、含量的比例、其類似物之定量,應理解為在所有情況下皆由術語「約」修飾。 As used herein, the term "about" generally means that the numerical value is intended to include a deviation of ±20%, ±10%, ±5%, ±1%, ±0.5%, ±0.1% from the given numerical value or range. Such numerical deviations may occur due to, for example, experimental errors; measurement standard errors or process flows in preparing compounds, compositions, concentrates, formulations; the purity of the source, manufacture, starting materials or components of the present disclosure; and similar considerations. Alternatively, when considered by one of ordinary skill in the art, the term "about" means within the standard error of an acceptable mean. Unless expressly defined otherwise, all numerical ranges, amounts, values, ratios, such as materials, durations of time, temperatures, conditions of execution, ratios of contents, and the like disclosed herein, should be understood to be modified in all cases by the term "about".
本揭露包埋有機酸及活性物質之顆粒結構包含核心、調味殼層及保護層,其中,該核心包含功能性成分,且該功能性成分可包含幫助保存有機酸之有效成分、載劑、賦形劑或其組合;該調味殼層包覆該核心;該保護層包覆整個顆粒結構。 The disclosed particle structure encapsulating organic acids and active substances comprises a core, a flavoring shell layer and a protective layer, wherein the core comprises a functional ingredient, and the functional ingredient may comprise an active ingredient that helps preserve the organic acid, a carrier, a formulator or a combination thereof; the flavoring shell layer encapsulates the core; and the protective layer encapsulates the entire particle structure.
本揭露用於製備包埋有機酸及活性物質之顆粒結構的方法包含:將功能性成分與載劑或賦形劑混合,將顆粒原料製成均勻的顆粒狀和核心,其中,該功能性成分包含纖維和紅茶菌菇發酵液;以及在該核心之表面以調味成分形成調味殼層,以包覆該核心;最後,以包埋技術完成保護層以包覆該調味殼層。上述載劑或賦形劑為食品上或生理上可接受之載劑或賦形劑。 The method disclosed herein for preparing a particle structure encapsulating organic acids and active substances comprises: mixing a functional ingredient with a carrier or a formulator, making the particle raw material into a uniform particle shape and a core, wherein the functional ingredient comprises fiber and fermented tea mushroom liquid; and forming a flavoring shell layer on the surface of the core with a flavoring ingredient to coat the core; finally, completing a protective layer with an encapsulation technique to coat the flavoring shell layer. The above-mentioned carrier or formulator is a carrier or formulator that is acceptable to food or physiologically.
於本揭露之一具體實施例中,該顆粒結構幫助保存有機酸, 故有益於促進吸收有機酸,該顆粒結構包含以下:核心、調味殼層及保護層。較佳地,平均粒徑為至少0.2mm。於本揭露之另一具體實施例中,該顆粒結構之平均粒徑為0.2mm至0.5mm,例如但不限於約0.25mm、0.30mm、0.35mm、0.4mm、0.45mm或0.5mm。於本揭露之又一具體實施例中,該顆粒結構之平均粒徑為0.3mm至0.5mm,較佳地,該顆粒結構之平均粒徑為0.4mm至0.5mm。於本揭露之至少一具體實施例中,該顆粒結構之粒徑為0.1mm至1.5mm,例如但不限於0.1mm、0.2mm、0.3mm、0.4mm、0.5mm、0.6mm、0.7mm、0.8mm、0.9mm、1.0mm、1.1mm、1.2mm、mm、1.3mm、1.4mm或1.5mm。 In one embodiment of the present disclosure, the particle structure helps preserve organic acids, and is therefore beneficial for promoting the absorption of organic acids. The particle structure comprises the following: a core, a seasoning shell layer, and a protective layer. Preferably, the average particle size is at least 0.2 mm. In another embodiment of the present disclosure, the average particle size of the particle structure is 0.2 mm to 0.5 mm, for example but not limited to about 0.25 mm, 0.30 mm, 0.35 mm, 0.4 mm, 0.45 mm, or 0.5 mm. In another embodiment of the present disclosure, the average particle size of the particle structure is 0.3 mm to 0.5 mm, preferably, the average particle size of the particle structure is 0.4 mm to 0.5 mm. In at least one specific embodiment of the present disclosure, the particle size of the particle structure is 0.1mm to 1.5mm, for example but not limited to 0.1mm, 0.2mm, 0.3mm, 0.4mm, 0.5mm, 0.6mm, 0.7mm, 0.8mm, 0.9mm, 1.0mm, 1.1mm, 1.2mm, mm, 1.3mm, 1.4mm or 1.5mm.
於本揭露之一具體實施例中,該顆粒結構之形狀係選自由圓球體、橢圓球體、立方體、圓柱體、長方體、四面體、椎體、星形、心形、扇形及貝殼形所組成群組之其中之一或其組合。 In a specific embodiment of the present disclosure, the shape of the particle structure is selected from one or a combination of the group consisting of sphere, ellipse, cube, cylinder, cuboid, tetrahedron, pyramid, star, heart, fan and shell.
於本揭露之一具體實施例中,該核心之粒徑或平均粒徑為0.01mm至0.3mm,例如但不限於0.02mm至0.1mm、0.02mm至0.15mm、0.06mm至0.08mm或0.1mm至0.3mm。 In one specific embodiment of the present disclosure, the particle size or average particle size of the core is 0.01mm to 0.3mm, for example but not limited to 0.02mm to 0.1mm, 0.02mm to 0.15mm, 0.06mm to 0.08mm or 0.1mm to 0.3mm.
於本揭露之一具體實施例中,該核心、調味殼層及保護層進一步包含食品上或生理上可接受之載劑或賦形劑。本揭露之食品上或生理上可接受之載劑或賦形劑包括但不限於澱粉(例如:米澱粉、小麥澱粉、玉米澱粉及小麥澱粉)、乳糖、蔗糖、葡萄糖、玉米甜味劑、糊精、環糊精、麥芽糖糊精、抗性澱粉、玉米來源可溶性纖維、菊苣纖維、寡糖、木質素、幾丁質、半纖維素、戊聚糖、β-葡聚糖、半乳甘露聚糖、甲殼素、樹膠、大豆膳食纖維、羧甲基澱粉鈉、丙酸羧基化澱粉、微晶纖維素、羧 甲基纖維素、羧甲基纖維素鈉、羥丙基甲基纖維素、甘露醇、山梨糖醇、硬脂酸鎂、磷酸二鈣、明膠、瓊脂、果膠、阿拉伯膠、海藻酸鈉、鹿角菜膠、刺槐豆膠、關華豆膠、塔拉膠、蒟蒻膠、黃耆膠、玉米糖膠、結蘭膠、卡德蘭膠、蟲膠、水或其中二者以上之組合。較佳地,該食品上或生理上可接受之載劑或賦形劑為澱粉、乳糖或其組合。較佳地,該食品上或生理上可接受之載劑或賦形劑為澱粉、寡糖、糊精、玉米來源可溶性纖維、菊苣纖維、果寡糖或其中兩者以上之組合。於本揭露之一具體實施例中,該保護層包含膠體,例如但不限於明膠、阿拉伯膠、海藻酸鈉、瓊脂、果膠、蟲膠、羧甲基纖維素、鹿角菜膠、玉米糖膠、褐藻酸鈉、結蘭膠、關華豆膠、塔拉膠或羥丙基甲基纖維素或其中兩者以上之組合。 In one embodiment of the present disclosure, the core, the seasoning shell layer and the protective layer further comprise a food or physiologically acceptable carrier or excipient. The food or physiologically acceptable carrier or excipient of the present disclosure includes but is not limited to starch (e.g., rice starch, wheat starch, corn starch and wheat starch), lactose, sucrose, glucose, corn sweetener, dextrin, cyclodextrin, maltodextrin, resistant starch, corn-derived soluble fiber, chicory fiber, oligosaccharides, lignin, chitin, hemicellulose, pentosan, β-glucan, galactomannan, chitosan, gum, soy Dietary fiber, sodium carboxymethyl starch, carboxylated starch propionate, microcrystalline cellulose, carboxymethyl cellulose, sodium carboxymethyl cellulose, hydroxypropyl methyl cellulose, mannitol, sorbitol, magnesium stearate, dicalcium phosphate, gelatin, agar, pectin, gum arabic, sodium alginate, carrageenan, locust bean gum, Guanhua bean gum, tara gum, konjac gum, astragalus gum, corn syrup, jelly gum, curdlan gum, worm gum, water or a combination of two or more thereof. Preferably, the food- or physiologically acceptable carrier or formulator is starch, lactose or a combination thereof. Preferably, the food- or physiologically acceptable carrier or excipient is starch, oligosaccharide, dextrin, corn-derived soluble fiber, chicory fiber, fructooligosaccharide, or a combination of two or more thereof. In a specific embodiment of the present disclosure, the protective layer comprises a colloid, such as but not limited to gelatin, gum arabic, sodium alginate, agar, pectin, wormwood, carboxymethyl cellulose, carrageenan, corn syrup, sodium alginate, gellan gum, guanyin, tara gum, or hydroxypropyl methyl cellulose, or a combination of two or more thereof.
本文中的術語「功能性成分」係指於食品中提供食用者超出基本營養價值且對健康有益處的成分,可增進食用者之身體健康及/或降低食用者罹患疾病之風險,例如:促進腸胃道健康、幫助消化、強健骨骼、保健牙齒、清新口氣、緩解壓力及緊張、改善或預防心血管疾病、糖尿病、肥胖症或骨質疏鬆症等。本揭露之功能性成分包括但不限於纖維、紅茶菌菇發酵液、益生質、益生菌、提升專注力之有效成分、膳食纖維、維生素、礦物質、類胡蘿蔔素、類黃酮、酶、抗氧化劑、植物雌激素、植物固醇、軟磷脂、脂肪酸、胺基酸、肌酸、蛋白質(例如大豆蛋白質或膠原蛋白)、咖啡因、胜肽、植物萃取物、菇菌類菌絲體、菇菌類子實體、蟲草類菌絲體、蟲草類子實體或其中二者以上之組合。於本揭露之一具體實施例中,該功能性成分係選自由紅茶菌菇發酵飲品製造過程中產生的有機酸包含但不限於醋酸。 The term "functional ingredient" in this article refers to ingredients in food that provide consumers with health benefits beyond basic nutritional value, which can improve the consumer's physical health and/or reduce the consumer's risk of disease, such as: promoting gastrointestinal health, aiding digestion, strengthening bones, protecting teeth, freshening breath, relieving stress and tension, improving or preventing cardiovascular disease, diabetes, obesity or osteoporosis, etc. The functional ingredients disclosed herein include but are not limited to fiber, fermented kombucha mushroom liquid, prebiotics, probiotics, active ingredients for improving concentration, dietary fiber, vitamins, minerals, carotenoids, flavonoids, enzymes, antioxidants, phytoestrogens, plant sterols, lecithin, fatty acids, amino acids, creatine, proteins (such as soy protein or collagen), caffeine, peptides, plant extracts, mushroom mycelium, mushroom fruiting bodies, cordyceps mycelium, cordyceps fruiting bodies, or a combination of two or more thereof. In a specific embodiment of the disclosure, the functional ingredient is selected from organic acids produced in the production process of kombucha mushroom fermented beverages, including but not limited to acetic acid.
本文中的術語「益生質」係指一種或多種食品成份,其可選擇性刺激益生菌在宿主消化道中的生長或活性,進而達到促進宿主健康之效果。於本揭露之一具體實施例中,該益生質係選自由醣類、糖醇及地靈粉末所組成群組之其中之一或其組合。較佳地,該醣類為寡醣或多醣。較佳地,該醣類係選自由木寡醣、大豆寡醣、膳食纖維、果寡醣(fructo-oligosaccharide,FOS)、異麥芽寡醣、乳果寡醣、乳酮糖、半乳寡醣(galacto-oligosaccharide,GOS)、棉子糖、菊苣纖維(菊糖)、聚糊精、聚葡萄糖、葡萄寡醣、甘露寡醣、阿拉伯寡醣、岩藻寡醣(fuco-oligosaccharide)、殼寡醣(chito-oligosaccharide)、乳糖醇及乳酮糖所組成群組之其中之一或其組合。於本揭露之一具體實施例中,該益生質係選自由膳食纖維、寡糖、低聚醣所組成群組之其中之一或其組合,較佳地,該寡糖為果寡糖、半乳寡糖、菊苣纖維或其中兩者以上之組合。 The term "prebiotic" herein refers to one or more food ingredients that can selectively stimulate the growth or activity of probiotics in the digestive tract of the host, thereby achieving the effect of promoting the health of the host. In a specific embodiment of the present disclosure, the prebiotic is selected from one or a combination of the group consisting of carbohydrates, sugar alcohols and dilinolenic acid powder. Preferably, the carbohydrate is an oligosaccharide or a polysaccharide. Preferably, the carbohydrate is selected from the group consisting of xylo-oligosaccharide, soybean oligosaccharide, dietary fiber, fructo-oligosaccharide (FOS), isomalto-oligosaccharide, lacto-oligosaccharide, lactulose, galacto-oligosaccharide (GOS), raffinose, chicory fiber (inulin), polydextrin, polydextrose, glucooligosaccharide, manno-oligosaccharide, arabino-oligosaccharide, fuco-oligosaccharide, chito-oligosaccharide, lactitol and lactulose, or a combination thereof. In a specific embodiment of the present disclosure, the prebiotic is selected from one of the groups consisting of dietary fiber, oligosaccharides, and oligosaccharides, or a combination thereof. Preferably, the oligosaccharide is fructooligosaccharide, galacto-oligosaccharide, chicory fiber, or a combination of two or more thereof.
本文中的術語「益生菌」係指有益於宿主健康且無致病性或低致病性的微生物。於本揭露之至少一具體實施例中,該益生菌係選自由芽孢乳酸菌(Bacillus coagulans)、比菲德氏菌(Bifidobacterium bifidum)、短雙歧桿菌(Bifidobacterium breve)、長雙歧桿菌(Bifidobacterium infants)、動物雙歧桿菌(Bifidobacterium lactis)、比菲德氏龍根菌(Bifidobacterium longum)、嗜酸乳桿菌(Lactobacillus acidophilus)、短乳桿菌(Lactobacillus brevis)、保加利亞乳桿菌(Lactobacillus bulgaricus)、乾酪乳桿菌(Lactobacillus casei)、酵素乳桿菌(Lactobacillus fermentum)、加氏乳桿菌(Lactobacillus gasseri)、瑞士乳桿菌(Lactobacillus helveticus)、約氏乳桿菌(Lactobacillus johnsonii)、副乾酪乳桿菌(Lactobacillus paracasei)、戊糖乳桿菌(Lactobacillus pentosus)、胚芽乳酸菌(Lactobacillus plantarum)、洛德乳桿菌(Lactobacillus reuteri)、鼠李糖乳桿菌(Lactobacillus rhamnosus)、唾液乳桿菌(Lactobacillus salivarius)、乳酸乳球菌(Lactococcus lactis)、嗜熱鏈球菌(Streptococcus thermophiles)、戊糖片球菌(Pediococcus pentosaceus)、乳酸片球菌(Pediococcus acidilactici)及青春雙歧桿菌(Bifidobacterium adolescentis)所組成群組之其中之一或其組合。較佳地,該益生菌係選自由動物雙歧桿菌(Bifidobacterium lactis)、酵素乳桿菌(Lactobacillus fermentum)、胚芽乳酸菌(Lactobacillus plantarum)及副乾酪乳桿菌(Lactobacillus paracasei)所組成群組之其中之一或其組合。 The term "probiotics" herein refers to microorganisms that are beneficial to the health of the host and are non-pathogenic or low-pathogenic. In at least one embodiment of the present disclosure, the probiotic is selected from the group consisting of Bacillus coagulans , Bifidobacterium bifidum , Bifidobacterium breve , Bifidobacterium infants , Bifidobacterium lactis , Bifidobacterium longum, Lactobacillus acidophilus , Lactobacillus brevis , Lactobacillus bulgaricus , Lactobacillus casei , Lactobacillus fermentum , Lactobacillus gasseri, Lactobacillus gasseri ), Lactobacillus helveticus , Lactobacillus johnsonii , Lactobacillus paracasei , Lactobacillus pentosus , Lactobacillus plantarum , Lactobacillus reuteri , Lactobacillus rhamnosus , Lactobacillus salivarius , Lactococcus lactis , Streptococcus thermophiles , Pediococcus pentosaceus , Pediococcus acidilactici ) and Bifidobacterium adolescentis or a combination thereof. Preferably, the probiotic is selected from the group consisting of Bifidobacterium lactis , Lactobacillus fermentum , Lactobacillus plantarum and Lactobacillus paracasei or a combination thereof.
於本揭露之至少一具體實施例中,該顆粒結構之紅茶粉係選自由錫蘭紅茶粉、伯爵紅茶粉、阿薩姆紅茶粉、大吉嶺紅茶粉所組成群組之其中之一或其組合。 In at least one specific embodiment of the present disclosure, the black tea powder in the particle structure is selected from one of the group consisting of Ceylon black tea powder, Earl Grey black tea powder, Assam black tea powder, and Darjeeling black tea powder, or a combination thereof.
於本揭露之至少一具體實施例中,該顆粒結構之纖維係選自由可溶性纖維、菊苣纖維、果寡糖所組成群組之其中之一或其組合。 In at least one specific embodiment of the present disclosure, the fiber of the particle structure is selected from one of the groups consisting of soluble fiber, chicory fiber, and fructooligosaccharide or a combination thereof.
於本揭露之至少一具體實施例中,該紅茶菌菇發酵液進一步包含有機酸或益生菌。於本揭露之一些具體實施例中,該紅茶菌菇發酵液之有機酸係選自由醋酸、檸檬酸、琥珀酸、草酸、葡萄糖醛酸及葡萄糖酸所組成群組之其中之一或其組合。於本揭露之一些具體實施例中,該益生菌為乳酸菌。 In at least one specific embodiment of the present disclosure, the fermented kombucha mushroom liquid further comprises an organic acid or a probiotic. In some specific embodiments of the present disclosure, the organic acid of the fermented kombucha mushroom liquid is selected from one or a combination of the group consisting of acetic acid, citric acid, succinic acid, oxalic acid, glucuronic acid and gluconic acid. In some specific embodiments of the present disclosure, the probiotic is a lactic acid bacterium.
本文中的術語「釋放」係指在特定外界環境下,例如但不限 於在液體中,本揭露之顆粒結構將其所包含之成分向外界遞送的特性。於本揭露之一具體實施例中,該保護層可以提升本揭露之顆粒結構之抗吸濕和保存性。於本揭露之一具體實施例中,該調味殼層具有釋放該功能性成分之作用,例如該保護層及調味殼層於液體中崩解、分解或溶解,以釋放該功能性成分。於本揭露之一具體實施例中,該液體為飲品,較佳為飲用水。 The term "release" herein refers to the property of the particle structure disclosed herein to deliver the components contained therein to the outside world in a specific external environment, such as but not limited to in a liquid. In one specific embodiment of the disclosure, the protective layer can enhance the moisture absorption resistance and preservation of the particle structure disclosed herein. In one specific embodiment of the disclosure, the flavoring shell layer has the function of releasing the functional component, for example, the protective layer and the flavoring shell layer disintegrate, decompose or dissolve in the liquid to release the functional component. In one specific embodiment of the disclosure, the liquid is a beverage, preferably drinking water.
本文中的術語「調味劑」係指食品上或生理上可接受之天然、合成或半合成物質,其在食用者體內誘發味覺、嗅覺、觸覺等感受,其中,在食用者體內誘發甜味感受者為「甜味劑」;在食用者體內誘發酸味感受者為「酸味劑」。本揭露之甜味劑包括但不限於天然植物來源所獲得之汁液、粉末、糖漿、萃取物、濃縮物或香料,該天然植物來源例如:巧克力、檸檬、草莓、香蕉、莓果、芒果、哈密瓜、百香果、鳳梨、水蜜桃、櫻桃、肉桂、蘋果、茴香、蜂蜜、梨、楓糖、葡萄、葡萄柚、柳橙、橘子、西瓜、羅漢果、蘑菇或香草;醣類甜味劑包括但不限於乳糖、半乳寡糖、蔗糖、果糖、麥芽糖、葡萄糖或砂糖;糖醇類甜味劑包括但不限於木糖醇、甘露糖醇、山梨糖醇、赤藻糖醇、異麥芽酮糖醇、甜菊糖苷、赤藻糖醇或乳糖醇;以及人工甜味劑包括但不限於阿斯巴甜或其衍生物、乙醯磺胺酸鉀、新橙皮苷二氫查耳酮、甘草素、醋磺內酯鉀或蔗糖素。於本揭露之一具體實施例中,該甜味劑為羅漢果萃取物、甜菊糖苷、蘑菇萃取物或其中兩者以上之組合。另一具體實施例中,該甜味劑為羅漢果萃取物、蔗糖素、醋磺內酯鉀、甜菊糖苷或兩者以上之組合。本揭露之酸味劑包括但不限於檸檬酸、檸檬酸鈉、檸檬酸三鈉、己二酸、丁二酸、丁二酸單鈉乳酸、乳酸 鈉、蘋果酸、蘋果酸鈉、磷酸、酒石酸、酒石酸鈉、葡萄糖酸、葡萄糖酸鉀、葡萄糖酸鈉、乙酸、冰乙酸或胺基乙酸。於本揭露之一具體實施例中,該保護層另包含甜味劑、酸味劑或其組合,較佳地,該甜味劑為天然植物來源所獲得之糖漿、萃取物、濃縮物或香料、糖醇類甜味劑或其組合;更佳地,該甜味劑為羅漢果萃取物、甜菊糖苷、蔗糖素、醋磺內酯鉀或其中兩者以上之組合。於本揭露之一具體實施例中,該保護層具有釋放該調味劑之作用,例如該保護層於液體中崩解、分解或溶解,以釋放該調味劑。於本揭露之一具體實施例中,該液體為飲用水。 The term "flavoring agent" herein refers to a natural, synthetic or semi-synthetic substance that is acceptable in food or physiologically, and which induces taste, smell, touch and other sensations in the body of the consumer. Among them, the one that induces sweetness in the body of the consumer is a "sweetener"; the one that induces sourness in the body of the consumer is a "sour agent". The sweeteners disclosed herein include but are not limited to juices, powders, syrups, extracts, concentrates or spices obtained from natural plant sources, such as chocolate, lemon, strawberry, banana, berry, mango, cantaloupe, passion fruit, pineapple, peach, cherry, cinnamon, apple, fennel, honey, pear, maple syrup, grape, grapefruit, orange, tangerine, watermelon, monk fruit, mushroom or vanilla; carbohydrate sweeteners The sweetener includes but is not limited to lactose, galacto-oligosaccharide, sucrose, fructose, maltose, glucose or granulated sugar; the sugar alcohol sweetener includes but is not limited to xylitol, mannitol, sorbitol, erythritol, isomalt, steviol glycoside, erythritol or lactitol; and the artificial sweetener includes but is not limited to aspartame or its derivatives, acesulfame potassium, neohesperidin dihydrochalcone, glycyrrhizin, acesulfame potassium or sucralose. In one embodiment of the present disclosure, the sweetener is a Luo Han Guo extract, steviol glycoside, mushroom extract or a combination of two or more thereof. In another embodiment, the sweetener is a Luo Han Guo extract, sucralose, acesulfame potassium, steviol glycoside or a combination of two or more thereof. The acidulants disclosed herein include but are not limited to citric acid, sodium citrate, trisodium citrate, adipic acid, succinic acid, monosodium succinate, lactic acid, sodium lactate, apple acid, sodium appleate, phosphoric acid, tartaric acid, sodium tartrate, gluconic acid, potassium gluconate, sodium gluconate, acetic acid, glacial acetic acid or aminoacetic acid. In a specific embodiment of the present disclosure, the protective layer further comprises a sweetener, an acidulant or a combination thereof. Preferably, the sweetener is a syrup, extract, concentrate or flavor obtained from a natural plant source, a sugar alcohol sweetener or a combination thereof; more preferably, the sweetener is a monk fruit extract, stevioside, sucralose, acesulfame potassium or a combination of two or more thereof. In one embodiment of the present disclosure, the protective layer has the function of releasing the flavoring agent, for example, the protective layer disintegrates, decomposes or dissolves in the liquid to release the flavoring agent. In one embodiment of the present disclosure, the liquid is drinking water.
於本揭露之一具體實施例中,該保護層無添加抗結塊劑。 In one specific embodiment of the present disclosure, the protective layer does not contain an anti-caking agent.
於本揭露之一具體實施例中,該保護層之厚度為0.01mm至0.02mm、0.03mm至0.05mm、或0.015mm至0.025mm。 In one specific embodiment of the present disclosure, the thickness of the protective layer is 0.01mm to 0.02mm, 0.03mm to 0.05mm, or 0.015mm to 0.025mm.
於本揭露之一具體實施例中,該顆粒結構包含65.5%至90.8%之功能性成分。較佳地,該顆粒結構包含10%至30%之含紅茶菌菇發酵液。於本揭露之一具體實施例中,該顆粒結構包含1%至10%之紅茶粉。較佳地,該顆粒結構包含50%至70%之纖維。更佳地,該顆粒結構包含20%至30%之紅茶菌菇發酵液、3%至8%之紅茶粉及60%至70%之纖維。 In one embodiment of the present disclosure, the particle structure contains 65.5% to 90.8% of functional ingredients. Preferably, the particle structure contains 10% to 30% of fermented tea containing tea. In one embodiment of the present disclosure, the particle structure contains 1% to 10% of black tea powder. Preferably, the particle structure contains 50% to 70% of fiber. More preferably, the particle structure contains 20% to 30% of fermented tea containing tea, 3% to 8% of black tea powder and 60% to 70% of fiber.
於本揭露之一具體實施例中,係使用流動床噴霧造粒製程將該功能性成分與該載劑或該賦形劑混合,以達到快速且均勻混合之目的。 In one specific embodiment of the present disclosure, the functional ingredient is mixed with the carrier or the excipient using a fluidized bed spray granulation process to achieve rapid and uniform mixing.
以下係藉由具體的製備例及實施例進一步說明本揭露之特點及其功效,但非用於限制本揭露之範圍。 The following is a detailed description of the features and effects of the present disclosure through specific preparation examples and implementation examples, but is not intended to limit the scope of the present disclosure.
製備例Preparation example
圖1顯示製備本揭露之顆粒結構的方法,其包含下列步驟: 步驟(a):將玉米來源可溶性纖維、即溶紅茶粉、菊苣纖維等功能性成分進行過篩;步驟(b):將過篩後之成分以流動床乾燥設備進行57℃至63℃混合及乾燥;步驟(c):將混合及乾燥後之成分進行噴霧造粒程序以形成核心,其過程中可視需要加入水、食用香料、甜味劑、酸味劑、膠體或其中兩者以上之組合;步驟(d):加入水、食用香料、甜味劑、酸味劑、膠體或其中兩者以上之組合,以形成包覆核心之調味殼層;步驟(e):依序添加紅茶菌發酵液成分、香氣之微膠囊及抗吸濕之膠體組合成分針對顆粒結構進行乾燥;步驟(f):針對顆粒結構進行整粒,以達到所需之平均粒徑及形狀。 FIG1 shows a method for preparing the granular structure disclosed herein, which comprises the following steps: Step (a): Screening the functional ingredients such as corn-derived soluble fiber, instant black tea powder, chicory fiber, etc.; Step (b): Mixing and drying the screened ingredients at 57°C to 63°C using a fluidized bed drying device; Step (c): Performing a spray granulation process on the mixed and dried ingredients to form a core, during which water, edible flavorings, Sweetener, acidulant, colloid or a combination of two or more thereof; Step (d): adding water, edible flavor, sweetener, acidulant, colloid or a combination of two or more thereof to form a seasoning shell layer covering the core; Step (e): sequentially adding kombucha fermentation liquid component, aroma microcapsule and anti-hygroscopic colloid component to dry the particle structure; Step (f): performing particle size adjustment on the particle structure to achieve the required average particle size and shape.
實施例1:顆粒結構之剖面Example 1: Cross-section of particle structure
如圖2所示,本揭露之顆粒結構100包含紅茶粉11、纖維12、紅茶菌菇發酵液13、調味殼層22及保護層23,其中,該調味殼層22包含香氣微膠囊21。
As shown in FIG. 2 , the
實施例2:噴霧造粒溫度對有機酸保留之影響Example 2: Effect of spray granulation temperature on organic acid retention
以上述製備例所述方法,於37℃至43℃、57℃至63℃、77℃至83℃之噴霧造粒溫度範圍下,分別製備顆粒結構之實例A及實例A’、實例B及實例B’、實例C,並於製備完成時及常溫儲藏1個月後測定每克實例中的醋酸含量(毫克),結果如下表1及表2所示:
上表1顯示於顆粒結構製備完成時,實例B之醋酸含量高於實例A及實例C。上表2則顯示經常溫儲藏1個月後,實例B’之醋酸耗損率低於實例A’。上述數據表示使用57℃至63℃之噴霧造粒溫度所形成的顆粒結構具有較佳的醋酸保留效果。 Table 1 above shows that when the granular structure is prepared, the acetic acid content of Example B is higher than that of Example A and Example C. Table 2 above shows that after being stored at room temperature for one month, the acetic acid consumption rate of Example B' is lower than that of Example A'. The above data indicate that the granular structure formed using a spray granulation temperature of 57°C to 63°C has a better acetic acid retention effect.
實施例3:流動性測試 Example 3: Fluidity test
測定實施例2中的實例B與市售品之總體密度(bulk density)及振實密度(tapped density),再進一步計算其卡爾指數(Carr’s index)及豪斯納比(Hausner ratio),結果如下表3所示:
總體密度係指未經振實之顆粒樣品的質量與其總體積(包括顆粒間的空隙體積)之比值,一般而言,其值越低的產品,其顆粒粒徑較大,相對利於包裝、運輸和儲存。振實密度則是指對裝有顆粒樣品的容器振動以使顆粒處於緊密填充狀態後的密度。卡爾指數及豪斯納比為流動性指標,其值越低,表示顆粒樣品之流動性越高。由上表可知,實例B之總體密度、卡爾指數及豪斯納比皆小於市售品,表示本揭露之成品相較於其它市售品具有較佳的流動性與充填適性,且更有利於包裝、運輸和儲存。 The overall density refers to the ratio of the mass of the uncompacted particle sample to its total volume (including the volume of the voids between the particles). Generally speaking, the lower the value, the larger the particle size of the product, which is relatively convenient for packaging, transportation and storage. The tapped density refers to the density after the container containing the particle sample is vibrated to make the particles in a densely packed state. The Karl index and Hausner ratio are flowability indicators. The lower the value, the higher the flowability of the particle sample. As can be seen from the above table, the overall density, Karl index and Hausner ratio of Example B are all lower than those of commercial products, indicating that the finished product disclosed herein has better flowability and filling suitability than other commercial products, and is more convenient for packaging, transportation and storage.
上述製備例或實施例僅為例示性說明,而非用於限制本揭露。本領域之通常知識者均可在不違背本揭露之精神及範疇下,對上述實施例進行修飾與改變。因此,本揭露之權利保護範圍係由所附之申請專利範圍所定義,只要不影響本揭露之效果及實施目的,應涵蓋於此公開技術內容中。 The above preparation examples or implementation examples are only illustrative and are not intended to limit the present disclosure. People with ordinary knowledge in this field can modify and change the above implementation examples without violating the spirit and scope of the present disclosure. Therefore, the scope of protection of the present disclosure is defined by the scope of the attached patent application. As long as it does not affect the effect and implementation purpose of the present disclosure, it should be included in the content of this public technology.
100:顆粒結構 100: Particle structure
11:紅茶粉 11: Black tea powder
12:纖維 12: Fiber
13:紅茶菌菇發酵液 13: Kombucha mushroom fermented liquid
21:香氣微膠囊 21: Aroma microcapsule
22:調味殼層 22: Seasoning the crust
23:保護層 23: Protective layer
Claims (8)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TW111150976A TWI868553B (en) | 2022-12-30 | 2022-12-30 | Granular structure with active compound of organic acids and method for preparing the same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TW111150976A TWI868553B (en) | 2022-12-30 | 2022-12-30 | Granular structure with active compound of organic acids and method for preparing the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TW202425955A TW202425955A (en) | 2024-07-01 |
| TWI868553B true TWI868553B (en) | 2025-01-01 |
Family
ID=92929084
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW111150976A TWI868553B (en) | 2022-12-30 | 2022-12-30 | Granular structure with active compound of organic acids and method for preparing the same |
Country Status (1)
| Country | Link |
|---|---|
| TW (1) | TWI868553B (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105747061B (en) * | 2016-02-29 | 2019-02-12 | 丽水学院 | A kind of method for preparing kombucha solid beverage |
| TWM605965U (en) * | 2020-06-17 | 2021-01-01 | 葡萄王生技股份有限公司 | Granular structure for encapsulating probiotics |
| TWM605957U (en) * | 2020-06-11 | 2021-01-01 | 葡萄王生技股份有限公司 | Calcium-containing granular structure |
-
2022
- 2022-12-30 TW TW111150976A patent/TWI868553B/en active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105747061B (en) * | 2016-02-29 | 2019-02-12 | 丽水学院 | A kind of method for preparing kombucha solid beverage |
| TWM605957U (en) * | 2020-06-11 | 2021-01-01 | 葡萄王生技股份有限公司 | Calcium-containing granular structure |
| TWM605965U (en) * | 2020-06-17 | 2021-01-01 | 葡萄王生技股份有限公司 | Granular structure for encapsulating probiotics |
Also Published As
| Publication number | Publication date |
|---|---|
| TW202425955A (en) | 2024-07-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Sarao et al. | Probiotics, prebiotics, and microencapsulation: A review | |
| CN101541194B (en) | Probiotic oral dosage forms | |
| US20120015075A1 (en) | Chewable supplement with live microorganisms | |
| CN114698849A (en) | A kind of probiotic composition and its preparation method and application | |
| JP2012175977A (en) | Composition for administering microorganism into intestine | |
| CN116634889A (en) | Improved protein digestion and amino acid bioavailability by probiotic strains | |
| CN103347398A (en) | Soluble milk-based tablet surface-treated with carbohydrate | |
| TWM605965U (en) | Granular structure for encapsulating probiotics | |
| CN107835641A (en) | Glyceryl rubber candy and foam confectionary products with probiotics | |
| JP6945888B1 (en) | Composition for improving immune function | |
| TWI868553B (en) | Granular structure with active compound of organic acids and method for preparing the same | |
| KR20250152039A (en) | Food composition with snow melt texture and preparing method thereof | |
| KR102535339B1 (en) | Glycerin-based and protein-based foamed candy products with probiotic bacteria | |
| TWM641394U (en) | Granular structure with active compound of organic acids | |
| CN103997900A (en) | Soluble non-dairy creamer tablet surface-treated with carbohydrate | |
| CN109259245A (en) | A kind of the probiotics Intestine-lubricatinhealth-care health-care food and preparation method stable by fiber | |
| Kandur et al. | Oral pharmabiotic tablet formulations | |
| JP2612001B2 (en) | Granules containing useful intestinal bacteria and method for producing the same | |
| CN105724571B (en) | Isotonic probiotics preparation and preparation method thereof | |
| JP7440144B1 (en) | Oral composition | |
| TWM602905U (en) | Probiotic particles with core-shell structure | |
| Şenöztop et al. | A comprehensive review on the development of probiotic supplemented confectioneries | |
| KR102907346B1 (en) | Food composition with snow melt texture | |
| CN118383445A (en) | Composition containing probiotics and probiotic tablet candy prepared by using same | |
| JP2020129986A (en) | Oral composition |