TWM641394U - Granular structure with active compound of organic acids - Google Patents
Granular structure with active compound of organic acids Download PDFInfo
- Publication number
- TWM641394U TWM641394U TW111214643U TW111214643U TWM641394U TW M641394 U TWM641394 U TW M641394U TW 111214643 U TW111214643 U TW 111214643U TW 111214643 U TW111214643 U TW 111214643U TW M641394 U TWM641394 U TW M641394U
- Authority
- TW
- Taiwan
- Prior art keywords
- granular structure
- acid
- fiber
- core
- shell
- Prior art date
Links
- 150000007524 organic acids Chemical class 0.000 title claims abstract description 29
- 235000005985 organic acids Nutrition 0.000 title claims abstract description 11
- 150000001875 compounds Chemical class 0.000 title description 2
- 239000004615 ingredient Substances 0.000 claims abstract description 36
- 239000000835 fiber Substances 0.000 claims abstract description 30
- 239000011241 protective layer Substances 0.000 claims abstract description 26
- 235000019226 kombucha tea Nutrition 0.000 claims abstract description 24
- 239000010410 layer Substances 0.000 claims abstract description 5
- 239000002245 particle Substances 0.000 claims description 30
- 239000000843 powder Substances 0.000 claims description 27
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 26
- 239000007788 liquid Substances 0.000 claims description 23
- 235000011194 food seasoning agent Nutrition 0.000 claims description 19
- 244000269722 Thea sinensis Species 0.000 claims description 14
- 235000006468 Thea sinensis Nutrition 0.000 claims description 14
- 235000020279 black tea Nutrition 0.000 claims description 14
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 12
- 239000006041 probiotic Substances 0.000 claims description 11
- 235000018291 probiotics Nutrition 0.000 claims description 11
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 claims description 9
- 235000007542 Cichorium intybus Nutrition 0.000 claims description 8
- RGHNJXZEOKUKBD-SQOUGZDYSA-N D-gluconic acid Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O RGHNJXZEOKUKBD-SQOUGZDYSA-N 0.000 claims description 8
- 239000003094 microcapsule Substances 0.000 claims description 8
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims description 6
- RGHNJXZEOKUKBD-UHFFFAOYSA-N D-gluconic acid Natural products OCC(O)C(O)C(O)C(O)C(O)=O RGHNJXZEOKUKBD-UHFFFAOYSA-N 0.000 claims description 4
- KDYFGRWQOYBRFD-UHFFFAOYSA-N Succinic acid Natural products OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 claims description 4
- KDYFGRWQOYBRFD-NUQCWPJISA-N butanedioic acid Chemical compound O[14C](=O)CC[14C](O)=O KDYFGRWQOYBRFD-NUQCWPJISA-N 0.000 claims description 4
- FTSSQIKWUOOEGC-RULYVFMPSA-N fructooligosaccharide Chemical compound OC[C@H]1O[C@@](CO)(OC[C@@]2(OC[C@@]3(OC[C@@]4(OC[C@@]5(OC[C@@]6(OC[C@@]7(OC[C@@]8(OC[C@@]9(OC[C@@]%10(OC[C@@]%11(O[C@H]%12O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%12O)O[C@H](CO)[C@@H](O)[C@@H]%11O)O[C@H](CO)[C@@H](O)[C@@H]%10O)O[C@H](CO)[C@@H](O)[C@@H]9O)O[C@H](CO)[C@@H](O)[C@@H]8O)O[C@H](CO)[C@@H](O)[C@@H]7O)O[C@H](CO)[C@@H](O)[C@@H]6O)O[C@H](CO)[C@@H](O)[C@@H]5O)O[C@H](CO)[C@@H](O)[C@@H]4O)O[C@H](CO)[C@@H](O)[C@@H]3O)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@@H](O)[C@@H]1O FTSSQIKWUOOEGC-RULYVFMPSA-N 0.000 claims description 4
- 229940107187 fructooligosaccharide Drugs 0.000 claims description 4
- 239000000174 gluconic acid Substances 0.000 claims description 4
- 235000012208 gluconic acid Nutrition 0.000 claims description 4
- 241000894006 Bacteria Species 0.000 claims description 3
- IAJILQKETJEXLJ-UHFFFAOYSA-N Galacturonsaeure Natural products O=CC(O)C(O)C(O)C(O)C(O)=O IAJILQKETJEXLJ-UHFFFAOYSA-N 0.000 claims description 3
- 229940097043 glucuronic acid Drugs 0.000 claims description 3
- 239000004310 lactic acid Substances 0.000 claims description 3
- 235000014655 lactic acid Nutrition 0.000 claims description 3
- 235000006408 oxalic acid Nutrition 0.000 claims description 3
- 241000723343 Cichorium Species 0.000 claims 1
- AEMOLEFTQBMNLQ-AQKNRBDQSA-N D-glucopyranuronic acid Chemical compound OC1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O AEMOLEFTQBMNLQ-AQKNRBDQSA-N 0.000 claims 1
- 230000000529 probiotic effect Effects 0.000 claims 1
- 239000007921 spray Substances 0.000 abstract description 13
- 235000001674 Agaricus brunnescens Nutrition 0.000 abstract description 11
- 239000003795 chemical substances by application Substances 0.000 abstract description 11
- 238000005469 granulation Methods 0.000 abstract description 11
- 230000003179 granulation Effects 0.000 abstract description 11
- 238000002156 mixing Methods 0.000 abstract description 9
- 238000004321 preservation Methods 0.000 abstract description 7
- 238000000855 fermentation Methods 0.000 abstract description 5
- 230000004151 fermentation Effects 0.000 abstract description 5
- 239000002994 raw material Substances 0.000 abstract description 4
- 239000011248 coating agent Substances 0.000 abstract description 2
- 238000000576 coating method Methods 0.000 abstract description 2
- 238000013268 sustained release Methods 0.000 abstract 2
- 239000012730 sustained-release form Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 description 16
- 229920001542 oligosaccharide Polymers 0.000 description 15
- 235000003599 food sweetener Nutrition 0.000 description 13
- 239000003765 sweetening agent Substances 0.000 description 13
- 150000002482 oligosaccharides Chemical class 0.000 description 10
- 239000000546 pharmaceutical excipient Substances 0.000 description 10
- 230000000694 effects Effects 0.000 description 9
- 230000036541 health Effects 0.000 description 9
- 229960000583 acetic acid Drugs 0.000 description 8
- 235000013305 food Nutrition 0.000 description 8
- 229940093915 gynecological organic acid Drugs 0.000 description 8
- 230000008569 process Effects 0.000 description 8
- 244000298479 Cichorium intybus Species 0.000 description 7
- 229920002472 Starch Polymers 0.000 description 7
- 238000010521 absorption reaction Methods 0.000 description 7
- 239000000796 flavoring agent Substances 0.000 description 7
- 238000002360 preparation method Methods 0.000 description 7
- -1 rice starch Polymers 0.000 description 7
- 238000003860 storage Methods 0.000 description 7
- 239000000969 carrier Substances 0.000 description 6
- 239000000284 extract Substances 0.000 description 6
- 235000013355 food flavoring agent Nutrition 0.000 description 6
- 230000009286 beneficial effect Effects 0.000 description 5
- 235000013361 beverage Nutrition 0.000 description 5
- 239000008187 granular material Substances 0.000 description 5
- 239000000203 mixture Substances 0.000 description 5
- 235000019698 starch Nutrition 0.000 description 5
- 239000008107 starch Substances 0.000 description 5
- WBZFUFAFFUEMEI-UHFFFAOYSA-M Acesulfame k Chemical compound [K+].CC1=CC(=O)[N-]S(=O)(=O)O1 WBZFUFAFFUEMEI-UHFFFAOYSA-M 0.000 description 4
- 239000001692 EU approved anti-caking agent Substances 0.000 description 4
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical class OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 4
- 239000004383 Steviol glycoside Substances 0.000 description 4
- 240000008042 Zea mays Species 0.000 description 4
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 4
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 4
- 235000010358 acesulfame potassium Nutrition 0.000 description 4
- 229960004998 acesulfame potassium Drugs 0.000 description 4
- 239000000619 acesulfame-K Substances 0.000 description 4
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 4
- 239000000084 colloidal system Substances 0.000 description 4
- 235000005822 corn Nutrition 0.000 description 4
- 235000013325 dietary fiber Nutrition 0.000 description 4
- 235000013406 prebiotics Nutrition 0.000 description 4
- 235000019411 steviol glycoside Nutrition 0.000 description 4
- 229930182488 steviol glycoside Natural products 0.000 description 4
- 150000008144 steviol glycosides Chemical class 0.000 description 4
- 235000019202 steviosides Nutrition 0.000 description 4
- 235000000346 sugar Nutrition 0.000 description 4
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 description 3
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 3
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 3
- 239000004376 Sucralose Substances 0.000 description 3
- 239000004480 active ingredient Substances 0.000 description 3
- 239000013543 active substance Substances 0.000 description 3
- 239000001768 carboxy methyl cellulose Substances 0.000 description 3
- 239000012141 concentrate Substances 0.000 description 3
- 235000008504 concentrate Nutrition 0.000 description 3
- 239000003651 drinking water Substances 0.000 description 3
- 235000020188 drinking water Nutrition 0.000 description 3
- 238000009472 formulation Methods 0.000 description 3
- 235000021255 galacto-oligosaccharides Nutrition 0.000 description 3
- 150000003271 galactooligosaccharides Chemical class 0.000 description 3
- 239000008103 glucose Substances 0.000 description 3
- 239000008101 lactose Substances 0.000 description 3
- 229960000511 lactulose Drugs 0.000 description 3
- PFCRQPBOOFTZGQ-UHFFFAOYSA-N lactulose keto form Natural products OCC(=O)C(O)C(C(O)CO)OC1OC(CO)C(O)C(O)C1O PFCRQPBOOFTZGQ-UHFFFAOYSA-N 0.000 description 3
- 235000010413 sodium alginate Nutrition 0.000 description 3
- 239000000661 sodium alginate Substances 0.000 description 3
- 229940005550 sodium alginate Drugs 0.000 description 3
- 235000019408 sucralose Nutrition 0.000 description 3
- BAQAVOSOZGMPRM-QBMZZYIRSA-N sucralose Chemical compound O[C@@H]1[C@@H](O)[C@@H](Cl)[C@@H](CO)O[C@@H]1O[C@@]1(CCl)[C@@H](O)[C@H](O)[C@@H](CCl)O1 BAQAVOSOZGMPRM-QBMZZYIRSA-N 0.000 description 3
- 150000005846 sugar alcohols Chemical class 0.000 description 3
- 239000006188 syrup Substances 0.000 description 3
- 235000020357 syrup Nutrition 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 244000215068 Acacia senegal Species 0.000 description 2
- 229920001817 Agar Polymers 0.000 description 2
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 2
- 241000901050 Bifidobacterium animalis subsp. lactis Species 0.000 description 2
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 2
- 229920002101 Chitin Polymers 0.000 description 2
- 241000190633 Cordyceps Species 0.000 description 2
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 2
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- 239000004386 Erythritol Substances 0.000 description 2
- UNXHWFMMPAWVPI-UHFFFAOYSA-N Erythritol Natural products OCC(O)C(O)CO UNXHWFMMPAWVPI-UHFFFAOYSA-N 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 108010010803 Gelatin Proteins 0.000 description 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 description 2
- 235000010469 Glycine max Nutrition 0.000 description 2
- 244000068988 Glycine max Species 0.000 description 2
- 229920000084 Gum arabic Polymers 0.000 description 2
- 241000186840 Lactobacillus fermentum Species 0.000 description 2
- 241000186605 Lactobacillus paracasei Species 0.000 description 2
- 240000006024 Lactobacillus plantarum Species 0.000 description 2
- 235000013965 Lactobacillus plantarum Nutrition 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 2
- DLRVVLDZNNYCBX-UHFFFAOYSA-N Polydextrose Polymers OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(O)O1 DLRVVLDZNNYCBX-UHFFFAOYSA-N 0.000 description 2
- 229920001800 Shellac Polymers 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 229930006000 Sucrose Natural products 0.000 description 2
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 2
- 235000010489 acacia gum Nutrition 0.000 description 2
- 239000000205 acacia gum Substances 0.000 description 2
- WNLRTRBMVRJNCN-UHFFFAOYSA-N adipic acid Chemical compound OC(=O)CCCCC(O)=O WNLRTRBMVRJNCN-UHFFFAOYSA-N 0.000 description 2
- 239000008272 agar Substances 0.000 description 2
- 235000010419 agar Nutrition 0.000 description 2
- IAJILQKETJEXLJ-QTBDOELSSA-N aldehydo-D-glucuronic acid Chemical compound O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)C(O)=O IAJILQKETJEXLJ-QTBDOELSSA-N 0.000 description 2
- 229940009289 bifidobacterium lactis Drugs 0.000 description 2
- RYYVLZVUVIJVGH-UHFFFAOYSA-N caffeine Chemical compound CN1C(=O)N(C)C(=O)C2=C1N=CN2C RYYVLZVUVIJVGH-UHFFFAOYSA-N 0.000 description 2
- 150000001720 carbohydrates Chemical class 0.000 description 2
- 235000014633 carbohydrates Nutrition 0.000 description 2
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 2
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 2
- 235000010418 carrageenan Nutrition 0.000 description 2
- 229920001525 carrageenan Polymers 0.000 description 2
- 239000000679 carrageenan Substances 0.000 description 2
- 229940113118 carrageenan Drugs 0.000 description 2
- CVSVTCORWBXHQV-UHFFFAOYSA-N creatine Chemical compound NC(=[NH2+])N(C)CC([O-])=O CVSVTCORWBXHQV-UHFFFAOYSA-N 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 235000019414 erythritol Nutrition 0.000 description 2
- 229940009714 erythritol Drugs 0.000 description 2
- UNXHWFMMPAWVPI-ZXZARUISSA-N erythritol Chemical compound OC[C@H](O)[C@H](O)CO UNXHWFMMPAWVPI-ZXZARUISSA-N 0.000 description 2
- 235000019441 ethanol Nutrition 0.000 description 2
- 235000019985 fermented beverage Nutrition 0.000 description 2
- 235000019634 flavors Nutrition 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 239000008273 gelatin Substances 0.000 description 2
- 229920000159 gelatin Polymers 0.000 description 2
- 235000019322 gelatine Nutrition 0.000 description 2
- 235000011852 gelatine desserts Nutrition 0.000 description 2
- 230000007407 health benefit Effects 0.000 description 2
- 230000007366 host health Effects 0.000 description 2
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 description 2
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 description 2
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 description 2
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 description 2
- 235000020344 instant tea Nutrition 0.000 description 2
- 239000000832 lactitol Substances 0.000 description 2
- 235000010448 lactitol Nutrition 0.000 description 2
- VQHSOMBJVWLPSR-JVCRWLNRSA-N lactitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-JVCRWLNRSA-N 0.000 description 2
- 229960003451 lactitol Drugs 0.000 description 2
- 229940012969 lactobacillus fermentum Drugs 0.000 description 2
- 229940072205 lactobacillus plantarum Drugs 0.000 description 2
- JCQLYHFGKNRPGE-FCVZTGTOSA-N lactulose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 JCQLYHFGKNRPGE-FCVZTGTOSA-N 0.000 description 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 2
- 230000014759 maintenance of location Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 235000013336 milk Nutrition 0.000 description 2
- 239000008267 milk Substances 0.000 description 2
- 210000004080 milk Anatomy 0.000 description 2
- 238000004806 packaging method and process Methods 0.000 description 2
- 239000001814 pectin Substances 0.000 description 2
- 235000010987 pectin Nutrition 0.000 description 2
- 229920001277 pectin Polymers 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 239000004208 shellac Substances 0.000 description 2
- 235000013874 shellac Nutrition 0.000 description 2
- 229940113147 shellac Drugs 0.000 description 2
- ZLGIYFNHBLSMPS-ATJNOEHPSA-N shellac Chemical compound OCCCCCC(O)C(O)CCCCCCCC(O)=O.C1C23[C@H](C(O)=O)CCC2[C@](C)(CO)[C@@H]1C(C(O)=O)=C[C@@H]3O ZLGIYFNHBLSMPS-ATJNOEHPSA-N 0.000 description 2
- 238000007873 sieving Methods 0.000 description 2
- 239000001509 sodium citrate Substances 0.000 description 2
- 235000010356 sorbitol Nutrition 0.000 description 2
- 239000000600 sorbitol Substances 0.000 description 2
- 239000005720 sucrose Substances 0.000 description 2
- 229940100445 wheat starch Drugs 0.000 description 2
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 description 2
- OMDQUFIYNPYJFM-XKDAHURESA-N (2r,3r,4s,5r,6s)-2-(hydroxymethyl)-6-[[(2r,3s,4r,5s,6r)-4,5,6-trihydroxy-3-[(2s,3s,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]methoxy]oxane-3,4,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O[C@H]2[C@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)[C@H](O)[C@H](O)[C@H](O)O1 OMDQUFIYNPYJFM-XKDAHURESA-N 0.000 description 1
- FYGDTMLNYKFZSV-URKRLVJHSA-N (2s,3r,4s,5s,6r)-2-[(2r,4r,5r,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,4r,5r,6s)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1[C@@H](CO)O[C@@H](OC2[C@H](O[C@H](O)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O FYGDTMLNYKFZSV-URKRLVJHSA-N 0.000 description 1
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 description 1
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 1
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 description 1
- AEQDJSLRWYMAQI-UHFFFAOYSA-N 2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline Chemical compound C1CN2CC(C(=C(OC)C=C3)OC)=C3CC2C2=C1C=C(OC)C(OC)=C2 AEQDJSLRWYMAQI-UHFFFAOYSA-N 0.000 description 1
- GHQFLMULNSGOAR-UHFFFAOYSA-N 2,3-dihydroxybutanedioic acid;sodium Chemical compound [Na].OC(=O)C(O)C(O)C(O)=O GHQFLMULNSGOAR-UHFFFAOYSA-N 0.000 description 1
- CYDQOEWLBCCFJZ-UHFFFAOYSA-N 4-(4-fluorophenyl)oxane-4-carboxylic acid Chemical compound C=1C=C(F)C=CC=1C1(C(=O)O)CCOCC1 CYDQOEWLBCCFJZ-UHFFFAOYSA-N 0.000 description 1
- PVXPPJIGRGXGCY-TZLCEDOOSA-N 6-O-alpha-D-glucopyranosyl-D-fructofuranose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O)[C@H](O)C(O)(CO)O1 PVXPPJIGRGXGCY-TZLCEDOOSA-N 0.000 description 1
- 241000208140 Acer Species 0.000 description 1
- 244000144730 Amygdalus persica Species 0.000 description 1
- 244000099147 Ananas comosus Species 0.000 description 1
- 235000007119 Ananas comosus Nutrition 0.000 description 1
- 108010011485 Aspartame Proteins 0.000 description 1
- 241000193749 Bacillus coagulans Species 0.000 description 1
- 229920002498 Beta-glucan Polymers 0.000 description 1
- 241000186000 Bifidobacterium Species 0.000 description 1
- 241000186018 Bifidobacterium adolescentis Species 0.000 description 1
- 241000186016 Bifidobacterium bifidum Species 0.000 description 1
- 241000186012 Bifidobacterium breve Species 0.000 description 1
- 241001608472 Bifidobacterium longum Species 0.000 description 1
- 241000167854 Bourreria succulenta Species 0.000 description 1
- 235000004936 Bromus mango Nutrition 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 244000223760 Cinnamomum zeylanicum Species 0.000 description 1
- 244000241235 Citrullus lanatus Species 0.000 description 1
- 235000012828 Citrullus lanatus var citroides Nutrition 0.000 description 1
- 235000005979 Citrus limon Nutrition 0.000 description 1
- 244000131522 Citrus pyriformis Species 0.000 description 1
- 241000675108 Citrus tangerina Species 0.000 description 1
- 240000000560 Citrus x paradisi Species 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- 229920002261 Corn starch Polymers 0.000 description 1
- 244000241257 Cucumis melo Species 0.000 description 1
- 235000009847 Cucumis melo var cantalupensis Nutrition 0.000 description 1
- 229920000858 Cyclodextrin Polymers 0.000 description 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 1
- 229920001353 Dextrin Polymers 0.000 description 1
- 239000004375 Dextrin Substances 0.000 description 1
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 description 1
- 235000019739 Dicalciumphosphate Nutrition 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 239000001329 FEMA 3811 Substances 0.000 description 1
- 240000006927 Foeniculum vulgare Species 0.000 description 1
- 235000004204 Foeniculum vulgare Nutrition 0.000 description 1
- 235000016623 Fragaria vesca Nutrition 0.000 description 1
- 240000009088 Fragaria x ananassa Species 0.000 description 1
- 235000011363 Fragaria x ananassa Nutrition 0.000 description 1
- 235000002917 Fraxinus ornus Nutrition 0.000 description 1
- 244000182067 Fraxinus ornus Species 0.000 description 1
- 229930091371 Fructose Natural products 0.000 description 1
- 239000005715 Fructose Substances 0.000 description 1
- 229920000926 Galactomannan Polymers 0.000 description 1
- 229920002148 Gellan gum Polymers 0.000 description 1
- 239000004471 Glycine Substances 0.000 description 1
- 229920002488 Hemicellulose Polymers 0.000 description 1
- 229920001202 Inulin Polymers 0.000 description 1
- LPHGQDQBBGAPDZ-UHFFFAOYSA-N Isocaffeine Natural products CN1C(=O)N(C)C(=O)C2=C1N(C)C=N2 LPHGQDQBBGAPDZ-UHFFFAOYSA-N 0.000 description 1
- 229920002752 Konjac Polymers 0.000 description 1
- 240000001046 Lactobacillus acidophilus Species 0.000 description 1
- 235000013956 Lactobacillus acidophilus Nutrition 0.000 description 1
- 240000001929 Lactobacillus brevis Species 0.000 description 1
- 235000013957 Lactobacillus brevis Nutrition 0.000 description 1
- 244000199885 Lactobacillus bulgaricus Species 0.000 description 1
- 235000013960 Lactobacillus bulgaricus Nutrition 0.000 description 1
- 244000199866 Lactobacillus casei Species 0.000 description 1
- 235000013958 Lactobacillus casei Nutrition 0.000 description 1
- 241000186606 Lactobacillus gasseri Species 0.000 description 1
- 240000002605 Lactobacillus helveticus Species 0.000 description 1
- 235000013967 Lactobacillus helveticus Nutrition 0.000 description 1
- 241001468157 Lactobacillus johnsonii Species 0.000 description 1
- 241000186684 Lactobacillus pentosus Species 0.000 description 1
- 241000186604 Lactobacillus reuteri Species 0.000 description 1
- 241000218588 Lactobacillus rhamnosus Species 0.000 description 1
- 241000186869 Lactobacillus salivarius Species 0.000 description 1
- FURUXTVZLHCCNA-UHFFFAOYSA-N Liquiritigenin Natural products C1=CC(O)=CC=C1C1OC2=CC(O)=CC=C2C(=O)C1 FURUXTVZLHCCNA-UHFFFAOYSA-N 0.000 description 1
- 229920000161 Locust bean gum Polymers 0.000 description 1
- 229920002774 Maltodextrin Polymers 0.000 description 1
- 239000005913 Maltodextrin Substances 0.000 description 1
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 description 1
- 241000220225 Malus Species 0.000 description 1
- 235000011430 Malus pumila Nutrition 0.000 description 1
- 235000015103 Malus silvestris Nutrition 0.000 description 1
- 235000014826 Mangifera indica Nutrition 0.000 description 1
- 240000007228 Mangifera indica Species 0.000 description 1
- 229930195725 Mannitol Natural products 0.000 description 1
- 229920000168 Microcrystalline cellulose Polymers 0.000 description 1
- 240000005561 Musa balbisiana Species 0.000 description 1
- 235000018290 Musa x paradisiaca Nutrition 0.000 description 1
- 208000008589 Obesity Diseases 0.000 description 1
- 208000001132 Osteoporosis Diseases 0.000 description 1
- 235000000370 Passiflora edulis Nutrition 0.000 description 1
- 244000288157 Passiflora edulis Species 0.000 description 1
- 241000191998 Pediococcus acidilactici Species 0.000 description 1
- 241000191996 Pediococcus pentosaceus Species 0.000 description 1
- 235000010627 Phaseolus vulgaris Nutrition 0.000 description 1
- 244000046052 Phaseolus vulgaris Species 0.000 description 1
- 229920001100 Polydextrose Polymers 0.000 description 1
- HLCFGWHYROZGBI-JJKGCWMISA-M Potassium gluconate Chemical compound [K+].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O HLCFGWHYROZGBI-JJKGCWMISA-M 0.000 description 1
- XBDQKXXYIPTUBI-UHFFFAOYSA-M Propionate Chemical compound CCC([O-])=O XBDQKXXYIPTUBI-UHFFFAOYSA-M 0.000 description 1
- 235000006040 Prunus persica var persica Nutrition 0.000 description 1
- 235000014443 Pyrus communis Nutrition 0.000 description 1
- MUPFEKGTMRGPLJ-RMMQSMQOSA-N Raffinose Natural products O(C[C@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@@H](O[C@@]2(CO)[C@H](O)[C@@H](O)[C@@H](CO)O2)O1)[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 MUPFEKGTMRGPLJ-RMMQSMQOSA-N 0.000 description 1
- 229920000294 Resistant starch Polymers 0.000 description 1
- 241001409321 Siraitia grosvenorii Species 0.000 description 1
- 108010073771 Soybean Proteins Proteins 0.000 description 1
- 235000009184 Spondias indica Nutrition 0.000 description 1
- 241000194017 Streptococcus Species 0.000 description 1
- 244000057717 Streptococcus lactis Species 0.000 description 1
- 235000014897 Streptococcus lactis Nutrition 0.000 description 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 1
- 244000299461 Theobroma cacao Species 0.000 description 1
- 229920001615 Tragacanth Polymers 0.000 description 1
- MUPFEKGTMRGPLJ-UHFFFAOYSA-N UNPD196149 Natural products OC1C(O)C(CO)OC1(CO)OC1C(O)C(O)C(O)C(COC2C(C(O)C(O)C(CO)O2)O)O1 MUPFEKGTMRGPLJ-UHFFFAOYSA-N 0.000 description 1
- 235000009499 Vanilla fragrans Nutrition 0.000 description 1
- 244000263375 Vanilla tahitensis Species 0.000 description 1
- 235000012036 Vanilla tahitensis Nutrition 0.000 description 1
- 235000009754 Vitis X bourquina Nutrition 0.000 description 1
- 235000012333 Vitis X labruscana Nutrition 0.000 description 1
- 240000006365 Vitis vinifera Species 0.000 description 1
- 235000014787 Vitis vinifera Nutrition 0.000 description 1
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 description 1
- GZFRKSMKEAHRHR-UHFFFAOYSA-M [Na+].CC(O)C(O)=O.OC(=O)CCC([O-])=O Chemical compound [Na+].CC(O)C(O)=O.OC(=O)CCC([O-])=O GZFRKSMKEAHRHR-UHFFFAOYSA-M 0.000 description 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 1
- 239000001361 adipic acid Substances 0.000 description 1
- 235000011037 adipic acid Nutrition 0.000 description 1
- 229940023476 agar Drugs 0.000 description 1
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 description 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 1
- 235000001014 amino acid Nutrition 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 239000008122 artificial sweetener Substances 0.000 description 1
- 235000021311 artificial sweeteners Nutrition 0.000 description 1
- 239000000605 aspartame Substances 0.000 description 1
- 235000010357 aspartame Nutrition 0.000 description 1
- IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 description 1
- 229960003438 aspartame Drugs 0.000 description 1
- 239000000305 astragalus gummifer gum Substances 0.000 description 1
- 229940054340 bacillus coagulans Drugs 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 235000021028 berry Nutrition 0.000 description 1
- GUBGYTABKSRVRQ-QUYVBRFLSA-N beta-maltose Chemical compound OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O GUBGYTABKSRVRQ-QUYVBRFLSA-N 0.000 description 1
- 229940002008 bifidobacterium bifidum Drugs 0.000 description 1
- 229940009291 bifidobacterium longum Drugs 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 229960001948 caffeine Drugs 0.000 description 1
- VJEONQKOZGKCAK-UHFFFAOYSA-N caffeine Natural products CN1C(=O)N(C)C(=O)C2=C1C=CN2C VJEONQKOZGKCAK-UHFFFAOYSA-N 0.000 description 1
- 239000001506 calcium phosphate Substances 0.000 description 1
- 229940105329 carboxymethylcellulose Drugs 0.000 description 1
- 235000021466 carotenoid Nutrition 0.000 description 1
- 150000001747 carotenoids Chemical class 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 235000013351 cheese Nutrition 0.000 description 1
- 235000019693 cherries Nutrition 0.000 description 1
- 235000019219 chocolate Nutrition 0.000 description 1
- 235000017803 cinnamon Nutrition 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 239000008120 corn starch Substances 0.000 description 1
- 229940099112 cornstarch Drugs 0.000 description 1
- 229960003624 creatine Drugs 0.000 description 1
- 239000006046 creatine Substances 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 235000019425 dextrin Nutrition 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- NEFBYIFKOOEVPA-UHFFFAOYSA-K dicalcium phosphate Chemical compound [Ca+2].[Ca+2].[O-]P([O-])([O-])=O NEFBYIFKOOEVPA-UHFFFAOYSA-K 0.000 description 1
- 229940038472 dicalcium phosphate Drugs 0.000 description 1
- 229910000390 dicalcium phosphate Inorganic materials 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- WPUMTJGUQUYPIV-JIZZDEOASA-L disodium (S)-malate Chemical compound [Na+].[Na+].[O-]C(=O)[C@@H](O)CC([O-])=O WPUMTJGUQUYPIV-JIZZDEOASA-L 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 229930003935 flavonoid Natural products 0.000 description 1
- 235000017173 flavonoids Nutrition 0.000 description 1
- 150000002215 flavonoids Chemical class 0.000 description 1
- 235000012041 food component Nutrition 0.000 description 1
- 239000005417 food ingredient Substances 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 235000010492 gellan gum Nutrition 0.000 description 1
- 239000000216 gellan gum Substances 0.000 description 1
- 239000012362 glacial acetic acid Substances 0.000 description 1
- 229950006191 gluconic acid Drugs 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 235000021552 granulated sugar Nutrition 0.000 description 1
- 235000012907 honey Nutrition 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 229940029339 inulin Drugs 0.000 description 1
- JYJIGFIDKWBXDU-MNNPPOADSA-N inulin Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)OC[C@]1(OC[C@]2(OC[C@]3(OC[C@]4(OC[C@]5(OC[C@]6(OC[C@]7(OC[C@]8(OC[C@]9(OC[C@]%10(OC[C@]%11(OC[C@]%12(OC[C@]%13(OC[C@]%14(OC[C@]%15(OC[C@]%16(OC[C@]%17(OC[C@]%18(OC[C@]%19(OC[C@]%20(OC[C@]%21(OC[C@]%22(OC[C@]%23(OC[C@]%24(OC[C@]%25(OC[C@]%26(OC[C@]%27(OC[C@]%28(OC[C@]%29(OC[C@]%30(OC[C@]%31(OC[C@]%32(OC[C@]%33(OC[C@]%34(OC[C@]%35(OC[C@]%36(O[C@@H]%37[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O%37)O)[C@H]([C@H](O)[C@@H](CO)O%36)O)[C@H]([C@H](O)[C@@H](CO)O%35)O)[C@H]([C@H](O)[C@@H](CO)O%34)O)[C@H]([C@H](O)[C@@H](CO)O%33)O)[C@H]([C@H](O)[C@@H](CO)O%32)O)[C@H]([C@H](O)[C@@H](CO)O%31)O)[C@H]([C@H](O)[C@@H](CO)O%30)O)[C@H]([C@H](O)[C@@H](CO)O%29)O)[C@H]([C@H](O)[C@@H](CO)O%28)O)[C@H]([C@H](O)[C@@H](CO)O%27)O)[C@H]([C@H](O)[C@@H](CO)O%26)O)[C@H]([C@H](O)[C@@H](CO)O%25)O)[C@H]([C@H](O)[C@@H](CO)O%24)O)[C@H]([C@H](O)[C@@H](CO)O%23)O)[C@H]([C@H](O)[C@@H](CO)O%22)O)[C@H]([C@H](O)[C@@H](CO)O%21)O)[C@H]([C@H](O)[C@@H](CO)O%20)O)[C@H]([C@H](O)[C@@H](CO)O%19)O)[C@H]([C@H](O)[C@@H](CO)O%18)O)[C@H]([C@H](O)[C@@H](CO)O%17)O)[C@H]([C@H](O)[C@@H](CO)O%16)O)[C@H]([C@H](O)[C@@H](CO)O%15)O)[C@H]([C@H](O)[C@@H](CO)O%14)O)[C@H]([C@H](O)[C@@H](CO)O%13)O)[C@H]([C@H](O)[C@@H](CO)O%12)O)[C@H]([C@H](O)[C@@H](CO)O%11)O)[C@H]([C@H](O)[C@@H](CO)O%10)O)[C@H]([C@H](O)[C@@H](CO)O9)O)[C@H]([C@H](O)[C@@H](CO)O8)O)[C@H]([C@H](O)[C@@H](CO)O7)O)[C@H]([C@H](O)[C@@H](CO)O6)O)[C@H]([C@H](O)[C@@H](CO)O5)O)[C@H]([C@H](O)[C@@H](CO)O4)O)[C@H]([C@H](O)[C@@H](CO)O3)O)[C@H]([C@H](O)[C@@H](CO)O2)O)[C@@H](O)[C@H](O)[C@@H](CO)O1 JYJIGFIDKWBXDU-MNNPPOADSA-N 0.000 description 1
- JBQATDIMBVLPRB-UHFFFAOYSA-N isoliquiritigenin Natural products OC1=CC(O)=CC=C1C1OC2=CC(O)=CC=C2C(=O)C1 JBQATDIMBVLPRB-UHFFFAOYSA-N 0.000 description 1
- 239000000252 konjac Substances 0.000 description 1
- 235000019823 konjac gum Nutrition 0.000 description 1
- 229940039695 lactobacillus acidophilus Drugs 0.000 description 1
- 229940004208 lactobacillus bulgaricus Drugs 0.000 description 1
- 229940017800 lactobacillus casei Drugs 0.000 description 1
- 229940054346 lactobacillus helveticus Drugs 0.000 description 1
- 229940001882 lactobacillus reuteri Drugs 0.000 description 1
- 235000010445 lecithin Nutrition 0.000 description 1
- 239000000787 lecithin Substances 0.000 description 1
- 229940067606 lecithin Drugs 0.000 description 1
- 229920005610 lignin Polymers 0.000 description 1
- FURUXTVZLHCCNA-AWEZNQCLSA-N liquiritigenin Chemical compound C1=CC(O)=CC=C1[C@H]1OC2=CC(O)=CC=C2C(=O)C1 FURUXTVZLHCCNA-AWEZNQCLSA-N 0.000 description 1
- 235000010420 locust bean gum Nutrition 0.000 description 1
- 239000000711 locust bean gum Substances 0.000 description 1
- 235000019359 magnesium stearate Nutrition 0.000 description 1
- 239000001630 malic acid Substances 0.000 description 1
- 235000011090 malic acid Nutrition 0.000 description 1
- 229940035034 maltodextrin Drugs 0.000 description 1
- 150000003272 mannan oligosaccharides Chemical class 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 229960001855 mannitol Drugs 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 239000008108 microcrystalline cellulose Substances 0.000 description 1
- 235000019813 microcrystalline cellulose Nutrition 0.000 description 1
- 229940016286 microcrystalline cellulose Drugs 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- ITVGXXMINPYUHD-CUVHLRMHSA-N neohesperidin dihydrochalcone Chemical compound C1=C(O)C(OC)=CC=C1CCC(=O)C(C(=C1)O)=C(O)C=C1O[C@H]1[C@H](O[C@H]2[C@@H]([C@H](O)[C@@H](O)[C@H](C)O2)O)[C@@H](O)[C@H](O)[C@@H](CO)O1 ITVGXXMINPYUHD-CUVHLRMHSA-N 0.000 description 1
- 229940089953 neohesperidin dihydrochalcone Drugs 0.000 description 1
- 235000010434 neohesperidine DC Nutrition 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 235000020824 obesity Nutrition 0.000 description 1
- 230000007918 pathogenicity Effects 0.000 description 1
- 229960000292 pectin Drugs 0.000 description 1
- 235000011007 phosphoric acid Nutrition 0.000 description 1
- 239000003075 phytoestrogen Substances 0.000 description 1
- 229940068065 phytosterols Drugs 0.000 description 1
- 239000000419 plant extract Substances 0.000 description 1
- 235000013856 polydextrose Nutrition 0.000 description 1
- 239000001259 polydextrose Substances 0.000 description 1
- 229940035035 polydextrose Drugs 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 239000004224 potassium gluconate Substances 0.000 description 1
- 229960003189 potassium gluconate Drugs 0.000 description 1
- 235000013926 potassium gluconate Nutrition 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 238000011002 quantification Methods 0.000 description 1
- MUPFEKGTMRGPLJ-ZQSKZDJDSA-N raffinose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O2)O)O1 MUPFEKGTMRGPLJ-ZQSKZDJDSA-N 0.000 description 1
- 238000005057 refrigeration Methods 0.000 description 1
- 235000021254 resistant starch Nutrition 0.000 description 1
- 229940100486 rice starch Drugs 0.000 description 1
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 235000019615 sensations Nutrition 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- 238000004513 sizing Methods 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 235000019265 sodium DL-malate Nutrition 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- 239000000176 sodium gluconate Substances 0.000 description 1
- 229940005574 sodium gluconate Drugs 0.000 description 1
- 235000012207 sodium gluconate Nutrition 0.000 description 1
- 239000001540 sodium lactate Substances 0.000 description 1
- 235000011088 sodium lactate Nutrition 0.000 description 1
- 229940005581 sodium lactate Drugs 0.000 description 1
- 239000001394 sodium malate Substances 0.000 description 1
- GSZUGBAEBARHAW-UHFFFAOYSA-N sophoraflavone B Natural products OC1C(O)C(O)C(CO)OC1OC1=CC=C(C=2OC3=CC(O)=CC=C3C(=O)C=2)C=C1 GSZUGBAEBARHAW-UHFFFAOYSA-N 0.000 description 1
- 229960002920 sorbitol Drugs 0.000 description 1
- 235000019614 sour taste Nutrition 0.000 description 1
- 235000019710 soybean protein Nutrition 0.000 description 1
- 235000013599 spices Nutrition 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 235000010491 tara gum Nutrition 0.000 description 1
- 239000000213 tara gum Substances 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 235000019640 taste Nutrition 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 description 1
- 229940038773 trisodium citrate Drugs 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
- 239000000811 xylitol Substances 0.000 description 1
- 235000010447 xylitol Nutrition 0.000 description 1
- 229960002675 xylitol Drugs 0.000 description 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
Images
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Description
本創作係關於一種顆粒結構,尤係關於一種包埋有機酸之顆粒結構。 This creation is about a granular structure, especially a granular structure embedding an organic acid.
含有機酸成分之飲品在進行粉末化之過程常使用高溫噴霧乾燥;然而,產品中的有機酸容易因高溫而被破壞或揮發逸散,因此無法有效達到保留有機酸以作為保健品的成分。再者,自製發酵飲品保存階段的低溫冷藏效期多僅能保存1周,且保存過程不可避免地將產生能耗成本。 Beverages containing organic acid ingredients are often spray-dried at high temperature during the powderization process; however, the organic acid in the product is easily destroyed or volatilized due to high temperature, so it is impossible to effectively retain the organic acid as an ingredient in health care products. Furthermore, the low-temperature refrigeration in the preservation stage of the self-made fermented beverage can only be preserved for one week at most, and the preservation process will inevitably generate energy costs.
此外,為了增加產品溶解度,一般即溶粉末飲品係以不同配方組成的粉末混合而得,因其混拌過程中易產生吸濕的問題,故配方中常添加二氧化矽作為抗結塊劑。然而,抗結塊劑對於食用者之健康無益,食用過量反而造成身體負擔。 In addition, in order to increase the solubility of the product, instant powder drinks are generally obtained by mixing powders with different formulations. Because of the problem of moisture absorption during the mixing process, silicon dioxide is often added to the formulation as an anti-caking agent. However, anti-caking agents are not beneficial to the health of the eaters, and excessive consumption will cause physical burden.
因此,本領域亟需可同時克服上述問題的產品。 Therefore, there is an urgent need in the art for products that can overcome the above-mentioned problems simultaneously.
有鑑於上述問題,本創作提供一種能包埋有機酸及其它活性物 質之顆粒結構,其包含核心、包覆該核心的調味殼層及包覆該調味殼層的保護層,其中,該核心包含功能性成分,且該功能性成分包含纖維和紅茶菌菇發酵液。 In view of the above problems, this creation provides a kind of can embedding organic acid and other active substances A qualitative granular structure comprising a core, a seasoning shell covering the core, and a protective layer covering the seasoning shell, wherein the core contains functional ingredients, and the functional ingredients include fiber and kombucha fermented liquid .
於本創作之至少一具體實施例中,該核心進一步包含紅茶粉。 In at least one embodiment of the present invention, the core further comprises black tea powder.
於本創作之至少一具體實施例中,該顆粒結構之平均粒徑至少為0.2mm。於本創作之一些具體實施例中,該顆粒結構之平均粒徑為0.2mm至0.5mm。 In at least one embodiment of the present invention, the average particle size of the granular structure is at least 0.2 mm. In some specific embodiments of the present invention, the average particle size of the granular structure is 0.2 mm to 0.5 mm.
於本創作之至少一具體實施例中,該纖維係選自由可溶性纖維、菊苣纖維、果寡糖所組成群組之其中之一或其組合。 In at least one specific embodiment of the present invention, the fiber is selected from one or a combination of the group consisting of soluble fiber, chicory fiber, and fructooligosaccharide.
於本創作之至少一具體實施例中,該功能性成分另包含幫助保存有機酸之有效成分、載劑、賦形劑或其組合。 In at least one specific embodiment of the present invention, the functional ingredient further includes an active ingredient, a carrier, an excipient or a combination thereof to help preserve the organic acid.
於本創作之至少一具體實施例中,該紅茶菌菇發酵液包含有機酸或益生菌。於本創作之一些具體實施例中,該益生菌為乳酸菌。 In at least one specific embodiment of the present invention, the kombucha fermented liquid contains organic acids or probiotics. In some specific embodiments of the present invention, the probiotics are lactic acid bacteria.
於本創作之至少一具體實施例中,該有機酸係選自由醋酸、檸檬酸、琥珀酸、草酸、葡萄糖醛酸及葡萄糖酸所組成群組之其中之一或其組合。 In at least one embodiment of the present invention, the organic acid is one or a combination selected from the group consisting of acetic acid, citric acid, succinic acid, oxalic acid, glucuronic acid and gluconic acid.
於本創作之至少一具體實施例中,該調味殼層包含香氣微膠囊及調味成分。 In at least one specific embodiment of the present invention, the flavoring shell layer includes aroma microcapsules and flavoring ingredients.
於本創作的一些具體實施例中,該核心係由紅茶菌菇發酵液經噴霧造粒而製成,故能有效防止紅茶菌菇發酵液中的有機酸成分被破壞或揮發逸散,且將粉體原料製備成顆粒狀能改善粉體的流動性及溶解性。此外,調味殼層除了具有調味或調香成分,還具有保護包埋其中有機酸成分 之功效,亦可視實際需求設計為緩釋型調味殼層。另外,保護層具有抗吸濕功能,以取代一般粉末混拌工段所添加的抗結塊劑。 In some specific embodiments of this creation, the core is made of kombucha fermented liquid through spray granulation, so it can effectively prevent the organic acid components in the kombucha fermented liquid from being destroyed or volatilized, and will Preparation of powder raw materials into granules can improve the fluidity and solubility of powder. In addition, in addition to flavoring or flavoring ingredients, the seasoning shell also has the protection of organic acid ingredients embedded in it. It can also be designed as a slow-release seasoning shell according to actual needs. In addition, the protective layer has anti-moisture absorption function to replace the anti-caking agent added in the general powder mixing section.
本創作另提供一種製備上述顆粒結構之方法,其包含將該功能性成分過篩;混合及乾燥該功能性成分;將該功能性成分進行噴霧造粒以形成該核心;以及形成包覆該核心之調味殼層及保護層。 The present invention also provides a method for preparing the above granular structure, which includes sieving the functional ingredient; mixing and drying the functional ingredient; spraying and granulating the functional ingredient to form the core; and forming a coating on the core Seasoning shell and protective layer.
於本創作之至少一具體實施例中,該紅茶菌菇發酵液係藉由噴霧造粒以形成該核心。於本創作之一些具體實施例中,係使用流動床噴霧造粒製程將該紅茶粉、纖維和紅茶菌菇發酵液或其他功能性成分快速且均勻包覆混合。 In at least one embodiment of the present invention, the kombucha fermented liquid is spray granulated to form the core. In some specific embodiments of the present invention, the black tea powder, fiber and kombucha fermented liquid or other functional ingredients are quickly and uniformly coated and mixed by using a fluidized bed spray granulation process.
於本創作之至少一具體實施例中,該噴霧造粒之溫度為30℃至90℃、37℃至43℃、40℃至80℃、77℃至83℃、52℃至74℃、57℃至63℃、49℃至62℃或61℃至69℃。於一些具體實施例中,該噴霧造粒之溫度可為約31℃、33℃、35℃、37℃、39℃、41℃、43℃、45℃、47℃、49℃、51℃、53℃、55℃、57℃、59℃、61℃、63℃、65℃、67℃、69℃、71℃、73℃、75℃、77℃、79℃、81℃、83℃、85℃、87℃、89℃,但本創作不以此為限。 In at least one specific embodiment of the present creation, the temperature of the spray granulation is 30°C to 90°C, 37°C to 43°C, 40°C to 80°C, 77°C to 83°C, 52°C to 74°C, 57°C to 63°C, 49°C to 62°C, or 61°C to 69°C. In some specific embodiments, the temperature of the spray granulation can be about 31°C, 33°C, 35°C, 37°C, 39°C, 41°C, 43°C, 45°C, 47°C, 49°C, 51°C, 53°C ℃, 55℃, 57℃, 59℃, 61℃, 63℃, 65℃, 67℃, 69℃, 71℃, 73℃, 75℃, 77℃, 79℃, 81℃, 83℃, 85℃, 87℃, 89℃, but this creation is not limited to this.
於本創作之至少一具體實施例中,係使用流動床噴霧造粒機以約57℃至63℃進行顆粒原料混拌與包覆造粒,該顆粒原料包含纖維和紅茶菌菇發酵液;在核心表面以調味成分做包覆形成調味殼層;以及在該調味殼層之外層以再以包埋技術形成保護層。於本創作的一些具體實施例中,該保護層為抗吸濕保護層,以形成微膠囊顆粒之設計,故無需額外添加抗結塊劑。 In at least one specific embodiment of this creation, a fluidized bed spray granulator is used to mix and coat granules at about 57°C to 63°C. The granule raw materials include fiber and kombucha fermentation broth; The surface of the core is covered with seasoning ingredients to form a seasoning shell; and the outer layer of the seasoning shell is further formed with an embedding technique to form a protective layer. In some embodiments of the present invention, the protective layer is an anti-moisture-absorbing protective layer to form microcapsule particles, so no additional anti-caking agent is needed.
本創作之顆粒結構較一般紅茶菌菇飲品產品結構均勻,故可改善粉體之流動性與溶解性。此外,本創作所採用之特定溫度範圍的噴霧造粒製程,除了保留有機酸成分外,還在表面以調味成分做包覆形成調味殼層,包埋並保護其有機酸成分,最後以包覆形成保護層進行微膠囊顆粒的設計,以取代一般粉末混拌工段所添加的抗結塊劑,達到粉末的抗吸濕之保存性。整體而言,本創作改善即溶茶飲品粉體之均勻性,並提升其流動性與即溶沖泡下的溶解性;以特定溫度包埋與保存發酵紅茶菌菇中的機能有機酸成分,以達到健康化的效果;提升即溶茶飲品的抗吸濕與保存性,無添加抗結塊劑的配方組合符合食品潔淨標籤(Clean label)的演進概念,強化保健品的健康價值。 The particle structure of this creation is more uniform than that of ordinary kombucha mushroom beverage products, so it can improve the fluidity and solubility of the powder. In addition, the spray granulation process in a specific temperature range used in this creation not only retains the organic acid components, but also coats the surface with flavoring ingredients to form a seasoning shell, embeds and protects the organic acid components, and finally coats them with Form a protective layer for the design of microcapsule particles to replace the anti-caking agent added in the general powder mixing process to achieve the preservation of the powder against moisture absorption. On the whole, this creation improves the uniformity of instant tea drink powder, and improves its fluidity and solubility under instant brewing; the functional organic acid components in fermented kombucha mushrooms are embedded and preserved at a specific temperature, In order to achieve a healthy effect; improve the anti-moisture absorption and preservation of instant tea drinks, and the formula combination without adding anti-caking agents conforms to the evolution concept of food clean labels (Clean label), and strengthens the health value of health care products.
本創作之顆粒結構可直接添加至飲用水或其他飲品中,以增添風味。當本創作之顆粒結構接觸飲品後,該顆粒結構之調味殼層可使功能性成分及調味劑釋放。於本案之一具體實施例中,該保護層接觸該飲品後將產生崩解、分解或溶解,使該功能性成分及該調味劑釋放於該飲品中。該功能性成分例如有機酸及纖維,有益於食用者之身體健康,且該功能性成分還可包括促進保存有機酸之有效成分,有益於促進吸收有機酸。此外,本創作減少使用抗結塊劑,以包埋技術取代一般粉末混拌工段所添加的抗結塊劑,達到粉末的抗吸濕之保存性,因此增加整體保存時間。 The granular structure of this creation can be added directly to drinking water or other beverages to add flavor. When the particle structure of the invention contacts the beverage, the flavoring shell of the particle structure can release the functional ingredients and flavoring agent. In a specific embodiment of the present case, the protective layer will disintegrate, decompose or dissolve after contacting the drink, so that the functional ingredient and the flavoring agent are released in the drink. The functional ingredients, such as organic acid and fiber, are beneficial to the health of the eater, and the functional ingredient can also include active ingredients that promote the preservation of organic acids, which are beneficial to promote the absorption of organic acids. In addition, this creation reduces the use of anti-caking agents and uses embedding technology to replace the anti-caking agents added in the general powder mixing process to achieve the anti-moisture storage of the powder, thus increasing the overall storage time.
因此,本創作之顆粒結構可兼顧飲品之方便性、健康益處及保存效果,強化作為保健品的健康價值。 Therefore, the particle structure of this creation can take into account the convenience, health benefits and preservation effect of drinks, and strengthen the health value as a health product.
100:顆粒結構 100: Granular structure
11:紅茶粉 11: black tea powder
12:纖維 12: Fiber
13:紅茶菌菇發酵液 13: Kombucha fermented liquid
21:香氣微膠囊 21: Aroma microcapsules
22:調味殼層 22: Seasoned Shells
23:保護層 23: Protective layer
a~f:步驟 a~f: steps
圖1係本創作之一具體實施例中製備顆粒結構的方法流程圖。 Fig. 1 is the flow chart of the method for preparing the granular structure in one of the specific embodiments of this creation.
圖2係本創作之一具體實施例中之顆粒結構的剖面示意圖。 Fig. 2 is a schematic cross-sectional view of the granular structure in a specific embodiment of the invention.
以下係藉由特定的具體實施例說明本創作之實施方式,本創作所屬技術領域中具有通常知識者可依據本說明書所揭示之內容輕易地瞭解本創作之精神、優點及功效。然而,本創作之具體實施例並非用以限定本創作,本創作亦可藉由其它不同之實施方式加以實現或應用,本說明書所載各項細節亦可根據不同的觀點與應用,在不悖離本創作之精神下賦予不同的變化或修飾。 The implementation of this creation is described below through specific specific examples. Those with ordinary knowledge in the technical field of this creation can easily understand the spirit, advantages and effects of this creation based on the content disclosed in this specification. However, the specific embodiments of this creation are not intended to limit this creation. This creation can also be realized or applied through other different implementation methods. The details contained in this specification can also be based on different viewpoints and applications, without prejudice to Different changes or modifications are given under the spirit of the original creation.
本文所述「包括」或「包含」組成分或步驟時,除非另有說明,否則可另包含其他組成分或其他步驟,而非排除該等其他組成分或其他步驟。此外,除非本文另有明確說明,否則本文所述單數形式之「一」及「該」包含複數指示物,且本文所述「或」係與「及/或」互換使用。 When "comprising" or "comprising" components or steps described herein, unless otherwise stated, other components or other steps may be included, rather than excluded. In addition, unless otherwise specified herein, the singular forms of "a" and "the" herein include plural referents, and "or" herein is used interchangeably with "and/or".
本文所述之數值範圍係包含及可合併的,落在本文所述數值範圍內之任何數值,都可以作為最大值或最小值以導出次範圍;舉例而言,「0.2mm至0.5mm」之數值範圍應可理解為包含最小值0.2mm及最大值0.5mm之間的任何次範圍,例如:0.2mm至0.4mm、0.3mm至0.5mm及0.35mm至0.45mm等次範圍。此外,本文所述的多個數值可以選擇性被選為最大值或最小值以導出數值範圍;舉例而言,41℃、53℃、65℃可以導出41℃至53℃、41℃至65℃、53℃至65℃的數值範圍。另外,本文所 述之百分比符號「%」,除非另有特別說明,否則表示重量百分比。 The numerical ranges described herein are inclusive and combinable, and any value falling within the numerical ranges stated herein can be used as the maximum or minimum value to derive the sub-range; for example, "0.2mm to 0.5mm" The numerical range should be understood as including any sub-range between the minimum value of 0.2mm and the maximum value of 0.5mm, for example: 0.2mm to 0.4mm, 0.3mm to 0.5mm and 0.35mm to 0.45mm and other subranges. In addition, various values described herein can be selectively selected as maximum or minimum values to derive ranges of values; for example, 41°C, 53°C, 65°C can lead to 41°C to 53°C, 41°C to 65°C , The range of values from 53°C to 65°C. In addition, this article The above-mentioned percentage symbol "%" means percentage by weight unless otherwise specified.
如本文中所使用,術語「約」通常係指數值旨在包含於給定的數值或範圍具有±20%、±10%、±5%、±1%、±0.5%、±0.1%的偏差。該數值偏差可因為,如實驗誤差;製備化合物、組成物、濃縮物、配方之測量標準誤或處理流程;本創作之來源、製造、起始材料或成分的純度;類似的考量因素而出現。或者,當由所屬領域具中具有通常知識者考量時,術語「約」意指介於可接受的平均值的標準誤差內。除非明確地界定,所有數值範圍、量、數值、比例像是於本文中所揭露的材料、時段的持續時間、溫度、執行的條件、含量的比例、其類似物之定量,應理解為在所有情況下皆由術語「約」修飾。 As used herein, the term "about" generally means that the value is intended to include a deviation of ±20%, ±10%, ±5%, ±1%, ±0.5%, ±0.1% from the given value or range . Deviations from this value may arise due to, for example, experimental error; standard errors of measurement or processing procedures for preparing compounds, compositions, concentrates, formulations; source, manufacture, purity of starting materials or ingredients of this work; and similar considerations. Alternatively, the term "about" means within an acceptable standard error of the mean when considered by one of ordinary skill in the art. Unless expressly defined, all numerical ranges, amounts, values, ratios such as disclosed herein for materials, durations of time periods, temperatures, conditions of performance, ratios of contents, quantification of the like, are to be understood in all Both cases are modified by the term "about".
本創作包埋有機酸及活性物質之顆粒結構包含核心、調味殼層及保護層,其中,該核心包含功能性成分,且該功能性成分可包含幫助保存有機酸之有效成分、載劑、賦形劑或其組合;該調味殼層包覆該核心;該保護層包覆整個顆粒結構。 The granular structure of the present invention embedding organic acids and active substances includes a core, a seasoning shell and a protective layer, wherein the core contains functional ingredients, and the functional ingredients can include active ingredients that help preserve organic acids, carriers, excipients, etc. Forming agents or combinations thereof; the seasoning shell coats the core; the protective layer coats the entire particle structure.
本創作用於製備包埋有機酸及活性物質之顆粒結構的方法包含:將功能性成分與載劑或賦形劑混合,將顆粒原料製成均勻的顆粒狀和核心,其中,該功能性成分包含纖維和紅茶菌菇發酵液;以及在該核心之表面以調味成分形成調味殼層,以包覆該核心;最後,以包埋技術完成保護層以包覆該調味殼層。上述載劑或賦形劑為食品上或生理上可接受之載劑或賦形劑。 The method used in the present invention to prepare a particle structure embedding organic acids and active substances includes: mixing functional components with carriers or excipients, making the particle raw materials into uniform particles and cores, wherein the functional components Containing fiber and kombucha fermented liquid; and forming a seasoning shell with seasoning ingredients on the surface of the core to cover the core; finally, completing a protective layer with embedding technology to cover the seasoning shell. The above-mentioned carriers or excipients are food or physiologically acceptable carriers or excipients.
於本創作之一具體實施例中,該顆粒結構幫助保存有機酸,故有益於促進吸收有機酸,該顆粒結構包含以下:核心、調味殼層及保護層。 較佳地,平均粒徑為至少0.2mm。於本創作之另一具體實施例中,該顆粒結構之平均粒徑為0.2mm至0.5mm,例如但不限於約0.25mm、0.30mm、0.35mm、0.4mm、0.45mm或0.5mm。於本創作之又一具體實施例中,該顆粒結構之平均粒徑為0.3mm至0.5mm,較佳地,該顆粒結構之平均粒徑為0.4mm至0.5mm。於本創作之至少一具體實施例中,該顆粒結構之粒徑為0.1mm至1.5mm,例如但不限於0.1mm、0.2mm、0.3mm、0.4mm、0.5mm、0.6mm、0.7mm、0.8mm、0.9mm、1.0mm、1.1mm、1.2mm、mm、1.3mm、1.4mm或1.5mm。 In one embodiment of the present invention, the granular structure helps preserve the organic acid, so it is beneficial to promote the absorption of the organic acid. The granular structure includes the following: a core, a seasoning shell and a protective layer. Preferably, the average particle size is at least 0.2 mm. In another embodiment of the present invention, the particle structure has an average particle size of 0.2mm to 0.5mm, such as but not limited to about 0.25mm, 0.30mm, 0.35mm, 0.4mm, 0.45mm or 0.5mm. In yet another specific embodiment of the present invention, the average particle size of the granular structure is 0.3 mm to 0.5 mm, preferably, the average particle size of the granular structure is 0.4 mm to 0.5 mm. In at least one specific embodiment of the present creation, the particle size of the granular structure is 0.1mm to 1.5mm, such as but not limited to 0.1mm, 0.2mm, 0.3mm, 0.4mm, 0.5mm, 0.6mm, 0.7mm, 0.8mm mm, 0.9mm, 1.0mm, 1.1mm, 1.2mm, mm, 1.3mm, 1.4mm or 1.5mm.
於本創作之一具體實施例中,該顆粒結構之形狀係選自由圓球體、橢圓球體、立方體、圓柱體、長方體、四面體、椎體、星形、心形、扇形及貝殼形所組成群組之其中之一或其組合。 In a specific embodiment of the invention, the shape of the granular structure is selected from the group consisting of sphere, ellipsoid, cube, cylinder, cuboid, tetrahedron, cone, star, heart, sector and shell. one or a combination of the groups.
於本創作之一具體實施例中,該核心之粒徑或平均粒徑為0.01mm至0.3mm,例如但不限於0.02mm至0.1mm、0.02mm至0.15mm、0.06mm至0.08mm或0.1mm至0.3mm。 In a specific embodiment of the present invention, the particle size or average particle size of the core is 0.01mm to 0.3mm, such as but not limited to 0.02mm to 0.1mm, 0.02mm to 0.15mm, 0.06mm to 0.08mm or 0.1mm to 0.3mm.
於本創作之一具體實施例中,該核心、調味殼層及保護層進一步包含食品上或生理上可接受之載劑或賦形劑。本創作之食品上或生理上可接受之載劑或賦形劑包括但不限於澱粉(例如:米澱粉、小麥澱粉、玉米澱粉及小麥澱粉)、乳糖、蔗糖、葡萄糖、玉米甜味劑、糊精、環糊精、麥芽糖糊精、抗性澱粉、玉米來源可溶性纖維、菊苣纖維、寡糖、木質素、幾丁質、半纖維素、戊聚糖、β-葡聚糖、半乳甘露聚糖、甲殼素、樹膠、大豆膳食纖維、羧甲基澱粉鈉、丙酸羧基化澱粉、微晶纖維素、羧甲基纖維素、羧甲基纖維素鈉、羥丙基甲基纖維素、甘露醇、山梨糖醇、硬脂酸鎂、 磷酸二鈣、明膠、瓊脂、果膠、阿拉伯膠、海藻酸鈉、鹿角菜膠、刺槐豆膠、關華豆膠、塔拉膠、蒟蒻膠、黃耆膠、玉米糖膠、結蘭膠、卡德蘭膠、蟲膠、水或其中二者以上之組合。較佳地,該食品上或生理上可接受之載劑或賦形劑為澱粉、乳糖或其組合。較佳地,該食品上或生理上可接受之載劑或賦形劑為澱粉、寡糖、糊精、玉米來源可溶性纖維、菊苣纖維、果寡糖或其中兩者以上之組合。於本創作之一具體實施例中,該保護層包含膠體,例如但不限於明膠、阿拉伯膠、海藻酸鈉、瓊脂、果膠、蟲膠、羧甲基纖維素、鹿角菜膠、玉米糖膠、褐藻酸鈉、結蘭膠、關華豆膠、塔拉膠或羥丙基甲基纖維素或其中兩者以上之組合。 In one embodiment of the present invention, the core, seasoning shell and protective layer further comprise food or physiologically acceptable carriers or excipients. Food or physiologically acceptable carriers or excipients of this invention include but are not limited to starch (such as: rice starch, wheat starch, corn starch and wheat starch), lactose, sucrose, glucose, corn sweetener, paste Ethrin, cyclodextrin, maltodextrin, resistant starch, soluble fiber from corn, chicory fiber, oligosaccharides, lignin, chitin, hemicellulose, pentosan, beta-glucan, galactomannan Sugar, chitin, gum, soybean dietary fiber, sodium carboxymethyl starch, carboxylated starch propionate, microcrystalline cellulose, carboxymethyl cellulose, sodium carboxymethyl cellulose, hydroxypropyl methyl cellulose, manna Alcohol, Sorbitol, Magnesium Stearate, Dicalcium Phosphate, Gelatin, Agar, Pectin, Gum Arabic, Sodium Alginate, Carrageenan, Locust Bean Gum, Guanhua Bean Gum, Tara Gum, Konjac Gum, Tragacanth Gum, Corn Sugar Gum, Gelan Gum, Cadlan gum, shellac, water or a combination of two or more. Preferably, the food or physiologically acceptable carrier or excipient is starch, lactose or a combination thereof. Preferably, the food or physiologically acceptable carrier or excipient is starch, oligosaccharide, dextrin, corn-derived soluble fiber, chicory fiber, fructooligosaccharide or a combination of two or more thereof. In a specific embodiment of the present invention, the protective layer comprises colloids, such as but not limited to gelatin, gum arabic, sodium alginate, agar, pectin, shellac, carboxymethyl cellulose, carrageenan, corn sugar , sodium alginate, gellan gum, Guanhua bean gum, tara gum or hydroxypropyl methylcellulose or a combination of two or more of them.
本文中的術語「功能性成分」係指於食品中提供食用者超出基本營養價值且對健康有益處的成分,可增進食用者之身體健康及/或降低食用者罹患疾病之風險,例如:促進腸胃道健康、幫助消化、強健骨骼、保健牙齒、清新口氣、緩解壓力及緊張、改善或預防心血管疾病、糖尿病、肥胖症或骨質疏鬆症等。本創作之功能性成分包括但不限於纖維、紅茶菌菇發酵液、益生質、益生菌、提升專注力之有效成分、膳食纖維、維生素、礦物質、類胡蘿蔔素、類黃酮、酶、抗氧化劑、植物雌激素、植物固醇、軟磷脂、脂肪酸、胺基酸、肌酸、蛋白質(例如大豆蛋白質或膠原蛋白)、咖啡因、胜肽、植物萃取物、菇菌類菌絲體、菇菌類子實體、蟲草類菌絲體、蟲草類子實體或其中二者以上之組合。於本創作之一具體實施例中,該功能性成分係選自由紅茶菌菇發酵飲品製造過程中產生的有機酸包含但不限於醋酸。 The term "functional ingredients" in this article refers to ingredients that provide consumers with health benefits beyond the basic nutritional value in food, which can improve the health of consumers and/or reduce the risk of diseases for consumers, such as: promoting Gastrointestinal health, aid digestion, strengthen bones, protect teeth, freshen breath, relieve stress and tension, improve or prevent cardiovascular disease, diabetes, obesity or osteoporosis, etc. The functional ingredients of this creation include but are not limited to fiber, kombucha fermented liquid, prebiotics, probiotics, effective ingredients for improving concentration, dietary fiber, vitamins, minerals, carotenoids, flavonoids, enzymes, antioxidants , phytoestrogens, phytosterols, lecithin, fatty acids, amino acids, creatine, proteins (such as soybean protein or collagen), caffeine, peptides, plant extracts, mushroom mycelium, mushroom seeds Entity, Cordyceps mycelium, Cordyceps fruiting body or a combination of two or more of them. In one embodiment of the invention, the functional ingredient is selected from organic acids produced during the production of kombucha mushroom fermented beverage including but not limited to acetic acid.
本文中的術語「益生質」係指一種或多種食品成份,其可選擇 性刺激益生菌在宿主消化道中的生長或活性,進而達到促進宿主健康之效果。於本創作之一具體實施例中,該益生質係選自由醣類、糖醇及地靈粉末所組成群組之其中之一或其組合。較佳地,該醣類為寡醣或多醣。較佳地,該醣類係選自由木寡醣、大豆寡醣、膳食纖維、果寡醣(fructo-oligosaccharide,FOS)、異麥芽寡醣、乳果寡醣、乳酮糖、半乳寡醣(galacto-oligosaccharide,GOS)、棉子糖、菊苣纖維(菊糖)、聚糊精、聚葡萄糖、葡萄寡醣、甘露寡醣、阿拉伯寡醣、岩藻寡醣(fuco-oligosaccharide)、殼寡醣(chito-oligosaccharide)、乳糖醇及乳酮糖所組成群組之其中之一或其組合。於本創作之一具體實施例中,該益生質係選自由膳食纖維、寡糖、低聚醣所組成群組之其中之一或其組合,較佳地,該寡糖為果寡糖、半乳寡糖、菊苣纖維或其中兩者以上之組合。 As used herein, the term "prebiotic" refers to one or more food ingredients, which optionally Sexually stimulate the growth or activity of probiotics in the digestive tract of the host, thereby achieving the effect of promoting the health of the host. In a specific embodiment of the present creation, the prebiotic is selected from one or a combination of sugars, sugar alcohols, and ground spirit powder. Preferably, the carbohydrates are oligosaccharides or polysaccharides. Preferably, the carbohydrates are selected from xylooligosaccharides, soybean oligosaccharides, dietary fiber, fructo-oligosaccharides (FOS), isomaltooligosaccharides, lactulose oligosaccharides, lactulose, galactooligosaccharides Sugar (galacto-oligosaccharide, GOS), raffinose, chicory fiber (inulin), polydextrin, polydextrose, glucose oligosaccharide, mannan oligosaccharide, arabinoid oligosaccharide, fuco-oligosaccharide (fuco-oligosaccharide), shell One or a combination of the group consisting of oligosaccharides (chito-oligosaccharide), lactitol and lactulose. In a specific embodiment of the present creation, the prebiotic is selected from one or a combination of the group consisting of dietary fiber, oligosaccharides, and oligosaccharides. Preferably, the oligosaccharides are fructooligosaccharides, semi- Milk oligosaccharides, chicory fiber or a combination of two or more thereof.
本文中的術語「益生菌」係指有益於宿主健康且無致病性或低致病性的微生物。於本創作之至少一具體實施例中,該益生菌係選自由芽孢乳酸菌(Bacillus coagulans)、比菲德氏菌(Bifidobacterium bifidum)、短雙歧桿菌(Bifidobacterium breve)、長雙歧桿菌(Bifidobacterium infants)、動物雙歧桿菌(Bifidobacterium lactis)、比菲德氏龍根菌(Bifidobacterium longum)、嗜酸乳桿菌(Lactobacillus acidophilus)、短乳桿菌(Lactobacillus brevis)、保加利亞乳桿菌(Lactobacillus bulgaricus)、乾酪乳桿菌(Lactobacillus casei)、酵素乳桿菌(Lactobacillus fermentum)、加氏乳桿菌(Lactobacillus gasseri)、瑞士乳桿菌(Lactobacillus helveticus)、約氏乳桿菌(Lactobacillus johnsonii)、副乾酪乳桿菌(Lactobacillus paracasei)、戊糖乳桿菌(Lactobacillus pentosus)、胚芽乳酸菌(Lactobacillus plantarum)、洛德乳桿菌(Lactobacillus reuteri)、鼠李糖乳桿菌(Lactobacillus rhamnosus)、唾液乳桿菌(Lactobacillus salivarius)、乳酸乳球菌(Lactococcus lactis)、嗜熱鏈球菌(Streptococcus thermophiles)、戊糖片球菌(Pediococcus pentosaceus)、乳酸片球菌(Pediococcus acidilactici)及青春雙歧桿菌(Bifidobacterium adolescentis)所組成群組之其中之一或其組合。較佳地,該益生菌係選自由動物雙歧桿菌(Bifidobacterium lactis)、酵素乳桿菌(Lactobacillus fermentum)、胚芽乳酸菌(Lactobacillus plantarum)及副乾酪乳桿菌(Lactobacillus paracasei)所組成群組之其中之一或其組合。 The term "probiotics" herein refers to microorganisms that are beneficial to the health of the host and have no or low pathogenicity. In at least one specific embodiment of the present creation, the probiotics are selected from Bacillus coagulans , Bifidobacterium bifidum , Bifidobacterium breve , Bifidobacterium infants ), Bifidobacterium lactis, Bifidobacterium longum , Lactobacillus acidophilus , Lactobacillus brevis , Lactobacillus bulgaricus , cheese milk Lactobacillus casei , Lactobacillus fermentum , Lactobacillus gasseri, Lactobacillus helveticus , Lactobacillus johnsonii, Lactobacillus paracasei, Lactobacillus pentosus , Lactobacillus plantarum , Lactobacillus reuteri , Lactobacillus rhamnosus , Lactobacillus salivarius , Lactococcus lactis , One or a combination of the group consisting of Streptococcus thermophiles, Pediococcus pentosaceus , Pediococcus acidilactici and Bifidobacterium adolescentis . Preferably, the probiotics are selected from the group consisting of Bifidobacterium lactis , Lactobacillus fermentum , Lactobacillus plantarum and Lactobacillus paracasei or a combination thereof.
於本創作之至少一具體實施例中,該顆粒結構之紅茶粉係選自由錫蘭紅茶粉、伯爵紅茶粉、阿薩姆紅茶粉、大吉嶺紅茶粉所組成群組之其中之一或其組合。 In at least one specific embodiment of the present creation, the black tea powder with granular structure is selected from the group consisting of Ceylon black tea powder, Earl Gray black tea powder, Assam black tea powder, Darjeeling black tea powder or a combination thereof .
於本創作之至少一具體實施例中,該顆粒結構之纖維係選自由可溶性纖維、菊苣纖維、果寡糖所組成群組之其中之一或其組合。 In at least one specific embodiment of the present invention, the granular fiber is selected from one or a combination of soluble fiber, chicory fiber, and fructooligosaccharide.
於本創作之至少一具體實施例中,該紅茶菌菇發酵液進一步包含有機酸或益生菌。於本創作之一些具體實施例中,該紅茶菌菇發酵液之有機酸係選自由醋酸、檸檬酸、琥珀酸、草酸、葡萄糖醛酸及葡萄糖酸所組成群組之其中之一或其組合。於本創作之一些具體實施例中,該益生菌為乳酸菌。 In at least one specific embodiment of the present invention, the kombucha fermented liquid further includes organic acids or probiotics. In some specific embodiments of the present creation, the organic acid of the kombucha fermented liquid is selected from one or a combination of acetic acid, citric acid, succinic acid, oxalic acid, glucuronic acid and gluconic acid. In some specific embodiments of the present invention, the probiotics are lactic acid bacteria.
本文中的術語「釋放」係指在特定外界環境下,例如但不限於在液體中,本創作之顆粒結構將其所包含之成分向外界遞送的特性。於本 創作之一具體實施例中,該保護層可以提升本創作之顆粒結構之抗吸濕和保存性。於本創作之一具體實施例中,該調味殼層具有釋放該功能性成分之作用,例如該保護層及調味殼層於液體中崩解、分解或溶解,以釋放該功能性成分。於本創作之一具體實施例中,該液體為飲品,較佳為飲用水。 The term "release" herein refers to the property of the granular structure of the present invention to deliver its contained components to the outside under a specific external environment, such as but not limited to in a liquid. Yu Ben In a specific embodiment of the creation, the protective layer can improve the anti-moisture absorption and storage properties of the granular structure of the creation. In a specific embodiment of the present invention, the flavoring shell has the function of releasing the functional ingredient, for example, the protective layer and the flavoring shell disintegrate, decompose or dissolve in the liquid to release the functional ingredient. In a specific embodiment of the invention, the liquid is a beverage, preferably drinking water.
本文中的術語「調味劑」係指食品上或生理上可接受之天然、合成或半合成物質,其在食用者體內誘發味覺、嗅覺、觸覺等感受,其中,在食用者體內誘發甜味感受者為「甜味劑」;在食用者體內誘發酸味感受者為「酸味劑」。本創作之甜味劑包括但不限於天然植物來源所獲得之汁液、粉末、糖漿、萃取物、濃縮物或香料,該天然植物來源例如:巧克力、檸檬、草莓、香蕉、莓果、芒果、哈密瓜、百香果、鳳梨、水蜜桃、櫻桃、肉桂、蘋果、茴香、蜂蜜、梨、楓糖、葡萄、葡萄柚、柳橙、橘子、西瓜、羅漢果、蘑菇或香草;醣類甜味劑包括但不限於乳糖、半乳寡糖、蔗糖、果糖、麥芽糖、葡萄糖或砂糖;糖醇類甜味劑包括但不限於木糖醇、甘露糖醇、山梨糖醇、赤藻糖醇、異麥芽酮糖醇、甜菊糖苷、赤藻糖醇或乳糖醇;以及人工甜味劑包括但不限於阿斯巴甜或其衍生物、乙醯磺胺酸鉀、新橙皮苷二氫查耳酮、甘草素、醋磺內酯鉀或蔗糖素。於本創作之一具體實施例中,該甜味劑為羅漢果萃取物、甜菊糖苷、蘑菇萃取物或其中兩者以上之組合。另一具體實施例中,該甜味劑為羅漢果萃取物、蔗糖素、醋磺內酯鉀、甜菊糖苷或兩者以上之組合。本創作之酸味劑包括但不限於檸檬酸、檸檬酸鈉、檸檬酸三鈉、己二酸、丁二酸、丁二酸單鈉乳酸、乳酸鈉、蘋果酸、蘋果酸鈉、磷酸、酒石酸、酒石酸鈉、葡萄糖酸、葡萄糖酸鉀、葡萄糖酸鈉、乙酸、冰乙酸或胺基乙酸。於本創作之一具體實施例中, 該保護層另包含甜味劑、酸味劑或其組合,較佳地,該甜味劑為天然植物來源所獲得之糖漿、萃取物、濃縮物或香料、糖醇類甜味劑或其組合;更佳地,該甜味劑為羅漢果萃取物、甜菊糖苷、蔗糖素、醋磺內酯鉀或其中兩者以上之組合。於本創作之一具體實施例中,該保護層具有釋放該調味劑之作用,例如該保護層於液體中崩解、分解或溶解,以釋放該調味劑。於本創作之一具體實施例中,該液體為飲用水。 The term "flavoring agent" as used herein refers to natural, synthetic or semi-synthetic substances on food or physiologically acceptable, which induce taste, smell, touch and other sensations in the body of the eater, among them, induce sweetness in the body of the eater Those that induce sour taste in the body of the eater are called "sweeteners". Sweeteners in this invention include but are not limited to juices, powders, syrups, extracts, concentrates or flavors obtained from natural plant sources such as: chocolate, lemon, strawberry, banana, berry, mango, cantaloupe , passion fruit, pineapple, peach, cherry, cinnamon, apple, fennel, honey, pear, maple syrup, grape, grapefruit, orange, tangerine, watermelon, monk fruit, mushroom, or vanilla; sugar sweeteners including, but not Limited to lactose, galactooligosaccharides, sucrose, fructose, maltose, glucose or granulated sugar; sugar alcohol sweeteners include but not limited to xylitol, mannitol, sorbitol, erythritol, isomaltulose alcohol, steviol glycoside, erythritol, or lactitol; and artificial sweeteners including, but not limited to, aspartame or its derivatives, acesulfame potassium, neohesperidin dihydrochalcone, liquiritigenin, Acesulfame potassium or sucralose. In a specific embodiment of the invention, the sweetener is Luo Han Guo extract, steviol glycoside, mushroom extract or a combination of two or more thereof. In another specific embodiment, the sweetener is Luo Han Guo extract, sucralose, acesulfame potassium, steviol glycoside or a combination of the two or more. Sour agents in this creation include but are not limited to citric acid, sodium citrate, trisodium citrate, adipic acid, succinic acid, monosodium succinate lactic acid, sodium lactate, malic acid, sodium malate, phosphoric acid, tartaric acid, tartaric acid Sodium, gluconic acid, potassium gluconate, sodium gluconate, acetic acid, glacial acetic acid, or glycine. In one specific embodiment of this creation, The protective layer further comprises a sweetener, a sour agent or a combination thereof, preferably, the sweetener is a syrup, extract, concentrate or spice obtained from a natural plant source, a sugar alcohol sweetener or a combination thereof; More preferably, the sweetener is Luo Han Guo extract, steviol glycoside, sucralose, acesulfame potassium or a combination of two or more thereof. In a specific embodiment of the present invention, the protective layer has the effect of releasing the flavoring agent, for example, the protective layer disintegrates, decomposes or dissolves in the liquid to release the flavoring agent. In one embodiment of the invention, the liquid is drinking water.
於本創作之一具體實施例中,該保護層無添加抗結塊劑。 In one embodiment of the present invention, no anti-caking agent is added to the protective layer.
於本創作之一具體實施例中,該保護層之厚度為0.01mm至0.02mm、0.03mm至0.05mm、或0.015mm至0.025mm。 In a specific embodiment of the present invention, the protective layer has a thickness of 0.01mm to 0.02mm, 0.03mm to 0.05mm, or 0.015mm to 0.025mm.
於本創作之一具體實施例中,該顆粒結構包含65.5%至90.8%之功能性成分。較佳地,該顆粒結構包含10%至30%之含紅茶菌菇發酵液。於本創作之一具體實施例中,該顆粒結構包含1%至10%之紅茶粉。較佳地,該顆粒結構包含50%至70%之纖維。更佳地,該顆粒結構包含20%至30%之紅茶菌菇發酵液、3%至8%之紅茶粉及60%至70%之纖維。 In one embodiment of the present invention, the granular structure contains 65.5% to 90.8% functional ingredients. Preferably, the granular structure contains 10% to 30% of the kombucha mushroom-containing fermentation liquid. In one embodiment of the present invention, the granular structure contains 1% to 10% black tea powder. Preferably, the granular structure comprises 50% to 70% fibers. More preferably, the granular structure comprises 20% to 30% of kombucha fermented liquid, 3% to 8% of black tea powder and 60% to 70% of fiber.
於本創作之一具體實施例中,係使用流動床噴霧造粒製程將該功能性成分與該載劑或該賦形劑混合,以達到快速且均勻混合之目的。 In one embodiment of the present invention, fluidized bed spray granulation process is used to mix the functional ingredient with the carrier or the excipient to achieve rapid and uniform mixing.
以下係藉由具體的製備例及實施例進一步說明本創作之特點及其功效,但非用於限制本創作之範圍。 The following is to further illustrate the characteristics and effects of this creation by means of specific preparation examples and examples, but it is not intended to limit the scope of this creation.
製備例Preparation example
圖1顯示製備本創作之顆粒結構的方法,其包含下列步驟: Fig. 1 shows the method for preparing the granular structure of the present invention, which comprises the following steps:
步驟(a):將玉米來源可溶性纖維、即溶紅茶粉、菊苣纖維等功能性成分進行過篩; Step (a): sieving functional ingredients such as corn-derived soluble fiber, instant black tea powder, and chicory fiber;
步驟(b):將過篩後之成分以流動床乾燥設備進行57℃至63℃混合及乾燥; Step (b): Mix and dry the sieved ingredients at a temperature of 57°C to 63°C with fluidized bed drying equipment;
步驟(c):將混合及乾燥後之成分進行噴霧造粒程序以形成核心,其過程中可視需要加入水、食用香料、甜味劑、酸味劑、膠體或其中兩者以上之組合; Step (c): subjecting the mixed and dried ingredients to spray granulation to form a core, during which water, flavoring, sweetener, sour agent, colloid or a combination of two or more thereof may be added;
步驟(d):加入水、食用香料、甜味劑、酸味劑、膠體或其中兩者以上之組合,以形成包覆核心之調味殼層; Step (d): adding water, food flavoring agent, sweetener, sour agent, colloid or a combination of two or more thereof to form a seasoning shell covering the core;
步驟(e):依序添加紅茶菌發酵液成分、香氣之微膠囊及抗吸濕之膠體組合成分針對顆粒結構進行乾燥; Step (e): sequentially add kombucha fermented liquid components, aroma microcapsules and anti-hygroscopic colloid components to dry the granular structure;
步驟(f):針對顆粒結構進行整粒,以達到所需之平均粒徑及形狀。 Step (f): Sizing the particle structure to achieve the required average particle size and shape.
實施例1:顆粒結構之剖面Example 1: Cross section of granular structure
如圖2所示,本創作之顆粒結構100包含紅茶粉11、纖維12、紅茶菌菇發酵液13、調味殼層22及保護層23,其中,該調味殼層22包含香氣微膠囊21。
As shown in FIG. 2 , the
實施例2:噴霧造粒溫度對有機酸保留之影響Embodiment 2: The influence of spray granulation temperature on organic acid retention
以上述製備例所述方法,於37℃至43℃、57℃至63℃、77℃至83℃之噴霧造粒溫度範圍下,分別製備顆粒結構之實例A及實例A’、實例B及實例B’、實例C,並於製備完成時及常溫儲藏1個月後測定每克實例中的醋酸含量(毫克),結果如下表1及表2所示: Using the method described in the above preparation example, under the spray granulation temperature range of 37°C to 43°C, 57°C to 63°C, and 77°C to 83°C, respectively prepare the example A, example A', example B and example of the granule structure B', example C, and measure the acetic acid content (mg) in every gram example when preparation is completed and storage at normal temperature after 1 month, the results are shown in Table 1 and Table 2 below:
上表1顯示於顆粒結構製備完成時,實例B之醋酸含量高於實例A及實例C。上表2則顯示經常溫儲藏1個月後,實例B’之醋酸耗損率低於實例A’。上述數據表示使用57℃至63℃之噴霧造粒溫度所形成的顆粒結構具有較佳的醋酸保留效果。 The above Table 1 shows that the acetic acid content of Example B is higher than that of Example A and Example C when the preparation of the granular structure is completed. The above table 2 shows that after 1 month storage at normal temperature, the consumption rate of acetic acid in Example B' is lower than that in Example A'. The above data indicate that the granule structure formed by using the spray granulation temperature of 57°C to 63°C has a better acetic acid retention effect.
實施例3:流動性測試 Embodiment 3: fluidity test
測定實施例2中的實例B與市售品之總體密度(bulk density)及振實密度(tapped density),再進一步計算其卡爾指數(Carr’s index)及豪斯納比(Hausner ratio),結果如下表3所示: Measure the overall density (bulk density) and tapped density (tapped density) of Example B in Example 2 and commercially available products, and then further calculate its Carr's index (Carr's index) and Hausner ratio (Hausner ratio), the results are as follows Table 3 shows:
*卡爾指數=[(振實密度-體密度)÷振實密度]×100% *Carr index=[(tap density-bulk density)÷tap density]×100%
*豪斯納比=振實密度÷體密度 *Hausner ratio = tap density ÷ bulk density
總體密度係指未經振實之顆粒樣品的質量與其總體積(包括顆粒間的空隙體積)之比值,一般而言,其值越低的產品,其顆粒粒徑較大,相對利於包裝、運輸和儲存。振實密度則是指對裝有顆粒樣品的容器振動以使顆粒處於緊密填充狀態後的密度。卡爾指數及豪斯納比為流動性指標,其值越低,表示顆粒樣品之流動性越高。由上表可知,實例B之總體密度、卡爾指數及豪斯納比皆小於市售品,表示本創作之成品相較於其它市售品具有較佳的流動性與充填適性,且更有利於包裝、運輸和儲存。 The overall density refers to the ratio of the mass of the unvibrated particle sample to its total volume (including the void volume between particles). Generally speaking, the lower the value, the larger the particle size, which is relatively convenient for packaging and transportation. and storage. Tapped density refers to the density after vibrating the container containing the particle sample so that the particles are in a tightly packed state. Carr index and Hausner ratio are fluidity indicators, and the lower the value, the higher the fluidity of the particle sample. It can be seen from the above table that the overall density, Carr index and Hausner ratio of Example B are all lower than those of commercially available products, indicating that the finished product of this creation has better fluidity and filling suitability than other commercially available products, and is more conducive to Packaging, shipping and storage.
上述製備例或實施例僅為例示性說明,而非用於限制本創作。本領域之通常知識者均可在不違背本創作之精神及範疇下,對上述實施例進行修飾與改變。因此,本創作之權利保護範圍係由所附之申請專利範圍所定義,只要不影響本創作之效果及實施目的,應涵蓋於此公開技術內容中。 The above-mentioned preparation examples or examples are only illustrative descriptions, not intended to limit the present invention. Those skilled in the art can modify and change the above-mentioned embodiments without departing from the spirit and scope of the invention. Therefore, the protection scope of the rights of this creation is defined by the scope of the attached patent application, as long as it does not affect the effect and implementation purpose of this creation, it should be covered in this disclosed technical content.
100:顆粒結構 100: Granular structure
11:紅茶粉 11: black tea powder
12:纖維 12: Fiber
13:紅茶菌菇發酵液 13: Kombucha fermented liquid
21:香氣微膠囊 21: Aroma microcapsules
22:調味殼層 22: Seasoned Shells
23:保護層 23: Protective layer
Claims (7)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TW111214643U TWM641394U (en) | 2022-12-30 | 2022-12-30 | Granular structure with active compound of organic acids |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TW111214643U TWM641394U (en) | 2022-12-30 | 2022-12-30 | Granular structure with active compound of organic acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TWM641394U true TWM641394U (en) | 2023-05-21 |
Family
ID=87382568
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW111214643U TWM641394U (en) | 2022-12-30 | 2022-12-30 | Granular structure with active compound of organic acids |
Country Status (1)
| Country | Link |
|---|---|
| TW (1) | TWM641394U (en) |
-
2022
- 2022-12-30 TW TW111214643U patent/TWM641394U/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP5826107B2 (en) | Composition for enteral administration of microorganisms | |
| US20120015075A1 (en) | Chewable supplement with live microorganisms | |
| WO2001083704A1 (en) | Spray-dried microbial cells | |
| CN114698849A (en) | A kind of probiotic composition and its preparation method and application | |
| CN103347398A (en) | Soluble milk-based tablet surface-treated with carbohydrate | |
| JP2023552860A (en) | Improving protein digestion and amino acid bioavailability with probiotic strains | |
| CN103180432A (en) | Process of producing shelf stable probiotic food | |
| TWM605965U (en) | Granular structure for encapsulating probiotics | |
| JP2023552861A (en) | Bioprocessing of proteins using probiotic bacteria to improve amino acids and | |
| US20180228179A1 (en) | Glycerin-based gummy candy and foam candy products with probiotic bacteria | |
| JP6945888B1 (en) | Composition for improving immune function | |
| TWI868553B (en) | Granular structure with active compound of organic acids and method for preparing the same | |
| TWM641394U (en) | Granular structure with active compound of organic acids | |
| KR102535339B1 (en) | Glycerin-based and protein-based foamed candy products with probiotic bacteria | |
| JP2004097114A (en) | Dried product of jelly | |
| JP2612001B2 (en) | Granules containing useful intestinal bacteria and method for producing the same | |
| CN103997900A (en) | Soluble non-dairy creamer tablet surface-treated with carbohydrate | |
| Kandur et al. | Oral pharmabiotic tablet formulations | |
| CN109259245A (en) | A kind of the probiotics Intestine-lubricatinhealth-care health-care food and preparation method stable by fiber | |
| CN105724571B (en) | Isotonic probiotics preparation and preparation method thereof | |
| CN213549547U (en) | Probiotics particle with core-shell structure and probiotics soft capsule | |
| CN117256765A (en) | Composition containing white kidney bean extract and preparation method and application thereof | |
| CN116369528A (en) | Probiotic flavor crystal ball formula | |
| JP7440144B1 (en) | Oral composition | |
| Şenöztop et al. | A comprehensive review on the development of probiotic supplemented confectioneries |