TWI738753B - 雜環化合物 - Google Patents

Info

Publication number

TWI738753B

TWI738753B TW106110783A TW106110783A TWI738753B TW I738753 B TWI738753 B TW I738753B TW 106110783 A TW106110783 A TW 106110783A TW 106110783 A TW106110783 A TW 106110783A TW I738753 B TWI738753 B TW I738753B

Authority

TW

Taiwan

Prior art keywords

group

substituted

compound

ring

optionally

Prior art date

2016-03-31

Links

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• 150000002391 heterocyclic compounds Chemical class 0.000 title description 4
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• 125000001424 substituent group Chemical group 0.000 claims description 201
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• 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims description 72
• 125000000217 alkyl group Chemical group 0.000 claims description 58
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• 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 29
• 125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 claims description 27
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 26
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• 125000006376 (C3-C10) cycloalkyl group Chemical group 0.000 claims description 25
• 125000002393 azetidinyl group Chemical group 0.000 claims description 25
• 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 25
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• 230000036506 anxiety Effects 0.000 claims description 16
• QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 claims description 16
• BSQKGAVROUDOTE-UHFFFAOYSA-N 7-azaspiro[3.5]nonane Chemical group C1CCC21CCNCC2 BSQKGAVROUDOTE-UHFFFAOYSA-N 0.000 claims description 14
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• 239000000706 filtrate Substances 0.000 description 24
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• NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 description 20
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