TWI331535B - Antimicrobial lenses displaying extended efficacy, processes to prepare them and methods of their use - Google Patents

Antimicrobial lenses displaying extended efficacy, processes to prepare them and methods of their use Download PDF

Info

Publication number: TWI331535B
Authority: TW; Taiwan
Prior art keywords: silver; lens; contact lens; eye; lenses
Prior art date: 2002-11-22

Application number

TW92132886A

Other languages

English (en)

Chinese (zh)

Other versions

TW200505510A (en

Inventor

Osman Rathore

Diana Zanini

Frank Neely

Donald E Riederer

Ann-Margret Andersson

Douglas Vanderlaan

Original Assignee

Johnson & Johnson Vision Care

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-11-22

Filing date

2003-11-24

Publication date

2010-10-11

2003-11-24 Application filed by Johnson & Johnson Vision Care filed Critical Johnson & Johnson Vision Care

2005-02-16 Publication of TW200505510A publication Critical patent/TW200505510A/zh

2010-10-11 Application granted granted Critical

2010-10-11 Publication of TWI331535B publication Critical patent/TWI331535B/zh

Links

238000000034 method Methods 0.000 title description 38
230000000845 anti-microbial effect Effects 0.000 title description 18
230000008569 process Effects 0.000 title description 5
229910052709 silver Inorganic materials 0.000 claims description 166
239000004332 silver Substances 0.000 claims description 165
BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 claims description 153
150000001875 compounds Chemical class 0.000 claims description 47
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 44
-1 silver halide Chemical class 0.000 claims description 37
229910001868 water Inorganic materials 0.000 claims description 21
230000000813 microbial effect Effects 0.000 claims description 18
230000009467 reduction Effects 0.000 claims description 15
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FOIXSVOLVBLSDH-UHFFFAOYSA-N Silver ion Chemical compound [Ag+] FOIXSVOLVBLSDH-UHFFFAOYSA-N 0.000 claims description 10
RJGDLRCDCYRQOQ-UHFFFAOYSA-N anthrone Chemical compound C1=CC=C2C(=O)C3=CC=CC=C3CC2=C1 RJGDLRCDCYRQOQ-UHFFFAOYSA-N 0.000 claims description 9
230000002079 cooperative effect Effects 0.000 claims description 9
239000011541 reaction mixture Substances 0.000 claims description 8
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UURVHRGPGCBHIC-UHFFFAOYSA-N 3-(ethenoxycarbonylamino)propanoic acid 4-[[[[[[[[[[[[[[[[[[[[[[[[[[[4-ethenoxycarbonyloxybutyl(dimethyl)silyl]oxy-dimethylsilyl]oxy-dimethylsilyl]oxy-dimethylsilyl]oxy-dimethylsilyl]oxy-dimethylsilyl]oxy-dimethylsilyl]oxy-dimethylsilyl]oxy-dimethylsilyl]oxy-dimethylsilyl]oxy-dimethylsilyl]oxy-dimethylsilyl]oxy-dimethylsilyl]oxy-dimethylsilyl]oxy-dimethylsilyl]oxy-dimethylsilyl]oxy-dimethylsilyl]oxy-dimethylsilyl]oxy-dimethylsilyl]oxy-dimethylsilyl]oxy-dimethylsilyl]oxy-dimethylsilyl]oxy-dimethylsilyl]oxy-dimethylsilyl]oxy-dimethylsilyl]oxy-dimethylsilyl]oxy-dimethylsilyl]butyl ethenyl carbonate 1-ethenylpyrrolidin-2-one ethenyl N-[3-tris(trimethylsilyloxy)silylpropyl]carbamate Chemical compound C=CN1CCCC1=O.OC(=O)CCNC(=O)OC=C.C[Si](C)(C)O[Si](CCCNC(=O)OC=C)(O[Si](C)(C)C)O[Si](C)(C)C.C[Si](C)(CCCCOC(=O)OC=C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)CCCCOC(=O)OC=C UURVHRGPGCBHIC-UHFFFAOYSA-N 0.000 claims description 3
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229920002521 macromolecule Polymers 0.000 description 10
IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 9
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102100026735 Coagulation factor VIII Human genes 0.000 description 7
101000911390 Homo sapiens Coagulation factor VIII Proteins 0.000 description 7
WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical compound CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 description 7
238000004458 analytical method Methods 0.000 description 7
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239000008367 deionised water Substances 0.000 description 7
229910021641 deionized water Inorganic materials 0.000 description 7
238000004519 manufacturing process Methods 0.000 description 7
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XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 6
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239000003085 diluting agent Substances 0.000 description 6
FVAUCKIRQBBSSJ-UHFFFAOYSA-M sodium iodide Chemical compound [Na+].[I-] FVAUCKIRQBBSSJ-UHFFFAOYSA-M 0.000 description 6
229910021612 Silver iodide Inorganic materials 0.000 description 5
239000007864 aqueous solution Substances 0.000 description 5
238000004140 cleaning Methods 0.000 description 5
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125000005207 tetraalkylammonium group Chemical group 0.000 description 5
CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 4
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239000011248 coating agent Substances 0.000 description 4
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YLQWCDOCJODRMT-UHFFFAOYSA-N fluoren-9-one Chemical compound C1=CC=C2C(=O)C3=CC=CC=C3C2=C1 YLQWCDOCJODRMT-UHFFFAOYSA-N 0.000 description 4
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UYIGYAUAISULQS-UHFFFAOYSA-M silver;2-sulfanylbenzoate Chemical compound [Ag+].[O-]C(=O)C1=CC=CC=C1S UYIGYAUAISULQS-UHFFFAOYSA-M 0.000 description 4
ZXSQEZNORDWBGZ-UHFFFAOYSA-N 1,3-dihydropyrrolo[2,3-b]pyridin-2-one Chemical group C1=CN=C2NC(=O)CC2=C1 ZXSQEZNORDWBGZ-UHFFFAOYSA-N 0.000 description 3
HWSSEYVMGDIFMH-UHFFFAOYSA-N 2-[2-[2-(2-methylprop-2-enoyloxy)ethoxy]ethoxy]ethyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCCOCCOCCOC(=O)C(C)=C HWSSEYVMGDIFMH-UHFFFAOYSA-N 0.000 description 3
JKFYKCYQEWQPTM-UHFFFAOYSA-N 2-azaniumyl-2-(4-fluorophenyl)acetate Chemical compound OC(=O)C(N)C1=CC=C(F)C=C1 JKFYKCYQEWQPTM-UHFFFAOYSA-N 0.000 description 3
ZOPSJJCUEOEROC-NSQCPRBHSA-N 3-[[butyl(dimethyl)silyl]oxy-dimethylsilyl]propyl 2-methylprop-2-enoate;n,n-dimethylprop-2-enamide;1-ethenylpyrrolidin-2-one;2-hydroxyethyl 2-methylprop-2-enoate;[(2r)-2-hydroxy-3-[3-[methyl-bis(trimethylsilyloxy)silyl]propoxy]propyl] 2-methylprop-2-enoat Chemical compound CN(C)C(=O)C=C.C=CN1CCCC1=O.CC(=C)C(=O)OCCO.CC(=C)C(=O)OCCOC(=O)C(C)=C.CCCC[Si](C)(C)O[Si](C)(C)CCCOC(=O)C(C)=C.CC(=C)C(=O)OC[C@H](O)COCCC[Si](C)(O[Si](C)(C)C)O[Si](C)(C)C ZOPSJJCUEOEROC-NSQCPRBHSA-N 0.000 description 3
BTBUEUYNUDRHOZ-UHFFFAOYSA-N Borate Chemical compound [O-]B([O-])[O-] BTBUEUYNUDRHOZ-UHFFFAOYSA-N 0.000 description 3
241000124008 Mammalia Species 0.000 description 3
ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical compound CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 description 3
239000007983 Tris buffer Substances 0.000 description 3
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229910021645 metal ion Inorganic materials 0.000 description 3
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VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 3
DIOQZVSQGTUSAI-UHFFFAOYSA-N n-butylhexane Natural products CCCCCCCCCC DIOQZVSQGTUSAI-UHFFFAOYSA-N 0.000 description 3
238000004806 packaging method and process Methods 0.000 description 3
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229910001958 silver carbonate Inorganic materials 0.000 description 3
LKZMBDSASOBTPN-UHFFFAOYSA-L silver carbonate Substances [Ag].[O-]C([O-])=O LKZMBDSASOBTPN-UHFFFAOYSA-L 0.000 description 3
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150000003379 silver compounds Chemical class 0.000 description 3
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NDVLTYZPCACLMA-UHFFFAOYSA-N silver oxide Substances [O-2].[Ag+].[Ag+] NDVLTYZPCACLMA-UHFFFAOYSA-N 0.000 description 3
NLAIHECABDOZBR-UHFFFAOYSA-M sodium 2,2-bis(2-methylprop-2-enoyloxymethyl)butyl 2-methylprop-2-enoate 2-hydroxyethyl 2-methylprop-2-enoate 2-methylprop-2-enoate Chemical compound [Na+].CC(=C)C([O-])=O.CC(=C)C(=O)OCCO.CCC(COC(=O)C(C)=C)(COC(=O)C(C)=C)COC(=O)C(C)=C NLAIHECABDOZBR-UHFFFAOYSA-M 0.000 description 3
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NRSOIGBFZHRBDM-UHFFFAOYSA-N 2-aminobenzenethiol;silver Chemical compound [Ag].NC1=CC=CC=C1S NRSOIGBFZHRBDM-UHFFFAOYSA-N 0.000 description 2
KFDVPJUYSDEJTH-UHFFFAOYSA-N 4-ethenylpyridine Chemical compound C=CC1=CC=NC=C1 KFDVPJUYSDEJTH-UHFFFAOYSA-N 0.000 description 2
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OTUQZYKBLAIJGU-UHFFFAOYSA-N benzenethiol;silver Chemical compound [Ag].SC1=CC=CC=C1 OTUQZYKBLAIJGU-UHFFFAOYSA-N 0.000 description 2
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LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 description 2
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RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Substances C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 description 2
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MHOVAHRLVXNVSD-UHFFFAOYSA-N rhodium atom Chemical compound [Rh] MHOVAHRLVXNVSD-UHFFFAOYSA-N 0.000 description 1
229940009188 silver Drugs 0.000 description 1
ADZWSOLPGZMUMY-UHFFFAOYSA-M silver bromide Chemical compound [Ag]Br ADZWSOLPGZMUMY-UHFFFAOYSA-M 0.000 description 1
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BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 1
239000006228 supernatant Substances 0.000 description 1
JRMUNVKIHCOMHV-UHFFFAOYSA-M tetrabutylammonium bromide Chemical compound [Br-].CCCC[N+](CCCC)(CCCC)CCCC JRMUNVKIHCOMHV-UHFFFAOYSA-M 0.000 description 1
TXEYQDLBPFQVAA-UHFFFAOYSA-N tetrafluoromethane Chemical compound FC(F)(F)F TXEYQDLBPFQVAA-UHFFFAOYSA-N 0.000 description 1
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ZUZPOSNHFCUOMQ-UHFFFAOYSA-N thiolan-2-amine Chemical compound NC1CCCS1 ZUZPOSNHFCUOMQ-UHFFFAOYSA-N 0.000 description 1
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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
- A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
- A61L12/088—Heavy metals
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
- G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
- G02B1/041—Lenses
- G02B1/043—Contact lenses

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Health & Medical Sciences (AREA)
Physics & Mathematics (AREA)
General Physics & Mathematics (AREA)
Optics & Photonics (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Apparatus For Disinfection Or Sterilisation (AREA)
Ophthalmology & Optometry (AREA)
Eyeglasses (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

TW92132886A 2002-11-22 2003-11-24 Antimicrobial lenses displaying extended efficacy, processes to prepare them and methods of their use TWI331535B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US42862002P	2002-11-22	2002-11-22

Publications (2)

Publication Number	Publication Date
TW200505510A TW200505510A (en)	2005-02-16
TWI331535B true TWI331535B (en)	2010-10-11

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TW92132886A TWI331535B (en)	2002-11-22	2003-11-24	Antimicrobial lenses displaying extended efficacy, processes to prepare them and methods of their use
TW092132888A TWI341405B (en)	2002-11-22	2003-11-24	Antimicrobial lenses, processes to prepare them and methods of their use

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TW092132888A TWI341405B (en)	2002-11-22	2003-11-24	Antimicrobial lenses, processes to prepare them and methods of their use

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KR (1)	KR20060039391A (es)
CN (1)	CN100408106C (es)
AR (3)	AR042122A1 (es)
TW (2)	TWI331535B (es)
WO (1)	WO2004047878A1 (es)

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Publication number	Priority date	Publication date	Assignee	Title
US20030044447A1 (en) *	2000-12-21	2003-03-06	Diana Zanini	Antimicrobial contact lenses and methods for their production
US8425926B2 (en) *	2003-07-16	2013-04-23	Yongxing Qiu	Antimicrobial medical devices
US7335613B2 (en) *	2004-04-08	2008-02-26	Rohm And Haas Company	Fiber substrate with antibacterial finish and methods of making and using the same
US7390774B2 (en)	2004-04-08	2008-06-24	Rohm And Haas Company	Antibacterial composition and methods of making and using the same
US20060142525A1 (en) *	2004-12-29	2006-06-29	Bausch & Lomb Incorporated	Hydrogel copolymers for biomedical devices
AU2006222708A1 (en) *	2005-10-07	2007-04-26	Rohm And Haas Company	Method for disinfecting or sanitizing a surface
AU2014210607B2 (en) *	2006-10-31	2015-04-30	Johnson & Johnson Vision Care, Inc.	Antimicrobial polymeric articles, processes to prepare them and methods of their use
US20080102122A1 (en) *	2006-10-31	2008-05-01	Shivkumar Mahadevan	Antimicrobial polymeric articles, processes to prepare them and methods of their use
US20080102095A1 (en) *	2006-10-31	2008-05-01	Kent Young	Acidic processes to prepare antimicrobial contact lenses
KR20090101894A (ko) *	2006-10-31	2009-09-29	존슨 앤드 존슨 비젼 케어, 인코포레이티드	항균 콘택트 렌즈의 제조방법
AU2012261717B2 (en) *	2006-10-31	2014-09-04	Johnson & Johnson Vision Care, Inc.	Antimicrobial polymeric articles, processes to prepare them and methods of their use
US20080100797A1 (en) *	2006-10-31	2008-05-01	Nayiby Alvarez-Carrigan	Antimicrobial contact lenses with reduced haze and preparation thereof
US20080241225A1 (en) *	2007-03-31	2008-10-02	Hill Gregory A	Basic processes to prepare antimicrobial contact lenses
US20090092538A1 (en) *	2007-10-08	2009-04-09	Amit Khanolkar	Methods for forming stabilized metal salt particles
RU2621301C1 (ru) *	2016-03-24	2017-06-01	Федеральное государственное бюджетное образовательное учреждение высшего образования "Волгоградский государственный технический университет" (ВолгГТУ)	Способ получения высокодисперсных стабилизированных частиц йодида серебра в водных растворах
DE102018126842B4 (de) *	2018-10-26	2020-10-15	Carl Zeiss Meditec Ag	Ophthalmologisches Implantat, Verfahren zum Herstellen eines ophthalmologischen Implantats und Verwendung eines Liganden zur Herstellung eines ophthalmologischen Implantats

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Publication number	Priority date	Publication date	Assignee	Title
DE10024363A1 (de) *	2000-05-17	2001-11-29	Woehlk Contact Linsen Gmbh	Silberimprägnierte Kontaktlinse
US20030044447A1 (en) *	2000-12-21	2003-03-06	Diana Zanini	Antimicrobial contact lenses and methods for their production

2003
- 2003-11-21 CN CNB2003801091493A patent/CN100408106C/zh not_active Expired - Fee Related
- 2003-11-21 WO PCT/US2003/037368 patent/WO2004047878A1/en not_active Ceased
- 2003-11-21 AR ARP030104316 patent/AR042122A1/es unknown
- 2003-11-21 KR KR1020057009221A patent/KR20060039391A/ko not_active Ceased
- 2003-11-24 TW TW92132886A patent/TWI331535B/zh not_active IP Right Cessation
- 2003-11-24 TW TW092132888A patent/TWI341405B/zh not_active IP Right Cessation
2009
- 2009-06-08 AR ARP090102057 patent/AR072076A2/es unknown
- 2009-06-08 AR ARP090102056 patent/AR072075A2/es unknown

Also Published As

Publication number	Publication date
AR072076A2 (es)	2010-08-04
TW200505510A (en)	2005-02-16
CN100408106C (zh)	2008-08-06
AR042122A1 (es)	2005-06-08
TW200504402A (en)	2005-02-01
KR20060039391A (ko)	2006-05-08
AR072075A2 (es)	2010-08-04
WO2004047878A1 (en)	2004-06-10
CN1741823A (zh)	2006-03-01
TWI341405B (en)	2011-05-01

Publication	Publication Date	Title
TWI331535B (en)	2010-10-11	Antimicrobial lenses displaying extended efficacy, processes to prepare them and methods of their use
CN100522255C (zh)	2009-08-05	抗菌透镜及其制备方法
TWI444700B (zh)	2014-07-11	抗菌鏡片，其製法及使用方法
TWI409086B (zh)	2013-09-21	抗微生物之聚合物物件，其製法及使用方法
US20040150788A1 (en)	2004-08-05	Antimicrobial lenses, processes to prepare them and methods of their use
EP1355681B1 (en)	2006-03-08	Antimicrobial contact lenses containing activated silver and methods for their production
US20030044447A1 (en)	2003-03-06	Antimicrobial contact lenses and methods for their production
AU2002246868A1 (en)	2003-05-29	Antimicrobial lenses and methods of their use
US20040151755A1 (en)	2004-08-05	Antimicrobial lenses displaying extended efficacy, processes to prepare them and methods of their use
AU2007333480B2 (en)	2013-07-25	Processes to prepare antimicrobial contact lenses
US20130109778A1 (en)	2013-05-02	Preparation of antimicrobial contact lenses with reduced haze using swelling agents
TW200836777A (en)	2008-09-16	Antimicrobial contact lenses with reduced haze and preparation thereof
EP1769809A2 (en)	2007-04-04	Antimicrobial lenses displaying extended efficacy, processes to prepare them and methods of their use
HK1102566A (en)	2007-11-30	Antimicrobial lenses displaying extended efficacy, processes to prepare them and methods of their use
HK1100485A (en)	2007-09-21	Antimicrobial lenses displaying extended efficacy, process to prepare them and methods of their use
AU2002246869A1 (en)	2002-08-19	Antimicrobial contact lenses containing activated silver and methods for their production
HK1056516B (en)	2006-09-08	Antimicrobial contact lenses containing activated silver and methods for their production
HK1162981A (en)	2012-09-07	Antimicrobial lenses, processes to prepare them and methods of their use
HK1162980A (en)	2012-09-07	Antimicrobial lenses, processes to prepare them and methods of their use
HK1138216A (en)	2010-08-20	Acidic processes to prepare antimicrobial contact lenses
HK1138217A (en)	2010-08-20	Processes to prepare antimicrobial contact lenses

Legal Events

Date	Code	Title	Description
2021-07-11	MM4A	Annulment or lapse of patent due to non-payment of fees