[go: up one dir, main page]

TW200942529A - Pyrrolidinyl derivatives and uses thereof - Google Patents

Pyrrolidinyl derivatives and uses thereof

Info

Publication number
TW200942529A
TW200942529A TW098108642A TW98108642A TW200942529A TW 200942529 A TW200942529 A TW 200942529A TW 098108642 A TW098108642 A TW 098108642A TW 98108642 A TW98108642 A TW 98108642A TW 200942529 A TW200942529 A TW 200942529A
Authority
TW
Taiwan
Prior art keywords
compounds
methods
pyrrolidinyl derivatives
pyrrolidinyl
derivatives
Prior art date
Application number
TW098108642A
Other languages
English (en)
Inventor
Matthew C Lucas
Ryan Craig Schoenfeld
Robert James Weikert
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of TW200942529A publication Critical patent/TW200942529A/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
TW098108642A 2008-03-20 2009-03-17 Pyrrolidinyl derivatives and uses thereof TW200942529A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3816008P 2008-03-20 2008-03-20

Publications (1)

Publication Number Publication Date
TW200942529A true TW200942529A (en) 2009-10-16

Family

ID=40651460

Family Applications (1)

Application Number Title Priority Date Filing Date
TW098108642A TW200942529A (en) 2008-03-20 2009-03-17 Pyrrolidinyl derivatives and uses thereof

Country Status (17)

Country Link
US (1) US20110021556A1 (zh)
EP (1) EP2257545B1 (zh)
JP (1) JP2011515355A (zh)
KR (1) KR101209373B1 (zh)
CN (1) CN101977907A (zh)
AR (1) AR070930A1 (zh)
AT (1) ATE522519T1 (zh)
AU (1) AU2009226868A1 (zh)
BR (1) BRPI0909737A2 (zh)
CA (1) CA2718736A1 (zh)
CL (1) CL2009000665A1 (zh)
ES (1) ES2370593T3 (zh)
IL (1) IL207223A0 (zh)
MX (1) MX2010009147A (zh)
PE (1) PE20091649A1 (zh)
TW (1) TW200942529A (zh)
WO (1) WO2009115427A1 (zh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013538800A (ja) * 2010-08-10 2013-10-17 アッヴィ・インコーポレイテッド 新規trpv3モジュレーター
US8889730B2 (en) 2012-04-10 2014-11-18 Pfizer Inc. Indole and indazole compounds that activate AMPK
CA2905242C (en) 2013-03-15 2016-11-29 Pfizer Inc. Indole compounds that activate ampk
CN110662541B (zh) * 2017-03-12 2023-02-10 王晓冬 多环胺作为阿片受体调节剂
US11584765B2 (en) 2017-03-12 2023-02-21 Ecstasy LLC Polycyclic amines as sigma receptor modulators
CA3187566A1 (en) 2020-06-22 2021-12-30 Corcept Therapeutics Incorporated Quaternary indazole glucocorticoid receptor antagonists
JP7680053B2 (ja) * 2020-07-01 2025-05-20 エクスタシー・リミテッド・ライアビリティ・カンパニー オピオイド受容体変調のための多環式アミン
KR20240137134A (ko) 2021-12-21 2024-09-19 코어셉트 쎄라퓨틱스 인코포레이티드 피페라진 인다졸 글루코코르티코이드 수용체 길항제
JP2025501553A (ja) 2021-12-21 2025-01-22 コーセプト セラピューティクス, インコーポレイテッド 二環式インダゾールグルココルチコイド受容体拮抗薬
CN117285452A (zh) * 2023-09-19 2023-12-26 苏州雄鹰笔墨新材料有限公司 一种取代琥珀酰亚胺及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE374750T1 (de) * 2000-07-18 2007-10-15 Dainippon Sumitomo Pharma Co Serotoninwiederaufnahme-inhibitoren
TWI410406B (zh) * 2005-05-13 2013-10-01 Otsuka Pharma Co Ltd 吡咯烷化合物
PT2354124E (pt) * 2006-12-19 2013-04-09 Hoffmann La Roche Derivados de heteroaril-pirrolidinilo e piperidinil-cetona

Also Published As

Publication number Publication date
ATE522519T1 (de) 2011-09-15
US20110021556A1 (en) 2011-01-27
AR070930A1 (es) 2010-05-12
PE20091649A1 (es) 2009-11-04
KR20100118601A (ko) 2010-11-05
MX2010009147A (es) 2010-09-07
BRPI0909737A2 (pt) 2019-03-06
CA2718736A1 (en) 2009-09-24
KR101209373B1 (ko) 2012-12-06
IL207223A0 (en) 2010-12-30
CL2009000665A1 (es) 2010-04-09
EP2257545B1 (en) 2011-08-31
EP2257545A1 (en) 2010-12-08
CN101977907A (zh) 2011-02-16
ES2370593T3 (es) 2011-12-20
WO2009115427A1 (en) 2009-09-24
JP2011515355A (ja) 2011-05-19
AU2009226868A1 (en) 2009-09-24

Similar Documents

Publication Publication Date Title
TW200942529A (en) Pyrrolidinyl derivatives and uses thereof
MX2010003155A (es) Derivados de ciclopropil aril amida y uso de los mismos.
TW200726753A (en) 2,4-diamino-pyrimidines as aurora inhibitors
PH12013500745A1 (en) Azaadamantane derivatives and methods of use
MX2010006799A (es) Benzofuropirimidinonas como inhibidores de la proteina cinasa.
MX2010001754A (es) Derivados de azepina como inhibidores de gamma secretasa.
UA95644C2 (ru) Пиридазиноновые производные, фармацевтическая композиция и способ лечения заболеваний
MY148429A (en) Novel 1,4-benzothiepin-1,1-dioxide derivatives which are substituted with benzyl groups, method for producing drugs containing said compounds and use thereof
MX2010003156A (es) Derivados de aril amida substituida con tetrazol y usos de los mismos.
WO2007131072A3 (en) Hydrolytically-resistant boron-containing therapeutics and methods of use
UA102251C2 (ru) Производные аминодигидротиазина как ингибиторы васе для лечения болезни альцгеймера
MX2009009238A (es) Nuevos inhibidores de fosfodiesterasa.
MX350810B (es) Derivados de los nucleosidos sustituidos en 4 '-azido, 3 '-fluoro como inhibidores de la replicacion del rna del vhc.
MX2010009022A (es) Derivados 16 alfa, 17 alfa-acetal glucocorticoesteroideos y su uso.
TN2010000038A1 (en) Organic compounds
JO2682B1 (en) Derivatives of alkynil-8.1-naphthayridone, preparations thereof and therapeutic use thereof
UA99787C2 (en) Lactams as beta secretase inhibitors
TW200626553A (en) Novel compounds
MX2010009756A (es) Agonistas de receptores muscarinicos, composiciones, metodos de tratamiento de los mismos, y proceso para preparacion de los mismos.
UA101162C2 (ru) Производные индол-2-она, двузамещенные в положении 3, их получение и применение в терапии
TW200639156A (en) New compounds
MY144050A (en) Tetralin and indane derivatives and uses thereof
MX2010009837A (es) Tiazolil-dihidro-indazoles.
MX2007007027A (es) Derivados piperazinilpiridina como agentes anti-obesidad.
MY156955A (en) Antifungal agents