TR200201797T1 - Anti-hepaptit B ilacının direncinin saptanması - Google Patents
Anti-hepaptit B ilacının direncinin saptanmasıInfo
- Publication number
- TR200201797T1 TR200201797T1 TR2002/01797T TR200201797T TR200201797T1 TR 200201797 T1 TR200201797 T1 TR 200201797T1 TR 2002/01797 T TR2002/01797 T TR 2002/01797T TR 200201797 T TR200201797 T TR 200201797T TR 200201797 T1 TR200201797 T1 TR 200201797T1
- Authority
- TR
- Turkey
- Prior art keywords
- drug resistance
- detection
- hbv
- hepaptit
- patient
- Prior art date
Links
- 206010059866 Drug resistance Diseases 0.000 title abstract 3
- 238000001514 detection method Methods 0.000 title abstract 2
- 102000016928 DNA-directed DNA polymerase Human genes 0.000 abstract 2
- 108010014303 DNA-directed DNA polymerase Proteins 0.000 abstract 2
- 239000012472 biological sample Substances 0.000 abstract 1
- 230000002068 genetic effect Effects 0.000 abstract 1
- 238000003384 imaging method Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000035772 mutation Effects 0.000 abstract 1
- 239000000523 sample Substances 0.000 abstract 1
- 238000011896 sensitive detection Methods 0.000 abstract 1
- 238000011895 specific detection Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/706—Specific hybridization probes for hepatitis
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Communicable Diseases (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Bir mevcut bulus, bir hastadaki anti-HBV ilaci direncinin, bu hastadaki bir biyolojik örnekte bulunan HBV irklarinin DNA polimerazindaki L528M, M552V/I ve/veya V/L/M555I mutasyonlarindan en azindan birinin genetik saptanmasi sayesinde görüntülenmesi için olan bir metot ile ilgilidir. Mevcut bulus anti-HBV ilacinin direncinin çok belirgin ve duyarli bir saptanmasina olanak tasiyan yeni sondalarin tasarimi için kullanilan yeni HBV DNA polimeraz sekanslarini saglamaktadir.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99870148 | 1999-07-08 | ||
| US14354699P | 1999-07-13 | 1999-07-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200201797T1 true TR200201797T1 (tr) | 2003-05-21 |
Family
ID=30129296
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2002/01797T TR200201797T1 (tr) | 1999-07-08 | 2000-07-05 | Anti-hepaptit B ilacının direncinin saptanması |
| TR2001/00689T TR200100689T1 (tr) | 1999-07-08 | 2000-07-05 | Anti-hepatit B ilacının direncinin saptanması |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2001/00689T TR200100689T1 (tr) | 1999-07-08 | 2000-07-05 | Anti-hepatit B ilacının direncinin saptanması |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1144693A3 (tr) |
| JP (1) | JP2003505021A (tr) |
| CN (1) | CN1384888A (tr) |
| AR (1) | AR028149A1 (tr) |
| AU (1) | AU6431700A (tr) |
| BR (1) | BR0006899A (tr) |
| CA (1) | CA2339422A1 (tr) |
| TR (2) | TR200201797T1 (tr) |
| WO (1) | WO2001004358A2 (tr) |
| ZA (1) | ZA200101680B (tr) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6583279B1 (en) * | 2001-01-26 | 2003-06-24 | Becton, Dickinson And Company | Sequences and methods for detection of hepatitis B virus |
| GR1003878B (el) * | 2001-03-13 | 2002-04-24 | Γεωργακοπουλος Ελευθεριος Δρ. | Νεα μεθοδος ανιχνευσης και ταυτοποιησης σημειακων μεταλλαξεων στελεχων του ιου της ηπατιτιδος β (hbv) σε ορο αιματος ασθενων |
| CA2486420C (en) | 2002-06-14 | 2014-04-15 | Gen-Probe Incorporated | Compositions and methods for detecting hepatitis b virus |
| BR0314259A (pt) | 2002-09-13 | 2005-07-26 | Idenix Cayman Ltd | ß-l-2'-desoxinucleosìdeos para o tratamento de cepas de hbv resistentes e terapias combinadas |
| KR100650162B1 (ko) * | 2003-08-05 | 2006-11-27 | 주식회사 진인 | 품질 관리 프로브 및 음성 조절 프로브를 함유하는 약제내성 b형 간염 바이러스 검출용 마이크로어레이 및 이를이용한 약제 내성 b형 간염 바이러스의 검출 방법 |
| DK2094863T3 (da) * | 2006-12-18 | 2014-08-18 | Panagene Inc | Peptid-nukleinsyre-oligomerer omfattende universalbaser, fremstillingsfremgangsmåder deraf, og kits, indretninger og fremgangsmåder til analysen, detektering eller modulering af nukleinsyrer der anvender disse |
| JP2008283977A (ja) * | 2008-06-09 | 2008-11-27 | Toshiba Corp | 標的核酸の遺伝子型、および変異の判定方法、不溶性支持体に核酸断片を固定化する方法、所望の核酸を精製し、かつ増幅するための方法、並びに遺伝子型アッセイキット |
| CN101812537B (zh) * | 2009-10-27 | 2012-08-08 | 重庆医科大学 | 同时检测乙型肝炎病毒三种核苷酸类似物耐药位点的方法及其试剂盒 |
| US9045803B2 (en) | 2012-02-29 | 2015-06-02 | Abbott Molecular Inc. | Hepatitis B virus typing and resistance assay |
| KR20190076050A (ko) * | 2016-11-11 | 2019-07-01 | 얀센 바이오파마, 인크. | Hbv cccdna용 올리고뉴클레오티드 표적화 방법 |
| CN109609694B (zh) * | 2018-12-29 | 2022-03-01 | 上海昂朴生物科技有限公司 | 基于Illumina测序技术检测乙型肝炎分型及多耐药位点的试剂盒及方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2167056A1 (en) * | 1993-07-13 | 1995-01-26 | Uwe Spies | Nucleotide sequences and process for amplifying and detection of hepatitis b virus |
| US5667974A (en) * | 1995-06-07 | 1997-09-16 | Abbott Laboratories | Method for detecting nucleic acid sequences using competitive amplification |
| ZA973367B (en) * | 1996-04-19 | 1997-11-18 | Innogenetics Nv | Method for typing and detecting HBV. |
| AUPO351996A0 (en) * | 1996-11-08 | 1996-12-05 | Western Health Care Network | Viral variants and methods for detecting same |
-
2000
- 2000-07-03 AR ARP000103391A patent/AR028149A1/es unknown
- 2000-07-05 JP JP2001509556A patent/JP2003505021A/ja active Pending
- 2000-07-05 AU AU64317/00A patent/AU6431700A/en not_active Abandoned
- 2000-07-05 EP EP00951337A patent/EP1144693A3/en not_active Withdrawn
- 2000-07-05 CN CN00801329A patent/CN1384888A/zh active Pending
- 2000-07-05 TR TR2002/01797T patent/TR200201797T1/tr unknown
- 2000-07-05 BR BR0006899-3A patent/BR0006899A/pt not_active IP Right Cessation
- 2000-07-05 WO PCT/EP2000/006306 patent/WO2001004358A2/en not_active Ceased
- 2000-07-05 TR TR2001/00689T patent/TR200100689T1/tr unknown
- 2000-07-05 CA CA002339422A patent/CA2339422A1/en not_active Abandoned
-
2001
- 2001-02-28 ZA ZA200101680A patent/ZA200101680B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2003505021A (ja) | 2003-02-12 |
| CN1384888A (zh) | 2002-12-11 |
| TR200100689T1 (tr) | 2002-04-22 |
| AU6431700A (en) | 2001-01-30 |
| WO2001004358A3 (en) | 2001-08-30 |
| EP1144693A2 (en) | 2001-10-17 |
| AR028149A1 (es) | 2003-04-30 |
| WO2001004358A2 (en) | 2001-01-18 |
| ZA200101680B (en) | 2003-05-28 |
| EP1144693A3 (en) | 2001-11-28 |
| BR0006899A (pt) | 2001-06-12 |
| CA2339422A1 (en) | 2001-01-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Racanelli et al. | Molecular characterization of B cell clonal expansions in the liver of chronically hepatitis C virus-infected patients | |
| TR200201797T1 (tr) | Anti-hepaptit B ilacının direncinin saptanması | |
| DK1026262T3 (da) | Oligonukleotidprimere til effektiv detektering af hepatitis C-virus (HCV) og fremgangsmåder til anvendelse deraf | |
| EP4574992A3 (en) | Combinatorial dna screening | |
| DE69432225D1 (de) | Molekulare diagnose von familiärer adenomatöser polyposis | |
| DE69503129D1 (de) | Pteridin-nukleotidderivate als fluoreszierende sonden | |
| WO2000043791A3 (en) | Rapid and sensitive detection of aberrant protein aggregation in neurodegenerative diseases | |
| ATE432470T1 (de) | Verfahren zur unterscheidung des reizkolons von der entzündlichen darmerkrankung (inflammatory bowel disease, ibd) und zur überwachung von patienten mit ibd unter verwendung von endogenem gesamt-lactoferrin als marker | |
| DE60027045D1 (de) | Oligonukleotide und diese enthaltende komplexe zur detektion der anwesenheit oder abwesenheit einer zielnukleinsäure in einer probe | |
| TR200402517T1 (tr) | HBV ilaç direnci tespit metotları | |
| DE60125537D1 (de) | Zusammensetzung zur diagnose und behandlung von herpes simplex virusinfektionen | |
| DE69717840D1 (de) | Nachweis und identifizierung von nicht-polio enteroviren | |
| Tepper et al. | A biotinylated cpFIT-PNA platform for the facile detection of drug resistance to artemisinin in plasmodium falciparum | |
| FR2680520B1 (fr) | Procede de detection de nouvelles regions hypervariables dans une sequence d'adn, sequences de nucleotides constituant des sondes d'hybridation et leur application biologique. | |
| DE60136746D1 (de) | Oligonucleotide zur markierung von oligonukleotidsonden und proteine | |
| Skogerboe | Molecular biology techniques | |
| ATE187204T1 (de) | Direkter nachweis der rns des hepatitis-c-virus | |
| MXPA02000293A (es) | Isoformas de la amp ciclico fosfodiesterasa y metodos de uso. | |
| DE60025336D1 (de) | Verfahren und kit zur früherkennung von krebs | |
| Bowden et al. | New developments in HBV molecular diagnostics and quantitative serology | |
| FR2791357B1 (fr) | Diagnostic de la maladie de whipple | |
| Tsao et al. | Detection of low copies of drug-resistant influenza viral gene by a single-tube reaction using peptide nucleic acid as both PCR clamp and sensor probe | |
| FI990380A7 (fi) | Diagnostinen ja seulontamenetelmä | |
| ATE381713T1 (de) | Verfahren und zusammensetzungen zum nachweis von taenia solium larven mittels eines klonierten antigens | |
| Müller et al. | Hepatitis C virus genotypes in Hungarian and Austrian patients with chronic hepatitis C |