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TR200001858T2 - Ampisilin Ön-ilaç ester solüsyonunun saflaştırılması için usul - Google Patents

Ampisilin Ön-ilaç ester solüsyonunun saflaştırılması için usul

Info

Publication number
TR200001858T2
TR200001858T2 TR2000/01858T TR200001858T TR200001858T2 TR 200001858 T2 TR200001858 T2 TR 200001858T2 TR 2000/01858 T TR2000/01858 T TR 2000/01858T TR 200001858 T TR200001858 T TR 200001858T TR 200001858 T2 TR200001858 T2 TR 200001858T2
Authority
TR
Turkey
Prior art keywords
purification
prodrug ester
ester solution
ampicillin
phase extraction
Prior art date
Application number
TR2000/01858T
Other languages
English (en)
Inventor
Federsel Hans-J�rgen
K�Nberg Er�K
Original Assignee
Asrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9704868A external-priority patent/SE9704868D0/xx
Priority claimed from SE9800255A external-priority patent/SE9800255D0/xx
Application filed by Asrazeneca Ab filed Critical Asrazeneca Ab
Publication of TR200001858T2 publication Critical patent/TR200001858T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/04—Preparation
    • C07D499/18—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Bir ampisilin ön-ilacin solüsyonunun örnegin basampisilinin, veya bunun bir asit et tuzunun solüsyonunun saflastirilmasi için usul ki bu usulde ham solüsyon, istenen saflastirilmis ön-ilaç esterinin veya bunun bir tuzunun kristalize olmasi için yapilan sürekli bir operasyonu içeren organik çözücünün buharlasma orani ile kontrol edilen bir buharlasmaya tabidir. Söz konusu kristallesme tercihen sulu bir faz özütlemesi ve/veya organik faz özütlemesi, sürekli olmak üzere her ikisi de yapilarak gerçeklestirillen bir islemdir.
TR2000/01858T 1997-12-22 1998-12-16 Ampisilin Ön-ilaç ester solüsyonunun saflaştırılması için usul TR200001858T2 (tr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9704868A SE9704868D0 (sv) 1997-12-22 1997-12-22 New process
SE9800255A SE9800255D0 (sv) 1998-01-29 1998-01-29 New process

Publications (1)

Publication Number Publication Date
TR200001858T2 true TR200001858T2 (tr) 2000-10-23

Family

ID=26663170

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/01858T TR200001858T2 (tr) 1997-12-22 1998-12-16 Ampisilin Ön-ilaç ester solüsyonunun saflaştırılması için usul

Country Status (21)

Country Link
US (1) US6414141B1 (tr)
EP (1) EP1049702B1 (tr)
JP (1) JP2001526291A (tr)
KR (1) KR20010024788A (tr)
CN (1) CN1284959A (tr)
AR (1) AR014939A1 (tr)
AU (1) AU741292B2 (tr)
BR (1) BR9814388A (tr)
CA (1) CA2315082A1 (tr)
DZ (1) DZ2687A1 (tr)
EE (1) EE200000389A (tr)
EG (1) EG21726A (tr)
HU (1) HUP0100403A3 (tr)
IL (1) IL136879A0 (tr)
IS (1) IS5530A (tr)
MA (1) MA26578A1 (tr)
NO (1) NO20002988L (tr)
NZ (1) NZ505166A (tr)
TN (1) TNSN98228A1 (tr)
TR (1) TR200001858T2 (tr)
WO (1) WO1999032493A1 (tr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7463626B2 (en) * 2000-11-21 2008-12-09 Roy Subhash C Phase and frequency drift and jitter compensation in a distributed telecommunications switch
US20040215003A1 (en) * 2002-11-12 2004-10-28 Dobbins Thomas A. Method for purifying and separating soy isoflavones
CN102284192B (zh) * 2011-06-16 2013-06-12 北京科技大学 并、逆流耦合式连续反萃青霉素设备及工艺
CN111039984B (zh) 2018-10-15 2022-06-07 上海盟科药业股份有限公司 康泰唑胺酯的药物晶体及其制备方法和应用
KR20230056433A (ko) 2021-10-20 2023-04-27 현대자동차주식회사 전자기판용 보호코팅 조성물 및 이의 제조방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3905959A (en) * 1973-05-07 1975-09-16 Pfizer Process for the manufacture of crystalline anhydrous ampicillin
NZ189945A (en) 1978-04-01 1981-04-24 Beecham Group Ltd Ampicillin phthalidyl ester naphthalene 2-sulphonate also pharmaceutical compositions
IL67637A0 (en) * 1983-01-07 1983-05-15 Orvet Bv Preparation of 1'-ethoxycarbonyl-oxyethyl esters of penicillins and novel intermediates
IT1214587B (it) * 1986-12-23 1990-01-18 Giovanni Bonfanti Metodo per la produzione diprodotti cristallini puri.

Also Published As

Publication number Publication date
NO20002988D0 (no) 2000-06-09
AU741292B2 (en) 2001-11-29
AR014939A1 (es) 2001-04-11
IL136879A0 (en) 2001-06-14
US6414141B1 (en) 2002-07-02
TNSN98228A1 (fr) 2005-03-15
KR20010024788A (ko) 2001-03-26
EG21726A (en) 2002-02-27
HUP0100403A2 (hu) 2001-08-28
JP2001526291A (ja) 2001-12-18
EE200000389A (et) 2001-12-17
NO20002988L (no) 2000-06-09
HUP0100403A3 (en) 2001-12-28
CA2315082A1 (en) 1999-07-01
MA26578A1 (fr) 2004-12-20
CN1284959A (zh) 2001-02-21
NZ505166A (en) 2002-02-01
AU1990399A (en) 1999-07-12
BR9814388A (pt) 2000-10-10
DZ2687A1 (fr) 2003-03-29
IS5530A (is) 2000-06-13
EP1049702B1 (en) 2003-03-19
WO1999032493A1 (en) 1999-07-01
EP1049702A1 (en) 2000-11-08

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