TNSN86004A1 - Compose pharmaceutiquement actif et procede pour sa preparation - Google Patents
Compose pharmaceutiquement actif et procede pour sa preparationInfo
- Publication number
- TNSN86004A1 TNSN86004A1 TNTNSN86004A TNSN86004A TNSN86004A1 TN SN86004 A1 TNSN86004 A1 TN SN86004A1 TN TNSN86004 A TNTNSN86004 A TN TNSN86004A TN SN86004 A TNSN86004 A TN SN86004A TN SN86004 A1 TNSN86004 A1 TN SN86004A1
- Authority
- TN
- Tunisia
- Prior art keywords
- preparation
- active compound
- pharmaceutically active
- treatment
- compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 230000001575 pathological effect Effects 0.000 abstract 2
- YJGVMLPVUAXIQN-UHFFFAOYSA-N epipodophyllotoxin Natural products COC1=C(OC)C(OC)=CC(C2C3=CC=4OCOC=4C=C3C(O)C3C2C(OC3)=O)=C1 YJGVMLPVUAXIQN-UHFFFAOYSA-N 0.000 abstract 1
- 239000008196 pharmacological composition Substances 0.000 abstract 1
- YJGVMLPVUAXIQN-XVVDYKMHSA-N podophyllotoxin Chemical compound COC1=C(OC)C(OC)=CC([C@@H]2C3=CC=4OCOC=4C=C3[C@H](O)[C@@H]3[C@@H]2C(OC3)=O)=C1 YJGVMLPVUAXIQN-XVVDYKMHSA-N 0.000 abstract 1
- 229960001237 podophyllotoxin Drugs 0.000 abstract 1
- YVCVYCSAAZQOJI-UHFFFAOYSA-N podophyllotoxin Natural products COC1=C(O)C(OC)=CC(C2C3=CC=4OCOC=4C=C3C(O)C3C2C(OC3)=O)=C1 YVCVYCSAAZQOJI-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Virology (AREA)
- Pain & Pain Management (AREA)
- Tropical Medicine & Parasitology (AREA)
- Dermatology (AREA)
- Transplantation (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
L'INVENTION CONCERNE DES COMPOSES CONSISTANT EN PODOPHYLLOTOXINE ET EN SES DERIVES DE FORMULE (I). DANS LAQUELLE R1 REPRESENTE H OU OH ET R2 REPRESENTE H OU CH3, POUR LE TRAITEMENT DE CERTAINS ETATS PATHOLOGIQUES, ET UN PROCEDE PERMETTANT DE LES OBTENIR. L'INVENTION CONCERNE EN OUTRE L'UTILISATION DES COMPOSES POUR LE TRAITEMENT DES DITS ETATS PATHOLOGIQUES AINSI QUE L'UTILISATION DES DITS COMPOSES POUR LA PREPARATION DES COMPOSITIONS PHARMACOLOGIQUES DESTINEES AU TRAITEMENT DES DITS ETATS PATHOLOGIQUES
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8406660 | 1984-12-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TNSN86004A1 true TNSN86004A1 (fr) | 1990-01-01 |
Family
ID=20358339
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TNTNSN86004A TNSN86004A1 (fr) | 1984-12-28 | 1986-01-09 | Compose pharmaceutiquement actif et procede pour sa preparation |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US4788216A (fr) |
| EP (1) | EP0207124B1 (fr) |
| JP (2) | JPH0720966B2 (fr) |
| CN (1) | CN1006795B (fr) |
| AP (1) | AP32A (fr) |
| AT (1) | ATE68186T1 (fr) |
| AU (1) | AU585936B2 (fr) |
| CA (1) | CA1255230A (fr) |
| DE (1) | DE3584370D1 (fr) |
| DK (1) | DK169506B1 (fr) |
| DZ (1) | DZ876A1 (fr) |
| EG (1) | EG17788A (fr) |
| ES (1) | ES8701761A1 (fr) |
| FI (1) | FI89330C (fr) |
| GR (1) | GR853145B (fr) |
| HU (1) | HU201672B (fr) |
| IL (1) | IL77456A (fr) |
| MA (1) | MA20602A1 (fr) |
| NO (1) | NO863329L (fr) |
| PT (1) | PT81760B (fr) |
| TN (1) | TNSN86004A1 (fr) |
| WO (1) | WO1986004062A1 (fr) |
| ZA (1) | ZA859881B (fr) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4644072A (en) * | 1985-04-12 | 1987-02-17 | Bristol-Myers Company | Intermediates for the production of epipodophyllotoxin and related compounds and processes for the preparation and use thereof |
| EP0461141B1 (fr) * | 1989-02-23 | 1999-11-03 | University Of North Carolina At Chapel Hill | Analogues d'etoposide |
| SE464167B (sv) | 1989-07-31 | 1991-03-18 | Analytecon Sa | Topisk farmaceutisk beredning av podophyllotoxin |
| US5332811A (en) * | 1989-09-12 | 1994-07-26 | The University Of North Carolina At Chapel Hill | Etopside analogs |
| US5338867A (en) * | 1992-04-24 | 1994-08-16 | Genelabs Technologies, Inc. | Preparation of 4β- amino podophyllotoxin compounds |
| SE9301831D0 (sv) * | 1993-05-28 | 1993-05-28 | Analytecon S A | Pharmaceutical compositions |
| GB9422947D0 (en) * | 1994-11-14 | 1995-01-04 | Univ Salamanca | Immunosuppressive cyclolignan derivatives |
| US6051721A (en) * | 1997-10-02 | 2000-04-18 | The Board Of Regents Of The University Of Nebraska | Ring E-modified analogues of(-)-podophyllotoxin and etoposide and a method for their synthesis |
| FI105152B (fi) * | 1998-07-17 | 2000-06-30 | Eero Saarela | Paikallinen kivunlievitysmenetelmä |
| US6143304A (en) * | 1999-08-17 | 2000-11-07 | The University Of Mississippi | Enhanced yield of podophyllotoxin from natural products through in situ conversion methods |
| SE0102168D0 (sv) | 2001-06-19 | 2001-06-19 | Karolinska Innovations Ab | New use and new compounds |
| KR20040030686A (ko) * | 2001-06-19 | 2004-04-09 | 악셀라르 아베 | 시클로리그난의 신규의 용도 및 신규의 시클로리그난 |
| SE0203746D0 (sv) * | 2002-12-18 | 2002-12-18 | Karolinska Innovations Ab | New compounds |
| JP2011525486A (ja) * | 2008-06-23 | 2011-09-22 | アクセラー エービー | 活動亢進性免疫系を治療するためのシクロリグナンの使用 |
| EP2817007A1 (fr) * | 2012-02-24 | 2014-12-31 | Nestec S.A. | Peltatine destinée à être utilisée pour traiter des troubles inflammatoires chroniques |
| WO2015028456A1 (fr) * | 2013-08-28 | 2015-03-05 | Nestec S.A. | Modulateurs des rapp |
| JOP20190254A1 (ar) | 2017-04-27 | 2019-10-27 | Pharma Mar Sa | مركبات مضادة للأورام |
| AU2020245715B2 (en) * | 2019-03-22 | 2025-12-18 | Integrated Nanotherapeutics Inc. | Lipid conjugate prepared from scaffold moiety |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA635769A (en) * | 1962-01-30 | Rutschmann Jurg | Amides of podophyllic acid and picropodophyllic acid | |
| SE335139B (fr) * | 1964-08-12 | 1971-05-17 | Sandoz Ag | |
| US4122092A (en) * | 1977-08-25 | 1978-10-24 | University Of Rochester | Total synthesis of (±)-picropodophyllone and (±)-4'-demethylpicropodophyllone |
| US4567253A (en) * | 1984-02-03 | 1986-01-28 | Tony Durst | 2-Substituted derivatives of podophyllotoxin and etoposide |
| GB8424269D0 (en) * | 1984-09-26 | 1984-10-31 | Pharma Medica As | Isolation and purification of podophyllotoxin |
-
1985
- 1985-12-20 JP JP61500490A patent/JPH0720966B2/ja not_active Expired - Lifetime
- 1985-12-20 DE DE8686900345T patent/DE3584370D1/de not_active Expired - Fee Related
- 1985-12-20 AT AT86900345T patent/ATE68186T1/de not_active IP Right Cessation
- 1985-12-20 AU AU53003/86A patent/AU585936B2/en not_active Ceased
- 1985-12-20 WO PCT/SE1985/000541 patent/WO1986004062A1/fr not_active Ceased
- 1985-12-20 HU HU86777D patent/HU201672B/hu not_active IP Right Cessation
- 1985-12-20 US US06/908,801 patent/US4788216A/en not_active Expired - Lifetime
- 1985-12-20 EP EP86900345A patent/EP0207124B1/fr not_active Expired - Lifetime
- 1985-12-23 AP APAP/P/1985/000017A patent/AP32A/en active
- 1985-12-24 CA CA000498645A patent/CA1255230A/fr not_active Expired
- 1985-12-25 EG EG828/85A patent/EG17788A/xx active
- 1985-12-26 MA MA20828A patent/MA20602A1/fr unknown
- 1985-12-26 PT PT81760A patent/PT81760B/pt not_active IP Right Cessation
- 1985-12-26 IL IL77456A patent/IL77456A/xx unknown
- 1985-12-27 ES ES550504A patent/ES8701761A1/es not_active Expired
- 1985-12-27 CN CN85109666A patent/CN1006795B/zh not_active Expired
- 1985-12-27 GR GR853145A patent/GR853145B/el not_active IP Right Cessation
- 1985-12-28 DZ DZ850275A patent/DZ876A1/fr active
- 1985-12-30 ZA ZA859881A patent/ZA859881B/xx unknown
-
1986
- 1986-01-09 TN TNTNSN86004A patent/TNSN86004A1/fr unknown
- 1986-08-19 NO NO863329A patent/NO863329L/no unknown
- 1986-08-27 FI FI863482A patent/FI89330C/fi not_active IP Right Cessation
- 1986-08-27 DK DK408186A patent/DK169506B1/da not_active IP Right Cessation
-
1994
- 1994-10-14 JP JP6274258A patent/JP2572558B2/ja not_active Expired - Fee Related
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TNSN86004A1 (fr) | Compose pharmaceutiquement actif et procede pour sa preparation | |
| TNSN97070A1 (fr) | Derives d'imidazole substitues, procede pour leur preparation, et compositions les contenant | |
| YU48323B (sh) | Postupak za dobijanje askorbinske kiseline | |
| FR2446289A1 (fr) | Compose de 2-penem, procede de preparation et composition pharmaceutique obtenue | |
| EP1251125A3 (fr) | Nouveaux analogues de la camptoth-cine, des proc-d-s de pr-paration, leur application comme m-dicaments et les compositions pharmaceutiques les contenant | |
| TNSN87033A1 (fr) | TOLUNITRILES SUBSTITUES PAR DESα - HETEROCYCLES | |
| PT78179A (fr) | Procede de preparation de nouveaux sulfates avec activite anti--thrombotique et hypolipemiante et de compositions pharmaceuti-ques les contenant | |
| FR2407926A1 (fr) | Derives de quinazoline, leur procede de production et composition pharmaceutique les contenant | |
| FR2397403A1 (fr) | Nouveaux derives de 1-acyl 2-cyano-aziridine, procede pour leur preparation et compositions pharmaceutiques contenant ces composes | |
| EP0244803A3 (fr) | Inhibiteurs de dopamine-bêta-hydroxylase | |
| TNSN99013A1 (fr) | Derives d'acide dihydroxyhexanoique nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant | |
| BE901301A (fr) | 5-pyrimidine-carboxamides et thiocarboamides, ainsi que le traitement de la leucemie et des tumeurs avec ces substances. | |
| FR2418789A1 (fr) | Nouveaux sels de guanidine, procede permettant leur production et preparations microbicides les contenant | |
| FR2446829A1 (fr) | Derives de polymethylene disubstitues en alpha, omega, procede pour leur preparation et compositions pharmaceutiques les contenant | |
| FR2395272A1 (fr) | Nouveaux medicaments derives de l'acide amidinopenicillanique | |
| IT8420358A0 (it) | Procedimento di preparazione di derivati 1-carbamoilmetilici di 4-idrossi-2-osso-pirrolidina nonche' di intermedi per ottenere tali composti. | |
| BE893492A (fr) | Procede de preparation d'esters d'acides apovincaminiques, esters ainsi obtenus et compositions pharmaceutiques prepares avec ces esters | |
| FR2601680B1 (fr) | Inhibiteur de la synthese proteique, procede d'isolement, utilisation et compositions pharmaceutiques en contenant | |
| FR2416013A1 (fr) | Derives d'acide (-)-(cis)-1,2-epoxypropylphosphonique, leur preparation et compositions pharmaceutiques les contenant | |
| FR2653771B1 (fr) | Procede de preparation de l'azt (azido-3'-desoxy-3'-thymidine) et de composes apparentes. | |
| FR2506766A1 (fr) | Sel de l-lysine ou de dl-lysine de l'acide 5-(p-chlorobenzoyl)-1,4-dimethylpyrrole-2-acetique, son procede de preparation et composition analgesique le contenant | |
| TNSN86056A1 (fr) | Procede de preparation de derives d'azetidine | |
| FR2376863A1 (fr) | Determination du 1a,25-dihydroxycholecalciferol | |
| BE1000719A4 (fr) | Derives de 3-(hydroxymethyl)-isoquinoleine, procede pour les preparer et compositions pharmaceutiques les contenant. | |
| TNSN86165A1 (fr) | Nouveaux ortho-anisamides, leur procede d'obtention et leurs applications therapeutiques |