SV2008002952A - Uso de derivados de sulfamida heterociclica benzo-fusionada para el tratamiento de obesidad referencia cruzada a solicitudes relacionadas ref. prd2586sv - Google Patents
Uso de derivados de sulfamida heterociclica benzo-fusionada para el tratamiento de obesidad referencia cruzada a solicitudes relacionadas ref. prd2586svInfo
- Publication number
- SV2008002952A SV2008002952A SV2008002952A SV2008002952A SV2008002952A SV 2008002952 A SV2008002952 A SV 2008002952A SV 2008002952 A SV2008002952 A SV 2008002952A SV 2008002952 A SV2008002952 A SV 2008002952A SV 2008002952 A SV2008002952 A SV 2008002952A
- Authority
- SV
- El Salvador
- Prior art keywords
- obesity
- benzo
- processing
- prd2586sv
- heterociclic
- Prior art date
Links
- 208000008589 Obesity Diseases 0.000 title abstract 2
- 235000020824 obesity Nutrition 0.000 title abstract 2
- NVBFHJWHLNUMCV-UHFFFAOYSA-N sulfamide Chemical class NS(N)(=O)=O NVBFHJWHLNUMCV-UHFFFAOYSA-N 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 abstract 1
- 230000004580 weight loss Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Obesity (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pyrane Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
USO DE UNO O MAS DERIVADOS DE SULFAMIDA HETEROCICLICA BENZO-FUSIONADA NOVEDOSA DE FORMULA (I) COMO SE DEFINEN AQUI, EN LA ELABORACION DE UN MEDICAMENTO EFICAZ PARA EL TRATAMIENTO DE OBESIDAD, PARA PROMOVER LA PÉRDIDA DE PESO Y/O SUPRIMIR EL APETITO
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75149905P | 2005-12-19 | 2005-12-19 | |
| US11/611,938 US8492431B2 (en) | 2005-12-19 | 2006-12-18 | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of obesity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SV2008002952A true SV2008002952A (es) | 2010-01-18 |
Family
ID=37992995
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SV2008002952A SV2008002952A (es) | 2005-12-19 | 2008-06-19 | Uso de derivados de sulfamida heterociclica benzo-fusionada para el tratamiento de obesidad referencia cruzada a solicitudes relacionadas ref. prd2586sv |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US8492431B2 (es) |
| EP (1) | EP1968574B9 (es) |
| JP (1) | JP5190378B2 (es) |
| KR (1) | KR101363308B1 (es) |
| CN (1) | CN101365442B (es) |
| AR (1) | AR058389A1 (es) |
| AT (1) | ATE519484T1 (es) |
| AU (1) | AU2006331637B2 (es) |
| BR (1) | BRPI0620019A2 (es) |
| CA (1) | CA2634093C (es) |
| CR (1) | CR10164A (es) |
| CY (1) | CY1112357T1 (es) |
| DK (1) | DK1968574T3 (es) |
| EA (1) | EA016560B1 (es) |
| ES (1) | ES2369761T3 (es) |
| HR (1) | HRP20110726T2 (es) |
| IL (1) | IL192107A (es) |
| ME (1) | ME01344B (es) |
| MY (1) | MY145823A (es) |
| NO (1) | NO20083006L (es) |
| NZ (1) | NZ568960A (es) |
| PE (1) | PE20070813A1 (es) |
| PL (1) | PL1968574T3 (es) |
| PT (1) | PT1968574E (es) |
| RS (1) | RS52044B (es) |
| SI (1) | SI1968574T1 (es) |
| SV (1) | SV2008002952A (es) |
| UY (1) | UY30033A1 (es) |
| WO (1) | WO2007075833A2 (es) |
| ZA (1) | ZA200806279B (es) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY147767A (en) | 2004-06-16 | 2013-01-31 | Janssen Pharmaceutica Nv | Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders |
| JP2008545650A (ja) * | 2005-05-20 | 2008-12-18 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | スルファミド誘導体の製造方法 |
| US8937096B2 (en) | 2005-12-19 | 2015-01-20 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of mania and bipolar disorder |
| US20070155827A1 (en) * | 2005-12-19 | 2007-07-05 | Smith-Swintosky Virginia L | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of depression |
| US8492431B2 (en) | 2005-12-19 | 2013-07-23 | Janssen Pharmaceutica, N.V. | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of obesity |
| US8497298B2 (en) | 2005-12-19 | 2013-07-30 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels |
| US8691867B2 (en) | 2005-12-19 | 2014-04-08 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of substance abuse and addiction |
| WO2007137167A2 (en) | 2006-05-19 | 2007-11-29 | Janssen Pharmaceutica N.V. | Co-therapy for the treatment of epilepsy |
| US20090247616A1 (en) * | 2008-03-26 | 2009-10-01 | Smith-Swintosky Virginia L | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of anxiety |
| CA2722986A1 (en) * | 2008-04-29 | 2009-11-05 | Nsab, Filial Af Neurosearch Sweden Ab, Sverige | Modulators of dopamine neurotransmission |
| DK2271634T3 (da) | 2008-04-29 | 2014-05-05 | Integrative Res Lab Sweden Ab | Modulatorer af dopamin-neurotransmission |
| JP2011519839A (ja) * | 2008-04-29 | 2011-07-14 | エヌエスエイビー、フィリアル アヴ ノイロサーチ スウェーデン エービー、スヴェーリエ | ドーパミン神経伝達のモジュレーター |
| PE20110060A1 (es) | 2008-06-23 | 2011-01-31 | Janssen Pharmaceutica Nv | Forma cristalina de (2s)-(-)-n-(6-cloro-2,3-dihidro-benzo[1,4]dioxin-2-ilmetil)-sulfamida |
| US8815939B2 (en) * | 2008-07-22 | 2014-08-26 | Janssen Pharmaceutica Nv | Substituted sulfamide derivatives |
| CA2850513A1 (en) | 2011-09-29 | 2013-04-04 | Janssen Pharmaceutica Nv | Process for the preparation of sulfamide derivatives |
| CA2850015A1 (en) | 2011-09-29 | 2013-04-04 | Janssen Pharmaceutica Nv | Improved process for the preparation of sulfamide derivatives |
Family Cites Families (106)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2527861A (en) * | 1948-05-07 | 1950-10-31 | Monsanto Chemicals | Mono alkyl sulfamides |
| BE636655A (es) * | 1962-09-14 | |||
| DE1211166B (de) | 1962-11-20 | 1966-02-24 | Ciba Geigy | Verfahren zur Herstellung neuer Sulfamide |
| US3318952A (en) * | 1964-01-22 | 1967-05-09 | Sandoz Ag | Dibenzylsulfamides |
| US3320314A (en) | 1964-01-22 | 1967-05-16 | Sandoz Ag | Chlorobenzyl sulfamides |
| US3383414A (en) * | 1964-08-26 | 1968-05-14 | Sandoz Ag | Benzocycloalkyl sulfamides |
| DE1542785A1 (de) | 1965-07-24 | 1970-05-06 | Bayer Ag | Insekten- und milbenabweisende Mittel |
| US3539573A (en) * | 1967-03-22 | 1970-11-10 | Jean Schmutz | 11-basic substituted dibenzodiazepines and dibenzothiazepines |
| US3621096A (en) * | 1969-04-03 | 1971-11-16 | Univ North Carolina | Antidepressant method and composition for same comprising a tricyclic antidepressant and a thyroid hormone |
| DE2022370A1 (de) | 1970-05-08 | 1971-12-02 | Bayer Ag | N-Fluordichlormethylthio-sulfamidsaeure-Derivate,Verfahren zu ihrer Herstellung und ihre mikrobizide und fungizide Verwendung |
| US5212326A (en) * | 1979-08-20 | 1993-05-18 | Abbott Laboratories | Sodium hydrogen divalproate oligomer |
| FR2479825A1 (fr) * | 1980-04-04 | 1981-10-09 | Fabre Sa Pierre | Benzodioxanne 1,4 methoxy-2 propanolamines, leur preparation et leur application en tant que medicaments |
| US4513006A (en) * | 1983-09-26 | 1985-04-23 | Mcneil Lab., Inc. | Anticonvulsant sulfamate derivatives |
| US4804663A (en) * | 1985-03-27 | 1989-02-14 | Janssen Pharmaceutica N.V. | 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles |
| IE58370B1 (en) * | 1985-04-10 | 1993-09-08 | Lundbeck & Co As H | Indole derivatives |
| GB8607684D0 (en) * | 1986-03-27 | 1986-04-30 | Ici America Inc | Thiazepine compounds |
| US4831031A (en) * | 1988-01-22 | 1989-05-16 | Pfizer Inc. | Aryl piperazinyl-(C2 or C4) alkylene heterocyclic compounds having neuroleptic activity |
| US5158952A (en) * | 1988-11-07 | 1992-10-27 | Janssen Pharmaceutica N.V. | 3-[2-[4-(6-fluoro-1,2-benzisoxozol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9 tetrahydro-9-hydroxy-2-methyl-4H-pyrido [1,2-a]pyrimidin-4-one, compositions and method of use |
| US5238945A (en) * | 1989-04-11 | 1993-08-24 | H. Lundbeck A/S | Method of treating psychoses |
| GB8908085D0 (en) * | 1989-04-11 | 1989-05-24 | Lundbeck & Co As H | New therapeutic use |
| US5273993A (en) * | 1989-06-12 | 1993-12-28 | A. H. Robins Company, Incorporated | Compounds having one or more aminosulfonyloxy radicals useful as pharmaceuticals |
| US5194446A (en) * | 1989-06-12 | 1993-03-16 | A. H. Robins Company, Incorporated | Compounds having one or more aminosulfaonyloxy radicals useful as pharmaceuticals |
| US5192785A (en) * | 1989-09-03 | 1993-03-09 | A. H. Robins Company, Incorporated | Sulfamates as antiglaucoma agents |
| US5229382A (en) * | 1990-04-25 | 1993-07-20 | Lilly Industries Limited | 2-methyl-thieno-benzodiazepine |
| US5189179A (en) | 1990-08-29 | 1993-02-23 | Merrell Dow Pharmaceuticals Inc. | Serotonin 5ht1a agonists |
| CA2054339C (en) | 1990-11-02 | 2002-12-24 | Francesco G. Salituro | 3-amidoindolyl derivatives |
| GB9026998D0 (en) | 1990-12-12 | 1991-01-30 | Glaxo Group Ltd | Medicaments |
| US5120758A (en) | 1991-02-08 | 1992-06-09 | Ciba-Geigy Corporation | Certain benzodioxole, benzodioxane and benzodioxepin derivatives useful as 5-lipoxygenase inhibitors |
| GB9104890D0 (en) | 1991-03-08 | 1991-04-24 | Glaxo Group Ltd | Compositions |
| IL103172A (en) * | 1991-09-19 | 1997-01-10 | Mcneilab Inc | Preparation of chlorosulfate and sulfamate derivatives of 2, 3:4, 5-bis-o-(1-methylethylidene)-beta-d-fructopyranose and (1-methylcyclohexyl) methanol |
| US5242942A (en) * | 1992-04-28 | 1993-09-07 | Mcneilab, Inc. | Anticonvulsant fructopyranose cyclic sulfites and sulfates |
| US5258402A (en) * | 1992-06-11 | 1993-11-02 | Mcneil-Ppc, Inc. | Imidate derivatives of pharmaceutically useful anticonvulsant sulfamates |
| US5312925A (en) * | 1992-09-01 | 1994-05-17 | Pfizer Inc. | Monohydrate of 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)-ethyl)-6-chloro-1,3-dihydro-2H-indol-2-one-hydrochloride |
| US5384327A (en) * | 1992-12-22 | 1995-01-24 | Mcneilab, Inc. | Anticonvulsant sorbopyranose sulfamates |
| DE69434652T2 (de) | 1993-12-23 | 2007-03-01 | Ortho-Mcneil Pharmaceutical, Inc. | Antikonvulsive pseudofructopyranose sulfamate |
| GB9417532D0 (en) | 1994-08-31 | 1994-10-19 | Zeneca Ltd | Aromatic compounds |
| ATE204852T1 (de) * | 1995-02-15 | 2001-09-15 | Bearsden Bio Inc | Alkylcarboxy-aminosäure modulatoren für den kainat-rezeptor |
| JP3235448B2 (ja) * | 1995-03-24 | 2001-12-04 | ダイソー株式会社 | 1,4−ベンゾジオキサン誘導体の製法 |
| US5998380A (en) * | 1995-10-13 | 1999-12-07 | New England Medical Center Hospitals, Inc. | Treatment of migraine |
| KR19990071666A (ko) | 1995-11-30 | 1999-09-27 | 이경하 | 술파미드 유도체 |
| WO1997019682A1 (en) | 1995-12-01 | 1997-06-05 | Synaptic Pharmaceutical Corporation | Aryl sulfonamide and sulfamide derivatives and uses thereof |
| AU2587297A (en) | 1996-03-25 | 1997-10-17 | Eli Lilly And Company | Method for treating pain |
| AU3501697A (en) | 1996-06-28 | 1998-01-21 | Ortho Pharmaceutical Corporation | Use of topiramate or derivatives thereof for the manufacture of a medicament for the treatment of postischemic neurodegeneration |
| PT915697E (pt) | 1996-06-28 | 2003-02-28 | Ortho Mcneil Pharm Inc | Anticonvulsionantes derivados do sulfamato uteis no tratamento da obesidade |
| US5753694A (en) * | 1996-06-28 | 1998-05-19 | Ortho Pharmaceutical Corporation | Anticonvulsant derivatives useful in treating amyotrophic lateral sclerosis (ALS) |
| US5753693A (en) | 1996-06-28 | 1998-05-19 | Ortho Pharmaceutical Corporation | Anticonvulsant derivatives useful in treating manic-depressive bipolar disorder |
| AU722072B2 (en) | 1996-08-14 | 2000-07-20 | G.D. Searle & Co. | Crytalline form of 4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide |
| AU4078897A (en) | 1996-08-23 | 1998-03-06 | Algos Pharmaceutical Corporation | Anticonvulsant containing composition for treating neuropathic pain |
| US20020015713A1 (en) * | 1996-10-24 | 2002-02-07 | Murdock Robert W. | Methods and transdermal compositions for pain relief |
| US5935933A (en) * | 1997-07-16 | 1999-08-10 | Ortho-Mcneil Pharmaceutical, Inc. | Anticonvulsant derivatives useful in treating neuropathic pain |
| US5760007A (en) * | 1997-07-16 | 1998-06-02 | Ortho Pharmaceutical Corporation | Anticonvulsant derivatives useful in treating neuropathic pain |
| DE69827149T2 (de) * | 1997-08-15 | 2006-03-09 | Fairbanks, Carolyn Ann, Rochester | Agmatin für die behandlung neuropathischer schmerzen |
| GB9803536D0 (en) | 1998-02-19 | 1998-04-15 | Black James Foundation | Histamine H,receptor ligands |
| UA65607C2 (uk) | 1998-03-04 | 2004-04-15 | Орто-Макнейл Фармацевтикал, Інк. | Фармацевтична композиція (варіанти) та спосіб її приготування |
| DK72798A (da) | 1998-05-28 | 1998-05-28 | Novo Nordisk As | Treatment of GABA-uptake related disorders |
| JP2002519373A (ja) | 1998-07-02 | 2002-07-02 | エーザイ株式会社 | 製薬組成物及びそれらの使用 |
| US6541520B1 (en) | 1998-08-05 | 2003-04-01 | Brookhaven Science Associates | Treatment of addiction and addiction-related behavior |
| DE60015070T2 (de) | 1999-01-19 | 2006-01-05 | Ortho-Mcneil Pharmaceutical, Inc. | Verwendung von antikonvulsiven derivaten zur behandlung der cluster headache |
| AR022321A1 (es) | 1999-01-21 | 2002-09-04 | Ortho Mcneil Pharm Inc | Derivados de anticonvulsivo utiles para el tratamiento de la migrana transformada |
| CZ20013061A3 (cs) | 1999-02-24 | 2002-06-12 | University Of Cincinnati | Pouľití sulfamátových derivátů pro léčbu poruch kontroly impulsů |
| WO2000054588A1 (en) | 1999-03-15 | 2000-09-21 | John Claude Krusz | Treatment of acute headaches and chronic pain using rapidly-cleared anesthetic drug at sub-anesthetic dosages |
| JP2002541199A (ja) * | 1999-04-08 | 2002-12-03 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | 脂質を下げることに有用な抗痙攣薬誘導体 |
| WO2000061140A1 (en) | 1999-04-08 | 2000-10-19 | Ortho-Mcneil Pharmaceutical, Inc. | Anticonvulsant derivatives useful in maintaining weight loss |
| AU782344C (en) * | 1999-04-08 | 2006-08-17 | Ortho-Mcneil Pharmaceutical, Inc. | Anticonvulsant derivatives useful in treating chronic neurodegenerative disorders |
| NZ514811A (en) | 1999-04-08 | 2005-01-28 | Ortho Mcneil Pharm Inc | Anticonvulsant derivatives useful in reducing blood glucose levels |
| WO2000066109A2 (en) | 1999-05-04 | 2000-11-09 | Edwards Keith R | Intravenous valproate for acute treatment of migraine headache |
| CA2377330C (en) | 1999-06-14 | 2009-11-24 | Thomas Najarian | Combination therapy for effecting weight loss and treating obesity |
| ATE284223T1 (de) | 1999-08-20 | 2004-12-15 | Ortho Mcneil Pharm Inc | Zusammensetzung enthaltend ein tramadol und ein antikonvulsives arzneimittel |
| FR2803848B1 (fr) | 2000-01-19 | 2002-02-15 | Adir | Nouveaux derives de benzenesulfonamide, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| US6322503B1 (en) * | 2000-02-17 | 2001-11-27 | G. Roger Sparhawk, Jr. | Method of diagnosing, tracking, and treating depression |
| US20010036943A1 (en) | 2000-04-07 | 2001-11-01 | Coe Jotham W. | Pharmaceutical composition for treatment of acute, chronic pain and/or neuropathic pain and migraines |
| EP1309324B1 (en) * | 2000-07-07 | 2006-03-22 | Ortho-McNeil Pharmaceutical, Inc. | Anticonvulsant derivatives useful for treating and preventing the development of type ii diabetes mellitus and syndrome x |
| DE10035227A1 (de) * | 2000-07-20 | 2002-01-31 | Solvay Pharm Gmbh | Verfahren zum Auffinden von Verbindungen, welche zur Behandlung und/oder Prophylaxe von Fettleibigkeit geeignet sind |
| US6946243B2 (en) * | 2000-07-20 | 2005-09-20 | Solvay Pharmaceuticals Gmbh | Method of identifying compounds suitable for treatment and/or prophylaxis of obesity |
| US6627653B2 (en) * | 2000-08-02 | 2003-09-30 | Ortho-Mcneil Pharmaceutical, Inc. | Anticonvulsant derivatives useful for the treatment of depression |
| US7256184B2 (en) * | 2000-10-16 | 2007-08-14 | Rodriguez Victorio C | Treatment of aging disorders in humans |
| EP1357908A4 (en) * | 2001-01-30 | 2009-07-15 | Merck & Co Inc | "ACYLSULFAMIDES FOR THE TREATMENT OF FATIBILITY, DIABETES AND LIPID DISORDERS" |
| JP2004536071A (ja) | 2001-05-25 | 2004-12-02 | クイーンズ ユニバーシティ アット キングストン | 複素環ベータアミノ酸およびそれらの抗癲癇誘発剤としての使用 |
| US6559293B1 (en) * | 2002-02-15 | 2003-05-06 | Transform Pharmaceuticals, Inc. | Topiramate sodium trihydrate |
| US8637512B2 (en) * | 2002-07-29 | 2014-01-28 | Glaxo Group Limited | Formulations and method of treatment |
| RU2226357C1 (ru) | 2003-02-12 | 2004-04-10 | Санкт-Петербургский научно-исследовательский психоневрологический институт им. В.М.Бехтерева | Способ диагностики эпилепсии у пациентов с доклинической стадией болезни |
| RU2246727C2 (ru) | 2003-02-12 | 2005-02-20 | Санкт-Петербургский научно-исследовательский психоневрологический институт им. В.М. Бехтерева (НИПИ) | Способ диагностики доклинической стадии эпилепсии |
| AU2004231070B2 (en) | 2003-04-10 | 2008-02-14 | Amgen, Inc. | Bicyclic compounds having bradykinin receptors affinity and pharmaceutical compositions thereof |
| EP1615629B1 (en) | 2003-04-16 | 2009-03-18 | Smithkline Beecham Corporation | Peptide deformylase inhibitors |
| WO2004093912A1 (ja) | 2003-04-23 | 2004-11-04 | Kyowa Hakko Kogyo Co. Ltd. | 好中球性炎症疾患の予防および/または治療剤 |
| GB0309781D0 (en) | 2003-04-29 | 2003-06-04 | Glaxo Group Ltd | Compounds |
| US6949518B1 (en) * | 2003-06-25 | 2005-09-27 | Pao-Hsien Chu | Methods for treating macular degeneration with topiramate |
| JP2007504228A (ja) | 2003-09-02 | 2007-03-01 | メルク エンド カムパニー インコーポレーテッド | 高眼圧症を治療するための眼組成物 |
| CN1897950A (zh) * | 2003-10-14 | 2007-01-17 | 惠氏公司 | 稠合芳基和杂芳基衍生物及其使用方法 |
| MY147767A (en) * | 2004-06-16 | 2013-01-31 | Janssen Pharmaceutica Nv | Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders |
| TW200612905A (en) * | 2004-06-16 | 2006-05-01 | Janssen Pharmaceutica Nv | Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders |
| EP1776106B1 (en) | 2004-06-22 | 2013-08-07 | Vertex Pharmaceuticals Incorporated | Heterocyclic derivatives for modulation of calcium channels |
| NZ552865A (en) | 2004-07-28 | 2009-09-25 | Janssen Pharmaceutica Nv | Substituted indolyl alkyl amino derivatives as novel inhibitors of histone deacetylase |
| US20060276528A1 (en) * | 2004-08-24 | 2006-12-07 | Abdel-Magid Ahmed F | Novel benzo-fused heteroaryl sulfamide derivatives useful as anticonvulsant agents |
| ES2310366T3 (es) | 2004-08-24 | 2009-01-01 | Janssen Pharmaceutica Nv | Nuevos derivados de heteroaril sulfonamida benzo-condensada utiles como agentes anticonvulsivos. |
| GT200600159A (es) * | 2005-04-22 | 2007-03-14 | Derivados benzodioxano y benzodioxolano y usos de los mismos | |
| JP2008545650A (ja) * | 2005-05-20 | 2008-12-18 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | スルファミド誘導体の製造方法 |
| US8492431B2 (en) | 2005-12-19 | 2013-07-23 | Janssen Pharmaceutica, N.V. | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of obesity |
| US20070155824A1 (en) * | 2005-12-19 | 2007-07-05 | Smith-Swintosky Virginia L | Use of benzo-fused heterocycle sulfamide derivatives for disease modification / epileptogenesis |
| TW200812574A (en) * | 2006-05-19 | 2008-03-16 | Janssen Pharmaceutica Nv | Co-therapy for the treatment of epilepsy and related disorders |
| WO2007137167A2 (en) * | 2006-05-19 | 2007-11-29 | Janssen Pharmaceutica N.V. | Co-therapy for the treatment of epilepsy |
| WO2008061903A1 (en) * | 2006-11-22 | 2008-05-29 | Agfa Healthcate Inc. | Method and system for client / server distributed image processing |
| US20090182141A1 (en) * | 2008-01-07 | 2009-07-16 | Ahmed Abdel-Magid | Process for the preparation of sulfamide derivatives |
| US20090247618A1 (en) * | 2008-03-26 | 2009-10-01 | Ballentine Scott A | Process for preparation of benzo-fused heteroaryl derivatives |
| US20090247617A1 (en) * | 2008-03-26 | 2009-10-01 | Abdel-Magid Ahmed F | Process for the preparation of benzo-fused heteroaryl sulfamates |
| PE20110060A1 (es) * | 2008-06-23 | 2011-01-31 | Janssen Pharmaceutica Nv | Forma cristalina de (2s)-(-)-n-(6-cloro-2,3-dihidro-benzo[1,4]dioxin-2-ilmetil)-sulfamida |
-
2006
- 2006-12-18 US US11/611,938 patent/US8492431B2/en not_active Expired - Fee Related
- 2006-12-18 AR ARP060105591A patent/AR058389A1/es not_active Application Discontinuation
- 2006-12-19 UY UY30033A patent/UY30033A1/es unknown
- 2006-12-19 SI SI200631151T patent/SI1968574T1/sl unknown
- 2006-12-19 ES ES06847860T patent/ES2369761T3/es active Active
- 2006-12-19 PL PL06847860T patent/PL1968574T3/pl unknown
- 2006-12-19 AT AT06847860T patent/ATE519484T1/de active
- 2006-12-19 JP JP2008547519A patent/JP5190378B2/ja not_active Expired - Fee Related
- 2006-12-19 HR HRP20110726TT patent/HRP20110726T2/hr unknown
- 2006-12-19 EA EA200870093A patent/EA016560B1/ru not_active IP Right Cessation
- 2006-12-19 CA CA2634093A patent/CA2634093C/en not_active Expired - Fee Related
- 2006-12-19 MY MYPI20082188A patent/MY145823A/en unknown
- 2006-12-19 CN CN2006800524528A patent/CN101365442B/zh not_active Expired - Fee Related
- 2006-12-19 PE PE2006001639A patent/PE20070813A1/es not_active Application Discontinuation
- 2006-12-19 RS RS20110496A patent/RS52044B/sr unknown
- 2006-12-19 PT PT06847860T patent/PT1968574E/pt unknown
- 2006-12-19 DK DK06847860.1T patent/DK1968574T3/da active
- 2006-12-19 ME MEP-2011-166A patent/ME01344B/me unknown
- 2006-12-19 AU AU2006331637A patent/AU2006331637B2/en not_active Ceased
- 2006-12-19 BR BRPI0620019-2A patent/BRPI0620019A2/pt not_active IP Right Cessation
- 2006-12-19 NZ NZ568960A patent/NZ568960A/en not_active IP Right Cessation
- 2006-12-19 EP EP06847860A patent/EP1968574B9/en active Active
- 2006-12-19 KR KR1020087017531A patent/KR101363308B1/ko not_active Expired - Fee Related
- 2006-12-19 WO PCT/US2006/048681 patent/WO2007075833A2/en not_active Ceased
-
2008
- 2008-06-12 IL IL192107A patent/IL192107A/en not_active IP Right Cessation
- 2008-06-19 SV SV2008002952A patent/SV2008002952A/es unknown
- 2008-07-03 NO NO20083006A patent/NO20083006L/no not_active Application Discontinuation
- 2008-07-18 ZA ZA200806279A patent/ZA200806279B/xx unknown
- 2008-07-21 CR CR10164A patent/CR10164A/es not_active Application Discontinuation
-
2011
- 2011-11-09 CY CY20111101079T patent/CY1112357T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SV2008002952A (es) | Uso de derivados de sulfamida heterociclica benzo-fusionada para el tratamiento de obesidad referencia cruzada a solicitudes relacionadas ref. prd2586sv | |
| CL2008003222A1 (es) | Peptidos con actividad antagonista de glucagon y composicion farmaceutica que los comprende, utiles para el tratamiento de la hiperglicemia, para suprimir el apetito, reducir el aumento de peso y para tratar el desgaste catabolico. | |
| CL2008001879A1 (es) | Compuestos derivados de isaxolinas-naftalen-carboamida; y el uso de los compuestos en el control de plagas de invertebrados en animales. | |
| PA8772101A1 (es) | Imidazol-triazolopirimidinas sustituidas | |
| UY32659A (es) | Pirazinilpirazoles | |
| GT200500363A (es) | 3-amino-pirazol [3,4b] piridinas con inhibidores de proteintirosinquinasas, su preparacion y uso como medicamento. | |
| NI201000044A (es) | Bromhidrato de bupropión y aplicaciones terapéuticas | |
| GT200600046A (es) | Terapia de combinacion | |
| CR20110609A (es) | Composicion antimicrobiana y metodos relacionados de uso | |
| TW200740956A (en) | Organic electroluminescent devices | |
| CL2011000846A1 (es) | Compuestos heterociclicos sustituidos; composicion farmaceutica; y su uso para el tratamiento de la hepatitis c. | |
| CL2008003847A1 (es) | Compuestos derivados de 6-fenilpirazin-2-carboxamida y 6-fenilpirazin-2-carbotioamida, inhibidores de dgat-1; composicion farmaceutica; y su uso en el tratamiento de la diabetes mellitus y obesidad. | |
| CL2007003726A1 (es) | Anticuerpos anti-receptor del factor del crecimiento similar a la insulina i (igf-ir); composicion farmaceutica que lo contiene; y su uso para tratar el cancer. | |
| GT201000047A (es) | Mejoras en compuestos organicos o relacionadas con los mismos | |
| PA8779801A1 (es) | Derivados heterocíclicos sustituidos y su uso farmacéutico y composiciones | |
| CL2008002049A1 (es) | Compuestos derivados de aminoindol macrociclicos; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento de la hepatitis c. | |
| BRPI0808798A2 (pt) | Fenoxifenilamidinas 3,5-dissubstituídas e seu uso como fungicidas | |
| CL2008003546A1 (es) | Compuestos derivados de piridina; procedimiento de preparacion; composicion farmaceutica de dichos compuestos; y uso en el tratamiento y/o profilaxis de la diabetes mellitus tipo i y/o tipo ii. | |
| CL2007003672A1 (es) | Compuestos derivados de heteroaril-pirrolidinil-cetona y heteroaril-piperidinil-cetona; composicion farmaceutica; y uso en el tratamiento de la depresion y ansiedad. | |
| CR11259A (es) | Bromhidrato de bupropion y aplicaciones terapueticas | |
| AR053803A1 (es) | Uso de acido pinolenico | |
| CL2009000665A1 (es) | Compuestos derivados de pirrolidinilo; composicion farmaceutica que comprende a dichos compuestos; y su uso en el tratamiento de la ansiedad, depresion o ambas. | |
| UY30214A1 (es) | Modificaciones de ( 5s) -5-(4-(5-cloro-piridin--2-iloxi)-piperidina-1-sulfonilmetil)-5-metil-imidazolidina-2,4-diona, procesos para su preparacion, composiciones que los contengan y aplicaciones. | |
| CL2012003710A1 (es) | Material celulosico que tiene uno o mas diluyentes del humo dentro de su estructura celular en que el peso de dicho diluyente del humo es mayor o igual al 5 % en base al peso seco del material celulosico; metodo de preparacion de dicho material, y su uso. | |
| CL2012001757A1 (es) | Compuestos derivados de 8-hidroxiquinolina-7-carboxamida; composicion farmaceutica; y su uso en el tratamiento de infecciones micoticas. |