SU30153A1 - The method of obtaining soluble organic complex compounds of antimony - Google Patents
The method of obtaining soluble organic complex compounds of antimonyInfo
- Publication number
- SU30153A1 SU30153A1 SU57672A SU57672A SU30153A1 SU 30153 A1 SU30153 A1 SU 30153A1 SU 57672 A SU57672 A SU 57672A SU 57672 A SU57672 A SU 57672A SU 30153 A1 SU30153 A1 SU 30153A1
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- antimony
- soluble organic
- complex compounds
- organic complex
- acid
- Prior art date
Links
- 229910052787 antimony Inorganic materials 0.000 title description 8
- WATWJIUSRGPENY-UHFFFAOYSA-N antimony atom Chemical compound [Sb] WATWJIUSRGPENY-UHFFFAOYSA-N 0.000 title description 8
- 150000001875 compounds Chemical class 0.000 title description 4
- 238000000034 method Methods 0.000 title description 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 9
- 239000002253 acid Substances 0.000 description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 7
- 150000003839 salts Chemical class 0.000 description 5
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 229940058905 antimony compound for treatment of leishmaniasis and trypanosomiasis Drugs 0.000 description 3
- 150000001463 antimony compounds Chemical class 0.000 description 3
- CJAZCKUGLFWINJ-UHFFFAOYSA-N 3,4-dihydroxybenzene-1,2-disulfonic acid Chemical compound OC1=CC=C(S(O)(=O)=O)C(S(O)(=O)=O)=C1O CJAZCKUGLFWINJ-UHFFFAOYSA-N 0.000 description 2
- 125000003118 aryl group Chemical group 0.000 description 2
- LNTHITQWFMADLM-UHFFFAOYSA-N gallic acid Chemical compound OC(=O)C1=CC(O)=C(O)C(O)=C1 LNTHITQWFMADLM-UHFFFAOYSA-N 0.000 description 2
- 238000006386 neutralization reaction Methods 0.000 description 2
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 description 2
- WQGWDDDVZFFDIG-UHFFFAOYSA-N pyrogallol Chemical compound OC1=CC=CC(O)=C1O WQGWDDDVZFFDIG-UHFFFAOYSA-N 0.000 description 2
- GLDQAMYCGOIJDV-UHFFFAOYSA-N 2,3-dihydroxybenzoic acid Chemical compound OC(=O)C1=CC=CC(O)=C1O GLDQAMYCGOIJDV-UHFFFAOYSA-N 0.000 description 1
- BFSVOASYOCHEOV-UHFFFAOYSA-N 2-diethylaminoethanol Chemical compound CCN(CC)CCO BFSVOASYOCHEOV-UHFFFAOYSA-N 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- UEEJHVSXFDXPFK-UHFFFAOYSA-N N-dimethylaminoethanol Chemical compound CN(C)CCO UEEJHVSXFDXPFK-UHFFFAOYSA-N 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 150000001462 antimony Chemical class 0.000 description 1
- -1 antimony diethylaminoethanol Chemical compound 0.000 description 1
- 239000012736 aqueous medium Substances 0.000 description 1
- 229960002887 deanol Drugs 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 231100000502 fertility decrease Toxicity 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 229940074391 gallic acid Drugs 0.000 description 1
- 235000004515 gallic acid Nutrition 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 229940079877 pyrogallol Drugs 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Description
Было найдено, что можно получить растворимые органические соединени сурьмы, обладающие большим терапевтическим действием при сильно пониженной довитости.It was found that it is possible to obtain soluble organic antimony compounds having a high therapeutic effect with greatly reduced fertility.
Cnocoi5 получени соединений сурьмы состоит в том, что на ароматические о-диоксисоединени с кислыми солеобразующими заместител ми действуют п тивалентными соединени ми сурьмы. Образовавшиес комплексные соли в каждом данном случае выдел ютс после нейтрализации основными веществами.Cnocoi5 for the preparation of antimony compounds consists in the fact that aromatic o-dioxo compounds with acid salt-forming substitutes are affected by pyvalent antimony compounds. In each of these cases, the resulting complex salts are isolated after neutralization with basic substances.
Пример 1. - 20 I калийной соли пирокатехиндисульфокислого кали раствор ют в 100 куб. см воды и раствор нагревают с избыточной сурьм ной кислотой (лучше всего в свеже осажденном состо нии). Дают остыть, отфильтровывают нерастворимый остаток, нейтрализуют фильтрат разбавленным едким кали и осаждают выливанием в метиловый спирт. Получают бесцветный порошок , легко растворимый в воде.Example 1. - 20 I potassium salt of potassium catechol disulfonic acid is dissolved in 100 cubic meters. cm of water and the solution is heated with excess antimony acid (preferably in a freshly precipitated state). The mixture is allowed to cool, the insoluble residue is filtered off, the filtrate is neutralized with dilute potassium hydroxide and precipitated by pouring into methyl alcohol. A colorless powder readily soluble in water is obtained.
(297)(297)
Пример 2. - Раствор ют 10 г сурь м нокислого диэтиламиноэтанола в 15 куб. см воды, равным образом 14,5 z калийной соли дисульфопирогаллоловой кислоты в 30 куб. см воды при подогреве . Оба раствора соедин ют, нейтрализуют разбавленным раствором диэтиламиноэтанола , раствор упариваетс или же образовавша с комплексна соль сурьмы осаждаетс вливанием в метиловый спирт. При изменении отношени масс в примере 2 можно получить, напр., комплексную соль с более низким содержанием сурьмы.Example 2. - Dissolve 10 g of dimethylaminoethanol in 15 cu. cm of water, as well as 14.5 z of the potassium salt of disulfopirogallic acid in 30 cubic meters. cm of water when heated. Both solutions are combined, neutralized with a dilute solution of diethylaminoethanol, the solution is evaporated, or the complex antimony salt formed with the precipitate is poured into methyl alcohol. By changing the ratio of the masses in example 2, it is possible to obtain, for example, a complex salt with a lower content of antimony.
Аналогичным образом могут быть получены, напр., комплексные соли п тивалентной сурьмы с пирокатехиндисульфокислотой , пирокатехинкарбоновой кислотой , ализаринсульфокислотой, галловой кислотой и т. д.Similarly, for example, complex salts of pivalent antimony with pyrocatechol disulfonic acid, pyrocatechol carboxylic acid, alizarinsulfonic acid, gallic acid, etc. can be obtained.
Пример 3.-К раствору 100 i пирогаллолдисульфокислого натри в 300 куб. см воды прибавл етс взмученна в воде сурьм на кислота, свеже полученна Example 3.-To a solution of 100 i sodium pyrogallol disulfonic acid in 300 cu. cm of water added antimony acid stirred up in water, freshly obtained
из 100 г п тихлористой сурьмы. При нагревании на вод ной бане вскоре происходит растворение. Отфильтровывают небольшую муть, добавл ют разбавленного едкого натра почти до нейтрализации , концентрируют раствор и осаждают образовавшуюс комплексную соль вливанием в метиловый спирт.from 100 g of pichlorium antimony. When heated in a water bath, dissolution soon occurs. A small slurry is filtered off, dilute sodium hydroxide is added almost to neutralization, the solution is concentrated and the complex salt formed is precipitated by pouring it into methyl alcohol.
Предметпатента.Subject patent.
1. Способ получени растворимых органических комплексных соединений1. The method of obtaining soluble organic complex compounds
сурьмы, отличающийс тем, что ароматические ортодиоксисульфоновь1е или ортодиоксикарбоновые кислоты обрабатывают в водной среде сурьм ной кислотой или сурьм нокислым диэтиламиноэтанолом в присутствии оснований или без Них.Antimony, characterized in that aromatic orthodioxysulfonic or orthodioxycarboxylic acids are treated with antimony acid or antimony diethylaminoethanol in an aqueous medium with or without bases.
2. Видоизменение способа согласно п. 1, отличающеес тем, что с целью получени нейтральных растворимых солей означенные комплексные соединени нейтрализуют основани ми.2. Modification of the method according to claim 1, characterized in that in order to obtain neutral soluble salts, the said complex compounds are neutralized with bases.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU57672A SU30153A1 (en) | 1929-11-04 | 1929-11-04 | The method of obtaining soluble organic complex compounds of antimony |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU57672A SU30153A1 (en) | 1929-11-04 | 1929-11-04 | The method of obtaining soluble organic complex compounds of antimony |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU30153A1 true SU30153A1 (en) | 1933-04-30 |
Family
ID=48347761
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU57672A SU30153A1 (en) | 1929-11-04 | 1929-11-04 | The method of obtaining soluble organic complex compounds of antimony |
Country Status (1)
| Country | Link |
|---|---|
| SU (1) | SU30153A1 (en) |
-
1929
- 1929-11-04 SU SU57672A patent/SU30153A1/en active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SU30153A1 (en) | The method of obtaining soluble organic complex compounds of antimony | |
| Hubacher | The preparation of 2-(4-Hydroxybenzoyl)-benzoic acid | |
| SU21905A1 (en) | Method of producing para-aminophenylstibic acid salts | |
| SU17206A1 (en) | The method of obtaining salts of quinine or cinchonin with 3-acetyl-amino-4-hydroxyphenylarsinic acid | |
| SU26668A1 (en) | The method of preparation hinaldia | |
| SU30152A1 (en) | The method of obtaining complex salts of antimony | |
| DE397313C (en) | Process for the preparation of sulfonic acids of the 2íñ3-Oxynaphthoesaeurearylide | |
| SU6661A1 (en) | The method of obtaining neutral reactive water soluble derivatives of diaminodioxy-arsenobenzene | |
| SU24501A1 (en) | Method of making carcass | |
| DE601896C (en) | Process for the sulfonation of N-substituted 2-pyridones | |
| SU41950A1 (en) | Method for producing water soluble calcium glycerophosphate | |
| SU3264A1 (en) | The method of preparation of hydrochloric diacetylmorphine | |
| SU44205A1 (en) | Method for preparing dinitrostilbendisulfonic acid | |
| SU101715A1 (en) | Method for preparing usnic acid sodium salt | |
| SU521877A1 (en) | Method for the production of jelly confectionery | |
| AT117232B (en) | Process for the preparation of salts of antimonic acid and its derivatives. | |
| SU24380A1 (en) | The method of preparation of the detergent preparation | |
| PL14367B1 (en) | The method of obtaining a readily soluble salt of 3-acetylamino-4-oxy-benzenarsinic acid. | |
| DE661750C (en) | Process for the preparation of gold compounds from keratin breakdown products | |
| SU15609A1 (en) | The method of obtaining organic compounds of bismuth | |
| DE73267C (en) | Process for the preparation of thiodioxydiphenylmethanesulfonic acids | |
| DE555680C (en) | Process for the preparation of salts of antimonic acid and their derivatives | |
| SU14629A1 (en) | Method for producing mouse co-sodium salt | |
| SU38419A1 (en) | Method of making refractory boxes for storing films | |
| GB410152A (en) | Improvements in or relating to the manufacture of solutions of cellulose derivativesor conversion products |