SMT201400079B - Produzione di poliovirus ad alti titoli per la produzione di vaccino - Google Patents

Produzione di poliovirus ad alti titoli per la produzione di vaccino

Info

Publication number: SMT201400079B
Authority: SM; San Marino
Prior art keywords: production; poliovirus; high titers; vaccine; vaccine production
Prior art date: 2009-07-16

Application number

SM201400079T

Other languages

English (en)

Italian (it)

Inventor

John Alfred Lewis

Original Assignee

Crucell Holland Bv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-07-16

Filing date

2014-06-24

Publication date

2014-09-08

2014-06-24 Application filed by Crucell Holland Bv filed Critical Crucell Holland Bv

2014-09-08 Publication of SMT201400079B publication Critical patent/SMT201400079B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/02—Recovery or purification
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/125—Picornaviridae, e.g. calicivirus
- A61K39/13—Poliovirus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32611—Poliovirus
- C12N2770/32634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32611—Poliovirus
- C12N2770/32651—Methods of production or purification of viral material
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Virology (AREA)
General Health & Medical Sciences (AREA)
Immunology (AREA)
Medicinal Chemistry (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Microbiology (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
Wood Science & Technology (AREA)
Biomedical Technology (AREA)
Epidemiology (AREA)
Mycology (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Molecular Biology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

SM201400079T 2009-07-16 2014-06-24 Produzione di poliovirus ad alti titoli per la produzione di vaccino SMT201400079B (it)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US27103809P	2009-07-16	2009-07-16
EP09165620		2009-07-16
EP10729895.2A EP2454364B1 (en)	2009-07-16	2010-07-08	Production of polio virus at high titers for vaccine production
PCT/EP2010/059796 WO2011006823A1 (en)	2009-07-16	2010-07-08	Production of polio virus at high titers for vaccine production

Publications (1)

Publication Number	Publication Date
SMT201400079B true SMT201400079B (it)	2014-09-08

Family

ID=41412431

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SM201400079T SMT201400079B (it)	2009-07-16	2014-06-24	Produzione di poliovirus ad alti titoli per la produzione di vaccino

Country Status (32)

Country	Link
US (4)	US8546123B2 (es)
EP (1)	EP2454364B1 (es)
JP (1)	JP5845178B2 (es)
KR (1)	KR101548790B1 (es)
CN (1)	CN102482647B (es)
AP (1)	AP3140A (es)
AR (1)	AR077314A1 (es)
AU (1)	AU2010272685B2 (es)
BR (1)	BR112012000942B8 (es)
CA (1)	CA2763091C (es)
CO (1)	CO6491042A2 (es)
CU (1)	CU20120006A7 (es)
DK (1)	DK2454364T3 (es)
EA (1)	EA020563B1 (es)
ES (1)	ES2484093T3 (es)
HR (1)	HRP20140597T1 (es)
IL (1)	IL217465A (es)
MA (1)	MA33429B1 (es)
MX (1)	MX2011012648A (es)
MY (1)	MY183385A (es)
NZ (1)	NZ596880A (es)
PE (1)	PE20120571A1 (es)
PL (1)	PL2454364T3 (es)
PT (1)	PT2454364E (es)
RS (1)	RS53377B (es)
SG (1)	SG177655A1 (es)
SI (1)	SI2454364T1 (es)
SM (1)	SMT201400079B (es)
TN (1)	TN2011000628A1 (es)
TW (1)	TWI477606B (es)
WO (1)	WO2011006823A1 (es)
ZA (1)	ZA201108271B (es)

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NZ593235A (en)	2008-11-03	2013-02-22	Crucell Holland Bv	Method for the production of recombinant adenovirus serotype 35
MA33429B1 (fr) *	2009-07-16	2012-07-03	Crucell Holland Bv	Production de poliovirus à titres élevés pour la production de vaccins
JP2013507990A (ja)	2009-10-26	2013-03-07	ダブリュエーアールエフ−ウィスコンシンアラムナイリサーチファウンデーション	ベロ細胞において増強された複製を有する高力価の組換えインフルエンザウイルス
US10130697B2 (en)	2010-03-23	2018-11-20	Wisconsin Alumni Research Foundation (Warf)	Vaccines comprising mutant attenuated influenza viruses
JP2014527799A (ja)	2011-08-26	2014-10-23	ダブリュエーアールエフ−ウィスコンシンアラムナイリサーチファウンデーション	変異型ｐｂ２遺伝子セグメントを有する弱毒化生ワクチンとしてのインフルエンザウイルス
BR112015018493A2 (pt) *	2013-02-05	2017-08-22	Univ Georgia	Linhagens celulares para produção de vírus e métodos de uso
KR102236498B1 (ko)	2013-03-08	2021-04-06	얀센 백신스 앤드 프리벤션 비.브이.	무세포 백일해 백신
WO2014142433A1 (ko)	2013-03-13	2014-09-18	고려대학교산학협력단	바이러스 생산능이 증가된 세포주 및 그 제조방법
KR20140112255A (ko)	2013-03-13	2014-09-23	고려대학교 산학협력단	바이러스 생산능이 증가된 세포주 및 그 제조방법
GB201305361D0 (en)	2013-03-25	2013-05-08	Univ Edinburgh	Enhanced expression
ES2689150T3 (es)	2013-06-17	2018-11-08	De Staat Der Nederlanden, Vert. Door De Minister Van Vws, Ministerie Van Volksgezondheid, Welzijn En Sport	Métodos para la prevención de agregación de componentes víricos
US9950057B2 (en)	2013-07-15	2018-04-24	Wisconsin Alumni Research Foundation (Warf)	High titer recombinant influenza viruses with enhanced replication in MDCK or vero cells or eggs
US20160053281A1 (en) *	2013-08-15	2016-02-25	The University Court Of The University Of Edinburgh	Enhanced Expression Of RNA Vectors
EP3613841B1 (en)	2014-03-25	2022-04-20	Terumo BCT, Inc.	Passive replacement of media
KR102423993B1 (ko)	2014-06-17	2022-07-22	얀센 백신스 앤드 프리벤션 비.브이.	저온-적응-바이러스-약독화(cava) 및 신규의 약독화 폴리오바이러스 균주
JP6708636B2 (ja)	2014-06-18	2020-06-10	イミュノマックスカンパニーリミテッドＩｍｍｕｎｏｍａｘＣｏ．，Ｌｔｄ．	Ｂｓｔ２遺伝子の機能が喪失された細胞株を利用したウィルス感染促進及び産生増進方法
US10053671B2 (en)	2014-06-20	2018-08-21	Wisconsin Alumni Research Foundation (Warf)	Mutations that confer genetic stability to additional genes in influenza viruses
DK3172317T3 (da)	2014-07-24	2019-07-22	Janssen Vaccines & Prevention Bv	Fremgangsmåde til oprensning af poliovirus fra cellekulturer
US10633422B2 (en)	2015-06-01	2020-04-28	Wisconsin Alumni Research Foundation (Warf)	Influenza virus replication by inhibiting microRNA lec7C binding to influenza viral cRNA and mRNA
WO2017004592A1 (en)	2015-07-02	2017-01-05	Terumo Bct, Inc.	Cell growth with mechanical stimuli
US9890363B2 (en)	2015-07-06	2018-02-13	Wisconsin Alumni Research Foundation (Warf)	Influenza virus replication for vaccine development
WO2017143236A1 (en)	2016-02-19	2017-08-24	Yoshihiro Kawaoka	Improved influenza b virus replication for vaccine development
CN109415696A (zh)	2016-05-25	2019-03-01	泰尔茂比司特公司	细胞扩增
US11685883B2 (en)	2016-06-07	2023-06-27	Terumo Bct, Inc.	Methods and systems for coating a cell growth surface
US11104874B2 (en)	2016-06-07	2021-08-31	Terumo Bct, Inc.	Coating a bioreactor
US10372100B2 (en) *	2016-08-29	2019-08-06	Ge Healthcare Bio-Sciences Corp.	Manufacturing system for biopharmaceutical products
CN110612344B (zh)	2017-03-31	2023-09-12	泰尔茂比司特公司	细胞扩增
CN107723279B (zh) *	2017-10-18	2020-11-10	成都远睿生物技术有限公司	一种缺陷型腺病毒AdC68-GP的培养方法
JP2021500891A (ja)	2017-10-25	2021-01-14	ウィスコンシンアルムニリサーチファンデイション	卵における複製のための安定化されたｈａを有する組換えインフルエンザウイルス
SG11202007503WA (en)	2018-02-07	2020-09-29	Bharat Biotech Int Ltd	A process for enterovirus purification and inactivation and vaccine compositions obtained thereof
JP7783047B2 (ja)	2018-08-07	2025-12-09	ウィスコンシンアルムニリサーチファンデイション	組換えの生物学的に封じ込められたフィロウイルスワクチン
US11389523B2 (en)	2018-08-20	2022-07-19	Wisconsin Alumni Research Foundation (Warf)	Vectors for eliciting immune responses to non-dominant epitopes in the hemagglutinin (HA) protein
EP3914295A2 (en)	2019-01-23	2021-12-01	Yoshihiro Kawaoka	Mutations that confer genetic stability to additional genes in influenza viruses
CN113874496A (zh)	2019-02-08	2021-12-31	威斯康星校友研究基金会(Warf)	人源化细胞系
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2010
- 2010-07-08 MA MA34534A patent/MA33429B1/fr unknown
- 2010-07-08 MX MX2011012648A patent/MX2011012648A/es active IP Right Grant
- 2010-07-08 PT PT107298952T patent/PT2454364E/pt unknown
- 2010-07-08 BR BR112012000942A patent/BR112012000942B8/pt not_active IP Right Cessation
- 2010-07-08 EP EP10729895.2A patent/EP2454364B1/en active Active
- 2010-07-08 JP JP2012519981A patent/JP5845178B2/ja not_active Expired - Fee Related
- 2010-07-08 DK DK10729895.2T patent/DK2454364T3/da active
- 2010-07-08 CN CN201080026814.2A patent/CN102482647B/zh not_active Expired - Fee Related
- 2010-07-08 RS RS20140325A patent/RS53377B/sr unknown
- 2010-07-08 KR KR1020127001501A patent/KR101548790B1/ko not_active Expired - Fee Related
- 2010-07-08 ES ES10729895.2T patent/ES2484093T3/es active Active
- 2010-07-08 PE PE2012000051A patent/PE20120571A1/es active IP Right Grant
- 2010-07-08 HR HRP20140597AT patent/HRP20140597T1/hr unknown
- 2010-07-08 WO PCT/EP2010/059796 patent/WO2011006823A1/en not_active Ceased
- 2010-07-08 AU AU2010272685A patent/AU2010272685B2/en not_active Ceased
- 2010-07-08 AP AP2012006075A patent/AP3140A/xx active
- 2010-07-08 SI SI201030661T patent/SI2454364T1/sl unknown
- 2010-07-08 MY MYPI2012000173A patent/MY183385A/en unknown
- 2010-07-08 NZ NZ596880A patent/NZ596880A/xx not_active IP Right Cessation
- 2010-07-08 EA EA201270173A patent/EA020563B1/ru not_active IP Right Cessation
- 2010-07-08 SG SG2012002705A patent/SG177655A1/en unknown
- 2010-07-08 CA CA2763091A patent/CA2763091C/en active Active
- 2010-07-08 PL PL10729895T patent/PL2454364T3/pl unknown
- 2010-07-14 AR ARP100102556A patent/AR077314A1/es active IP Right Grant
- 2010-07-15 TW TW099123327A patent/TWI477606B/zh not_active IP Right Cessation
- 2010-07-16 US US12/804,242 patent/US8546123B2/en not_active Expired - Fee Related
2011
- 2011-11-10 ZA ZA2011/08271A patent/ZA201108271B/en unknown
- 2011-12-07 TN TNP2011000628A patent/TN2011000628A1/en unknown
2012
- 2012-01-10 IL IL217465A patent/IL217465A/en active IP Right Grant
- 2012-01-13 CU CU2012000006A patent/CU20120006A7/es unknown
- 2012-01-16 CO CO12005515A patent/CO6491042A2/es unknown
- 2012-10-25 US US13/660,412 patent/US20130052224A1/en not_active Abandoned
2013
- 2013-03-15 US US13/843,052 patent/US20130273106A1/en not_active Abandoned
2014
- 2014-05-12 US US14/275,392 patent/US9022240B2/en active Active
- 2014-06-24 SM SM201400079T patent/SMT201400079B/xx unknown

Also Published As

Publication number	Publication date
AU2010272685A1 (en)	2011-12-08
CU20120006A7 (es)	2012-10-15
SI2454364T1 (sl)	2014-08-29
US20140242670A1 (en)	2014-08-28
TW201118173A (en)	2011-06-01
AU2010272685B2 (en)	2015-02-26
CO6491042A2 (es)	2012-07-31
CA2763091C (en)	2019-07-23
ZA201108271B (en)	2012-07-25
MA33429B1 (fr)	2012-07-03
US8546123B2 (en)	2013-10-01
CA2763091A1 (en)	2011-01-20
TWI477606B (zh)	2015-03-21
JP5845178B2 (ja)	2016-01-20
HRP20140597T1 (hr)	2014-09-12
US20110027317A1 (en)	2011-02-03
PE20120571A1 (es)	2012-06-06
PT2454364E (pt)	2014-07-04
CN102482647B (zh)	2015-12-16
BR112012000942A2 (pt)	2016-03-15
DK2454364T3 (da)	2014-07-21
EA020563B1 (ru)	2014-12-30
KR101548790B1 (ko)	2015-08-31
RS53377B (sr)	2014-10-31
US20130052224A1 (en)	2013-02-28
IL217465A (en)	2016-05-31
AP3140A (en)	2015-02-28
US20130273106A1 (en)	2013-10-17
AP2012006075A0 (en)	2012-02-29
BR112012000942B1 (pt)	2020-10-27
US9022240B2 (en)	2015-05-05
JP2012532616A (ja)	2012-12-20
EP2454364A1 (en)	2012-05-23
PL2454364T3 (pl)	2014-09-30
SG177655A1 (en)	2012-02-28
ES2484093T3 (es)	2014-08-11
HK1164922A1 (en)	2012-09-28
TN2011000628A1 (en)	2013-05-24
IL217465A0 (en)	2012-02-29
EA201270173A1 (ru)	2012-06-29
BR112012000942B8 (pt)	2021-05-25
AR077314A1 (es)	2011-08-17
NZ596880A (en)	2013-10-25
CN102482647A (zh)	2012-05-30
KR20120033334A (ko)	2012-04-06
WO2011006823A1 (en)	2011-01-20
MX2011012648A (es)	2012-01-12
MY183385A (en)	2021-02-18
EP2454364B1 (en)	2014-04-23

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SMT201600254B (it)	2016-08-31	Procedimento per la preparazione di idromagnesite
DK2414531T3 (da)	2021-06-21	Forbedret biomasseforbehandlingsproces
EP2498844A4 (en)	2013-10-09	IMPFSPRITZE
EP2490701A4 (en)	2013-09-25	Cardiomyocyte production
EP2475761A4 (en)	2015-04-22	PHOTO BIOREACTOR
SI2496562T1 (sl)	2014-06-30	Postopek priprave kalkobutrola
EP2408473A4 (en)	2013-02-13	seeding method
BRPI1012606A2 (pt)	2017-01-24	exposição multivalente de adjuvante
SMT201500268B (it)	2016-01-08	Derivato di 5-idrossipirimidin-4-carbossammide
BRPI1009018A2 (pt)	2015-12-01	fotobiorreator
ITMI20100141A1 (it)	2010-08-10	Disposizione di sensori
GB0918679D0 (en)	2009-12-09	Influenza vaccine
BRPI0916732A2 (pt)	2017-01-31	vacina contra hpv
EP2543387A4 (en)	2013-06-19	MUCOSA VACCINE
BRPI1014031A2 (pt)	2018-02-20	vacinas de nanoemulsão
IT1397503B1 (it)	2013-01-16	Processo per la preparazione di olopatadina
EP2498815A4 (en)	2014-03-19	VACCINE COMPOSITION
SI2482845T1 (sl)	2017-05-31	Novi sestavek cepiva proti influenci
IT1403147B1 (it)	2013-10-04	Procedimento per la produzione di pietre artificiali
IT1394292B1 (it)	2012-06-06	Procedimento per la sintesi di pregabalina
IT1402514B1 (it)	2013-09-13	Metodo di purificazione e metodo per produrre un vaccino
IT1394407B1 (it)	2012-06-15	Procedimento per la preparazione di fosinopril e suoi intermedi
IT1394219B1 (it)	2012-06-01	Metodo di preparazione di fesoterodina fumarato di elevata purezza.