SMT201400079B - Produzione di poliovirus ad alti titoli per la produzione di vaccino - Google Patents

Produzione di poliovirus ad alti titoli per la produzione di vaccino

Info

Publication number: SMT201400079B
Authority: SM; San Marino
Prior art keywords: production; poliovirus; high titers; vaccine; vaccine production
Prior art date: 2009-07-16

Application number

SM201400079T

Other languages

English (en)

Inventor

John Alfred Lewis

Original Assignee

Crucell Holland Bv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-07-16

Filing date

2014-06-24

Publication date

2014-09-08

2014-06-24 Application filed by Crucell Holland Bv filed Critical Crucell Holland Bv

2014-09-08 Publication of SMT201400079B publication Critical patent/SMT201400079B/it

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/02—Recovery or purification
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/125—Picornaviridae, e.g. calicivirus
- A61K39/13—Poliovirus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32611—Poliovirus
- C12N2770/32634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32611—Poliovirus
- C12N2770/32651—Methods of production or purification of viral material
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Virology (AREA)
Immunology (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Microbiology (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Genetics & Genomics (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Biomedical Technology (AREA)
Mycology (AREA)
Epidemiology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

SM201400079T 2009-07-16 2014-06-24 Produzione di poliovirus ad alti titoli per la produzione di vaccino SMT201400079B (it)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US27103809P	2009-07-16	2009-07-16
EP09165620		2009-07-16
PCT/EP2010/059796 WO2011006823A1 (en)	2009-07-16	2010-07-08	Production of polio virus at high titers for vaccine production
EP10729895.2A EP2454364B1 (en)	2009-07-16	2010-07-08	Production of polio virus at high titers for vaccine production

Publications (1)

Publication Number	Publication Date
SMT201400079B true SMT201400079B (it)	2014-09-08

Family

ID=41412431

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SM201400079T SMT201400079B (it)	2009-07-16	2014-06-24	Produzione di poliovirus ad alti titoli per la produzione di vaccino

Country Status (32)

Country	Link
US (4)	US8546123B2 (it)
EP (1)	EP2454364B1 (it)
JP (1)	JP5845178B2 (it)
KR (1)	KR101548790B1 (it)
CN (1)	CN102482647B (it)
AP (1)	AP3140A (it)
AR (1)	AR077314A1 (it)
AU (1)	AU2010272685B2 (it)
BR (1)	BR112012000942B8 (it)
CA (1)	CA2763091C (it)
CO (1)	CO6491042A2 (it)
CU (1)	CU20120006A7 (it)
DK (1)	DK2454364T3 (it)
EA (1)	EA020563B1 (it)
ES (1)	ES2484093T3 (it)
HR (1)	HRP20140597T1 (it)
IL (1)	IL217465A (it)
MA (1)	MA33429B1 (it)
MX (1)	MX2011012648A (it)
MY (1)	MY183385A (it)
NZ (1)	NZ596880A (it)
PE (1)	PE20120571A1 (it)
PL (1)	PL2454364T3 (it)
PT (1)	PT2454364E (it)
RS (1)	RS53377B (it)
SG (1)	SG177655A1 (it)
SI (1)	SI2454364T1 (it)
SM (1)	SMT201400079B (it)
TN (1)	TN2011000628A1 (it)
TW (1)	TWI477606B (it)
WO (1)	WO2011006823A1 (it)
ZA (1)	ZA201108271B (it)

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US9474798B2 (en)	2007-06-18	2016-10-25	Wisconsin Alumni Research Foundation	Influenza M2 protein mutant viruses as live influenza attenuated vaccines
WO2010060719A1 (en)	2008-11-03	2010-06-03	Crucell Holland B.V.	Method for the production of adenoviral vectors
RS53377B (sr)	2009-07-16	2014-10-31	Crucell Holland B.V.	Proizvodnja polio virusa u visokim titrima za proizvodnju vakcine
EP2493912B1 (en)	2009-10-26	2020-07-29	Wisconsin Alumni Research Foundation	High titer recombinant influenza viruses with enhanced replication in vero cells
US10130697B2 (en)	2010-03-23	2018-11-20	Wisconsin Alumni Research Foundation (Warf)	Vaccines comprising mutant attenuated influenza viruses
WO2013032942A1 (en)	2011-08-26	2013-03-07	Yoshihiro Kawaoka	Influenza viruses with mutant pb2 gene segment as live attenuated vaccines
CA2899928A1 (en) *	2013-02-05	2014-08-14	University Of Georgia Research Foundation, Inc.	Cell lines for virus production and methods of use
EP2863943B1 (en)	2013-03-08	2016-07-13	Crucell Holland B.V.	Acellular pertussis vaccine
CN105121634B (zh)	2013-03-13	2019-07-26	易木农麦克斯有限公司	具有提高的病毒生产能力的细胞系及其生产方法
KR20140112255A (ko)	2013-03-13	2014-09-23	고려대학교 산학협력단	바이러스 생산능이 증가된 세포주 및 그 제조방법
GB201305361D0 (en)	2013-03-25	2013-05-08	Univ Edinburgh	Enhanced expression
RS57864B1 (sr)	2013-06-17	2018-12-31	De Staat Der Nederlanden Vert Door De Minister Van Vws Ministerie Van Volksgezondheid Welzijn En Spo	Postupci za sprečavanje agregacije virusnih komponenti
US9950057B2 (en)	2013-07-15	2018-04-24	Wisconsin Alumni Research Foundation (Warf)	High titer recombinant influenza viruses with enhanced replication in MDCK or vero cells or eggs
US20160053281A1 (en) *	2013-08-15	2016-02-25	The University Court Of The University Of Edinburgh	Enhanced Expression Of RNA Vectors
JP6783143B2 (ja)	2014-03-25	2020-11-11	テルモビーシーティー、インコーポレーテッド	培地の受動的補充
WO2015193324A1 (en)	2014-06-17	2015-12-23	Crucell Holland B.V.	Cold-adapted-viral-attenuation (cava) and novel attenuated poliovirus strains
EP3159404B1 (en)	2014-06-18	2019-07-17	ImmunoMax Co., Ltd.	Method for promoting virus infection and increasing virus production, by using cell line having lost bst2 gene functions
WO2015196150A2 (en)	2014-06-20	2015-12-23	Wisconsin Alumni Research Foundation (Warf)	Mutations that confer genetic stability to additional genes in influenza viruses
US10294460B2 (en)	2014-07-24	2019-05-21	Janssen Vaccines & Prevention B.V.	Process for the purification of poliovirus from cell cultures
US10633422B2 (en)	2015-06-01	2020-04-28	Wisconsin Alumni Research Foundation (Warf)	Influenza virus replication by inhibiting microRNA lec7C binding to influenza viral cRNA and mRNA
WO2017004592A1 (en)	2015-07-02	2017-01-05	Terumo Bct, Inc.	Cell growth with mechanical stimuli
US9890363B2 (en)	2015-07-06	2018-02-13	Wisconsin Alumni Research Foundation (Warf)	Influenza virus replication for vaccine development
CA3014435C (en)	2016-02-19	2023-04-18	Wisconsin Alumni Research Foundation (Warf)	Improved influenza b virus replication for vaccine development
US11965175B2 (en)	2016-05-25	2024-04-23	Terumo Bct, Inc.	Cell expansion
US11685883B2 (en)	2016-06-07	2023-06-27	Terumo Bct, Inc.	Methods and systems for coating a cell growth surface
US11104874B2 (en)	2016-06-07	2021-08-31	Terumo Bct, Inc.	Coating a bioreactor
US10372100B2 (en) *	2016-08-29	2019-08-06	Ge Healthcare Bio-Sciences Corp.	Manufacturing system for biopharmaceutical products
JP7393945B2 (ja)	2017-03-31	2023-12-07	テルモビーシーティー、インコーポレーテッド	細胞増殖
CN107723279B (zh) *	2017-10-18	2020-11-10	成都远睿生物技术有限公司	一种缺陷型腺病毒AdC68-GP的培养方法
US11197926B2 (en)	2017-10-25	2021-12-14	Wisconsin Alumni Research Foundation (Warf)	Recombinant influenza viruses with stabilized HA for replication in eggs
SG11202007503WA (en) *	2018-02-07	2020-09-29	Bharat Biotech Int Ltd	A process for enterovirus purification and inactivation and vaccine compositions obtained thereof
JP7783047B2 (ja)	2018-08-07	2025-12-09	ウィスコンシンアルムニリサーチファンデイション	組換えの生物学的に封じ込められたフィロウイルスワクチン
WO2020041311A1 (en)	2018-08-20	2020-02-27	Wisconsin Alumni Research Foundation	Vectors for eliciting immune responses to non-dominant epitopes in the hemagglutinin (ha) protein
EP3914295A2 (en)	2019-01-23	2021-12-01	Yoshihiro Kawaoka	Mutations that confer genetic stability to additional genes in influenza viruses
US11851648B2 (en)	2019-02-08	2023-12-26	Wisconsin Alumni Research Foundation (Warf)	Humanized cell line
WO2020223699A1 (en)	2019-05-01	2020-11-05	Wisconsin Alumni Research Foundation (Warf)	Improved influenza virus replication for vaccine development
US20220175908A1 (en)	2019-05-16	2022-06-09	Janssen Vaccines & Prevention B.V.	Methods for Inducing a Safe Immune Response Against Polio Virus
JP7627911B2 (ja)	2019-08-27	2025-02-07	ウィスコンシンアルムニリサーチファンデイション	卵内複製のための安定化されたｈａを持つ組換えインフルエンザウイルス
US11739303B2 (en)	2020-01-24	2023-08-29	Wisconsin Alumni Research Foundation (Warf)	Recombinant influenza viruses with stabilized NA
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ES2456015T3 (es)	2004-03-05	2014-04-21	Dsm Ip Assets B.V.	Procedimiento para cultivar células mediante perfusión continua y flujo tangencial alternante
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BRPI0518146A (pt) *	2004-10-14	2008-10-28	Crucell Holland Bv	kit de partes, uso de um adenovìrus recombinante defectivo na replicação, e, método de vacinação de um mamìfero para a infecção por malária
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EP2081589B1 (en) *	2006-11-16	2010-10-06	Crucell Holland B.V.	Complementation of factor xi deficiency by factor v mutants
RS53377B (sr)	2009-07-16	2014-10-31	Crucell Holland B.V.	Proizvodnja polio virusa u visokim titrima za proizvodnju vakcine
KR20120070015A (ko)	2010-12-21	2012-06-29	(주)창조바이오텍	알파-피넨을 유효성분으로 포함하는 스쿠티카충 구제용 조성물

2010
- 2010-07-08 RS RS20140325A patent/RS53377B/sr unknown
- 2010-07-08 PL PL10729895T patent/PL2454364T3/pl unknown
- 2010-07-08 DK DK10729895.2T patent/DK2454364T3/da active
- 2010-07-08 AP AP2012006075A patent/AP3140A/xx active
- 2010-07-08 ES ES10729895.2T patent/ES2484093T3/es active Active
- 2010-07-08 JP JP2012519981A patent/JP5845178B2/ja not_active Expired - Fee Related
- 2010-07-08 CN CN201080026814.2A patent/CN102482647B/zh not_active Expired - Fee Related
- 2010-07-08 NZ NZ596880A patent/NZ596880A/xx not_active IP Right Cessation
- 2010-07-08 EA EA201270173A patent/EA020563B1/ru not_active IP Right Cessation
- 2010-07-08 BR BR112012000942A patent/BR112012000942B8/pt not_active IP Right Cessation
- 2010-07-08 AU AU2010272685A patent/AU2010272685B2/en not_active Ceased
- 2010-07-08 CA CA2763091A patent/CA2763091C/en active Active
- 2010-07-08 MA MA34534A patent/MA33429B1/fr unknown
- 2010-07-08 HR HRP20140597AT patent/HRP20140597T1/hr unknown
- 2010-07-08 WO PCT/EP2010/059796 patent/WO2011006823A1/en not_active Ceased
- 2010-07-08 MY MYPI2012000173A patent/MY183385A/en unknown
- 2010-07-08 SG SG2012002705A patent/SG177655A1/en unknown
- 2010-07-08 KR KR1020127001501A patent/KR101548790B1/ko not_active Expired - Fee Related
- 2010-07-08 EP EP10729895.2A patent/EP2454364B1/en active Active
- 2010-07-08 SI SI201030661T patent/SI2454364T1/sl unknown
- 2010-07-08 PT PT107298952T patent/PT2454364E/pt unknown
- 2010-07-08 MX MX2011012648A patent/MX2011012648A/es active IP Right Grant
- 2010-07-08 PE PE2012000051A patent/PE20120571A1/es active IP Right Grant
- 2010-07-14 AR ARP100102556A patent/AR077314A1/es active IP Right Grant
- 2010-07-15 TW TW099123327A patent/TWI477606B/zh not_active IP Right Cessation
- 2010-07-16 US US12/804,242 patent/US8546123B2/en not_active Expired - Fee Related
2011
- 2011-11-10 ZA ZA2011/08271A patent/ZA201108271B/en unknown
- 2011-12-07 TN TNP2011000628A patent/TN2011000628A1/en unknown
2012
- 2012-01-10 IL IL217465A patent/IL217465A/en active IP Right Grant
- 2012-01-13 CU CU2012000006A patent/CU20120006A7/es unknown
- 2012-01-16 CO CO12005515A patent/CO6491042A2/es unknown
- 2012-10-25 US US13/660,412 patent/US20130052224A1/en not_active Abandoned
2013
- 2013-03-15 US US13/843,052 patent/US20130273106A1/en not_active Abandoned
2014
- 2014-05-12 US US14/275,392 patent/US9022240B2/en active Active
- 2014-06-24 SM SM201400079T patent/SMT201400079B/it unknown

Also Published As

Publication number	Publication date
BR112012000942B1 (pt)	2020-10-27
CN102482647B (zh)	2015-12-16
EA201270173A1 (ru)	2012-06-29
TWI477606B (zh)	2015-03-21
WO2011006823A1 (en)	2011-01-20
HRP20140597T1 (hr)	2014-09-12
PT2454364E (pt)	2014-07-04
ES2484093T3 (es)	2014-08-11
US20140242670A1 (en)	2014-08-28
AU2010272685A1 (en)	2011-12-08
US20110027317A1 (en)	2011-02-03
AR077314A1 (es)	2011-08-17
CU20120006A7 (es)	2012-10-15
MX2011012648A (es)	2012-01-12
KR101548790B1 (ko)	2015-08-31
NZ596880A (en)	2013-10-25
US9022240B2 (en)	2015-05-05
EA020563B1 (ru)	2014-12-30
JP5845178B2 (ja)	2016-01-20
BR112012000942B8 (pt)	2021-05-25
RS53377B (sr)	2014-10-31
US20130273106A1 (en)	2013-10-17
PL2454364T3 (pl)	2014-09-30
DK2454364T3 (da)	2014-07-21
TW201118173A (en)	2011-06-01
IL217465A0 (en)	2012-02-29
CN102482647A (zh)	2012-05-30
US20130052224A1 (en)	2013-02-28
MA33429B1 (fr)	2012-07-03
BR112012000942A2 (pt)	2016-03-15
TN2011000628A1 (en)	2013-05-24
IL217465A (en)	2016-05-31
KR20120033334A (ko)	2012-04-06
CA2763091A1 (en)	2011-01-20
ZA201108271B (en)	2012-07-25
EP2454364A1 (en)	2012-05-23
MY183385A (en)	2021-02-18
SG177655A1 (en)	2012-02-28
SI2454364T1 (sl)	2014-08-29
AP3140A (en)	2015-02-28
AU2010272685B2 (en)	2015-02-26
CO6491042A2 (es)	2012-07-31
JP2012532616A (ja)	2012-12-20
PE20120571A1 (es)	2012-06-06
US8546123B2 (en)	2013-10-01
HK1164922A1 (en)	2012-09-28
AP2012006075A0 (en)	2012-02-29
CA2763091C (en)	2019-07-23
EP2454364B1 (en)	2014-04-23

Publication	Publication Date	Title
SMT201400079B (it)	2014-09-08	Produzione di poliovirus ad alti titoli per la produzione di vaccino
EP2429585A4 (en)	2013-03-06	VACCINE IMMUNOTHERAPY
SMT201600254B (it)	2016-08-31	Procedimento per la preparazione di idromagnesite
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