SK91395A3 - Lysine salt of 6-chloro-5-fluoro-3-(2-tenoyl)-2-oxindole-1- -carboxamide and pharmaceutical composition on their base - Google Patents

Lysine salt of 6-chloro-5-fluoro-3-(2-tenoyl)-2-oxindole-1- -carboxamide and pharmaceutical composition on their base Download PDF

Info

Publication number: SK91395A3
Authority: SK; Slovakia
Prior art keywords: oxindole; chloro; carboxamide; fluoro; tenoyl
Prior art date: 1993-01-22

Application number

SK913-95A

Other languages

English (en)

Slovak (sk)

Inventor

Kelvin Cooper

Thomas C Crawford

Bruce H Littman

Christopher J Pazoles

Sally G Ruggeri

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-01-22

Filing date

1994-01-06

Publication date

1996-12-04

1993-01-22 Priority claimed from US08/007,217 external-priority patent/US5298522A/en

1994-01-06 Application filed by Pfizer filed Critical Pfizer

1996-12-04 Publication of SK91395A3 publication Critical patent/SK91395A3/sk

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pain & Pain Management (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Rheumatology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Epidemiology (AREA)
Indole Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

SK913-95A 1993-01-22 1994-01-06 Lysine salt of 6-chloro-5-fluoro-3-(2-tenoyl)-2-oxindole-1- -carboxamide and pharmaceutical composition on their base SK91395A3 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US08/007,217 US5298522A (en)	1993-01-22	1993-01-22	6-chloro-5-fluoro-3-(2-thenoyl)-2-oxindole-1-carboxamide as an analgesic and anti-inflammatory agent while maintaining a normal urine protein/creatinine ratio
US13827793A	1993-10-18	1993-10-18
PCT/US1994/000096 WO1994016694A1 (fr)	1993-01-22	1994-01-06	Sel de lysine de 6-chloro-5-fluoro-3-(2-thenoyl)-2-oxindole-1-carboxamide

Publications (1)

Publication Number	Publication Date
SK91395A3 true SK91395A3 (en)	1996-12-04

Family

ID=26676677

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK913-95A SK91395A3 (en)	1993-01-22	1994-01-06	Lysine salt of 6-chloro-5-fluoro-3-(2-tenoyl)-2-oxindole-1- -carboxamide and pharmaceutical composition on their base

Country Status (27)

Country	Link
EP (1)	EP0680321B1 (fr)
JP (1)	JP2711939B2 (fr)
CN (1)	CN1116822A (fr)
AP (1)	AP468A (fr)
AT (1)	ATE171373T1 (fr)
AU (1)	AU671533B2 (fr)
BG (1)	BG61966B1 (fr)
BR (1)	BR9405661A (fr)
CA (1)	CA2153050C (fr)
CZ (1)	CZ182895A3 (fr)
DE (1)	DE69413518T2 (fr)
DK (1)	DK0680321T3 (fr)
DZ (1)	DZ1748A1 (fr)
ES (1)	ES2122236T3 (fr)
FI (1)	FI940309A7 (fr)
HU (1)	HUT69687A (fr)
IL (1)	IL108326A0 (fr)
LV (1)	LV10920B (fr)
MA (1)	MA23095A1 (fr)
NO (1)	NO952904D0 (fr)
NZ (1)	NZ261449A (fr)
OA (1)	OA10173A (fr)
PL (1)	PL309957A1 (fr)
SK (1)	SK91395A3 (fr)
UY (1)	UY23723A1 (fr)
WO (1)	WO1994016694A1 (fr)
YU (1)	YU48719B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1997022605A1 (fr) *	1995-12-19	1997-06-26	Pfizer Inc.	Sels stables et a action prolongee de derives d'indole pour le traitement de maladies articulaires
EP0826685A1 (fr) *	1996-08-21	1998-03-04	Pfizer Inc.	Sels de carboxamides stables à effet prolongé destinés au traitement des maladies articulaires
DE10106852A1 (de) *	2001-02-14	2002-09-05	T Luger	Entzündungshemmende Verbindungen

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4556672A (en) *	1984-03-19	1985-12-03	Pfizer Inc.	3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents
US4853409A (en) *	1988-04-13	1989-08-01	Pfizer Inc.	3-substituted-2-oxindole-1-carboxamides for suppressing T-cell function
DE4111305C2 (de) *	1991-04-08	1994-12-01	Mack Chem Pharm	Pharmazeutische Zubereitung zur rektalen Applikation, die ein 2-Oxindol-l-carboxamid-derivat enthält
DE4111306C2 (de) *	1991-04-08	1994-06-01	Mack Chem Pharm	Pharmazeutische Zubereitungen, die ein 2-Oxindol-l-carboxamid-derivat enthalten und zur Injektion bestimmt sind
US5298522A (en) *	1993-01-22	1994-03-29	Pfizer Inc.	6-chloro-5-fluoro-3-(2-thenoyl)-2-oxindole-1-carboxamide as an analgesic and anti-inflammatory agent while maintaining a normal urine protein/creatinine ratio

1994
- 1994-01-06 CN CN94190974A patent/CN1116822A/zh active Pending
- 1994-01-06 SK SK913-95A patent/SK91395A3/sk unknown
- 1994-01-06 DK DK94906511T patent/DK0680321T3/da active
- 1994-01-06 WO PCT/US1994/000096 patent/WO1994016694A1/fr not_active Ceased
- 1994-01-06 PL PL94309957A patent/PL309957A1/xx unknown
- 1994-01-06 CA CA002153050A patent/CA2153050C/fr not_active Expired - Fee Related
- 1994-01-06 CZ CZ951828A patent/CZ182895A3/cs unknown
- 1994-01-06 EP EP94906511A patent/EP0680321B1/fr not_active Expired - Lifetime
- 1994-01-06 BR BR9405661A patent/BR9405661A/pt not_active Application Discontinuation
- 1994-01-06 DE DE69413518T patent/DE69413518T2/de not_active Expired - Fee Related
- 1994-01-06 AU AU60198/94A patent/AU671533B2/en not_active Ceased
- 1994-01-06 NZ NZ261449A patent/NZ261449A/en unknown
- 1994-01-06 ES ES94906511T patent/ES2122236T3/es not_active Expired - Lifetime
- 1994-01-06 AT AT94906511T patent/ATE171373T1/de not_active IP Right Cessation
- 1994-01-06 JP JP6517040A patent/JP2711939B2/ja not_active Expired - Lifetime
- 1994-01-13 AP APAP/P/1994/000609A patent/AP468A/en active
- 1994-01-13 IL IL10832694A patent/IL108326A0/xx unknown
- 1994-01-19 DZ DZ940002A patent/DZ1748A1/fr active
- 1994-01-20 UY UY23723A patent/UY23723A1/es not_active IP Right Cessation
- 1994-01-21 HU HU9400176A patent/HUT69687A/hu unknown
- 1994-01-21 MA MA23401A patent/MA23095A1/fr unknown
- 1994-01-21 FI FI940309A patent/FI940309A7/fi unknown
- 1994-01-21 YU YU2394A patent/YU48719B/sh unknown
1995
- 1995-07-05 BG BG99767A patent/BG61966B1/bg unknown
- 1995-07-21 NO NO952904A patent/NO952904D0/no unknown
- 1995-07-21 OA OA60690A patent/OA10173A/en unknown
- 1995-07-21 LV LVP-95-220A patent/LV10920B/en unknown

Also Published As

Publication number	Publication date
ES2122236T3 (es)	1998-12-16
EP0680321A1 (fr)	1995-11-08
AP468A (en)	1996-03-05
CA2153050A1 (fr)	1994-08-04
CN1116822A (zh)	1996-02-14
CZ182895A3 (en)	1996-01-17
DE69413518D1 (en)	1998-10-29
BG99767A (bg)	1996-02-28
FI940309L (fi)	1994-07-23
PL309957A1 (en)	1995-11-13
JPH08501109A (ja)	1996-02-06
DK0680321T3 (da)	1999-06-14
MA23095A1 (fr)	1994-10-01
AU671533B2 (en)	1996-08-29
BG61966B1 (bg)	1998-11-30
IL108326A0 (en)	1994-04-12
FI940309A0 (fi)	1994-01-21
YU48719B (sh)	1999-07-28
OA10173A (en)	1996-12-18
LV10920A (lv)	1995-12-20
ATE171373T1 (de)	1998-10-15
EP0680321B1 (fr)	1998-09-23
BR9405661A (pt)	1995-11-21
AP9400609A0 (en)	1994-01-31
WO1994016694A1 (fr)	1994-08-04
UY23723A1 (es)	1994-06-28
HU9400176D0 (en)	1994-05-30
JP2711939B2 (ja)	1998-02-10
HUT69687A (en)	1995-09-28
AU6019894A (en)	1994-08-15
NZ261449A (en)	1996-08-27
FI940309A7 (fi)	1994-07-23
NO952904L (no)	1995-07-21
CA2153050C (fr)	1998-12-29
DZ1748A1 (fr)	2002-02-17
DE69413518T2 (de)	1999-02-11
LV10920B (en)	1996-04-20
NO952904D0 (no)	1995-07-21
YU2394A (sh)	1996-10-18

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