[go: up one dir, main page]

SK46797A3 - New peptides with immunomodulatory effects, preparation method thereof, pharmaceutical compositions containing them and their use - Google Patents

New peptides with immunomodulatory effects, preparation method thereof, pharmaceutical compositions containing them and their use Download PDF

Info

Publication number
SK46797A3
SK46797A3 SK467-97A SK46797A SK46797A3 SK 46797 A3 SK46797 A3 SK 46797A3 SK 46797 A SK46797 A SK 46797A SK 46797 A3 SK46797 A3 SK 46797A3
Authority
SK
Slovakia
Prior art keywords
leu
pro
cys
ile
gly
Prior art date
Application number
SK467-97A
Other languages
English (en)
Slovak (sk)
Inventor
Hakan Bergstrand
Tomas Eriksson
Kostas Karabelas
Magnus Lindvall
Bengt Sarnstrand
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of SK46797A3 publication Critical patent/SK46797A3/sk

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1005Tetrapeptides with the first amino acid being neutral and aliphatic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1005Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/101Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1024Tetrapeptides with the first amino acid being heterocyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
SK467-97A 1994-10-14 1995-10-06 New peptides with immunomodulatory effects, preparation method thereof, pharmaceutical compositions containing them and their use SK46797A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9403526A SE9403526D0 (sv) 1994-10-14 1994-10-14 New Peptides
PCT/SE1995/001151 WO1996011943A1 (en) 1994-10-14 1995-10-06 New peptides with immunomodulatory effects

Publications (1)

Publication Number Publication Date
SK46797A3 true SK46797A3 (en) 1997-09-10

Family

ID=20395628

Family Applications (1)

Application Number Title Priority Date Filing Date
SK467-97A SK46797A3 (en) 1994-10-14 1995-10-06 New peptides with immunomodulatory effects, preparation method thereof, pharmaceutical compositions containing them and their use

Country Status (20)

Country Link
US (2) US6103697A (pt)
EP (1) EP0783519A1 (pt)
JP (1) JPH10507448A (pt)
AU (1) AU705364B2 (pt)
BR (1) BR9509345A (pt)
CA (1) CA2201479A1 (pt)
CZ (1) CZ111997A3 (pt)
EE (1) EE9700087A (pt)
FI (1) FI971499L (pt)
HU (1) HUT77118A (pt)
IL (1) IL115509A0 (pt)
IS (1) IS4459A (pt)
MX (1) MX9702666A (pt)
NO (1) NO971625L (pt)
PL (1) PL319631A1 (pt)
SE (1) SE9403526D0 (pt)
SK (1) SK46797A3 (pt)
TR (1) TR199501255A2 (pt)
WO (1) WO1996011943A1 (pt)
ZA (1) ZA958140B (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9403526D0 (sv) 1994-10-14 1994-10-14 Astra Ab New Peptides
SE9501067D0 (sv) 1995-03-24 1995-03-24 Astra Ab New peptides
CA2250707A1 (en) * 1996-04-12 1997-10-23 Astra Aktiebolag Cysteine-containing or methionine-containing peptides with immunomodulatory effects
EP0914143A1 (en) * 1996-07-08 1999-05-12 Rhone-Poulenc Rorer Limited Medicinal cyclosporin-a aerosol solution formulation
SE9603465D0 (sv) * 1996-09-23 1996-09-23 Astra Ab New compounds
SE9603468D0 (sv) * 1996-09-23 1996-09-23 Astra Ab New compounds
SE9603467D0 (sv) * 1996-09-23 1996-09-23 Astra Ab New compounds
SE9603461D0 (sv) * 1996-09-23 1996-09-23 Astra Ab New compounds
SE9603466D0 (sv) * 1996-09-23 1996-09-23 Astra Ab New compounds
SE9603463D0 (sv) * 1996-09-23 1996-09-23 Astra Ab New compounds
SE9603462D0 (sv) * 1996-09-23 1996-09-23 Astra Ab New compounds
US20010049381A1 (en) 1997-06-04 2001-12-06 Gpl Nil Holdings, Inc., Pyrrolidine derivative hair growth compositions and uses
WO1999019347A1 (en) * 1997-10-10 1999-04-22 Astrazeneca Ab Synthetic genes with immunomodulatory effects
JP2002516839A (ja) * 1998-06-03 2002-06-11 ジーピーアイ エヌアイエル ホールディングス, インコーポレイテッド ピペコリン酸誘導体毛髪成長組成物およびその使用
RU2144374C1 (ru) * 1998-11-23 2000-01-20 Закрытое акционерное общество "ВАМ" Способ получения композита окисленного глутатиона с cis-диаминодихлорплатиной и фармацевтических композиций на его основе, регулирующих метаболизм, пролиферацию, дифференцировку и механизмы апоптоза нормальных и трансформированных клеток
JP4711520B2 (ja) * 2000-03-21 2011-06-29 日本ケミカルリサーチ株式会社 生理活性ペプチド含有粉末
US7265208B2 (en) * 2001-05-01 2007-09-04 The Regents Of The University Of California Fusion molecules and treatment of IgE-mediated allergic diseases
US8080560B2 (en) * 2004-12-17 2011-12-20 3M Innovative Properties Company Immune response modifier formulations containing oleic acid and methods
ES2388684T3 (es) 2005-04-25 2012-10-17 Cadila Pharmaceuticals Limited Adyuvantes de vacunas
KR101363455B1 (ko) * 2011-09-09 2014-02-21 (주)케어젠 매트릭스 메탈로프로테아제 활성 억제 펩타이드 및 이의 용도

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4585755A (en) * 1985-04-29 1986-04-29 Merck & Co., Inc. Cyclic and bridged cyclic somatostatin analogs useful as local anti-inflammatory agents
US4822606A (en) * 1986-04-07 1989-04-18 Duke University Immunosuppressive synthetic peptides and analogs thereof based on retroviral envelope sequences
AU1366088A (en) 1987-01-28 1988-08-24 Ortho Pharmaceutical Corporation Immunosuppressive peptides and methods of use
FR2622700B1 (fr) 1987-10-30 1993-08-13 Aderegem Proteine et ses fragments representant l'expression specifique du gene ps2 des cancers du sein, anticorps obtenus a partir de ladite proteine et/ou de ses fragments, leurs applications a la detection et au diagnostic de cancers du sein
EP0341603A3 (en) * 1988-05-09 1990-07-04 Abbott Laboratories Atrial peptide derivatives
US5223485A (en) * 1989-01-31 1993-06-29 Abbott Laboratories Anaphylatoxin-receptor ligands
JP2596466B2 (ja) 1990-03-03 1997-04-02 アサヒビール株式会社 ダニの主要アレルゲンの還伝情報を有するdnaおよび該アレルゲンの製造方法
JP3592709B2 (ja) 1990-09-11 2004-11-24 インスティテュート・フォー・チャイルド・ヘルス・リサーチ ダーマトファゴイデス(家塵ダニ)のアレルゲンのクローニングおよびシークエンシング
AU2296792A (en) * 1991-06-28 1993-01-25 Corvas International, Inc. Novel inhibitors of platelet aggregation
JP2657861B2 (ja) 1991-09-17 1997-09-30 アサヒビール株式会社 ダニ主要アレルゲンの製造方法
KR100260342B1 (ko) 1991-10-16 2000-07-01 스타세이 엘. 첸링 더마토파고이드로 부터 유래된 알레르겐의 t세포 에피토프
JP3149033B2 (ja) 1991-10-30 2001-03-26 アサヒビール株式会社 ダニ主要アレルゲンDer f II中のペプチド
JP3908271B2 (ja) 1993-03-05 2007-04-25 エピミューン,インコーポレイティド Hla−a2.1結合ペプチドおよびそれらの使用
IL106214A (en) * 1993-07-01 1998-12-06 Yeda Res & Dev Thf-gamma2 analogs and pharmaceutical compositions comprising them
JPH07215996A (ja) 1994-01-31 1995-08-15 Torii Yakuhin Kk ダニアレルゲンのb細胞エピトープ
DK0769054T3 (da) 1994-07-05 2000-11-13 Steeno Res Group As Immunmodulatorer
SE9403526D0 (sv) 1994-10-14 1994-10-14 Astra Ab New Peptides

Also Published As

Publication number Publication date
AU705364B2 (en) 1999-05-20
TR199501255A2 (tr) 1996-06-21
FI971499A7 (fi) 1997-06-10
FI971499A0 (fi) 1997-04-10
WO1996011943A1 (en) 1996-04-25
BR9509345A (pt) 1997-11-25
NO971625L (no) 1997-05-30
EE9700087A (et) 1997-10-15
CA2201479A1 (en) 1996-04-25
AU3713395A (en) 1996-05-06
JPH10507448A (ja) 1998-07-21
NO971625D0 (no) 1997-04-09
SE9403526D0 (sv) 1994-10-14
ZA958140B (en) 1997-06-27
CZ111997A3 (en) 1997-12-17
IL115509A0 (en) 1996-05-14
FI971499L (fi) 1997-06-10
EP0783519A1 (en) 1997-07-16
MX9702666A (es) 1997-06-28
HUT77118A (hu) 1998-03-02
PL319631A1 (en) 1997-08-18
US6228374B1 (en) 2001-05-08
IS4459A (is) 1997-04-08
US6103697A (en) 2000-08-15

Similar Documents

Publication Publication Date Title
SK46797A3 (en) New peptides with immunomodulatory effects, preparation method thereof, pharmaceutical compositions containing them and their use
JP3266311B2 (ja) 新規ポリペプチドおよびこれを用いる抗hiv剤
JP2514518B2 (ja) ヘプタペプチドおよびオクタペプチドのソマトスタチン類似アミド誘導体、それを含有する抗腫瘍剤
IE41510B1 (en) Peptides having lh-rh/fsh-rh activity and proces for their manufacture
CA2399187C (en) Kahalalide compounds
CA3073806A1 (en) Opioid agonist peptides and uses thereof
WO2004020462A1 (ja) Cxcr4拮抗薬およびその用途
JPH03504013A (ja) T細胞ヘルパー活性を有するペプチド
JP3178835B2 (ja) 新規ポリペプチドおよびこれを用いる抗hiv剤
HU203563B (en) Process for producing opioid-polypeptides and pharmaceutical compositions containing them
MXPA97002666A (en) New peptides with immunoregulated effects
JPWO1992004374A1 (ja) 新規ポリペプチドおよびこれを用いる抗hiv剤
AU641366B2 (en) Peptide compounds
JPH02500517A (ja) ペプチド化合物
CA2173939C (en) Oligopeptides derived from c-reactive protein fragments
US4684622A (en) Compositions and methods for producing vasodilation and antioxytocic activity
CN1781933B (zh) 胸腺素α1活性片段环肽类似物及其聚乙二醇化衍生物
US4599324A (en) V1-vasopressin antagonists
HU201964B (en) Process for producing peptides inhibiting maturation of t-lymphocytes and activity of macrophages, as well as pharmaceutical compositions comprising same
EP0269389A2 (en) Peptides
JP4781621B2 (ja) Cxcr4拮抗薬およびその用途
CA2098535A1 (en) Linear peptides
NZ251969A (en) Cyclic hexapeptide derivatives and analogs and compositions thereof
CN119684408A (zh) 一种高酶稳定性和抗炎活性的抗炎肽及其制备方法和应用
CA3017824C (en) Conjugates of tacrolimus, their compositions, and their uses