SK46797A3 - New peptides with immunomodulatory effects, preparation method thereof, pharmaceutical compositions containing them and their use - Google Patents
New peptides with immunomodulatory effects, preparation method thereof, pharmaceutical compositions containing them and their use Download PDFInfo
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- SK46797A3 SK46797A3 SK467-97A SK46797A SK46797A3 SK 46797 A3 SK46797 A3 SK 46797A3 SK 46797 A SK46797 A SK 46797A SK 46797 A3 SK46797 A3 SK 46797A3
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- 239000012188 paraffin wax Substances 0.000 description 1
- 239000003182 parenteral nutrition solution Substances 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
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- 239000000312 peanut oil Substances 0.000 description 1
- 229960001412 pentobarbital Drugs 0.000 description 1
- 238000010647 peptide synthesis reaction Methods 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 239000012071 phase Substances 0.000 description 1
- 239000008363 phosphate buffer Substances 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 108010031719 prolyl-serine Proteins 0.000 description 1
- 201000010174 renal carcinoma Diseases 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 238000004007 reversed phase HPLC Methods 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 235000019204 saccharin Nutrition 0.000 description 1
- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 description 1
- 229940081974 saccharin Drugs 0.000 description 1
- 239000000901 saccharin and its Na,K and Ca salt Substances 0.000 description 1
- 206010039667 schwannoma Diseases 0.000 description 1
- 230000007017 scission Effects 0.000 description 1
- 201000008407 sebaceous adenocarcinoma Diseases 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 238000012163 sequencing technique Methods 0.000 description 1
- 230000011664 signaling Effects 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 238000010532 solid phase synthesis reaction Methods 0.000 description 1
- 235000019337 sorbitan trioleate Nutrition 0.000 description 1
- 229960000391 sorbitan trioleate Drugs 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 206010041823 squamous cell carcinoma Diseases 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 201000010965 sweat gland carcinoma Diseases 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 238000001308 synthesis method Methods 0.000 description 1
- 201000000596 systemic lupus erythematosus Diseases 0.000 description 1
- 238000012353 t test Methods 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- HNKJADCVZUBCPG-UHFFFAOYSA-N thioanisole Chemical compound CSC1=CC=CC=C1 HNKJADCVZUBCPG-UHFFFAOYSA-N 0.000 description 1
- 239000000724 thymus hormone Substances 0.000 description 1
- 239000004408 titanium dioxide Substances 0.000 description 1
- 235000010215 titanium dioxide Nutrition 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 206010044412 transitional cell carcinoma Diseases 0.000 description 1
- 102000035160 transmembrane proteins Human genes 0.000 description 1
- 108091005703 transmembrane proteins Proteins 0.000 description 1
- 230000000472 traumatic effect Effects 0.000 description 1
- 208000010576 undifferentiated carcinoma Diseases 0.000 description 1
- 201000005112 urinary bladder cancer Diseases 0.000 description 1
- 210000001635 urinary tract Anatomy 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9403526A SE9403526D0 (sv) | 1994-10-14 | 1994-10-14 | New Peptides |
| PCT/SE1995/001151 WO1996011943A1 (en) | 1994-10-14 | 1995-10-06 | New peptides with immunomodulatory effects |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK46797A3 true SK46797A3 (en) | 1997-09-10 |
Family
ID=20395628
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK467-97A SK46797A3 (en) | 1994-10-14 | 1995-10-06 | New peptides with immunomodulatory effects, preparation method thereof, pharmaceutical compositions containing them and their use |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US6103697A (pt) |
| EP (1) | EP0783519A1 (pt) |
| JP (1) | JPH10507448A (pt) |
| AU (1) | AU705364B2 (pt) |
| BR (1) | BR9509345A (pt) |
| CA (1) | CA2201479A1 (pt) |
| CZ (1) | CZ111997A3 (pt) |
| EE (1) | EE9700087A (pt) |
| FI (1) | FI971499L (pt) |
| HU (1) | HUT77118A (pt) |
| IL (1) | IL115509A0 (pt) |
| IS (1) | IS4459A (pt) |
| MX (1) | MX9702666A (pt) |
| NO (1) | NO971625L (pt) |
| PL (1) | PL319631A1 (pt) |
| SE (1) | SE9403526D0 (pt) |
| SK (1) | SK46797A3 (pt) |
| TR (1) | TR199501255A2 (pt) |
| WO (1) | WO1996011943A1 (pt) |
| ZA (1) | ZA958140B (pt) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9403526D0 (sv) | 1994-10-14 | 1994-10-14 | Astra Ab | New Peptides |
| SE9501067D0 (sv) | 1995-03-24 | 1995-03-24 | Astra Ab | New peptides |
| CA2250707A1 (en) * | 1996-04-12 | 1997-10-23 | Astra Aktiebolag | Cysteine-containing or methionine-containing peptides with immunomodulatory effects |
| EP0914143A1 (en) * | 1996-07-08 | 1999-05-12 | Rhone-Poulenc Rorer Limited | Medicinal cyclosporin-a aerosol solution formulation |
| SE9603465D0 (sv) * | 1996-09-23 | 1996-09-23 | Astra Ab | New compounds |
| SE9603468D0 (sv) * | 1996-09-23 | 1996-09-23 | Astra Ab | New compounds |
| SE9603467D0 (sv) * | 1996-09-23 | 1996-09-23 | Astra Ab | New compounds |
| SE9603461D0 (sv) * | 1996-09-23 | 1996-09-23 | Astra Ab | New compounds |
| SE9603466D0 (sv) * | 1996-09-23 | 1996-09-23 | Astra Ab | New compounds |
| SE9603463D0 (sv) * | 1996-09-23 | 1996-09-23 | Astra Ab | New compounds |
| SE9603462D0 (sv) * | 1996-09-23 | 1996-09-23 | Astra Ab | New compounds |
| US20010049381A1 (en) | 1997-06-04 | 2001-12-06 | Gpl Nil Holdings, Inc., | Pyrrolidine derivative hair growth compositions and uses |
| WO1999019347A1 (en) * | 1997-10-10 | 1999-04-22 | Astrazeneca Ab | Synthetic genes with immunomodulatory effects |
| JP2002516839A (ja) * | 1998-06-03 | 2002-06-11 | ジーピーアイ エヌアイエル ホールディングス, インコーポレイテッド | ピペコリン酸誘導体毛髪成長組成物およびその使用 |
| RU2144374C1 (ru) * | 1998-11-23 | 2000-01-20 | Закрытое акционерное общество "ВАМ" | Способ получения композита окисленного глутатиона с cis-диаминодихлорплатиной и фармацевтических композиций на его основе, регулирующих метаболизм, пролиферацию, дифференцировку и механизмы апоптоза нормальных и трансформированных клеток |
| JP4711520B2 (ja) * | 2000-03-21 | 2011-06-29 | 日本ケミカルリサーチ株式会社 | 生理活性ペプチド含有粉末 |
| US7265208B2 (en) * | 2001-05-01 | 2007-09-04 | The Regents Of The University Of California | Fusion molecules and treatment of IgE-mediated allergic diseases |
| US8080560B2 (en) * | 2004-12-17 | 2011-12-20 | 3M Innovative Properties Company | Immune response modifier formulations containing oleic acid and methods |
| ES2388684T3 (es) | 2005-04-25 | 2012-10-17 | Cadila Pharmaceuticals Limited | Adyuvantes de vacunas |
| KR101363455B1 (ko) * | 2011-09-09 | 2014-02-21 | (주)케어젠 | 매트릭스 메탈로프로테아제 활성 억제 펩타이드 및 이의 용도 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4585755A (en) * | 1985-04-29 | 1986-04-29 | Merck & Co., Inc. | Cyclic and bridged cyclic somatostatin analogs useful as local anti-inflammatory agents |
| US4822606A (en) * | 1986-04-07 | 1989-04-18 | Duke University | Immunosuppressive synthetic peptides and analogs thereof based on retroviral envelope sequences |
| AU1366088A (en) | 1987-01-28 | 1988-08-24 | Ortho Pharmaceutical Corporation | Immunosuppressive peptides and methods of use |
| FR2622700B1 (fr) | 1987-10-30 | 1993-08-13 | Aderegem | Proteine et ses fragments representant l'expression specifique du gene ps2 des cancers du sein, anticorps obtenus a partir de ladite proteine et/ou de ses fragments, leurs applications a la detection et au diagnostic de cancers du sein |
| EP0341603A3 (en) * | 1988-05-09 | 1990-07-04 | Abbott Laboratories | Atrial peptide derivatives |
| US5223485A (en) * | 1989-01-31 | 1993-06-29 | Abbott Laboratories | Anaphylatoxin-receptor ligands |
| JP2596466B2 (ja) | 1990-03-03 | 1997-04-02 | アサヒビール株式会社 | ダニの主要アレルゲンの還伝情報を有するdnaおよび該アレルゲンの製造方法 |
| JP3592709B2 (ja) | 1990-09-11 | 2004-11-24 | インスティテュート・フォー・チャイルド・ヘルス・リサーチ | ダーマトファゴイデス(家塵ダニ)のアレルゲンのクローニングおよびシークエンシング |
| AU2296792A (en) * | 1991-06-28 | 1993-01-25 | Corvas International, Inc. | Novel inhibitors of platelet aggregation |
| JP2657861B2 (ja) | 1991-09-17 | 1997-09-30 | アサヒビール株式会社 | ダニ主要アレルゲンの製造方法 |
| KR100260342B1 (ko) | 1991-10-16 | 2000-07-01 | 스타세이 엘. 첸링 | 더마토파고이드로 부터 유래된 알레르겐의 t세포 에피토프 |
| JP3149033B2 (ja) | 1991-10-30 | 2001-03-26 | アサヒビール株式会社 | ダニ主要アレルゲンDer f II中のペプチド |
| JP3908271B2 (ja) | 1993-03-05 | 2007-04-25 | エピミューン,インコーポレイティド | Hla−a2.1結合ペプチドおよびそれらの使用 |
| IL106214A (en) * | 1993-07-01 | 1998-12-06 | Yeda Res & Dev | Thf-gamma2 analogs and pharmaceutical compositions comprising them |
| JPH07215996A (ja) | 1994-01-31 | 1995-08-15 | Torii Yakuhin Kk | ダニアレルゲンのb細胞エピトープ |
| DK0769054T3 (da) | 1994-07-05 | 2000-11-13 | Steeno Res Group As | Immunmodulatorer |
| SE9403526D0 (sv) | 1994-10-14 | 1994-10-14 | Astra Ab | New Peptides |
-
1994
- 1994-10-14 SE SE9403526A patent/SE9403526D0/xx unknown
-
1995
- 1995-09-27 ZA ZA958140A patent/ZA958140B/xx unknown
- 1995-10-03 IL IL11550995A patent/IL115509A0/xx unknown
- 1995-10-06 CA CA002201479A patent/CA2201479A1/en not_active Abandoned
- 1995-10-06 PL PL95319631A patent/PL319631A1/xx unknown
- 1995-10-06 EP EP95934921A patent/EP0783519A1/en not_active Withdrawn
- 1995-10-06 EE EE9700087A patent/EE9700087A/xx unknown
- 1995-10-06 SK SK467-97A patent/SK46797A3/sk unknown
- 1995-10-06 AU AU37133/95A patent/AU705364B2/en not_active Ceased
- 1995-10-06 HU HU9702044A patent/HUT77118A/hu unknown
- 1995-10-06 FI FI971499A patent/FI971499L/fi unknown
- 1995-10-06 JP JP8513146A patent/JPH10507448A/ja active Pending
- 1995-10-06 BR BR9509345A patent/BR9509345A/pt not_active Application Discontinuation
- 1995-10-06 WO PCT/SE1995/001151 patent/WO1996011943A1/en not_active Ceased
- 1995-10-06 CZ CZ971119A patent/CZ111997A3/cs unknown
- 1995-10-06 MX MX9702666A patent/MX9702666A/es unknown
- 1995-10-06 US US08/836,480 patent/US6103697A/en not_active Expired - Fee Related
- 1995-10-12 TR TR95/01255A patent/TR199501255A2/xx unknown
-
1997
- 1997-04-08 IS IS4459A patent/IS4459A/is unknown
- 1997-04-09 NO NO971625A patent/NO971625L/no unknown
-
2000
- 2000-05-01 US US09/562,897 patent/US6228374B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU705364B2 (en) | 1999-05-20 |
| TR199501255A2 (tr) | 1996-06-21 |
| FI971499A7 (fi) | 1997-06-10 |
| FI971499A0 (fi) | 1997-04-10 |
| WO1996011943A1 (en) | 1996-04-25 |
| BR9509345A (pt) | 1997-11-25 |
| NO971625L (no) | 1997-05-30 |
| EE9700087A (et) | 1997-10-15 |
| CA2201479A1 (en) | 1996-04-25 |
| AU3713395A (en) | 1996-05-06 |
| JPH10507448A (ja) | 1998-07-21 |
| NO971625D0 (no) | 1997-04-09 |
| SE9403526D0 (sv) | 1994-10-14 |
| ZA958140B (en) | 1997-06-27 |
| CZ111997A3 (en) | 1997-12-17 |
| IL115509A0 (en) | 1996-05-14 |
| FI971499L (fi) | 1997-06-10 |
| EP0783519A1 (en) | 1997-07-16 |
| MX9702666A (es) | 1997-06-28 |
| HUT77118A (hu) | 1998-03-02 |
| PL319631A1 (en) | 1997-08-18 |
| US6228374B1 (en) | 2001-05-08 |
| IS4459A (is) | 1997-04-08 |
| US6103697A (en) | 2000-08-15 |
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