SK284879B6 - Polypeptidy so schopnosťou tvorby väzbových štruktúr na antigén so špecificitou pre Rhesus D antigény, DNA kódujúce také polypeptidy, spôsob ich prípravy a použitie - Google Patents

Polypeptidy so schopnosťou tvorby väzbových štruktúr na antigén so špecificitou pre Rhesus D antigény, DNA kódujúce také polypeptidy, spôsob ich prípravy a použitie Download PDF

Info

Publication number: SK284879B6
Authority: SK; Slovakia
Prior art keywords: ser; gly; thr; leu; ala
Prior art date: 1996-06-24

Application number

SK1761-98A

Other languages

English (en)

Slovak (sk)

Other versions

SK176198A3 (en

Inventor

Sylvia Miescher

Monique Vogel

Beda Stadler

Andreas Morell

Martin Imboden

Hanspeter Amstutz

Original Assignee

Zlb Behring Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-06-24

Filing date

1997-06-20

Publication date

2006-01-05

1997-06-20 Application filed by Zlb Behring Ag filed Critical Zlb Behring Ag

1999-07-12 Publication of SK176198A3 publication Critical patent/SK176198A3/sk

2006-01-05 Publication of SK284879B6 publication Critical patent/SK284879B6/sk

Links

239000000427 antigen Substances 0.000 title claims abstract description 47
108091007433 antigens Proteins 0.000 title claims abstract description 47
102000036639 antigens Human genes 0.000 title claims abstract description 47
229920001184 polypeptide Polymers 0.000 title claims abstract description 16
102000004196 processed proteins & peptides Human genes 0.000 title claims abstract description 16
108090000765 processed proteins & peptides Proteins 0.000 title claims abstract description 16
238000002360 preparation method Methods 0.000 title abstract description 13
238000000034 method Methods 0.000 title description 25
230000008569 process Effects 0.000 title description 4
125000003275 alpha amino acid group Chemical group 0.000 claims 1
102000001706 Immunoglobulin Fab Fragments Human genes 0.000 abstract description 16
108010054477 Immunoglobulin Fab Fragments Proteins 0.000 abstract description 16
108091028043 Nucleic acid sequence Proteins 0.000 abstract description 5
239000000203 mixture Substances 0.000 abstract description 4
239000004480 active ingredient Substances 0.000 abstract 1
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210000003743 erythrocyte Anatomy 0.000 description 88
150000001413 amino acids Chemical group 0.000 description 67
239000002299 complementary DNA Substances 0.000 description 66
210000004027 cell Anatomy 0.000 description 59
108090000623 proteins and genes Proteins 0.000 description 52
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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/34—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood group antigens
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/80—Antibody or fragment thereof whose amino acid sequence is disclosed in whole or in part
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/81—Drug, bio-affecting and body treating compositions involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, immunotolerance, or anergy
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/868—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, or immunotolerance

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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Hematology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Biomedical Technology (AREA)
Microbiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biophysics (AREA)
Biotechnology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Urology & Nephrology (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Physics & Mathematics (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Food Science & Technology (AREA)
Pathology (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Cell Biology (AREA)
Mycology (AREA)
Epidemiology (AREA)
General Engineering & Computer Science (AREA)
Analytical Chemistry (AREA)
General Physics & Mathematics (AREA)
Diabetes (AREA)
General Chemical & Material Sciences (AREA)
Gastroenterology & Hepatology (AREA)
Plant Pathology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)

SK1761-98A 1996-06-24 1997-06-20 Polypeptidy so schopnosťou tvorby väzbových štruktúr na antigén so špecificitou pre Rhesus D antigény, DNA kódujúce také polypeptidy, spôsob ich prípravy a použitie SK284879B6 (sk)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP96810421		1996-06-24
PCT/EP1997/003253 WO1997049809A1 (en)	1996-06-24	1997-06-20	Polypeptides capable of forming antigen binding structures with specificity for the rhesus d antigens, the dna encoding them and the process for their preparation and use

Publications (2)

Publication Number	Publication Date
SK176198A3 SK176198A3 (en)	1999-07-12
SK284879B6 true SK284879B6 (sk)	2006-01-05

Family

ID=8225636

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK1761-98A SK284879B6 (sk)	1996-06-24	1997-06-20	Polypeptidy so schopnosťou tvorby väzbových štruktúr na antigén so špecificitou pre Rhesus D antigény, DNA kódujúce také polypeptidy, spôsob ich prípravy a použitie

Country Status (23)

Country	Link
US (3)	US7038020B1 (is)
EP (1)	EP0920509B1 (is)
JP (1)	JP3841360B2 (is)
KR (1)	KR100361449B1 (is)
AT (1)	ATE272116T1 (is)
AU (1)	AU722127B2 (is)
BG (1)	BG64534B1 (is)
BR (1)	BR9709958A (is)
CA (1)	CA2258494C (is)
CZ (1)	CZ296807B6 (is)
DE (1)	DE69730031T2 (is)
DK (1)	DK0920509T3 (is)
ES (1)	ES2224255T3 (is)
HU (1)	HUP9902605A3 (is)
IL (1)	IL127595A (is)
IS (1)	IS2220B (is)
NO (1)	NO327947B1 (is)
NZ (1)	NZ333329A (is)
PL (1)	PL186019B1 (is)
RU (1)	RU2204602C2 (is)
SK (1)	SK284879B6 (is)
TR (1)	TR199802692T2 (is)
WO (1)	WO1997049809A1 (is)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU1631000A (en) *	1998-11-19	2000-06-05	Incyte Pharmaceuticals, Inc.	Immunoglobulin superfamily proteins
EP1106625A1 (en) *	1999-11-17	2001-06-13	ZLB Bioplasma AG	Rhesus D specific peptide sequences
FR2807767B1 (fr)	2000-04-12	2005-01-14	Lab Francais Du Fractionnement	Anticorps monoclonaux anti-d
US20040029113A1 (en)	2000-04-17	2004-02-12	Ladner Robert C.	Novel methods of constructing libraries of genetic packages that collectively display the members of a diverse family of peptides, polypeptides or proteins
US8288322B2 (en)	2000-04-17	2012-10-16	Dyax Corp.	Methods of constructing libraries comprising displayed and/or expressed members of a diverse family of peptides, polypeptides or proteins and the novel libraries
AU2002226049A1 (en) *	2000-12-05	2002-06-18	Alexion Pharmaceuticals, Inc.	Engineered plasmids and their use for in situ production of genes
PT2316940E (pt)	2000-12-18	2013-10-16	Dyax Corp	Bibliotecas orientadas de pacotes genéticos
AU2016225923B2 (en) *	2001-04-17	2018-07-05	Takeda Pharmaceutical Company Limited	Novel Methods of Constructing Libraries Comprising Displayed and/or Expressed Members of a Diverse Family of Peptides, Polypeptides or Proteins and the Novel Libraries
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1997
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Also Published As

Publication number	Publication date
NO986088L (no)	1999-02-24
PL186019B1 (pl)	2003-09-30
DE69730031T2 (de)	2005-06-16
IL127595A0 (en)	1999-10-28
BG103016A (en)	1999-08-31
KR100361449B1 (ko)	2003-01-24
SK176198A3 (en)	1999-07-12
DE69730031D1 (de)	2004-09-02
ATE272116T1 (de)	2004-08-15
CA2258494A1 (en)	1997-12-31
KR20000022530A (ko)	2000-04-25
ES2224255T3 (es)	2005-03-01
US7429647B2 (en)	2008-09-30
PL330794A1 (en)	1999-06-07
HUP9902605A3 (en)	2001-11-28
US7399471B2 (en)	2008-07-15
BG64534B1 (bg)	2005-06-30
RU2204602C2 (ru)	2003-05-20
BR9709958A (pt)	1999-08-10
EP0920509B1 (en)	2004-07-28
WO1997049809A1 (en)	1997-12-31
IS2220B (is)	2007-03-15
JP3841360B2 (ja)	2006-11-01
CZ395998A3 (cs)	1999-05-12
NZ333329A (en)	2000-07-28
NO986088D0 (no)	1998-12-23
IS4922A (is)	1998-12-11
AU722127B2 (en)	2000-07-20
EP0920509A1 (en)	1999-06-09
CZ296807B6 (cs)	2006-06-14
US20060165694A1 (en)	2006-07-27
NO327947B1 (no)	2009-10-26
AU3342397A (en)	1998-01-14
IL127595A (en)	2005-09-25
US20050266013A1 (en)	2005-12-01
CA2258494C (en)	2008-05-27
HUP9902605A2 (hu)	1999-11-29
DK0920509T3 (da)	2004-12-06
JP2000515732A (ja)	2000-11-28
TR199802692T2 (xx)	1999-03-22
US7038020B1 (en)	2006-05-02

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