[go: up one dir, main page]

SK168597A3 - Use of 1,2,4-triazole derivatives for the manufacture of a medicament for the treatment of cancers - Google Patents

Use of 1,2,4-triazole derivatives for the manufacture of a medicament for the treatment of cancers Download PDF

Info

Publication number
SK168597A3
SK168597A3 SK1685-97A SK168597A SK168597A3 SK 168597 A3 SK168597 A3 SK 168597A3 SK 168597 A SK168597 A SK 168597A SK 168597 A3 SK168597 A3 SK 168597A3
Authority
SK
Slovakia
Prior art keywords
triazole
group
dioxolan
dichlorophenyl
ylmethyl
Prior art date
Application number
SK1685-97A
Other languages
English (en)
Slovak (sk)
Inventor
James B Camden
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of SK168597A3 publication Critical patent/SK168597A3/sk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SK1685-97A 1995-06-07 1996-05-22 Use of 1,2,4-triazole derivatives for the manufacture of a medicament for the treatment of cancers SK168597A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/473,819 US5770616A (en) 1995-06-07 1995-06-07 Pharmaceutical composition for inhibiting the growth of cancers
PCT/US1996/007444 WO1996040119A1 (en) 1995-06-07 1996-05-22 Use of 1,2,4-triazole derivatives for the manufacture of a medicament for the treatment of cancers

Publications (1)

Publication Number Publication Date
SK168597A3 true SK168597A3 (en) 1998-12-02

Family

ID=23881121

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1685-97A SK168597A3 (en) 1995-06-07 1996-05-22 Use of 1,2,4-triazole derivatives for the manufacture of a medicament for the treatment of cancers

Country Status (20)

Country Link
US (4) US5770616A (es)
EP (1) EP0831814A1 (es)
JP (1) JPH11508233A (es)
KR (1) KR19990022619A (es)
CN (1) CN1190344A (es)
AR (1) AR003138A1 (es)
AU (1) AU707077B2 (es)
BR (1) BR9608731A (es)
CA (1) CA2223967A1 (es)
CZ (1) CZ391797A3 (es)
HU (1) HUP9802677A3 (es)
IL (1) IL118425A (es)
NO (1) NO975662L (es)
NZ (1) NZ308391A (es)
PL (1) PL324107A1 (es)
RU (1) RU2177316C2 (es)
SK (1) SK168597A3 (es)
TR (2) TR199801323T2 (es)
WO (1) WO1996040119A1 (es)
ZA (1) ZA964374B (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6177460B1 (en) 1995-04-12 2001-01-23 The Procter & Gamble Company Method of treatment for cancer or viral infections
US6479526B1 (en) 1995-04-12 2002-11-12 The Procter & Gamble Company Pharmaceutical composition for inhibiting the growth of viruses and cancers
US6262093B1 (en) 1995-04-12 2001-07-17 The Proctor & Gamble Company Methods of treating cancer with benzimidazoles
US6200992B1 (en) * 1995-06-07 2001-03-13 The Procter & Gamble Company Pharmaceutical composition for inhibiting the growth of cancers
US5770616A (en) * 1995-06-07 1998-06-23 The Procter & Gamble Company Pharmaceutical composition for inhibiting the growth of cancers
US6265427B1 (en) 1995-06-07 2001-07-24 The Proctor & Gamble Company Pharmaceutical composition for the method of treating leukemia
US5908855A (en) * 1996-07-16 1999-06-01 The Procter & Gamble Company Compositions for treating viral infections
US6686391B2 (en) 1995-08-04 2004-02-03 University Of Arizona Foundation N-chlorophenylcarbamate and N-chlorophenylthiocarbamate compositions
US5900429A (en) 1997-01-28 1999-05-04 The Procter & Gamble Company Method for inhibiting the growth of cancers
US6506783B1 (en) 1997-05-16 2003-01-14 The Procter & Gamble Company Cancer treatments and pharmaceutical compositions therefor
US6245789B1 (en) 1998-05-19 2001-06-12 The Procter & Gamble Company HIV and viral treatment
US6423734B1 (en) * 1999-08-13 2002-07-23 The Procter & Gamble Company Method of preventing cancer
US6380232B1 (en) 2000-09-26 2002-04-30 The Procter & Gamble Company Benzimidazole urea derivatives, and pharmaceutical compositions and unit dosages thereof
US6407105B1 (en) 2000-09-26 2002-06-18 The Procter & Gamble Company Compounds and methods for use thereof in the treatment of cancer or viral infections
US6462062B1 (en) * 2000-09-26 2002-10-08 The Procter & Gamble Company Compounds and methods for use thereof in the treatment of cancer or viral infections
US6608096B1 (en) * 2000-09-26 2003-08-19 University Of Arizona Foundation Compounds and methods for use thereof in the treatment of cancer or viral infections
US6515074B2 (en) * 2001-01-22 2003-02-04 Delphi Technologies, Inc. Thermoplastic polymer alloy compositions and process for manufacture thereof
CN100334084C (zh) * 2005-04-26 2007-08-29 武汉大学 联三唑化合物及其制备方法和用途
WO2007005644A2 (en) * 2005-07-01 2007-01-11 Concert Pharmaceuticals Inc. Novel aryloxypropanamines
WO2007062119A1 (en) * 2005-11-23 2007-05-31 Auspex Pharmaceuticals, Inc. Substituted aryloxypropylamines with serotoninergic and/or norepinephrinergic activity

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4079062A (en) * 1974-11-18 1978-03-14 Janssen Pharmaceutica N.V. Triazole derivatives
US4160838A (en) * 1977-06-02 1979-07-10 Janssen Pharmaceutica N.V. Antimicrobial and plant-growth-regulating triazole derivatives
GB2078719B (en) * 1980-06-02 1984-04-26 Ici Ltd Heterocyclic compounds
EP0069442B1 (en) * 1981-06-06 1985-02-20 Pfizer Limited Antifungal agents, processes for their preparation, and pharmaceutical compositions containing them
US4490540A (en) * 1981-09-14 1984-12-25 Janssen Pharmaceutica N.V. (2-Aryl-4-phenylthioalkyl-1,3-dioxolan-2-ylmethyl)azole derivatives
DE3238903A1 (de) * 1982-10-21 1984-04-26 Bayer Ag, 5090 Leverkusen Antivirales mittel
DE3511411A1 (de) * 1985-03-29 1986-10-02 Basf Ag, 6700 Ludwigshafen Verwendung von azolylmethyloxiranen zur bekaempfung von viralen erkrankungen
DE3511409A1 (de) * 1985-03-29 1986-10-02 Basf Ag, 6700 Ludwigshafen Herstellung von arzneimitteln gegen viruserkrankungen
EP0196855A3 (en) * 1985-03-29 1989-04-12 Pfizer Inc. Tioconazole and related compounds for prevention of sexually transmitted diseases and control of herpetic infections
US5211736A (en) * 1988-05-09 1993-05-18 Uniroyal Chemical Company, Inc. Azole derivatives of spiroheterocycles
DE3837463A1 (de) * 1988-11-04 1990-05-10 Bayer Ag Substituierte bisazole, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
JPH02257929A (ja) * 1989-03-09 1990-10-18 Makutaa Kk 生体透過率測定器
US5114951A (en) * 1989-04-11 1992-05-19 Burroughs Wellcome Company Agents for combating multiple drug resistance
BE1004029A6 (nl) * 1990-11-22 1992-09-08 Mol Omer De Farmaceutische samenstelling en farmaceutische set voor het behandelen van kanker.
DE69230225T2 (de) 1991-09-02 2000-05-31 Yamanouchi Pharmaceutical Co., Ltd. Triazolylierte tertiäre aminverbindungen oder ihre salze
US5360612A (en) * 1992-10-13 1994-11-01 Pfizer Inc. Pharmaceutical compositions containing triazole derivatives for rectal administration
US5565478A (en) * 1994-03-14 1996-10-15 The United States Of America As Represented By The Department Of Health & Human Services Combination therapy using signal transduction inhibitors with paclitaxel and other taxane analogs
US5656615A (en) 1995-04-12 1997-08-12 The Procter & Gamble Company Pharmaceutical composition for inhibiting the growth of cancers and viruses in mammals
NZ305784A (en) 1995-04-12 2001-03-30 Procter & Gamble Benzimidazole containing medicaments for treating cancers, tumors and viral infections
US5665713A (en) 1995-04-12 1997-09-09 Procter & Gamble Company Pharmaceutical composition for inhibiting the growth of viruses and cancers
ZA962879B (en) 1995-04-12 1997-03-17 Procter & Gamble A pharmaceutical composition for inhibiting the growth of viruses and cancers
US5629341A (en) 1995-04-12 1997-05-13 The Procter & Gamble Company Pharmaceutical composition for inhibiting the growth of viruses and cancers
JPH11503460A (ja) 1995-04-12 1999-03-26 ザ プロクター アンド ギャンブル カンパニー ウィルスおよび癌の増殖を阻止するｎ−クロロフェニルカルバメートおよびｎ−クロロフェニルチオカルバメート含有医薬組成物
ZA962880B (en) 1995-04-12 1997-03-17 Procter & Gamble A pharmaceutical composition for inhibiting the growth of viruses and cancers
US6200992B1 (en) 1995-06-07 2001-03-13 The Procter & Gamble Company Pharmaceutical composition for inhibiting the growth of cancers
CZ391197A3 (cs) 1995-06-07 1998-05-13 The Procter & Gamble Company Použití benzimidazolů pro přípravu léčiva pro léčení leukémie
US5770616A (en) 1995-06-07 1998-06-23 The Procter & Gamble Company Pharmaceutical composition for inhibiting the growth of cancers
MX9707809A (es) 1995-06-07 1998-01-31 Procter & Gamble Una composicion farmaceutica que contiene bencimidazol para inhibir el crecimiento de canceres.
US5665751A (en) 1995-06-07 1997-09-09 The Procter & Gamble Company Pharmaceutical composition for inhibiting the growth of cancers
MX9800945A (es) 1995-08-03 1998-04-30 Procter & Gamble Uso de griseofulvina para inhibir el crecimiento de canceres.
JPH11510187A (ja) 1995-08-04 1999-09-07 ザ プロクター アンド ギャンブル カンパニー 癌の成長を阻害するためのフルコナゾールの使用
US5908855A (en) 1996-07-16 1999-06-01 The Procter & Gamble Company Compositions for treating viral infections
US5900429A (en) 1997-01-28 1999-05-04 The Procter & Gamble Company Method for inhibiting the growth of cancers
PE11499A1 (es) 1997-05-16 1999-03-01 Procter & Gamble Tratamiento del hiv y cancer
US6506783B1 (en) 1997-05-16 2003-01-14 The Procter & Gamble Company Cancer treatments and pharmaceutical compositions therefor
US6245789B1 (en) 1998-05-19 2001-06-12 The Procter & Gamble Company HIV and viral treatment

Also Published As

Publication number Publication date
IL118425A0 (en) 1996-09-12
TR199701534T1 (xx) 1998-02-21
US5872142A (en) 1999-02-16
HUP9802677A3 (en) 1999-11-29
ZA964374B (en) 1997-02-17
US5770616A (en) 1998-06-23
HUP9802677A2 (hu) 1999-08-30
JPH11508233A (ja) 1999-07-21
CN1190344A (zh) 1998-08-12
WO1996040119A1 (en) 1996-12-19
AU5801996A (en) 1996-12-30
CZ391797A3 (cs) 1998-05-13
US6228876B1 (en) 2001-05-08
AR003138A1 (es) 1998-07-08
IL118425A (en) 2001-05-20
EP0831814A1 (en) 1998-04-01
NO975662L (no) 1998-02-09
NO975662D0 (no) 1997-12-05
BR9608731A (pt) 1999-06-29
CA2223967A1 (en) 1996-12-19
US6025377A (en) 2000-02-15
KR19990022619A (ko) 1999-03-25
RU2177316C2 (ru) 2001-12-27
AU707077B2 (en) 1999-07-01
TR199801323T2 (xx) 1998-09-21
NZ308391A (en) 2000-05-26
PL324107A1 (en) 1998-05-11

Similar Documents

Publication Publication Date Title
SK168597A3 (en) Use of 1,2,4-triazole derivatives for the manufacture of a medicament for the treatment of cancers
US5880144A (en) Pharmaceutical composition for inhibiting the growth of viruses and cancers comprising thiabendazole
EP0821586B1 (en) A pharmaceutical composition containing benzimidazole for inhibiting the growth of cancers
US5665713A (en) Pharmaceutical composition for inhibiting the growth of viruses and cancers
SK168797A3 (en) Use of bis-1,2,4-triazoles for the manufacture of a medicament for the treatment of cancers
US5656615A (en) Pharmaceutical composition for inhibiting the growth of cancers and viruses in mammals
US5629341A (en) Pharmaceutical composition for inhibiting the growth of viruses and cancers
SK46999A3 (en) Pharmaceutical composition
US5929099A (en) Pharmaceutical composition for inhibiting the growth of cancers
NZ305785A (en) A pharmaceutical composition containing n-chlorophenylcarbamates and n-chlorophenylthiocarbamates for inhibiting the growth of cancers
SK14098A3 (en) Use of 1h-1,2,4-triazole derivatives for inhibiting the growth of cancers
US5902804A (en) Pharmaceutical composition for inhibiting the growth of viruses and cancers
KR19990022617A (ko) 백혈병 치료용 약제의 제조를 위한 벤즈이미다졸의 용도
RU2197964C2 (ru) Фармацевтическая композиция, композиция стандартной лекарственной формы и способ лечения злокачественных новообразований, опухолей и вирусных инфекций
MXPA97007808A (es) Una composicion farmaceutica que contiene n-clorofenilcarbamatos y n-clorofiniltiocarbamatos para inhibir el crecimiento de virus y canceres
MXPA97009712A (es) Uso de derivados de 1,2,4-triazol para la manufactura de un medicamento para el tratamiento de canceres
MXPA97007811A (es) Una composicion farmaceutica que contiene n-clorofenilcarbamatos, n-clorofeniltiocarbamatos y derivados de n-fosfonoglicina para inhibir el crecimiento de canceres y virus en mamiferos
MXPA97007810A (es) Una composicion farmaceutica que contiene derivados de n-fosfonoglicina para inhibir el crecimientode virus y canceres