SK11902000A3 - Prostriedok s predĺženým uvoľňovaním pre antagonistu angiotenzínu ii, jeho príprava a použitie - Google Patents

Prostriedok s predĺženým uvoľňovaním pre antagonistu angiotenzínu ii, jeho príprava a použitie Download PDF

Info

Publication number: SK11902000A3
Authority: SK; Slovakia
Prior art keywords: compound; sustained release; acid; angiotensin; release composition
Prior art date: 1998-03-04

Application number

SK1190-2000A

Other languages

English (en)

Slovak (sk)

Inventor

Yasutaka Igari

Akira Saikawa

Yoshiyuki Inada

Shigeru Kamei

Original Assignee

Takeda Chemical Industries, Ltd.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-03-04

Filing date

1999-03-03

Publication date

2001-02-12

1999-03-03 Application filed by Takeda Chemical Industries, Ltd. filed Critical Takeda Chemical Industries, Ltd.

2001-02-12 Publication of SK11902000A3 publication Critical patent/SK11902000A3/sk

Links

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YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 description 1
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UQZIYBXSHAGNOE-XNSRJBNMSA-N stachyose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO[C@@H]3[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O3)O)O2)O)O1 UQZIYBXSHAGNOE-XNSRJBNMSA-N 0.000 description 1
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XWMXMWHHTIEXRE-UHFFFAOYSA-N thiadiazole 1-oxide Chemical group O=S1C=CN=N1 XWMXMWHHTIEXRE-UHFFFAOYSA-N 0.000 description 1
VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
229910052723 transition metal Inorganic materials 0.000 description 1
150000003624 transition metals Chemical class 0.000 description 1
238000013519 translation Methods 0.000 description 1
235000013337 tricalcium citrate Nutrition 0.000 description 1
150000003627 tricarboxylic acid derivatives Chemical class 0.000 description 1
PLSARIKBYIPYPF-UHFFFAOYSA-H trimagnesium dicitrate Chemical compound [Mg+2].[Mg+2].[Mg+2].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O PLSARIKBYIPYPF-UHFFFAOYSA-H 0.000 description 1
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XOOUIPVCVHRTMJ-UHFFFAOYSA-L zinc stearate Chemical compound [Zn+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O XOOUIPVCVHRTMJ-UHFFFAOYSA-L 0.000 description 1
NWONKYPBYAMBJT-UHFFFAOYSA-L zinc sulfate Chemical compound [Zn+2].[O-]S([O-])(=O)=O NWONKYPBYAMBJT-UHFFFAOYSA-L 0.000 description 1
229910000368 zinc sulfate Inorganic materials 0.000 description 1
229960001763 zinc sulfate Drugs 0.000 description 1
VRGNUPCISFMPEM-ZVGUSBNCSA-L zinc;(2r,3r)-2,3-dihydroxybutanedioate Chemical compound [Zn+2].[O-]C(=O)[C@H](O)[C@@H](O)C([O-])=O VRGNUPCISFMPEM-ZVGUSBNCSA-L 0.000 description 1
MCOGTQGPHPAUJN-UHFFFAOYSA-L zinc;2-hydroxyacetate Chemical compound [Zn+2].OCC([O-])=O.OCC([O-])=O MCOGTQGPHPAUJN-UHFFFAOYSA-L 0.000 description 1
BOVNWDGXGNVNQD-UHFFFAOYSA-L zinc;2-hydroxybenzenesulfonate Chemical compound [Zn+2].OC1=CC=CC=C1S([O-])(=O)=O.OC1=CC=CC=C1S([O-])(=O)=O BOVNWDGXGNVNQD-UHFFFAOYSA-L 0.000 description 1
JDLYKQWJXAQNNS-UHFFFAOYSA-L zinc;dibenzoate Chemical compound [Zn+2].[O-]C(=O)C1=CC=CC=C1.[O-]C(=O)C1=CC=CC=C1 JDLYKQWJXAQNNS-UHFFFAOYSA-L 0.000 description 1
MLVWCBYTEFCFSG-UHFFFAOYSA-L zinc;dithiocyanate Chemical compound [Zn+2].[S-]C#N.[S-]C#N MLVWCBYTEFCFSG-UHFFFAOYSA-L 0.000 description 1
FYGDTMLNYKFZSV-BYLHFPJWSA-N β-1,4-galactotrioside Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@H](CO)O[C@@H](O[C@@H]2[C@@H](O[C@@H](O)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O FYGDTMLNYKFZSV-BYLHFPJWSA-N 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Inorganic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Heart & Thoracic Surgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Cardiology (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Plural Heterocyclic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

SK1190-2000A 1998-03-04 1999-03-03 Prostriedok s predĺženým uvoľňovaním pre antagonistu angiotenzínu ii, jeho príprava a použitie SK11902000A3 (sk)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP5236698		1998-03-04
PCT/JP1999/001011 WO1999044590A1 (en)	1998-03-04	1999-03-03	Sustained-release preparation for aii antagonist, production and use thereof

Publications (1)

Publication Number	Publication Date
SK11902000A3 true SK11902000A3 (sk)	2001-02-12

Family

ID=12912818

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK1190-2000A SK11902000A3 (sk)	1998-03-04	1999-03-03	Prostriedok s predĺženým uvoľňovaním pre antagonistu angiotenzínu ii, jeho príprava a použitie

Country Status (21)

Country	Link
US (2)	US6589547B1 (et)
EP (1)	EP1058541B1 (et)
KR (1)	KR20010086245A (et)
CN (1)	CN1291888A (et)
AT (1)	ATE258430T1 (et)
AU (1)	AU2745199A (et)
BR (1)	BR9908474A (et)
CA (1)	CA2318446C (et)
DE (1)	DE69914460T2 (et)
EE (1)	EE200000499A (et)
ES (1)	ES2214013T3 (et)
HU (1)	HUP0101439A3 (et)
ID (1)	ID25640A (et)
IL (1)	IL137979A0 (et)
LT (1)	LT4800B (et)
LV (1)	LV12585B (et)
NO (1)	NO20004350L (et)
PL (1)	PL342684A1 (et)
SK (1)	SK11902000A3 (et)
WO (1)	WO1999044590A1 (et)
ZA (1)	ZA991706B (et)

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1999
- 1999-03-03 ID IDW20001680A patent/ID25640A/id unknown
- 1999-03-03 CN CN99803444A patent/CN1291888A/zh active Pending
- 1999-03-03 PL PL99342684A patent/PL342684A1/xx unknown
- 1999-03-03 HU HU0101439A patent/HUP0101439A3/hu unknown
- 1999-03-03 AT AT99907846T patent/ATE258430T1/de not_active IP Right Cessation
- 1999-03-03 ES ES99907846T patent/ES2214013T3/es not_active Expired - Lifetime
- 1999-03-03 KR KR1020007008919A patent/KR20010086245A/ko not_active Abandoned
- 1999-03-03 DE DE69914460T patent/DE69914460T2/de not_active Expired - Lifetime
- 1999-03-03 AU AU27451/99A patent/AU2745199A/en not_active Abandoned
- 1999-03-03 BR BR9908474-0A patent/BR9908474A/pt not_active IP Right Cessation
- 1999-03-03 EP EP99907846A patent/EP1058541B1/en not_active Expired - Lifetime
- 1999-03-03 EE EEP200000499A patent/EE200000499A/et unknown
- 1999-03-03 CA CA002318446A patent/CA2318446C/en not_active Expired - Fee Related
- 1999-03-03 SK SK1190-2000A patent/SK11902000A3/sk unknown
- 1999-03-03 WO PCT/JP1999/001011 patent/WO1999044590A1/en not_active Ceased
- 1999-03-03 ZA ZA9901706A patent/ZA991706B/xx unknown
- 1999-03-03 IL IL13797999A patent/IL137979A0/xx unknown
- 1999-03-09 US US09/601,986 patent/US6589547B1/en not_active Expired - Fee Related
2000
- 2000-08-16 LV LVP-00-110A patent/LV12585B/en unknown
- 2000-08-31 LT LT2000082A patent/LT4800B/lt not_active IP Right Cessation
- 2000-09-01 NO NO20004350A patent/NO20004350L/no unknown
2003
- 2003-05-22 US US10/443,308 patent/US7294344B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
HUP0101439A3 (en)	2002-09-30
IL137979A0 (en)	2001-10-31
LV12585A (en)	2000-12-20
BR9908474A (pt)	2000-12-05
US6589547B1 (en)	2003-07-08
HUP0101439A2 (hu)	2001-10-28
CN1291888A (zh)	2001-04-18
DE69914460T2 (de)	2004-10-28
CA2318446A1 (en)	1999-09-10
NO20004350L (no)	2000-10-03
CA2318446C (en)	2008-09-23
US20030198676A1 (en)	2003-10-23
LT2000082A (en)	2001-03-26
LT4800B (lt)	2001-06-25
WO1999044590A1 (en)	1999-09-10
ZA991706B (en)	2000-10-03
NO20004350D0 (no)	2000-09-01
ID25640A (id)	2000-10-19
ATE258430T1 (de)	2004-02-15
LV12585B (en)	2001-03-20
PL342684A1 (en)	2001-07-02
ES2214013T3 (es)	2004-09-01
AU2745199A (en)	1999-09-20
KR20010086245A (ko)	2001-09-10
EP1058541B1 (en)	2004-01-28
US7294344B2 (en)	2007-11-13
DE69914460D1 (de)	2004-03-04
EE200000499A (et)	2002-02-15
EP1058541A1 (en)	2000-12-13

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