SI2764008T1 - Postopek za pripravo estetrola - Google Patents

Postopek za pripravo estetrola

Info

Publication number: SI2764008T1
Authority: SI; Slovenia
Prior art keywords: estetrol; production
Prior art date: 2011-10-07

Application number

SI201230705A

Other languages

English (en)

Slovenian (sl)

Inventor

Jean-Claude Pascal

Original Assignee

Estetra S.P.R.L.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-10-07

Filing date

2012-10-05

Publication date

2016-10-28

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48043195&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI2764008(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2012-10-05 Application filed by Estetra S.P.R.L. filed Critical Estetra S.P.R.L.

2016-10-28 Publication of SI2764008T1 publication Critical patent/SI2764008T1/sl

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Steroid Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

SI201230705A 2011-10-07 2012-10-05 Postopek za pripravo estetrola SI2764008T1 (sl)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US201161544591P	2011-10-07	2011-10-07
EP11184278		2011-10-07
PCT/EP2012/069761 WO2013050553A1 (en)	2011-10-07	2012-10-05	Process for the production of estetrol
EP12778664.8A EP2764008B1 (en)	2011-10-07	2012-10-05	Process for the production of estetrol

Publications (1)

Publication Number	Publication Date
SI2764008T1 true SI2764008T1 (sl)	2016-10-28

Family

ID=48043195

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SI201230705A SI2764008T1 (sl)	2011-10-07	2012-10-05	Postopek za pripravo estetrola

Country Status (26)

Country	Link
US (1)	US8987484B2 (it)
EP (1)	EP2764008B1 (it)
JP (1)	JP6196625B2 (it)
KR (1)	KR102007874B1 (it)
CN (1)	CN103890001B (it)
AU (1)	AU2012320423C1 (it)
BR (1)	BR112014008196B8 (it)
CA (1)	CA2847813C (it)
CL (1)	CL2014000802A1 (it)
CY (1)	CY1118674T1 (it)
DK (1)	DK2764008T3 (it)
EA (1)	EA024003B1 (it)
ES (1)	ES2593316T3 (it)
HR (1)	HRP20161282T1 (it)
HU (1)	HUE028963T2 (it)
IN (1)	IN2014MN00841A (it)
LT (1)	LT2764008T (it)
ME (1)	ME02527B (it)
MX (1)	MX348917B (it)
PL (1)	PL2764008T3 (it)
PT (1)	PT2764008T (it)
RS (1)	RS55231B1 (it)
SG (1)	SG11201401282PA (it)
SI (1)	SI2764008T1 (it)
SM (1)	SMT201600375B (it)
WO (1)	WO2013050553A1 (it)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SI2714712T1 (sl)	2011-06-01	2016-11-30	Estetra S.P.R.L.	Postopek za proizvodnjo intermediatov estetrola
CN103703014A (zh)	2011-06-01	2014-04-02	埃斯特拉公司	用于产生雌四醇中间体的方法
EP2383279A1 (en)	2011-07-19	2011-11-02	Pantarhei Bioscience B.V.	Process for the preparation of estetrol
WO2013034780A2 (en) *	2012-12-20	2013-03-14	Crystal Pharma, S.A.U.	Process for the preparation of estetrol and related compounds
WO2015040051A1 (en)	2013-09-18	2015-03-26	Crystal Pharma, S.A.U.	Process for the preparation of estetrol
EP3310333B1 (en)	2015-06-18	2020-04-29	Estetra SPRL	Orodispersible dosage unit containing an estetrol component
MA44205B1 (fr)	2015-06-18	2021-04-30	Estetra Sprl	Comprimé orodispersible comprenant estetrol
SMT201800232T1 (it)	2015-06-18	2018-07-17	Mithra Pharmaceuticals S A	Unita' di dosaggio orodispersibile contenente un componente di estetrolo
HUE054551T2 (hu) *	2015-06-18	2021-09-28	Estetra Sprl	Ösztetrolt tartalmazó, szájban diszpergálódó tabletta
KR102712911B1 (ko)	2016-08-05	2024-10-04	에스테트라, 소시에떼 아 레스폰서빌리떼 리미떼	월경통 및 생리통의 관리방법
TWI801561B (zh)	2018-04-19	2023-05-11	比利時商依思特拉私人有限責任公司	化合物及其用於緩解絕經相關症狀的用途
JOP20200260A1 (ar)	2018-04-19	2019-10-19	Estetra Sprl	مركبات واستخداماتها للتخفيف من الأعراض المصاحبة لانقطاع الطمث
EP3647413A1 (en) *	2018-10-31	2020-05-06	Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas O.A., M.P. (CIEMAT)	Improvements for performing and facilitating the recovery after hematopoietic stem cell transplantation
HU231240B1 (hu)	2019-09-03	2022-04-28	Richter Gedeon Nyrt.	Ipari eljárás nagytisztaságú ösztetrol hatóanyag előállítására
CN116355031A (zh) *	2019-09-27	2023-06-30	工业化学有限公司	制备(15α,16α,17β)-雌-1,3,5(10)-三烯-3,15,16,17-四醇一水合物(雌四醇一水合物)的工艺
IT201900021879A1 (it)	2019-11-22	2021-05-22	Ind Chimica Srl	PROCESSO PER LA PREPARAZIONE DI (15α,16α,17β)-ESTRA-1,3,5(10)-TRIENE-3,15,16,17-TETROLO (ESTETROLO) ED INTERMEDI DI DETTO PROCESSO
IT201900017414A1 (it)	2019-09-27	2021-03-27	Ind Chimica Srl	Processo per la preparazione di (15α,16α,17β)-estra-1,3,5(10)-triene-3,15,16,17-tetrolo (Estetrolo) ed intermedi di detto processo
TWI893101B (zh)	2020-04-16	2025-08-11	比利時商埃斯特拉有限責任公司	具有降低之副作用之避孕組成物
IT202100019631A1 (it)	2021-07-23	2023-01-23	Newchem S P A	Metodo per produrre estetrolo e i suoi intermedi
WO2023021026A1 (en)	2021-08-17	2023-02-23	Aspen Oss B.V.	A synthetic pathway to estra-1,3,5(10)-triene-3,15a,16a,17b-tetrol
MX2024004003A (es)	2021-10-01	2024-04-22	Ind Chimica Srl	Proceso para preparar monohidrato de (15alfa,16alfa,17beta)-estra- 1,3,5(10)-trien-3,15,16,17-tetrol (estetrol).
GB2641673A (en)	2023-02-02	2025-12-10	Ind Chimica Srl	Process for preparing (15a,16a,17B)-estra-1,3,5(10)-triene-3,15,16,17-tetrol (Estetrol) monohydrate
TW202517240A (zh) *	2023-08-30	2025-05-01	比利時商艾斯特答有限責任公司	雌四醇中間物之製造方法
HUP2400151A1 (hu)	2024-02-28	2025-09-28	Richter Gedeon Nyrt	Ösztetrol-monohidrát kristályosítási eljárás
WO2025181200A1 (en)	2024-02-28	2025-09-04	Estetra Srl	Estetrol polymorphic form and production thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW548277B (en) *	1999-07-16	2003-08-21	Akzo Nobel Nv	Orally active androgens
CZ301376B6 (cs) *	1999-12-02	2010-02-03	N.V. Organon	Steroidní deriváty s androgenním úcinkem
DE60332754D1 (de)	2002-11-08	2010-07-08	Pantarhei Bioscience Bv	Synthese von oestetrol aus von oestron abgeleiteten steroiden
UA89964C2 (ru) *	2004-09-08	2010-03-25	Н.В. Органон	15β-ЗАМЕЩЕННЫЕ СТЕРОИДЫ, КОТОРЫЕ ИМЕЮТ СЕЛЕКТИВНУЮ ЭСТРОГЕННУЮ АКТИВНОСТЬ
CN103703014A (zh)	2011-06-01	2014-04-02	埃斯特拉公司	用于产生雌四醇中间体的方法
SI2714712T1 (sl)	2011-06-01	2016-11-30	Estetra S.P.R.L.	Postopek za proizvodnjo intermediatov estetrola
EP2383279A1 (en) *	2011-07-19	2011-11-02	Pantarhei Bioscience B.V.	Process for the preparation of estetrol

2012
- 2012-10-05 CN CN201280049319.2A patent/CN103890001B/zh active Active
- 2012-10-05 WO PCT/EP2012/069761 patent/WO2013050553A1/en not_active Ceased
- 2012-10-05 KR KR1020147007408A patent/KR102007874B1/ko active Active
- 2012-10-05 DK DK12778664.8T patent/DK2764008T3/en active
- 2012-10-05 EA EA201490713A patent/EA024003B1/ru unknown
- 2012-10-05 US US14/349,940 patent/US8987484B2/en active Active
- 2012-10-05 ES ES12778664.8T patent/ES2593316T3/es active Active
- 2012-10-05 PL PL12778664T patent/PL2764008T3/pl unknown
- 2012-10-05 CA CA2847813A patent/CA2847813C/en active Active
- 2012-10-05 BR BR112014008196A patent/BR112014008196B8/pt active IP Right Grant
- 2012-10-05 EP EP12778664.8A patent/EP2764008B1/en active Active
- 2012-10-05 LT LTEP12778664.8T patent/LT2764008T/lt unknown
- 2012-10-05 RS RS20160859A patent/RS55231B1/sr unknown
- 2012-10-05 JP JP2014533925A patent/JP6196625B2/ja active Active
- 2012-10-05 ME MEP-2016-229A patent/ME02527B/me unknown
- 2012-10-05 HR HRP20161282TT patent/HRP20161282T1/hr unknown
- 2012-10-05 MX MX2014003723A patent/MX348917B/es active IP Right Grant
- 2012-10-05 HU HUE12778664A patent/HUE028963T2/en unknown
- 2012-10-05 AU AU2012320423A patent/AU2012320423C1/en active Active
- 2012-10-05 SG SG11201401282PA patent/SG11201401282PA/en unknown
- 2012-10-05 PT PT127786648T patent/PT2764008T/pt unknown
- 2012-10-05 SI SI201230705A patent/SI2764008T1/sl unknown
2014
- 2014-04-02 CL CL2014000802A patent/CL2014000802A1/es unknown
- 2014-05-05 IN IN841MUN2014 patent/IN2014MN00841A/en unknown
2016
- 2016-10-10 CY CY20161101001T patent/CY1118674T1/el unknown
- 2016-10-17 SM SM201600375T patent/SMT201600375B/it unknown

Also Published As

Publication number	Publication date
EP2764008A1 (en)	2014-08-13
HRP20161282T1 (hr)	2016-11-18
US8987484B2 (en)	2015-03-24
AU2012320423A1 (en)	2014-03-20
CN103890001B (zh)	2016-05-04
PL2764008T3 (pl)	2017-04-28
AU2012320423C1 (en)	2018-01-25
PT2764008T (pt)	2016-11-10
SMT201600375B (it)	2017-01-10
HUE028963T2 (en)	2017-01-30
BR112014008196B1 (pt)	2020-10-20
CL2014000802A1 (es)	2014-11-14
EP2764008B1 (en)	2016-08-17
BR112014008196B8 (pt)	2020-12-15
RS55231B1 (sr)	2017-02-28
NZ621973A (en)	2015-08-28
DK2764008T3 (en)	2016-11-07
LT2764008T (lt)	2016-11-10
ME02527B (me)	2017-02-20
BR112014008196A2 (pt)	2017-04-18
KR102007874B1 (ko)	2019-08-06
JP2014528438A (ja)	2014-10-27
CY1118674T1 (el)	2017-07-12
MX2014003723A (es)	2014-10-13
HK1199882A1 (zh)	2015-07-24
WO2013050553A1 (en)	2013-04-11
JP6196625B2 (ja)	2017-09-13
EA201490713A1 (ru)	2014-07-30
CN103890001A (zh)	2014-06-25
KR20140083994A (ko)	2014-07-04
SG11201401282PA (en)	2014-05-29
IN2014MN00841A (it)	2015-07-03
MX348917B (es)	2017-07-04
EA024003B1 (ru)	2016-08-31
ES2593316T3 (es)	2016-12-07
CA2847813C (en)	2018-12-11
AU2012320423B2 (en)	2017-02-09
CA2847813A1 (en)	2013-04-11
US20140243539A1 (en)	2014-08-28

Publication	Publication Date	Title
SG11201401282PA (en)	2014-05-29	Process for the production of estetrol
ZA201308446B (en)	2016-08-31	Process for the production of estetrol intermediates
PT2744768T (pt)	2016-07-13	Processo para a produção de clínquer de ternesite
PL2780307T3 (pl)	2017-02-28	Sposób wytwarzania fluorowodoroolefin
LT2734536T (lt)	2016-12-27	Estetrolio gamybos būdas
PL2531286T3 (pl)	2015-04-30	Sposób syntezy metanolu
ZA201308445B (en)	2015-07-29	Process for the production of estetrol intermediates
SG11201400939YA (en)	2014-07-30	Process for the preparation of methoxymelonal
EP2797868A4 (en)	2015-08-12	PROCESS FOR PRODUCING HEXANEDIOLS
IL236159A0 (en)	2015-02-01	Process for the production of methylbutanol
IL231645A (en)	2016-09-29	Process for making isoxazolyl - methoxy - nicotinic acids
IL232838A0 (en)	2014-08-03	Process for the production of triazinon-benzoxazinones
ZA201205844B (en)	2014-01-29	Process for the production of anhydrides
PL2744772T3 (pl)	2015-11-30	Sposób wytwarzania sewofluranu
HUE044066T2 (hu)	2019-09-30	Eljárás metilén-difenil-diizocianát elõállítására
PL2681199T3 (pl)	2019-03-29	Sposób wytwarzania (-)-hupercyny A
SG11201403392UA (en)	2014-10-30	Process for the production of alcohols
IL228900A0 (en)	2013-12-31	A process for the preparation of hexamethylenediamine
SG11201401492RA (en)	2014-08-28	Process for making esters
ZA201403104B (en)	2016-07-27	Process for the preparation of higher alcohols
PL2689069T3 (pl)	2017-04-28	Proces produkcji podsypki (balastu)
SG11201403380UA (en)	2014-09-26	Process for the production of alcohols
PL394378A1 (pl)	2012-10-08	Sposób otrzymywania E-2-amino-4-nitrostilbenów
PL394420A1 (pl)	2012-10-08	Sposób wytwarzania dilauroilofluoresceiny
IL229602A0 (en)	2014-01-30	Method for the production of fluoromethyl esters of androstene-17-beta carboxylic acids