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SG48053A1 - Improved methods for synthesis - Google Patents

Improved methods for synthesis

Info

Publication number
SG48053A1
SG48053A1 SG1996006672A SG1996006672A SG48053A1 SG 48053 A1 SG48053 A1 SG 48053A1 SG 1996006672 A SG1996006672 A SG 1996006672A SG 1996006672 A SG1996006672 A SG 1996006672A SG 48053 A1 SG48053 A1 SG 48053A1
Authority
SG
Singapore
Prior art keywords
synthesis
improved methods
methods
improved
Prior art date
Application number
SG1996006672A
Other languages
English (en)
Inventor
Arne Elof Brandstrom
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of SG48053A1 publication Critical patent/SG48053A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
SG1996006672A 1990-06-07 1991-06-05 Improved methods for synthesis SG48053A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9002043A SE9002043D0 (sv) 1990-06-07 1990-06-07 Improved method for synthesis

Publications (1)

Publication Number Publication Date
SG48053A1 true SG48053A1 (en) 1998-04-17

Family

ID=20379708

Family Applications (1)

Application Number Title Priority Date Filing Date
SG1996006672A SG48053A1 (en) 1990-06-07 1991-06-05 Improved methods for synthesis

Country Status (41)

Country Link
US (1) US5386032A (xx)
EP (1) EP0533752B1 (xx)
JP (1) JP2993122B2 (xx)
KR (1) KR0178045B1 (xx)
CN (1) CN1040536C (xx)
AP (1) AP216A (xx)
AT (1) ATE162790T1 (xx)
AU (1) AU640246B2 (xx)
BG (1) BG61265B1 (xx)
CA (1) CA2083605C (xx)
CZ (1) CZ279928B6 (xx)
DE (1) DE69128832T2 (xx)
DK (1) DK0533752T3 (xx)
DZ (1) DZ1504A1 (xx)
EG (1) EG19392A (xx)
ES (1) ES2113378T3 (xx)
FI (1) FI102967B (xx)
GR (1) GR3026642T3 (xx)
HR (1) HRP920770B1 (xx)
HU (1) HU214323B (xx)
IE (1) IE911845A1 (xx)
IL (1) IL98274A (xx)
IS (1) IS1752B (xx)
LT (1) LT3584B (xx)
LV (1) LV10271B (xx)
MA (1) MA22171A1 (xx)
NO (1) NO300541B1 (xx)
NZ (1) NZ238224A (xx)
PL (1) PL165433B1 (xx)
PT (1) PT97873B (xx)
RO (1) RO111366B1 (xx)
RU (1) RU2061693C1 (xx)
SA (1) SA91120027B1 (xx)
SE (1) SE9002043D0 (xx)
SG (1) SG48053A1 (xx)
SK (1) SK278505B6 (xx)
TN (1) TNSN91042A1 (xx)
UA (1) UA32524C2 (xx)
WO (1) WO1991018895A1 (xx)
YU (1) YU47570B (xx)
ZA (1) ZA913779B (xx)

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US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US6699885B2 (en) 1996-01-04 2004-03-02 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and methods of using same
US6645988B2 (en) * 1996-01-04 2003-11-11 Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
SE508669C2 (sv) * 1996-04-26 1998-10-26 Astra Ab Nytt förfarande
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SE510666C2 (sv) * 1996-12-20 1999-06-14 Astra Ab Nya Kristallmodifikationer
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SE510650C2 (sv) * 1997-05-30 1999-06-14 Astra Ab Ny förening
SE510643C2 (sv) * 1997-06-27 1999-06-14 Astra Ab Termodynamiskt stabil omeprazol natrium form B
ES2137862B1 (es) * 1997-07-31 2000-09-16 Intexim S A Preparacion farmaceutica oral que comprende un compuesto de actividad antiulcerosa y procedimiento para su obtencion.
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SE9704183D0 (sv) 1997-11-14 1997-11-14 Astra Ab New process
SI20019A (sl) * 1998-07-13 2000-02-29 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Izboljšan postopek sinteze 5-metoksi -2-/(4-metoksi-3,5-dimetil-2-piridil)metil/ sulfinil-1H-benzimidazola
US6191148B1 (en) 1998-08-11 2001-02-20 Merck & Co., Inc. Omerazole process and compositions thereof
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US6733778B1 (en) 1999-08-27 2004-05-11 Andrx Pharmaceuticals, Inc. Omeprazole formulation
UA72748C2 (en) * 1998-11-10 2005-04-15 Astrazeneca Ab A novel crystalline form of omeprazole
IL142703A (en) 1998-11-10 2006-04-10 Astrazeneca Ab Crystalline form of omeprazole
US6362202B1 (en) 1999-03-02 2002-03-26 Sepracor Inc. Methods and compositions using (−) norcisapride in combination with proton pump inhibitors or H2 receptor antagonists
US6353005B1 (en) 1999-03-02 2002-03-05 Sepracor, Inc. Method and compositions using (+) norcisapride in combination with proton pump inhibitors or H2 receptor antagonist
US6268385B1 (en) 1999-08-26 2001-07-31 Robert R. Whittle Dry blend pharmaceutical formulations
US6316020B1 (en) 1999-08-26 2001-11-13 Robert R. Whittle Pharmaceutical formulations
US6780880B1 (en) 1999-08-26 2004-08-24 Robert R. Whittle FT-Raman spectroscopic measurement
US6369087B1 (en) 1999-08-26 2002-04-09 Robert R. Whittle Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6312712B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Method of improving bioavailability
US6326384B1 (en) 1999-08-26 2001-12-04 Robert R. Whittle Dry blend pharmaceutical unit dosage form
US6262086B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Pharmaceutical unit dosage form
US6262085B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6312723B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Pharmaceutical unit dosage form
RU2247120C2 (ru) * 1999-10-28 2005-02-27 Грюненталь Гмбх Способ получения противоязвенных терапевтических средств
DE19951960C2 (de) 1999-10-28 2002-06-27 Gruenenthal Gmbh Verfahren zur Herstellung als Ulkustherapeutika geeigneter Benzimidazol-Derivate
JP2004524303A (ja) 2001-02-02 2004-08-12 テバ ファーマシューティカル インダストリーズ リミティド 置換された２−（２−ピリジルメチル）スルフィニル−１ｈ−ベンゾイミダゾール類の製造方法
KR100783020B1 (ko) * 2001-03-23 2007-12-07 동아제약주식회사 2-메틸클로라이드 피리딘 유도체 및 이를 이용한 벤즈이미다졸 유도체의 제조 방법
CA2450433C (en) * 2001-07-16 2010-05-25 Janssen Pharmaceutica N.V. Improved process for preparing benzimidazole-type compounds
JP2005521662A (ja) * 2002-01-25 2005-07-21 サンタラス インコーポレイティッド プロトンポンプ阻害剤の経粘膜送達
SE0203092D0 (en) 2002-10-18 2002-10-18 Astrazeneca Ab Method for the synthesis of a benzimidazole compound
WO2004073654A2 (en) * 2003-02-20 2004-09-02 Santarus, Inc. A novel formulation, omeprazole antacid complex-immediate release for rapid and sustained supression of gastric acid
US8993599B2 (en) * 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
MXPA06000529A (es) * 2003-07-18 2006-08-11 Santarus Inc Formulaciones farmaceuticas utiles para inhibir la secrecion de acido y metodos para elaborarlas y utilizarlas.
CA2531566C (en) * 2003-07-18 2013-05-07 Santarus, Inc. Pharmaceutical formulation and method for treating acid-caused gastrointestinal disorders
US20070292498A1 (en) * 2003-11-05 2007-12-20 Warren Hall Combinations of proton pump inhibitors, sleep aids, buffers and pain relievers
US8815916B2 (en) * 2004-05-25 2014-08-26 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8906940B2 (en) * 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
EP2264025B1 (en) 2004-09-13 2013-11-06 Takeda Pharmaceutical Company Limited Method for producing lansoprazole
WO2006040635A1 (en) * 2004-10-11 2006-04-20 Ranbaxy Laboratories Limited Processes for the preparation of substituted sulfoxides
KR100641534B1 (ko) 2005-07-28 2006-11-01 한미약품 주식회사 에스오메프라졸 및 그의 염의 제조방법
EP2998288B1 (en) 2005-12-01 2022-08-24 ACADIA Pharmaceuticals Inc. Substituted phenethylamines with serotoninergic and/or norepinephrinergic activity
EP1801110A1 (en) 2005-12-22 2007-06-27 KRKA, tovarna zdravil, d.d., Novo mesto Esomeprazole arginine salt
WO2007129328A2 (en) * 2006-05-09 2007-11-15 Cadila Healthcare Limited Process for preparing 2-[pyridinyl]sulfinyl-substituted benzimidazoles
US20090092658A1 (en) * 2007-10-05 2009-04-09 Santarus, Inc. Novel formulations of proton pump inhibitors and methods of using these formulations
EP2114919A2 (en) 2007-01-31 2009-11-11 Krka Tovarna Zdravil, D.D., Novo Mesto Process for the preparation of optically pure omeprazole via salt formation with a chiral amine or treatment with an entiomer converting enzyme and chromatographic seperation
DK2125698T3 (en) 2007-03-15 2016-11-07 Auspex Pharmaceuticals Inc Deuterated d9-VENLAFAXINE
CN102066396B (zh) * 2008-03-31 2014-03-12 科学与工业研究委员会 用作抗胃液分泌或抗溃疡剂的药物组合物
WO2010134099A1 (en) 2009-05-21 2010-11-25 Cadila Healthcare Limited One pot process for preparing omeprazole and related compounds
CN102786513A (zh) * 2011-05-18 2012-11-21 中国医学科学院药物研究所 奥美拉唑晶e型物质及制备方法与在药品和保健品中应用
WO2013108068A1 (en) 2012-01-21 2013-07-25 Jubilant Life Sciences Limited Process for the preparation of 2-pyridinylmethylsulfinyl benzimidazoles, their analogs and optically active enantiomers
US12364721B2 (en) 2019-09-24 2025-07-22 Prolacta Bioscience, Inc. Compositions and methods for treatment of inflammatory and immune diseases

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IN148930B (xx) * 1977-09-19 1981-07-25 Hoffmann La Roche
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4307102A (en) * 1981-02-19 1981-12-22 Sterling Drug Inc. Phenanthro[2,3-c]pyrazole
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
ZW4585A1 (en) * 1984-04-19 1985-11-20 Hoffmann La Roche Imidazole derivatives
IL76839A (en) * 1984-10-31 1988-08-31 Byk Gulden Lomberg Chem Fab Picoline derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
SE8500996D0 (sv) * 1985-03-01 1985-03-01 Haessle Ab Method of treatment
SE8600658D0 (sv) * 1986-02-14 1986-02-14 Haessle Ab Novel composition of matter
FI91754C (fi) * 1986-12-02 1994-08-10 Tanabe Seiyaku Co Analogiamenetelmä lääkeaineena käyttökelpoisen imidatsolijohdannaisen valmistamiseksi
DE3722810A1 (de) * 1987-07-10 1989-01-19 Hoechst Ag Substituierte benzimidazole, verfahren zu deren herstellung, diese enthaltende pharmazeutische zubereitungen und deren verwendung
SE9002206D0 (sv) * 1990-06-20 1990-06-20 Haessle Ab New compounds
NZ244301A (en) * 1991-09-20 1994-08-26 Merck & Co Inc Preparation of 2-pyridylmethylsulphinylbenzimidazole and pyridoimidazole derivatives from the corresponding sulphenyl compounds

Also Published As

Publication number Publication date
HK1003831A1 (en) 1998-11-06
NO924682L (no) 1992-12-04
TNSN91042A1 (fr) 1992-10-25
HU9203855D0 (en) 1993-03-29
HU214323B (hu) 1998-03-02
HUT63408A (en) 1993-08-30
GR3026642T3 (en) 1998-07-31
YU99291A (sh) 1993-11-16
NZ238224A (en) 1993-11-25
AP9100274A0 (en) 1991-07-31
IL98274A (en) 1995-03-30
EP0533752B1 (en) 1998-01-28
DK0533752T3 (da) 1998-06-02
MA22171A1 (fr) 1991-12-31
PL165433B1 (pl) 1994-12-30
CN1058211A (zh) 1992-01-29
FI925529A0 (fi) 1992-12-04
US5386032A (en) 1995-01-31
CN1040536C (zh) 1998-11-04
SK278505B6 (en) 1997-08-06
FI102967B1 (fi) 1999-03-31
LV10271B (en) 1995-04-20
RU2061693C1 (ru) 1996-06-10
HRP920770B1 (en) 2000-06-30
EP0533752A1 (en) 1993-03-31
HRP920770A2 (en) 1995-12-31
CA2083605A1 (en) 1991-12-08
AU640246B2 (en) 1993-08-19
NO300541B1 (no) 1997-06-16
LTIP1711A (en) 1995-07-25
ATE162790T1 (de) 1998-02-15
UA32524C2 (uk) 2001-02-15
SE9002043D0 (sv) 1990-06-07
ES2113378T3 (es) 1998-05-01
IS3711A7 (is) 1991-12-08
ZA913779B (en) 1992-02-26
DE69128832D1 (de) 1998-03-05
CZ279928B6 (cs) 1995-08-16
FI925529L (fi) 1992-12-04
BG61265B1 (en) 1997-04-30
DZ1504A1 (fr) 2004-09-13
JPH05507699A (ja) 1993-11-04
SA91120027B1 (ar) 2002-06-03
IS1752B (is) 2000-07-21
PT97873B (pt) 1998-10-30
KR0178045B1 (en) 1999-03-20
BG97146A (bg) 1993-12-24
EG19392A (en) 1995-06-29
AP216A (en) 1992-09-02
JP2993122B2 (ja) 1999-12-20
LV10271A (lv) 1994-10-20
AU8080791A (en) 1991-12-31
LT3584B (en) 1995-12-27
NO924682D0 (no) 1992-12-04
WO1991018895A1 (en) 1991-12-12
FI102967B (fi) 1999-03-31
IL98274A0 (en) 1992-06-21
PT97873A (pt) 1992-04-30
RO111366B1 (ro) 1996-09-30
YU47570B (sh) 1995-10-03
DE69128832T2 (de) 1998-05-28
CS172691A3 (en) 1992-01-15
CA2083605C (en) 1998-12-08
IE911845A1 (en) 1991-12-18

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