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SE8604059D0 - A method of controlling the epimeric distribution in the preparation of 16,17-acetals of pregnane derivatives - Google Patents

A method of controlling the epimeric distribution in the preparation of 16,17-acetals of pregnane derivatives

Info

Publication number
SE8604059D0
SE8604059D0 SE8604059A SE8604059A SE8604059D0 SE 8604059 D0 SE8604059 D0 SE 8604059D0 SE 8604059 A SE8604059 A SE 8604059A SE 8604059 A SE8604059 A SE 8604059A SE 8604059 D0 SE8604059 D0 SE 8604059D0
Authority
SE
Sweden
Prior art keywords
acetals
preparation
controlling
hydrocarbon solvent
epimeric distribution
Prior art date
Application number
SE8604059A
Other languages
English (en)
Swedish (sv)
Inventor
E Jakupovic
R T Sourander
J U Stenhede
R P Svensson
Original Assignee
Astra Pharma Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Pharma Prod filed Critical Astra Pharma Prod
Priority to SE8604059A priority Critical patent/SE8604059D0/xx
Publication of SE8604059D0 publication Critical patent/SE8604059D0/xx
Priority to US07/096,598 priority patent/US4925933A/en
Priority to DE8787850282T priority patent/DE3774987D1/de
Priority to EP87850282A priority patent/EP0262108B1/en
Priority to AT87850282T priority patent/ATE70066T1/de
Priority to ES198787850282T priority patent/ES2026576T3/es
Priority to IL83994A priority patent/IL83994A/xx
Priority to JP62237588A priority patent/JP2668000B2/ja
Priority to KR1019870010561A priority patent/KR950014460B1/ko
Priority to FI874189A priority patent/FI90345C/fi
Priority to GR91401949T priority patent/GR3003332T3/el
Priority to HK46194A priority patent/HK46194A/en
Priority to CY179195A priority patent/CY1791A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SE8604059A 1986-09-25 1986-09-25 A method of controlling the epimeric distribution in the preparation of 16,17-acetals of pregnane derivatives SE8604059D0 (sv)

Priority Applications (13)

Application Number Priority Date Filing Date Title
SE8604059A SE8604059D0 (sv) 1986-09-25 1986-09-25 A method of controlling the epimeric distribution in the preparation of 16,17-acetals of pregnane derivatives
US07/096,598 US4925933A (en) 1986-09-25 1987-09-11 Method of controlling the epimeric distribution in the preparation of 16,17-acetals of pregnane derivatives
ES198787850282T ES2026576T3 (es) 1986-09-25 1987-09-18 Un metodo para controlar la distribucion epimera en la preparacion de 16,17-acetales o cetales de derivados de pregnano.
AT87850282T ATE70066T1 (de) 1986-09-25 1987-09-18 Verfahren zur kontrolle der epimerischen verteilung in der herstellung von pregnane-16,17- acetal oder ketal derivaten.
EP87850282A EP0262108B1 (en) 1986-09-25 1987-09-18 A method of controlling the empimeric distribution in the preparation of 16,17-acetals or ketals of pregnane derivatives
DE8787850282T DE3774987D1 (de) 1986-09-25 1987-09-18 Verfahren zur kontrolle der epimerischen verteilung in der herstellung von pregnane-16,17-acetal oder ketal derivaten.
IL83994A IL83994A (en) 1986-09-25 1987-09-23 Method of controlling the epimeric distribution in the preparation of 16,17-acetals of pregnane derivatives
JP62237588A JP2668000B2 (ja) 1986-09-25 1987-09-24 プレグナン誘導体の１６，１７−アセタール製造におけるエピマー分配の調整法
KR1019870010561A KR950014460B1 (ko) 1986-09-25 1987-09-24 프레그난 유도체의 16, 17-아세탈 또는 케탈의 제조에 있어서 에피머 분배를 조절하는 방법
FI874189A FI90345C (fi) 1986-09-25 1987-09-24 Epimeerisen jakaantumisen säätelymenetelmä pregnaanijohdannaisten 16,17-asetaalien valmistuksessa
GR91401949T GR3003332T3 (en) 1986-09-25 1991-12-12 A method of controlling the empimeric distribution in the preparation of 16,17-acetals or ketals of pregnane derivatives
HK46194A HK46194A (en) 1986-09-25 1994-05-12 A method of controlling the empimeric distribution in the preparation of 16,17-acetals or ketals of pregnane derivatives
CY179195A CY1791A (en) 1986-09-25 1995-10-20 A method of controlling the empimeric distribution in the preparation of 16,17-acetals or ketals of pregnane derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8604059A SE8604059D0 (sv) 1986-09-25 1986-09-25 A method of controlling the epimeric distribution in the preparation of 16,17-acetals of pregnane derivatives

Publications (1)

Publication Number Publication Date
SE8604059D0 true SE8604059D0 (sv) 1986-09-25

Family

ID=20365704

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8604059A SE8604059D0 (sv) 1986-09-25 1986-09-25 A method of controlling the epimeric distribution in the preparation of 16,17-acetals of pregnane derivatives

Country Status (13)

Country Link
US (1) US4925933A (ja)
EP (1) EP0262108B1 (ja)
JP (1) JP2668000B2 (ja)
KR (1) KR950014460B1 (ja)
AT (1) ATE70066T1 (ja)
CY (1) CY1791A (ja)
DE (1) DE3774987D1 (ja)
ES (1) ES2026576T3 (ja)
FI (1) FI90345C (ja)
GR (1) GR3003332T3 (ja)
HK (1) HK46194A (ja)
IL (1) IL83994A (ja)
SE (1) SE8604059D0 (ja)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8903219D0 (sv) * 1989-10-02 1989-10-02 Astra Ab Process for the manufacture of budesonide
GR1001529B (el) * 1990-09-07 1994-03-31 Elmuquimica Farm Sl Μέ?οδος για την λήψη νέων 21-εστέρων της 16-17-ακετάλης της πρ να-1,4-διενο-3,20-διόνης.
SE9100341D0 (sv) * 1991-02-04 1991-02-04 Astra Ab Novel steroids
FR2675146A1 (fr) * 1991-04-10 1992-10-16 Roussel Uclaf Nouveaux derives sterouides de la pregna-1,4-diene-3,20-dione, leur preparation, leur application a la preparation de derives 16,17-methylene dioxy substitues et nouveaux intermediaires.
GB9423919D0 (en) * 1994-11-26 1995-01-11 Rhone Poulenc Rorer Ltd Chemical process
DE19635498A1 (de) * 1996-09-03 1998-03-26 Byk Gulden Lomberg Chem Fab Verfahren zur Epimerenanreicherung
IT1291288B1 (it) * 1997-04-30 1999-01-07 Farmabios Srl Processo per la preparazione di 16,17 acetali di derivati pregnanici con controllo della distribuzione epimerica al c-22.
US6266556B1 (en) 1998-04-27 2001-07-24 Beth Israel Deaconess Medical Center, Inc. Method and apparatus for recording an electroencephalogram during transcranial magnetic stimulation
IT1302657B1 (it) * 1998-10-13 2000-09-29 Farmabios Srl Processo stereoselettivo per la preparazione di budesonide nella formadi epimero 22-r.
KR20070116185A (ko) * 2000-11-10 2007-12-06 니코메드 게엠베하 트랜스케탈화 반응에 의한16,17-[(시클로헥실메틸렌)비스(옥시)]-11,21-디히드록시-프레그나-1,4-디엔-3,20-디온 또는 이의 21-이소부티라트의제조방법
WO2003027134A1 (en) * 2001-09-25 2003-04-03 Pharmacia & Upjohn Company Stereoselective transacetalization of steroidal c-22 acetonide
AU2003291634A1 (en) * 2002-10-08 2004-05-04 Sepracor Inc. Fatty acid modified forms of glucocorticoids and their use as anti-inflammatory
JP2009512733A (ja) * 2005-11-02 2009-03-26 シコール インコーポレイティド シクレソニドの改良された製造法
US20070232578A1 (en) * 2006-02-15 2007-10-04 Pierluigi Rossetto Crystalline forms of ciclesonide
US10233210B2 (en) 2015-01-30 2019-03-19 Coral Drugs Pvt. Ltd. Process for preparation of glucocorticoid steroids
EP4659809A2 (en) 2016-11-08 2025-12-10 Regeneron Pharmaceuticals, Inc. Steroids and protein-conjugates thereof
US11491237B2 (en) 2017-05-18 2022-11-08 Regeneron Pharmaceuticals, Inc. Cyclodextrin protein drug conjugates
MX2020004691A (es) 2017-11-07 2020-08-20 Regeneron Pharma Enlazadores hidrofilicos para conjugados anticuerpo-farmaco.
CN112004557B (zh) 2018-01-08 2024-07-30 里珍纳龙药品有限公司 类固醇类化合物及其抗体偶联物
KR20210008008A (ko) 2018-05-09 2021-01-20 리제너론 파마슈티칼스 인코포레이티드 항-msr1 항체 및 이의 사용 방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE378109B (ja) * 1972-05-19 1975-08-18 Bofors Ab
SE378110B (ja) * 1972-05-19 1975-08-18 Bofors Ab
SE8008524L (sv) * 1980-12-04 1982-06-05 Draco Ab 4-pregnen-derivat, ett forfarande for deras framstellning, beredning och metod for behandling av inflammatoriska tillstand
IT1196142B (it) * 1984-06-11 1988-11-10 Sicor Spa Procedimento per la preparazione di 16,17-acetali di derivati pregnanici e nuovi composti ottenuti

Also Published As

Publication number Publication date
US4925933A (en) 1990-05-15
FI90345C (fi) 1994-01-25
CY1791A (en) 1995-10-20
EP0262108B1 (en) 1991-12-04
JP2668000B2 (ja) 1997-10-27
EP0262108A1 (en) 1988-03-30
KR880003969A (ko) 1988-06-01
FI90345B (fi) 1993-10-15
IL83994A0 (en) 1988-02-29
GR3003332T3 (en) 1993-02-17
FI874189L (fi) 1988-03-26
IL83994A (en) 1992-02-16
HK46194A (en) 1994-05-20
DE3774987D1 (de) 1992-01-16
KR950014460B1 (ko) 1995-11-28
ATE70066T1 (de) 1991-12-15
JPS6393795A (ja) 1988-04-25
ES2026576T3 (es) 1992-05-01
FI874189A0 (fi) 1987-09-24

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