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SE8004002L - Terapeutiskt anvendbara tetralinderivat - Google Patents

Terapeutiskt anvendbara tetralinderivat

Info

Publication number
SE8004002L
SE8004002L SE8004002A SE8004002A SE8004002L SE 8004002 L SE8004002 L SE 8004002L SE 8004002 A SE8004002 A SE 8004002A SE 8004002 A SE8004002 A SE 8004002A SE 8004002 L SE8004002 L SE 8004002L
Authority
SE
Sweden
Prior art keywords
carbon atoms
compounds
alkyl group
group
therapeutically applicable
Prior art date
Application number
SE8004002A
Other languages
English (en)
Swedish (sv)
Inventor
Folke Lars-Erik Arvidsson
Per Arvid Emil Carlsson
Uli Alf Hacksell
John Stephan Mikael Hjort
Per Lennart Lindberg
John Lars Gunnar Nilsson
Domingo Sanchez
Hakan Vilhelm Wikstrom
Original Assignee
Arvidsson Folke Lars Erik
Per Arvid Emil Carlsson
Hacksell Uli A
John Stephan Mikael Hjort
Per Lennart Lindberg
John Lars Gunnar Nilsson
Domingo Sanchez
Hakan Vilhelm Wikstrom
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arvidsson Folke Lars Erik, Per Arvid Emil Carlsson, Hacksell Uli A, John Stephan Mikael Hjort, Per Lennart Lindberg, John Lars Gunnar Nilsson, Domingo Sanchez, Hakan Vilhelm Wikstrom filed Critical Arvidsson Folke Lars Erik
Priority to SE8004002A priority Critical patent/SE8004002L/xx
Priority to AU71797/81A priority patent/AU7179781A/en
Priority to JP56501683A priority patent/JPS57500694A/ja
Priority to FI822226A priority patent/FI822226L/fi
Priority to PCT/SE1981/000155 priority patent/WO1981003491A1/en
Priority to EP81850092A priority patent/EP0041488A1/en
Priority to ES502565A priority patent/ES8400730A1/es
Publication of SE8004002L publication Critical patent/SE8004002L/xx
Priority to DK32982A priority patent/DK32982A/da
Priority to NO820255A priority patent/NO820255L/no
Priority to ES512401A priority patent/ES512401A0/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/43Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C211/57Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings being part of condensed ring systems of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/48Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
    • C07C215/50Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups with amino groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/58Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms with amino groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/26Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C219/28Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SE8004002A 1980-05-29 1980-05-29 Terapeutiskt anvendbara tetralinderivat SE8004002L (sv)

Priority Applications (10)

Application Number Priority Date Filing Date Title
SE8004002A SE8004002L (sv) 1980-05-29 1980-05-29 Terapeutiskt anvendbara tetralinderivat
AU71797/81A AU7179781A (en) 1980-05-29 1981-05-26 Therapeutically useful tetralin derivatives
JP56501683A JPS57500694A (es) 1980-05-29 1981-05-26
FI822226A FI822226L (fi) 1980-05-29 1981-05-26 Terapeutiskt anvaendbara tetralinderivat
PCT/SE1981/000155 WO1981003491A1 (en) 1980-05-29 1981-05-26 Therapeutically useful tetralin derivatives
EP81850092A EP0041488A1 (en) 1980-05-29 1981-05-26 Therapeutically useful tetralin derivatives
ES502565A ES8400730A1 (es) 1980-05-29 1981-05-28 Un procedimiento para preparar derivados de tetralina
DK32982A DK32982A (da) 1980-05-29 1982-01-26 Terapeutisk nyttige tetralinderivater
NO820255A NO820255L (no) 1980-05-29 1982-01-28 Terapeutisk nyttige tetralin-derivater.
ES512401A ES512401A0 (es) 1980-05-29 1982-05-20 "un procedimiento para preparar derivados de tetralina".

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8004002A SE8004002L (sv) 1980-05-29 1980-05-29 Terapeutiskt anvendbara tetralinderivat

Publications (1)

Publication Number Publication Date
SE8004002L true SE8004002L (sv) 1981-11-30

Family

ID=20341076

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8004002A SE8004002L (sv) 1980-05-29 1980-05-29 Terapeutiskt anvendbara tetralinderivat

Country Status (7)

Country Link
EP (1) EP0041488A1 (es)
JP (1) JPS57500694A (es)
DK (1) DK32982A (es)
ES (2) ES8400730A1 (es)
NO (1) NO820255L (es)
SE (1) SE8004002L (es)
WO (1) WO1981003491A1 (es)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4448990A (en) * 1982-11-16 1984-05-15 Eli Lilly And Company Hydroxyaminotetralincarboxamides
US4743618A (en) * 1983-01-03 1988-05-10 Nelson Research & Development Co. Substituted 2-aminotetralins
GB2157950B (en) * 1984-05-04 1988-11-02 Nelson Res & Dev Selective d-2 dopamine receptor agonist
DE3479314D1 (en) * 1984-05-22 1989-09-14 Nelson Res & Dev Substituted 2-aminotetralins and processes for synthesis
DE3718317A1 (de) * 1986-12-10 1988-06-16 Bayer Ag Substituierte basische 2-aminotetraline
US5153225A (en) * 1986-12-10 1992-10-06 Bayer Aktiengesellschaft Substituted basic 2-aminotetralin in pharmaceuticals
DE3719924A1 (de) * 1986-12-22 1988-06-30 Bayer Ag 8-substituierte 2-aminotetraline
US4845221A (en) * 1988-04-15 1989-07-04 American Home Products Corporation Serotonergic substituted piperazinyl tetralins
US5162375A (en) * 1988-05-06 1992-11-10 Beecham Group P.L.C. Treatment of neuronal degeneration with 5HT1A agonists
GB8810748D0 (en) * 1988-05-06 1988-06-08 Beecham Wuelfing Gmbh & Co Kg Novel treatment
US5026707A (en) * 1988-05-23 1991-06-25 Eli Lilly And Company Ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes
DE3832571A1 (de) * 1988-09-24 1990-05-31 Boehringer Ingelheim Kg Verwendung von 2,7-diamino-1,2,3,4-tetrahydronaphthalinen als arzneimittel, neue 2,7-diamino-1,2,3,4-tetrahydronaphthaline sowie verfahren zu ihrer herstellung
US4992465A (en) * 1988-09-27 1991-02-12 Ciba-Geigy Corporation 3-amino-dihydro-(1)-benzopyrans
US5225596A (en) * 1989-01-09 1993-07-06 The Upjohn Company Halo substituted aminotetralins
JP2868897B2 (ja) * 1989-01-09 1999-03-10 ジ・アップジョン・カンパニー ハロゲン置換アミノテトラリン類
IL109647A (en) * 1989-02-27 1997-04-15 Lilly Co Eli Intermediate compounds for ring-substituted 2-amino-1, 2, 3, 4-tetra- hydronaphthalenes and 3-aminochromanes
GB8907865D0 (en) * 1989-04-07 1989-05-24 Wyeth John & Brother Ltd Tetrahydroquinoline derivatives
US5234945A (en) * 1989-05-09 1993-08-10 Whitby Research, Inc. Method of producing body weight and food intake using a dopamine D2 receptor agonist
SE8901889D0 (sv) * 1989-05-26 1989-05-26 Astra Ab Novel 8-substituted-2-aminotetralines
WO1990015047A1 (en) * 1989-05-31 1990-12-13 The Upjohn Company Therapeutically useful 2-aminotetralin derivatives
DE3919624A1 (de) * 1989-06-15 1990-12-20 Boehringer Ingelheim Kg Neue 2,5-diaminotetraline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
SE8904127D0 (sv) * 1989-12-07 1989-12-07 Astra Ab New biocyclic amino-substituted compounds
EP0450238A1 (en) * 1990-03-30 1991-10-09 Merrell Dow Pharmaceuticals Inc. Novel compounds for the treatment of migraine
US5194439A (en) * 1990-04-06 1993-03-16 John Wyeth & Brother Limited N-(2,3-dihydro-1,4-benzodioxinyl)-N-substituted aminopyrido-fused cycloalkanes
DE69124868T2 (de) * 1990-08-15 1997-07-10 Lilly Co Eli Ring-substituierte 2-Amino-1,2,3,4-tetra-hydronaphthaline, 3-Aminochromane und 3-Aminothiochromane
CA2090321C (en) * 1990-10-12 2002-04-09 Chiu-Hong Lin Therapeutically useful 2-aminotetralin derivatives
ZA92767B (en) * 1991-02-08 1993-08-03 Lilly Co Eli Ring-substituted 2-amino-1,2,3,4-tetra-hydronaphthalenes and 3-aminochromanes.
PT100639A (pt) * 1991-06-27 1993-09-30 Univ Virginia Commonwealth Metodo para o tratamento terapeutico com compostos que sao ligandos ao receptor sigma e compostos ai utilizados, nomeadamente derivados fenilalquil-amina, aminotetralina,piperazina e piperidina
US5824680A (en) * 1991-08-31 1998-10-20 Bayer Aktiengesellschaft Ipsapirone for the treatment of alzheimer's disease by improving memory
TW239127B (es) * 1991-12-20 1995-01-21 Hoffmann La Roche
WO1995000131A1 (en) * 1993-06-23 1995-01-05 Cambridge Neuroscience, Incorporated Sigma receptor ligands and the use thereof
FR2707636B1 (fr) * 1993-06-29 1995-09-15 Inst Francais Du Petrole Composition sulfo-uréique résultant de l'action de l'urée sur une boue sulfurique d'origine pétrolière, procédé de préparation et utilisation comme source de matière fertilisante.
US7829587B2 (en) 2008-01-09 2010-11-09 Allergan, Inc. Substituted 2-aminotetralin derivatives as selective alpha 2B agonist
WO2009121872A2 (en) 2008-04-01 2009-10-08 Abbott Gmbh & Co. Kg Tetrahydroisoquinolines, pharmaceutical compositions containing them, and their use in therapy
MX2011003930A (es) * 2008-10-13 2011-05-03 Interquim Sa Procedimiento de obtencion de los compuestos opticamente activos (s)-(-)-2-(n-propilamino)-5-metoxitetralina y (s)-(-)-2-(n-propilamino)-5-hidroxitetralina.
AR075442A1 (es) 2009-02-16 2011-03-30 Abbott Gmbh & Co Kg Derivados de aminotetralina, composiciones farmaceuticas que las contienen y sus usos en terapia
EP2338873A1 (en) 2009-12-22 2011-06-29 Gmeiner, Peter New aminotetraline derivatives
DE102010020553A1 (de) 2010-05-14 2011-11-17 Bayer Schering Pharma Aktiengesellschaft Substituierte 8-Alkoxy-2-aminotetralin-Derivate und ihre Verwendung
US8877794B2 (en) 2010-08-13 2014-11-04 Abbott Laboratories Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy
US9051280B2 (en) 2010-08-13 2015-06-09 AbbVie Deutschland GmbH & Co. KG Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy
US8846743B2 (en) 2010-08-13 2014-09-30 Abbott Laboratories Aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy
US8883839B2 (en) 2010-08-13 2014-11-11 Abbott Laboratories Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy
US9045459B2 (en) 2010-08-13 2015-06-02 AbbVie Deutschland GmbH & Co. KG Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy
US9309200B2 (en) 2011-05-12 2016-04-12 AbbVie Deutschland GmbH & Co. KG Benzazepine derivatives, pharmaceutical compositions containing them, and their use in therapy
CN103889968A (zh) 2011-08-05 2014-06-25 艾伯维德国有限责任两合公司 氨基苯并二氢吡喃、氨基苯并二氢噻喃及氨基-1,2,3,4-四氢喹啉衍生物,包含这些化合物的药用组合物,及其在治疗中的用途
JP2014533675A (ja) 2011-11-18 2014-12-15 アッヴィ・ドイチュラント・ゲー・エム・ベー・ハー・ウント・コー・カー・ゲー N置換アミノベンゾシクロヘプテン、アミノテトラリン、アミノインダンおよびフェナルキルアミン誘導体、これらを含有する医薬組成物、および治療におけるこれらの使用
US9365512B2 (en) 2012-02-13 2016-06-14 AbbVie Deutschland GmbH & Co. KG Isoindoline derivatives, pharmaceutical compositions containing them, and their use in therapy
ES2603262T3 (es) 2012-07-20 2017-02-24 Bayer Pharma Aktiengesellschaft Ácidos aminoindano-carboxílicos y aminotetralin-carboxílicos sustituidos y su uso
PL2875003T3 (pl) 2012-07-20 2017-05-31 Bayer Pharma Aktiengesellschaft Nowe kwasy 5-aminotetrahydrochinolino-2-karboksylowe i ich zastosowanie
US9650334B2 (en) 2013-03-15 2017-05-16 Abbvie Inc. Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy
US9656955B2 (en) 2013-03-15 2017-05-23 Abbvie Inc. Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy
MX2016004936A (es) 2013-10-17 2016-12-20 Abbvie Deutschland Derivados de aminocromano, aminotiocromano y amino-1,2,3,4-tetrahi droquinilina, composiciones farmaceuticas que los contienen, y su uso en terapia.
CA2924699A1 (en) 2013-10-17 2015-04-23 AbbVie Deutschland GmbH & Co. KG Aminotetraline and aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy
EP4457215A1 (en) 2021-12-29 2024-11-06 Bayer Aktiengesellschaft Process for preparing (5s)-{[2-(4-carboxyphenyl)ethyl] 2-(2-{ 3-chloro-4'-(trifluoromethyl)biphenyl-4- yl]methoxy}phenyl)ethyl]aminol-5,6,7,8-tetrahydroquinoline-2-carboxylic acid and its crystalline forms for use as pharmaceutically active compound
AU2022424376A1 (en) 2021-12-29 2024-07-04 Bayer Aktiengesellschaft Treatment of cardiopulmonary disorders

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1440440A (en) * 1972-10-06 1976-06-23 Manuf Prod Pharma Tetrahydronaphthalene derivatives
US3969468A (en) * 1972-10-31 1976-07-13 Kyowa Hakko Kogyo Co., Ltd. 2-Amino-1,2,3,4-tetrahydronaphthalene derivatives
DK131775A (es) * 1974-03-28 1975-09-29 Wellcome Found
DE2752659A1 (de) * 1976-12-07 1978-06-08 Sandoz Ag Neue tetralinderivate, ihre herstellung und verwendung
DE2803582A1 (de) * 1978-01-27 1979-08-02 Sandoz Ag Neue tetralinderivate, ihre herstellung und verwendung
DE2816122A1 (de) * 1978-04-14 1979-10-25 Bayer Ag 1,8-diamino-1,2,3,4-tetrahydronaphthalin
JPS639500B2 (es) * 1978-07-14 1988-02-29 Amerikan Hosupitaru Sapurai Corp
DE3062971D1 (en) * 1979-09-14 1983-06-09 Sandoz Ag Derivatives of tetraline, their preparation and medicaments containing these compounds
US4536518A (en) * 1979-11-01 1985-08-20 Pfizer Inc. Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine
US4556676A (en) * 1979-11-01 1985-12-03 Pfizer Inc. Antidepressant derivatives of trans-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine

Also Published As

Publication number Publication date
NO820255L (no) 1982-01-28
ES502565A0 (es) 1983-11-01
JPS57500694A (es) 1982-04-22
ES8401443A1 (es) 1983-12-01
EP0041488A1 (en) 1981-12-09
ES8400730A1 (es) 1983-11-01
WO1981003491A1 (en) 1981-12-10
DK32982A (da) 1982-01-26
ES512401A0 (es) 1983-12-01

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