RU2013103334A - Композиции, содержащие экстракты echinacea angustifolia и zingiber officinale, которые полезны для уменьшения воспаления и периферической боли - Google Patents
Композиции, содержащие экстракты echinacea angustifolia и zingiber officinale, которые полезны для уменьшения воспаления и периферической боли Download PDFInfo
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- 239000000284 extract Substances 0.000 title claims abstract 9
- 239000000203 mixture Substances 0.000 title claims abstract 7
- 230000002093 peripheral effect Effects 0.000 title claims abstract 5
- 244000133098 Echinacea angustifolia Species 0.000 title claims 5
- 244000273928 Zingiber officinale Species 0.000 title claims 5
- 235000006886 Zingiber officinale Nutrition 0.000 title claims 5
- 235000014134 echinacea Nutrition 0.000 title claims 5
- 235000008397 ginger Nutrition 0.000 title claims 5
- 239000001841 zingiber officinale Substances 0.000 title claims 5
- 206010061218 Inflammation Diseases 0.000 title 1
- 230000004054 inflammatory process Effects 0.000 title 1
- KDSNLYIMUZNERS-UHFFFAOYSA-N 2-methylpropanamine Chemical class CC(C)CN KDSNLYIMUZNERS-UHFFFAOYSA-N 0.000 claims abstract 4
- 208000035143 Bacterial infection Diseases 0.000 claims abstract 4
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims abstract 4
- 206010017533 Fungal infection Diseases 0.000 claims abstract 4
- 208000007101 Muscle Cramp Diseases 0.000 claims abstract 4
- 208000031888 Mycoses Diseases 0.000 claims abstract 4
- 206010030113 Oedema Diseases 0.000 claims abstract 4
- 208000003251 Pruritus Diseases 0.000 claims abstract 4
- 206010040880 Skin irritation Diseases 0.000 claims abstract 4
- 208000022362 bacterial infectious disease Diseases 0.000 claims abstract 4
- 230000002538 fungal effect Effects 0.000 claims abstract 4
- NLDDIKRKFXEWBK-AWEZNQCLSA-N gingerol Chemical compound CCCCC[C@H](O)CC(=O)CCC1=CC=C(O)C(OC)=C1 NLDDIKRKFXEWBK-AWEZNQCLSA-N 0.000 claims abstract 4
- JZLXEKNVCWMYHI-UHFFFAOYSA-N gingerol Natural products CCCCC(O)CC(=O)CCC1=CC=C(O)C(OC)=C1 JZLXEKNVCWMYHI-UHFFFAOYSA-N 0.000 claims abstract 4
- 235000002780 gingerol Nutrition 0.000 claims abstract 4
- 230000002757 inflammatory effect Effects 0.000 claims abstract 4
- 239000000546 pharmaceutical excipient Substances 0.000 claims abstract 4
- 208000006934 radiodermatitis Diseases 0.000 claims abstract 4
- 230000036556 skin irritation Effects 0.000 claims abstract 4
- 231100000475 skin irritation Toxicity 0.000 claims abstract 4
- 206010028980 Neoplasm Diseases 0.000 claims abstract 3
- 201000011510 cancer Diseases 0.000 claims abstract 3
- 238000001959 radiotherapy Methods 0.000 claims abstract 3
- 241000196324 Embryophyta Species 0.000 claims abstract 2
- 229910002092 carbon dioxide Inorganic materials 0.000 claims abstract 2
- 239000001569 carbon dioxide Substances 0.000 claims abstract 2
- 238000000605 extraction Methods 0.000 claims abstract 2
- 239000003921 oil Substances 0.000 claims abstract 2
- 150000003904 phospholipids Chemical class 0.000 claims abstract 2
- 239000004094 surface-active agent Substances 0.000 claims abstract 2
- 238000011275 oncology therapy Methods 0.000 abstract 1
- 230000005855 radiation Effects 0.000 abstract 1
- 238000011200 topical administration Methods 0.000 abstract 1
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61K9/10—Dispersions; Emulsions
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Abstract
1. Комбинация липофильных экстрактовидля применения в лечении зуда, периферической боли, поверхностных или глубоких воспалительных и болезненных состояний, боли, связанной с мышечными спазмами, герпетической боли, радиационного дерматита, вызванного лучевой терапией рака, при наличии или отсутствии грибковых или бактериальных инфекций, отека и состояний раздражения кожи, включая состояния, обусловленные чрезмерным воздействием солнечного света.2. Комбинация по п.1, в которой экстракты обоих видов растений получают из корней или корневищ экстракцией сверхкритическим диоксидом углерода.3. Комбинация по пп.1 и 2, содержащая изобутиламиды изи гингерол изв массовых соотношениях, составляющих от 1:1 до 1:0,1.4. Комбинация по п.3, содержащая изобутиламиды изи гингерол изв массовом соотношении 1:0,5.5. Композиция, содержащая комбинацию липофильных экстрактовипо пп.1-4 вместе с физиологически совместимыми наполнителями и эксципиентами для применения в лечении зуда, периферической боли, поверхностных или глубоких воспалительных и болезненных состояний, боли, связанной с мышечными спазмами, герпетической боли, радиационного дерматита, вызванного лучевой терапией рака, при наличии или отсутствии грибковых или бактериальных инфекций, отека и состояний раздражения кожи, включая состояния, обусловленные чрезмерным воздействием солнечного света.6. Композиция по п.5, которая находится в форме, подходящей для местного введения.7. Композиция по пп.5-6, в которой экстракты приготовлены в маслах в присутствии поверхностно-активных веществ или фосфолипидов.
Claims (7)
1. Комбинация липофильных экстрактов Zingiber officinale и Echinacea angustifolia для применения в лечении зуда, периферической боли, поверхностных или глубоких воспалительных и болезненных состояний, боли, связанной с мышечными спазмами, герпетической боли, радиационного дерматита, вызванного лучевой терапией рака, при наличии или отсутствии грибковых или бактериальных инфекций, отека и состояний раздражения кожи, включая состояния, обусловленные чрезмерным воздействием солнечного света.
2. Комбинация по п.1, в которой экстракты обоих видов растений получают из корней или корневищ экстракцией сверхкритическим диоксидом углерода.
3. Комбинация по пп.1 и 2, содержащая изобутиламиды из Echinacea angustifolia и гингерол из Zingiber officinale в массовых соотношениях, составляющих от 1:1 до 1:0,1.
4. Комбинация по п.3, содержащая изобутиламиды из Echinacea angustifolia и гингерол из Zingiber officinale в массовом соотношении 1:0,5.
5. Композиция, содержащая комбинацию липофильных экстрактов Zingiber officinale и Echinacea angustifolia по пп.1-4 вместе с физиологически совместимыми наполнителями и эксципиентами для применения в лечении зуда, периферической боли, поверхностных или глубоких воспалительных и болезненных состояний, боли, связанной с мышечными спазмами, герпетической боли, радиационного дерматита, вызванного лучевой терапией рака, при наличии или отсутствии грибковых или бактериальных инфекций, отека и состояний раздражения кожи, включая состояния, обусловленные чрезмерным воздействием солнечного света.
6. Композиция по п.5, которая находится в форме, подходящей для местного введения.
7. Композиция по пп.5-6, в которой экстракты приготовлены в маслах в присутствии поверхностно-активных веществ или фосфолипидов.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI2010A001373A IT1401141B1 (it) | 2010-07-26 | 2010-07-26 | Formulazioni contenenti estratti di echinacea angustifolia e di zingiber officinale utili nella riduzione dell'infiammazione e del dolore periferico |
| ITMI2010A001373 | 2010-07-26 | ||
| PCT/EP2011/062421 WO2012013551A1 (en) | 2010-07-26 | 2011-07-20 | Formulations containing extracts of echinacea angustifolia and zingiber officinale which are useful in reducing inflammation and peripheral pain |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2013103334A true RU2013103334A (ru) | 2014-07-27 |
| RU2565436C2 RU2565436C2 (ru) | 2015-10-20 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2013103334/15A RU2565436C2 (ru) | 2010-07-26 | 2011-07-20 | КОМПОЗИЦИИ, СОДЕРЖАЩИЕ ЭКСТРАКТЫ Echinacea angustifolia И Zingiber officinale, КОТОРЫЕ ПОЛЕЗНЫ ДЛЯ УМЕНЬШЕНИЯ ВОСПАЛЕНИЯ И ПЕРИФЕРИЧЕСКОЙ БОЛИ |
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| US (2) | US9283259B2 (ru) |
| EP (1) | EP2598156B1 (ru) |
| JP (1) | JP5996534B2 (ru) |
| KR (1) | KR101812746B1 (ru) |
| CN (1) | CN103096907B (ru) |
| AR (1) | AR082342A1 (ru) |
| AU (1) | AU2011285025B2 (ru) |
| BR (1) | BR112013001838A2 (ru) |
| CA (1) | CA2806428C (ru) |
| CL (1) | CL2013000241A1 (ru) |
| DK (1) | DK2598156T3 (ru) |
| ES (1) | ES2477548T3 (ru) |
| HR (1) | HRP20140583T8 (ru) |
| IL (1) | IL224388A (ru) |
| IT (1) | IT1401141B1 (ru) |
| MX (1) | MX338951B (ru) |
| PL (1) | PL2598156T3 (ru) |
| PT (1) | PT2598156E (ru) |
| RU (1) | RU2565436C2 (ru) |
| SG (1) | SG187601A1 (ru) |
| SI (1) | SI2598156T1 (ru) |
| WO (1) | WO2012013551A1 (ru) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20121317A1 (it) * | 2012-07-27 | 2014-01-28 | Indena Spa | Composizioni per il trattamento della fatica oncologica |
| CA2904948A1 (en) | 2013-03-14 | 2014-10-02 | Mary Kay Inc. | Cosmetic compositions |
| ITMI20130807A1 (it) * | 2013-05-16 | 2014-11-17 | Indena Spa | Combinazioni di estratti di serenoa repens e di estratti lipofili di zingiber officinalis e di echinacea angustifolia, loro uso e formulazioni che li contengono |
| US10086033B2 (en) * | 2013-12-24 | 2018-10-02 | Innovative Herbal Products (Aust) Pty Ltd | Treatment of pain |
| BR112016018973B1 (pt) * | 2014-02-20 | 2021-01-19 | Indena S.P.A. | composição e uso de uma composição |
| CN103961482A (zh) * | 2014-04-23 | 2014-08-06 | 湖州康企药业有限公司 | 一种治疗皮炎的天然药物 |
| DE202015006894U1 (de) * | 2015-08-31 | 2015-12-21 | Dr. August Wolff Gmbh & Co. Kg Arzneimittel | Zusammensetzungen enthaltend einen Extrakt aus Echinacea und Linolsäurederivate |
| EP3150214A1 (en) * | 2015-10-01 | 2017-04-05 | INDENA S.p.A. | Compositions containing extracts of curcuma spp and zingiber officinale which are useful to reduce peripheral inflammation and pain |
| ITUB20161030A1 (it) * | 2016-02-24 | 2017-08-24 | Indena Spa | Composizioni utili nella prevenzione e/o nel trattamento dell’infiammazione e del dolore |
| ITUA20161822A1 (it) * | 2016-03-18 | 2017-09-18 | Indena Spa | Composizioni utili nella prevenzione e/o nel trattamento di patologie del cavo orale, delle prime vie aeree e dell’esofago |
| KR101684218B1 (ko) * | 2016-04-04 | 2016-12-07 | 이경복 | 통증 완화를 위한 에센셜 오일 |
| KR102657242B1 (ko) * | 2016-05-30 | 2024-04-12 | 시므라이즈 아게 | 스크라레올라이드 (sclareolide) 를 포함하는 화장품 조성물 |
| ITUA20164757A1 (it) * | 2016-06-29 | 2017-12-29 | Indena Spa | Composizioni utili nella prevenzione e/o nel trattamento dell’infiammazione e del dolore osteoarticolare e del danno cartilagineo |
| EP3335716A1 (en) * | 2016-12-15 | 2018-06-20 | Indena S.p.A. | Process for the preparation of powder compositions |
| EP3607959A1 (en) * | 2018-08-10 | 2020-02-12 | Raman Mehta | Formulations containing lipophilic extracts of spicy edible plants useful in controlling pain and inflammation |
| US11147835B1 (en) | 2020-08-20 | 2021-10-19 | Frank Kelly Reilly, III | Nutritional supplement |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2075187T3 (es) | 1990-07-05 | 1995-10-01 | Indena Spa | Extractos de equinaceas, un procedimiento para su preparacion y formulaciones que los contienen. |
| JP3030062B2 (ja) * | 1990-07-26 | 2000-04-10 | インデナ・ソチエタ・ペル・アチオニ | エキナセア抽出物、抽出物の製造方法及びそれらを含む製剤 |
| CA2307614A1 (en) * | 1997-10-23 | 1999-04-29 | Elliot P. Friedman | Pharmaceutical grade echinacea |
| US20010046523A1 (en) * | 2000-02-25 | 2001-11-29 | Thomas Newmark | Ginger-based herbal composition for promoting health and methods of using same |
| US6274177B1 (en) * | 2000-08-26 | 2001-08-14 | National Science Council | Method of preparing an extract potent in anti-inflammation and anti-platelet aggregation from Zingiber officinale and pharmaceutical compositions containing said extract |
| CN1279963C (zh) * | 2001-06-07 | 2006-10-18 | 财团法人制药工业技术发展中心 | 从姜制备含抗发炎、抗血小板凝集或抗菌活性的有效成分的产品及方法和产品的医药组成物 |
| US20030157185A1 (en) * | 2002-02-08 | 2003-08-21 | Lou Paradise | Topical treatment of neuropathy |
| ITMI20021691A1 (it) * | 2002-07-30 | 2004-01-30 | Indena Spa | Estratti di echinacea angustifolia |
| ITMI20032286A1 (it) * | 2003-11-24 | 2005-05-25 | Indena Spa | Composizioni per il trattamento di dermatiti atopiche di stati allergici cutanei e dell'acne |
| JP5303697B2 (ja) * | 2005-10-26 | 2013-10-02 | オリザ油化株式会社 | 抗炎症剤 |
| US7282224B1 (en) * | 2006-06-09 | 2007-10-16 | Guthy-Renker Corporation | Pain relief composition |
| US20080160116A1 (en) * | 2006-12-07 | 2008-07-03 | Herbalscience Singapore Pte. Ltd | Compositions and Methods Comprising Zingiber Species |
| CN101125136B (zh) * | 2006-12-26 | 2010-06-02 | 广东药学院 | 高良姜二苯基庚烷类化合物在镇痛抗炎中的应用及其提取方法 |
| EP2009023A1 (en) * | 2007-06-04 | 2008-12-31 | Rentschler Beteiligungs GmbH | Novel peptides and their use for the treatment of edema |
| US7824986B2 (en) * | 2008-11-05 | 2010-11-02 | Micron Technology, Inc. | Methods of forming a plurality of transistor gates, and methods of forming a plurality of transistor gates having at least two different work functions |
| ITMI20090049A1 (it) * | 2009-01-20 | 2010-07-21 | Indena Spa | Composizioni a base di estratti lipofili di zingiber officinale e di echinacea angustifolia per la prevenzione e il trattamento del riflusso gastro-esofageo e dell'emesi indotta da chemioterapici |
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2010
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